In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
ABSTRACT : Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole. Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology. Results All the isolates were resist...
- Autores:
-
Gaviria Rivera, Adelaida
Giraldo López, Alejandra
Cano Restrepo, Luz Elena
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/28671
- Acceso en línea:
- http://hdl.handle.net/10495/28671
- Palabra clave:
- Fusarium
Anfotericina B
Amphotericin B
Voriconazol
Voriconazole
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
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| dc.title.spa.fl_str_mv |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| dc.title.alternative.spa.fl_str_mv |
Susceptibilidad antifúngica in vitro de aislamientos clínicos de Fusarium de Colombia |
| title |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| spellingShingle |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia Fusarium Anfotericina B Amphotericin B Voriconazol Voriconazole |
| title_short |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| title_full |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| title_fullStr |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| title_full_unstemmed |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| title_sort |
In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia |
| dc.creator.fl_str_mv |
Gaviria Rivera, Adelaida Giraldo López, Alejandra Cano Restrepo, Luz Elena |
| dc.contributor.author.none.fl_str_mv |
Gaviria Rivera, Adelaida Giraldo López, Alejandra Cano Restrepo, Luz Elena |
| dc.subject.decs.none.fl_str_mv |
Fusarium Anfotericina B Amphotericin B Voriconazol Voriconazole |
| topic |
Fusarium Anfotericina B Amphotericin B Voriconazol Voriconazole |
| description |
ABSTRACT : Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole. Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology. Results All the isolates were resistant to itraconazole, and 89 % and 54,5 % were resistant to amphotericin B and voriconazole, respectively. Discussion The results confirm the high level of resistance reported, regardless of the species or the strain of Fusarium involved. The high MICs level observed are worrying and suggest that new drugs are needed. |
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2017 |
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2017 |
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2022-05-26T13:19:08Z |
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2022-05-26T13:19:08Z |
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In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia Gaviria-Rivera,Adelaida Maria et al. Revista de Salud Pública(2017),19(6):800 http://dx.doi.org/10.15446/rsap.v19n6.54654 |
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0124-0064 |
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http://hdl.handle.net/10495/28671 |
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10.15446/rsap.v19n6.54654 |
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2539-3596 |
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In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia Gaviria-Rivera,Adelaida Maria et al. Revista de Salud Pública(2017),19(6):800 http://dx.doi.org/10.15446/rsap.v19n6.54654 0124-0064 10.15446/rsap.v19n6.54654 2539-3596 |
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http://hdl.handle.net/10495/28671 |
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eng |
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eng |
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Rev. Salud Pública. |
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Universidad Nacional de Colombia, Facultad de Medicina, Instituto de Salud Pública |
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Micología Médica y Experimental |
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Bogotá, Colombia |
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Universidad de Antioquia |
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Gaviria Rivera, AdelaidaGiraldo López, AlejandraCano Restrepo, Luz Elena2022-05-26T13:19:08Z2022-05-26T13:19:08Z2017In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia Gaviria-Rivera,Adelaida Maria et al. Revista de Salud Pública(2017),19(6):800 http://dx.doi.org/10.15446/rsap.v19n6.546540124-0064http://hdl.handle.net/10495/2867110.15446/rsap.v19n6.546542539-3596ABSTRACT : Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole. Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology. Results All the isolates were resistant to itraconazole, and 89 % and 54,5 % were resistant to amphotericin B and voriconazole, respectively. Discussion The results confirm the high level of resistance reported, regardless of the species or the strain of Fusarium involved. The high MICs level observed are worrying and suggest that new drugs are needed.RESUMEN : Objetivo Evaluar la susceptibilidad antifúngica in vitro de aislamientos de Fusarium a los antimicóticos amfotericina B, itraconazol y voriconazol. Métodos La susceptibilidad de 44 aislamientos clínicos de Fusarium fue evaluada por el método de difusión en disco, E-test. Resultados Todos los aislamientos fueron resistentes al itraconazol, y 89 % y 54,5 % fueron resistentes a la amfotericina B y al voriconazol, respectivamente. Discusión Los resultados confirman el alto nivel de resistencia reportado, independiente de la especie o la cepa de Fusarium involucrada. Los valores tan altos de MICs son preocupantes y sugieren la necesidad de evaluar nuevos medicamentos.COL00137096application/pdfengUniversidad Nacional de Colombia, Facultad de Medicina, Instituto de Salud PúblicaMicología Médica y ExperimentalBogotá, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/In vitro antifungal susceptibility of clinical isolates of Fusarium from ColombiaSusceptibilidad antifúngica in vitro de aislamientos clínicos de Fusarium de ColombiaFusariumAnfotericina BAmphotericin BVoriconazolVoriconazoleRev. Salud Pública.Revista de Salud Pública800805196ORIGINALCanoLuz_2017_InvitroClinicalIsolates.pdfCanoLuz_2017_InvitroClinicalIsolates.pdfArtículo de investigaciónapplication/pdf337682http://bibliotecadigital.udea.edu.co/bitstream/10495/28671/1/CanoLuz_2017_InvitroClinicalIsolates.pdf876e0bd445fbbc60ecd71a4561a6fdafMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927http://bibliotecadigital.udea.edu.co/bitstream/10495/28671/2/license_rdf1646d1f6b96dbbbc38035efc9239ac9cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/28671/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/28671oai:bibliotecadigital.udea.edu.co:10495/286712022-05-26 08:19:09.187Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |