A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America
ABSTRACT: We examined the mtDNA RFLP diversity of 17 Native American populations from Colombia. Five of the populations studied were found to have variable frequencies of a mtDNA type lacking the characteristic changes of haplogroups A-D. Sequencing of mtDNA HVS-I and II showed that this ‘‘null’’ RF...
- Autores:
-
Torres Carvajal, María de la Merced
Bravi, Claudio Marcelo
Bortolini, María Cátira
Duque Vélez, Constanza Elena
Callegari Jacques, Sidia Maria
Ortíz Barrientos, Daniel
Bedoya Berrío, Gabriel de Jesús
Groot de Restrepo, Helena
Ruíz Linares, Andrés
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2006
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/26750
- Acceso en línea:
- http://hdl.handle.net/10495/26750
- Palabra clave:
- Colombia - etnología
Colombia - ethnology
ADN Mitocondrial - genética
DNA, Mitochondrial - genetics
Efecto Fundador
Founder Effect
Genética de Población
Genetics, Population
Indios Sudamericanos
Indians, South American
Polimorfismo de Longitud del Fragmento de Restricción
Polymorphism, Restriction Fragment Length
Análisis de Secuencia de ADN
Sequence Analysis, DNA
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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| dc.title.spa.fl_str_mv |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| title |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| spellingShingle |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America Colombia - etnología Colombia - ethnology ADN Mitocondrial - genética DNA, Mitochondrial - genetics Efecto Fundador Founder Effect Genética de Población Genetics, Population Indios Sudamericanos Indians, South American Polimorfismo de Longitud del Fragmento de Restricción Polymorphism, Restriction Fragment Length Análisis de Secuencia de ADN Sequence Analysis, DNA |
| title_short |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| title_full |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| title_fullStr |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| title_full_unstemmed |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| title_sort |
A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South America |
| dc.creator.fl_str_mv |
Torres Carvajal, María de la Merced Bravi, Claudio Marcelo Bortolini, María Cátira Duque Vélez, Constanza Elena Callegari Jacques, Sidia Maria Ortíz Barrientos, Daniel Bedoya Berrío, Gabriel de Jesús Groot de Restrepo, Helena Ruíz Linares, Andrés |
| dc.contributor.author.none.fl_str_mv |
Torres Carvajal, María de la Merced Bravi, Claudio Marcelo Bortolini, María Cátira Duque Vélez, Constanza Elena Callegari Jacques, Sidia Maria Ortíz Barrientos, Daniel Bedoya Berrío, Gabriel de Jesús Groot de Restrepo, Helena Ruíz Linares, Andrés |
| dc.subject.decs.none.fl_str_mv |
Colombia - etnología Colombia - ethnology ADN Mitocondrial - genética DNA, Mitochondrial - genetics Efecto Fundador Founder Effect Genética de Población Genetics, Population Indios Sudamericanos Indians, South American Polimorfismo de Longitud del Fragmento de Restricción Polymorphism, Restriction Fragment Length Análisis de Secuencia de ADN Sequence Analysis, DNA |
| topic |
Colombia - etnología Colombia - ethnology ADN Mitocondrial - genética DNA, Mitochondrial - genetics Efecto Fundador Founder Effect Genética de Población Genetics, Population Indios Sudamericanos Indians, South American Polimorfismo de Longitud del Fragmento de Restricción Polymorphism, Restriction Fragment Length Análisis de Secuencia de ADN Sequence Analysis, DNA |
| description |
ABSTRACT: We examined the mtDNA RFLP diversity of 17 Native American populations from Colombia. Five of the populations studied were found to have variable frequencies of a mtDNA type lacking the characteristic changes of haplogroups A-D. Sequencing of mtDNA HVS-I and II showed that this ‘‘null’’ RFLP type carries all the substitutions characteristic of Native American founder lineage C. A back mutation has therefore recreated theþ13,259HincII/ 13,262AluI restriction sites that typify RFLP haplogroup C. This revertant C lineage is further characterized by three changes in HVS-II sequence: C/T transitions at positions 115 and 152, and the deletion of an A residue at position 116. This lineage is observed at high frequency mostly in populations from Greenberg’s Equatorial–Tucano linguistic family. Genetic structure analyses are consistent with the reversion mutation occurring at an early stage during the tribalization process. |
| publishDate |
2006 |
| dc.date.issued.none.fl_str_mv |
2006 |
| dc.date.accessioned.none.fl_str_mv |
2022-03-19T21:28:01Z |
| dc.date.available.none.fl_str_mv |
2022-03-19T21:28:01Z |
| dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
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Artículo de investigación |
| format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
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publishedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Torres, M., Bravi, C., Bortolini, M., Duque, C., Callegari, S., Ortiz, D., Bedoya, G., Groot, H. and Ruiz, A. (2006). A revertant of the major founder Native American haplogroup C common in populations from northern South America. Am. J. Hum. Biol., 18: 59-65. https://doi.org/10.1002/ajhb.20461 |
| dc.identifier.issn.none.fl_str_mv |
1042-0533 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/26750 |
| dc.identifier.doi.none.fl_str_mv |
10.1002/ajhb.20461 |
| dc.identifier.eissn.none.fl_str_mv |
1520-6300 |
| identifier_str_mv |
Torres, M., Bravi, C., Bortolini, M., Duque, C., Callegari, S., Ortiz, D., Bedoya, G., Groot, H. and Ruiz, A. (2006). A revertant of the major founder Native American haplogroup C common in populations from northern South America. Am. J. Hum. Biol., 18: 59-65. https://doi.org/10.1002/ajhb.20461 1042-0533 10.1002/ajhb.20461 1520-6300 |
| url |
http://hdl.handle.net/10495/26750 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Am. J. Hum. Biol. |
| dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
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http://purl.org/coar/access_right/c_abf2 |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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http://creativecommons.org/licenses/by-nc-nd/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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7 |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
Wiley-Blackwell |
| dc.publisher.group.spa.fl_str_mv |
Genética Molecular (GENMOL) |
| dc.publisher.place.spa.fl_str_mv |
Nueva York, Estados Unidos |
| institution |
Universidad de Antioquia |
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Torres Carvajal, María de la MercedBravi, Claudio MarceloBortolini, María CátiraDuque Vélez, Constanza ElenaCallegari Jacques, Sidia MariaOrtíz Barrientos, DanielBedoya Berrío, Gabriel de JesúsGroot de Restrepo, HelenaRuíz Linares, Andrés2022-03-19T21:28:01Z2022-03-19T21:28:01Z2006Torres, M., Bravi, C., Bortolini, M., Duque, C., Callegari, S., Ortiz, D., Bedoya, G., Groot, H. and Ruiz, A. (2006). A revertant of the major founder Native American haplogroup C common in populations from northern South America. Am. J. Hum. Biol., 18: 59-65. https://doi.org/10.1002/ajhb.204611042-0533http://hdl.handle.net/10495/2675010.1002/ajhb.204611520-6300ABSTRACT: We examined the mtDNA RFLP diversity of 17 Native American populations from Colombia. Five of the populations studied were found to have variable frequencies of a mtDNA type lacking the characteristic changes of haplogroups A-D. Sequencing of mtDNA HVS-I and II showed that this ‘‘null’’ RFLP type carries all the substitutions characteristic of Native American founder lineage C. A back mutation has therefore recreated theþ13,259HincII/ 13,262AluI restriction sites that typify RFLP haplogroup C. This revertant C lineage is further characterized by three changes in HVS-II sequence: C/T transitions at positions 115 and 152, and the deletion of an A residue at position 116. This lineage is observed at high frequency mostly in populations from Greenberg’s Equatorial–Tucano linguistic family. Genetic structure analyses are consistent with the reversion mutation occurring at an early stage during the tribalization process.COL00067237application/pdfengWiley-BlackwellGenética Molecular (GENMOL)Nueva York, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/A Revertant of the Major Founder Native American HaplogroupC Common in Populations From Northern South AmericaColombia - etnologíaColombia - ethnologyADN Mitocondrial - genéticaDNA, Mitochondrial - geneticsEfecto FundadorFounder EffectGenética de PoblaciónGenetics, PopulationIndios SudamericanosIndians, South AmericanPolimorfismo de Longitud del Fragmento de RestricciónPolymorphism, Restriction Fragment LengthAnálisis de Secuencia de ADNSequence Analysis, DNAAm. J. Hum. Biol.American Journal of Human Biology5965181CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8823http://bibliotecadigital.udea.edu.co/bitstream/10495/26750/2/license_rdfb88b088d9957e670ce3b3fbe2eedbc13MD52ORIGINALDuqueConstanza_2006_NativeAmericanHaplogroup.pdfDuqueConstanza_2006_NativeAmericanHaplogroup.pdfArtículo de investigaciónapplication/pdf211639http://bibliotecadigital.udea.edu.co/bitstream/10495/26750/1/DuqueConstanza_2006_NativeAmericanHaplogroup.pdfe509f8038f19b77afd885286774c3767MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/26750/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/26750oai:bibliotecadigital.udea.edu.co:10495/267502022-03-19 16:28:01.716Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |