Antiprotozoal Activity of a,b-Unsaturated Lactones: Promising Compounds for the Development of New Therapeutic Alternatives
ABSTRACT: The parasite resistance and side effects of drugs used to treat protozoal diseases have led to the search for new therapies, both natural and synthetic. Studies have shown that various α,β-unsaturated δlactones displayed high antiprotozoal activity and thus are promising compounds for new...
- Autores:
-
Wilson, Cardona Galeano
Saez Vega, Jairo Antonio
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/30994
- Acceso en línea:
- https://hdl.handle.net/10495/30994
https://www.ajol.info/index.php/tjpr/article/view/71710
- Palabra clave:
- Antiparasitarios
Antiparasitic Agents
Lactonas
Lactones
Pironas
Pyrones
Leishmania
Malaria
Plasmodium falciparum
Trypanosoma cruzi
Antiprotozoarios
Antiprotozoal Agents
Enfermedad de Chagas
Chagas Disease
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
| Summary: | ABSTRACT: The parasite resistance and side effects of drugs used to treat protozoal diseases have led to the search for new therapies, both natural and synthetic. Studies have shown that various α,β-unsaturated δlactones displayed high antiprotozoal activity and thus are promising compounds for new drug discovery and development. These compounds and their activity are examined in this review. |
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