Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011

ABSTRACT: Treatment for latent tuberculosis decreases the risk of this infection in children who are household contacts of patients with such disease. Objective: To describe the study and clinical management of children under 5 years of age who were household contacts of pulmonary tuberculosis patie...

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Autores:
Benjumea Bedoya, Dione
Arbeláez Montoya, María Patricia
Tipo de recurso:
Article of investigation
Fecha de publicación:
2015
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
spa
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/11481
Acceso en línea:
http://hdl.handle.net/10495/11481
Palabra clave:
Isoniazida
Desarrollo Infantil
Mycobacterium tuberculosis
Tuberculosis Latente
Rights
openAccess
License
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
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oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/11481
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
title Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
spellingShingle Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
Isoniazida
Desarrollo Infantil
Mycobacterium tuberculosis
Tuberculosis Latente
title_short Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
title_full Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
title_fullStr Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
title_full_unstemmed Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
title_sort Estudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011
dc.creator.fl_str_mv Benjumea Bedoya, Dione
Arbeláez Montoya, María Patricia
dc.contributor.author.none.fl_str_mv Benjumea Bedoya, Dione
Arbeláez Montoya, María Patricia
dc.subject.none.fl_str_mv Isoniazida
Desarrollo Infantil
Mycobacterium tuberculosis
Tuberculosis Latente
topic Isoniazida
Desarrollo Infantil
Mycobacterium tuberculosis
Tuberculosis Latente
description ABSTRACT: Treatment for latent tuberculosis decreases the risk of this infection in children who are household contacts of patients with such disease. Objective: To describe the study and clinical management of children under 5 years of age who were household contacts of pulmonary tuberculosis patients in Medellin, Colombia during the period 2010-2011. Materials and methods: Cross-sectional study. The relationship between socio-demographic and clinical characteristics, and the management of children and index cases was explored. Results: 28.6% were studied with at least chest X rays and tuberculin skin test. Of those who attended clinical evaluation, 7.9% had active tuberculosis; out of the remaining, 19.4% received treatment for latent tuberculosis. The probability of being studied was higher if the household contact had contributory or subsidized health coverage (adjusted OR: 6.7; 95% CI: 1.5-30.5). The opportunity to receive treatment for latent tuberculosis was related to the tuberculin skin test (adjusted OR: 40.2; 95% CI: 2.59-623.6). Conclusion: The household contacts had not been adequately studied, and did not receive the right treatment, so the prevalence of active tuberculosis among them did not decrease. It is necessary to establish a standardized protocol for the management of children living under similar conditions, and to monitor its implementation. Key words: Isoniazid, Latent Tuberculosis, Preschool, Tuberculosis.
publishDate 2015
dc.date.issued.none.fl_str_mv 2015
dc.date.accessioned.none.fl_str_mv 2019-07-22T20:51:02Z
dc.date.available.none.fl_str_mv 2019-07-22T20:51:02Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.type.local.spa.fl_str_mv Artículo de investigación
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status_str publishedVersion
dc.identifier.citation.spa.fl_str_mv Benjumea Bedoya D, Arbeláez Montoya MP. Estudio y manejo clínico de menores convivientes de pacientes con tuberculosis pulmonar, Medellín 2010-2011. Iatreia. 2015 Abr-Jun;28(2):137-147. DOI 10.17533/udea.iatreia.v28n2a04
dc.identifier.issn.none.fl_str_mv 0121-0793
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/11481
dc.identifier.doi.none.fl_str_mv 10.17533/udea.iatreia.v28n2a04
dc.identifier.eissn.none.fl_str_mv 2011-7965
identifier_str_mv Benjumea Bedoya D, Arbeláez Montoya MP. Estudio y manejo clínico de menores convivientes de pacientes con tuberculosis pulmonar, Medellín 2010-2011. Iatreia. 2015 Abr-Jun;28(2):137-147. DOI 10.17533/udea.iatreia.v28n2a04
0121-0793
10.17533/udea.iatreia.v28n2a04
2011-7965
url http://hdl.handle.net/10495/11481
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Iatreia
dc.rights.*.fl_str_mv Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
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dc.rights.creativecommons.spa.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0/
rights_invalid_str_mv Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
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dc.format.extent.spa.fl_str_mv 10
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad de Antioquia, Facultad de Medicina
dc.publisher.place.spa.fl_str_mv Medellín, Colombia
institution Universidad de Antioquia
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spelling Benjumea Bedoya, DioneArbeláez Montoya, María Patricia2019-07-22T20:51:02Z2019-07-22T20:51:02Z2015Benjumea Bedoya D, Arbeláez Montoya MP. Estudio y manejo clínico de menores convivientes de pacientes con tuberculosis pulmonar, Medellín 2010-2011. Iatreia. 2015 Abr-Jun;28(2):137-147. DOI 10.17533/udea.iatreia.v28n2a040121-0793http://hdl.handle.net/10495/1148110.17533/udea.iatreia.v28n2a042011-7965ABSTRACT: Treatment for latent tuberculosis decreases the risk of this infection in children who are household contacts of patients with such disease. Objective: To describe the study and clinical management of children under 5 years of age who were household contacts of pulmonary tuberculosis patients in Medellin, Colombia during the period 2010-2011. Materials and methods: Cross-sectional study. The relationship between socio-demographic and clinical characteristics, and the management of children and index cases was explored. Results: 28.6% were studied with at least chest X rays and tuberculin skin test. Of those who attended clinical evaluation, 7.9% had active tuberculosis; out of the remaining, 19.4% received treatment for latent tuberculosis. The probability of being studied was higher if the household contact had contributory or subsidized health coverage (adjusted OR: 6.7; 95% CI: 1.5-30.5). The opportunity to receive treatment for latent tuberculosis was related to the tuberculin skin test (adjusted OR: 40.2; 95% CI: 2.59-623.6). Conclusion: The household contacts had not been adequately studied, and did not receive the right treatment, so the prevalence of active tuberculosis among them did not decrease. It is necessary to establish a standardized protocol for the management of children living under similar conditions, and to monitor its implementation. Key words: Isoniazid, Latent Tuberculosis, Preschool, Tuberculosis.RESUMEN: El tratamiento para tuberculosis latente disminuye el riesgo de infección de los niños que conviven con pacientes de dicha enfermedad. Objetivo: describir el estudio y manejo clínico de los menores de 5 años que convivían en Medellín con pacientes de tuberculosis pulmonar en el período 2010-1011. Materiales y métodos: estudio observacional de corte. Se exploró la relación entre las características sociodemográficas, clínicas y de manejo de los niños y los casos índice. Resultados: 28,6% fueron estudiados al menos con radiografía de tórax y prueba de tuberculina. De los evaluados clínicamente, 7,9% tenían tuberculosis activa; de los demás, 19,4% recibieron tratamiento para tuberculosis latente. Hubo mayor oportunidad de ser estudiado si el conviviente tenía régimen de salud contributivo o subsidiado (OR ajustado: 6,7; IC 95%: 1,5-30,5). La oportunidad de recibir tratamiento para tuberculosis latente se relacionó con la prueba de tuberculina (OR ajustado: 40,2; IC 95%: 2,59-623,6). Conclusión: los menores no estaban siendo adecuadamente estudiados ni recibían el tratamiento apropiado, por lo que su prevalencia de tuberculosis activa no disminuyó. Se requiere crear un protocolo estandarizado para el manejo de los menores en similares condiciones y supervisar su aplicación. Palabras clave: Isoniazida, Preescolar, Tuberculosis, Tuberculosis latente.10application/pdfspaUniversidad de Antioquia, Facultad de MedicinaMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/IsoniazidaDesarrollo InfantilMycobacterium tuberculosisTuberculosis LatenteEstudio y manejo clínico de menores que conviven con pacientes de tuberculosis pulmonar, Medellín 2010-2011IatreiaIatreia137147282ORIGINALMenoresconviventuberculosis_2015_DioneBenjumeaBedoya.pdfMenoresconviventuberculosis_2015_DioneBenjumeaBedoya.pdfapplication/pdf147036https://bibliotecadigital.udea.edu.co/bitstream/10495/11481/1/Menoresconviventuberculosis_2015_DioneBenjumeaBedoya.pdfe698dd12cd50739c3eb10c9a298beb35MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849https://bibliotecadigital.udea.edu.co/bitstream/10495/11481/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80https://bibliotecadigital.udea.edu.co/bitstream/10495/11481/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80https://bibliotecadigital.udea.edu.co/bitstream/10495/11481/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/11481/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5510495/11481oai:bibliotecadigital.udea.edu.co:10495/114812022-06-30 09:55:58.349Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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