Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpi...
- Autores:
-
Gómez Betancur, Isabel Cristina
Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2019
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/20250
- Acceso en línea:
- http://hdl.handle.net/10495/20250
- Palabra clave:
- Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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oai:bibliotecadigital.udea.edu.co:10495/20250 |
network_acronym_str |
UDEA2 |
network_name_str |
Repositorio UdeA |
repository_id_str |
|
dc.title.spa.fl_str_mv |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
title |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
spellingShingle |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas Aceites esenciales Essential oils Extractos de hoja Leaf extracts Micropropagación Micropropagation Renealmia alpinia Antinociceptive http://aims.fao.org/aos/agrovoc/c_2669 http://aims.fao.org/aos/agrovoc/c_35308 http://aims.fao.org/aos/agrovoc/c_24136 |
title_short |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
title_full |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
title_fullStr |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
title_full_unstemmed |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
title_sort |
Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas |
dc.creator.fl_str_mv |
Gómez Betancur, Isabel Cristina Benjumea Gutiérrez, Dora María Mejía, Natalia León, Juan F. Gómez, Juan E. |
dc.contributor.author.none.fl_str_mv |
Gómez Betancur, Isabel Cristina Benjumea Gutiérrez, Dora María Mejía, Natalia León, Juan F. Gómez, Juan E. |
dc.subject.agrovoc.none.fl_str_mv |
Aceites esenciales Essential oils Extractos de hoja Leaf extracts Micropropagación Micropropagation |
topic |
Aceites esenciales Essential oils Extractos de hoja Leaf extracts Micropropagación Micropropagation Renealmia alpinia Antinociceptive http://aims.fao.org/aos/agrovoc/c_2669 http://aims.fao.org/aos/agrovoc/c_35308 http://aims.fao.org/aos/agrovoc/c_24136 |
dc.subject.proposal.spa.fl_str_mv |
Renealmia alpinia Antinociceptive |
dc.subject.agrovocuri.none.fl_str_mv |
http://aims.fao.org/aos/agrovoc/c_2669 http://aims.fao.org/aos/agrovoc/c_35308 http://aims.fao.org/aos/agrovoc/c_24136 |
description |
ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpinia leave-extracts have shown enzymatic inhibition of Bothrops atrox and Bothrops asper snake poison. The extracts also showed effects as a peripheral analgesic agent. This report investigates the analgesic activity of the essential oils obtained by hydrodistillation from wild and in vitro propagation samples of R. alpinia as well as the chemical profile using GC-MS. The essential oils isolated from R. alpinia evaluated on concentrations of 50, 75 and 100 mg/kg showed significant antinociceptive effects in the test of acetic-acid-induced abdominal writhing, compared to the control animals. The essential oil of the wild flora leaves showed the highest percentage of pain inhibition by 200 mg/kg, concluding that the essential oil of R. alpinia presents antinociceptive activity in an in vivo model. These results help us to understand the traditional use of R. alpinia to treat pain and make it a potential source for the development of phytopharmaceutics. |
publishDate |
2019 |
dc.date.issued.none.fl_str_mv |
2019 |
dc.date.accessioned.none.fl_str_mv |
2021-06-22T22:34:27Z |
dc.date.available.none.fl_str_mv |
2021-06-22T22:34:27Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
dc.type.local.spa.fl_str_mv |
Artículo de investigación |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
status_str |
publishedVersion |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/20250 |
dc.identifier.doi.none.fl_str_mv |
10.25135/rnp.70.18.01.084 |
dc.identifier.eissn.none.fl_str_mv |
1307-6167 |
url |
http://hdl.handle.net/10495/20250 |
identifier_str_mv |
10.25135/rnp.70.18.01.084 1307-6167 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Rec. Nat. Prod. |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.format.extent.spa.fl_str_mv |
8 |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Acg Publishing Press Release |
dc.publisher.group.spa.fl_str_mv |
Toxinología Alternativas Terapéuticas y Alimentarias |
dc.publisher.place.spa.fl_str_mv |
Turquía |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
http://bibliotecadigital.udea.edu.co/bitstream/10495/20250/1/BenjumeaDora_2019_AntinociceptiveActivityEssential.pdf http://bibliotecadigital.udea.edu.co/bitstream/10495/20250/2/license_rdf http://bibliotecadigital.udea.edu.co/bitstream/10495/20250/3/license.txt |
bitstream.checksum.fl_str_mv |
167f537ab8486f98692b30f808a38085 b88b088d9957e670ce3b3fbe2eedbc13 8a4605be74aa9ea9d79846c1fba20a33 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
_version_ |
1812173228803620864 |
spelling |
Gómez Betancur, Isabel CristinaBenjumea Gutiérrez, Dora MaríaMejía, NataliaLeón, Juan F.Gómez, Juan E.2021-06-22T22:34:27Z2021-06-22T22:34:27Z2019http://hdl.handle.net/10495/2025010.25135/rnp.70.18.01.0841307-6167ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpinia leave-extracts have shown enzymatic inhibition of Bothrops atrox and Bothrops asper snake poison. The extracts also showed effects as a peripheral analgesic agent. This report investigates the analgesic activity of the essential oils obtained by hydrodistillation from wild and in vitro propagation samples of R. alpinia as well as the chemical profile using GC-MS. The essential oils isolated from R. alpinia evaluated on concentrations of 50, 75 and 100 mg/kg showed significant antinociceptive effects in the test of acetic-acid-induced abdominal writhing, compared to the control animals. The essential oil of the wild flora leaves showed the highest percentage of pain inhibition by 200 mg/kg, concluding that the essential oil of R. alpinia presents antinociceptive activity in an in vivo model. These results help us to understand the traditional use of R. alpinia to treat pain and make it a potential source for the development of phytopharmaceutics.COL00144768application/pdfengAcg Publishing Press ReleaseToxinología Alternativas Terapéuticas y AlimentariasTurquíainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) MaasAceites esencialesEssential oilsExtractos de hojaLeaf extractsMicropropagaciónMicropropagationRenealmia alpiniaAntinociceptivehttp://aims.fao.org/aos/agrovoc/c_2669http://aims.fao.org/aos/agrovoc/c_35308http://aims.fao.org/aos/agrovoc/c_24136Rec. Nat. Prod.Records of Natural Products1017131ORIGINALBenjumeaDora_2019_AntinociceptiveActivityEssential.pdfBenjumeaDora_2019_AntinociceptiveActivityEssential.pdfArtículo de investigaciónapplication/pdf594857http://bibliotecadigital.udea.edu.co/bitstream/10495/20250/1/BenjumeaDora_2019_AntinociceptiveActivityEssential.pdf167f537ab8486f98692b30f808a38085MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8823http://bibliotecadigital.udea.edu.co/bitstream/10495/20250/2/license_rdfb88b088d9957e670ce3b3fbe2eedbc13MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/20250/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/20250oai:bibliotecadigital.udea.edu.co:10495/202502021-06-22 17:34:27.804Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |