In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia

ABSTRACT : Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole. Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology. Results All the isolates were resist...

Full description

Autores:
Gaviria Rivera, Adelaida
Giraldo López, Alejandra
Cano Restrepo, Luz Elena
Tipo de recurso:
Article of investigation
Fecha de publicación:
2017
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/28671
Acceso en línea:
http://hdl.handle.net/10495/28671
Palabra clave:
Fusarium
Anfotericina B
Amphotericin B
Voriconazol
Voriconazole
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/
Description
Summary:ABSTRACT : Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole. Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology. Results All the isolates were resistant to itraconazole, and 89 % and 54,5 % were resistant to amphotericin B and voriconazole, respectively. Discussion The results confirm the high level of resistance reported, regardless of the species or the strain of Fusarium involved. The high MICs level observed are worrying and suggest that new drugs are needed.