Autovaloración de calidad de vida y envejecimiento en adultos con riesgo de Alzheimer

ABSTRACT: middle-age adult carriers and non-carriers of mutation E280A in gene Presenilin 1 for Early Onset Familial Alzheimer’s Disease and of elderly adults in Antioquia-Colombia. Study conducted from January 2005 to June 2007. Methodology: descriptive transversal study in which 162 asymptomatic p...

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Autores:: Zea Herrera, María del Carmen
López Alzate, María Elizabeth
Valencia Marín, Claudia Marcela
Soto Gómez, Juliana Andrea
Aguirre Acevedo, Daniel Camilo
Lopera Restrepo, Francisco Javier
Oswald, Wolf
Rupprecht, Roland

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2008

Institución:: Universidad de Antioquia

Repositorio:: Repositorio UdeA

Idioma:: spa

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Summary:	ABSTRACT: middle-age adult carriers and non-carriers of mutation E280A in gene Presenilin 1 for Early Onset Familial Alzheimer’s Disease and of elderly adults in Antioquia-Colombia. Study conducted from January 2005 to June 2007. Methodology: descriptive transversal study in which 162 asymptomatic people at risk of developing Alzheimer’s disease as a genetic consequence or as a consequence of the process of aging. They were subdivided into three groups: 27 carriers of the mutation, 39 non-carriers and 96 elderly adults. The study was conducted at the Neuroscience Group in Medellín (Antioquia) and at a gerontology center in Envigado (Antioquia) named Atardecer. Social-demographic characteristics were analyzed and quality of life and overall aging selfassessment tests were applied, which included the World Health Organization Quality of Life, and the Nürnberg -Self-Evaluation-List respectively. Statistic Analysis: The groups were described and they were compared to the variables of the study using Kruskall Wallis non-parametric ANOVA and Mann-Whitney’s U-test. Results: the mean scores of the instruments to assess quality of life and overall aging of three groups of participants were above 50 points and below 55 points respectively. Conclusions: elderly adults assessed themselves as having a lower quality of life than carriers and non-carriers, especially in the physical health area, and in their perception of aging, in spite of carriers’ conditions, although in general the scores were good in all the groups.

Autovaloración de calidad de vida y envejecimiento en adultos con riesgo de Alzheimer

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