Moléculas que participan en el transporte materno-fetal de hierro: importancia del receptor 1 de transferrina y de la ferroportina en la placenta humana

ABSTRACT: An adequate placental transfer of iron is critical to satisfy the high fetal requirements of this mineral, and to promote proper intrauterine growth and development. It also contributes to the prevention of iron deficiency and anemia, both of which are very frequent during the first two years of life, and associate with increased rates of morbidity and mortality. Different adaptations may occur in the placenta in the production of molecules that take part in the mother-tofetus iron transfer. With them, iron availability to the fetus is assured. Our aim with this review is to familiarize readers with the metabolic and molecular mechanisms of placental iron uptake, transport, regulation and release. With this knowledge, the importance of an adequate maternal iron state before and during pregnancy may be better understood.

• Autores: Corrales Agudelo, Lady Vanessa; Parra Sosa, Beatríz Elena; Maldonado Estrada, Juan Guillermo; Burgos Herrera, Luis Carlos
• Tipo de recurso: Review article
• Fecha de publicación: 2011
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: spa
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/12959
• Acceso en línea: http://hdl.handle.net/10495/12959
• Palabra clave: Embarazo; Hierro; Nutrición Materna; Receptores de Transferrina
• Rights: openAccess
• License: Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)