Vías implicadas en la luteólisis bovina

ABSTRACT: The corpus luteum is a transient gland that produces progesterone during a period of time that is determined by the length of gestation. When there is no gestation the corpus luteum undergoes regression, a process commonly known as luteolysis. This process has been divided in: functional, since there is a lost of the capacity to synthesize progesterone; and structural, because there is a disruption of the cellular structure. PGF2α, is the principal luteolytic factor, but there are other parallel pathway mediated by calcium, cytokines, reactive oxygen species and endothelins. All these routes end up in inhibition of steroidogenesis and/or apoptosis. In this article we try to integrate the information present in the literature and propose a map depicting the major cellular and molecular events taking place in this process that is fundamental en bovine reproduction.

• Autores: Olivera Ángel, Martha; Tarazona Morales, Ariel Marcel; Ruiz Cortés, Zulma Tatiana; Giraldo Echeverri, Carlos Andrés
• Tipo de recurso: Review article
• Fecha de publicación: 2007
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: spa
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/8003
• Acceso en línea: http://hdl.handle.net/10495/8003
• Rights: openAccess
• License: Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)