Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia
ABSTRACT: We conducted a case-control study to evaluate risk factors for visceral leishmaniasis during an epidemic in a previously unaffected district of Ethiopia. We also collected blood and bone marrow specimens from dogs in the outbreak villages. In multivariable analyses of 171 matched case-cont...
- Autores:
-
Vélez Bernal, Iván Darío
Bashaye, Seife
Nombela, Nohelly
Argaw, Daniel
Mulugeta, Abate
Herrero, Merce
Nieto, Javier
Chicharro, Carmen
Cañavate, Carmen
Aparicio, Pilar
Alvar, Jorge
Bern, Caryn
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2009
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/32117
- Acceso en línea:
- https://hdl.handle.net/10495/32117
- Palabra clave:
- Leishmaniasis Visceral
Leishmaniasis, Visceral
Enfermedades de los Perros
Dog Diseases
Etiopía
Ethiopia
Preescolar
Child, Preschool
Estudios de Casos y Controles
Case-Control Studies
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
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| dc.title.spa.fl_str_mv |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| title |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| spellingShingle |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia Leishmaniasis Visceral Leishmaniasis, Visceral Enfermedades de los Perros Dog Diseases Etiopía Ethiopia Preescolar Child, Preschool Estudios de Casos y Controles Case-Control Studies |
| title_short |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| title_full |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| title_fullStr |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| title_full_unstemmed |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| title_sort |
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, Ethiopia |
| dc.creator.fl_str_mv |
Vélez Bernal, Iván Darío Bashaye, Seife Nombela, Nohelly Argaw, Daniel Mulugeta, Abate Herrero, Merce Nieto, Javier Chicharro, Carmen Cañavate, Carmen Aparicio, Pilar Alvar, Jorge Bern, Caryn |
| dc.contributor.author.none.fl_str_mv |
Vélez Bernal, Iván Darío Bashaye, Seife Nombela, Nohelly Argaw, Daniel Mulugeta, Abate Herrero, Merce Nieto, Javier Chicharro, Carmen Cañavate, Carmen Aparicio, Pilar Alvar, Jorge Bern, Caryn |
| dc.subject.decs.none.fl_str_mv |
Leishmaniasis Visceral Leishmaniasis, Visceral Enfermedades de los Perros Dog Diseases Etiopía Ethiopia Preescolar Child, Preschool Estudios de Casos y Controles Case-Control Studies |
| topic |
Leishmaniasis Visceral Leishmaniasis, Visceral Enfermedades de los Perros Dog Diseases Etiopía Ethiopia Preescolar Child, Preschool Estudios de Casos y Controles Case-Control Studies |
| description |
ABSTRACT: We conducted a case-control study to evaluate risk factors for visceral leishmaniasis during an epidemic in a previously unaffected district of Ethiopia. We also collected blood and bone marrow specimens from dogs in the outbreak villages. In multivariable analyses of 171 matched case-control pairs, dog ownership, sleeping under an acacia tree during the day, and habitually sleeping outside at night were associated with significantly increased risk. Specimens from 7 (3.8%) dogs were positive by immunofluorescent antibody test (IFAT) and both enzyme-linked immunosorbent assays (ELISAs), whereas Leishmania DNA was detected in 5 (2.8%) bone marrow aspirates (from 3 seropositive and 2 seronegative dogs). Insecticide-treated nets may only protect a portion of those at risk. Further research on the vectors, the role of the dog in the transmission cycle, and the effect of candidate interventions are needed to design the best strategy for control. |
| publishDate |
2009 |
| dc.date.issued.none.fl_str_mv |
2009 |
| dc.date.accessioned.none.fl_str_mv |
2022-11-17T18:40:07Z |
| dc.date.available.none.fl_str_mv |
2022-11-17T18:40:07Z |
| dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
| dc.type.local.spa.fl_str_mv |
Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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publishedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Bashaye S, Nombela N, Argaw D, Mulugeta A, Herrero M, Nieto J, Chicharro C, Cañavate C, Aparicio P, Vélez ID, Alvar J, Bern C. Risk factors for visceral leishmaniasis in a new epidemic site in Amhara Region, Ethiopia. Am J Trop Med Hyg. 2009 Jul;81(1):34-9. |
| dc.identifier.issn.none.fl_str_mv |
0002-9637 |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/32117 |
| dc.identifier.doi.none.fl_str_mv |
10.4269/ajtmh.2009.81.34 |
| dc.identifier.eissn.none.fl_str_mv |
1476-1645 |
| identifier_str_mv |
Bashaye S, Nombela N, Argaw D, Mulugeta A, Herrero M, Nieto J, Chicharro C, Cañavate C, Aparicio P, Vélez ID, Alvar J, Bern C. Risk factors for visceral leishmaniasis in a new epidemic site in Amhara Region, Ethiopia. Am J Trop Med Hyg. 2009 Jul;81(1):34-9. 0002-9637 10.4269/ajtmh.2009.81.34 1476-1645 |
| url |
https://hdl.handle.net/10495/32117 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Am. J. Trop. Med. Hyg. |
| dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by/2.5/co/ |
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http://purl.org/coar/access_right/c_abf2 |
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https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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http://creativecommons.org/licenses/by/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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6 |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
American Society of Tropical Medicine and Hygiene |
| dc.publisher.group.spa.fl_str_mv |
Programa de Estudio y Control de Enfermedades Tropicales (PECET) |
| dc.publisher.place.spa.fl_str_mv |
Baltimore, Estados Unidos |
| institution |
Universidad de Antioquia |
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https://bibliotecadigital.udea.edu.co/bitstream/10495/32117/1/Velez_Dario_2009_LeishmaniasisEpidemicAmhara.pdf https://bibliotecadigital.udea.edu.co/bitstream/10495/32117/2/license_rdf https://bibliotecadigital.udea.edu.co/bitstream/10495/32117/3/license.txt |
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Repositorio Institucional Universidad de Antioquia |
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andres.perez@udea.edu.co |
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Vélez Bernal, Iván DaríoBashaye, SeifeNombela, NohellyArgaw, DanielMulugeta, AbateHerrero, MerceNieto, JavierChicharro, CarmenCañavate, CarmenAparicio, PilarAlvar, JorgeBern, Caryn2022-11-17T18:40:07Z2022-11-17T18:40:07Z2009Bashaye S, Nombela N, Argaw D, Mulugeta A, Herrero M, Nieto J, Chicharro C, Cañavate C, Aparicio P, Vélez ID, Alvar J, Bern C. Risk factors for visceral leishmaniasis in a new epidemic site in Amhara Region, Ethiopia. Am J Trop Med Hyg. 2009 Jul;81(1):34-9.0002-9637https://hdl.handle.net/10495/3211710.4269/ajtmh.2009.81.341476-1645ABSTRACT: We conducted a case-control study to evaluate risk factors for visceral leishmaniasis during an epidemic in a previously unaffected district of Ethiopia. We also collected blood and bone marrow specimens from dogs in the outbreak villages. In multivariable analyses of 171 matched case-control pairs, dog ownership, sleeping under an acacia tree during the day, and habitually sleeping outside at night were associated with significantly increased risk. Specimens from 7 (3.8%) dogs were positive by immunofluorescent antibody test (IFAT) and both enzyme-linked immunosorbent assays (ELISAs), whereas Leishmania DNA was detected in 5 (2.8%) bone marrow aspirates (from 3 seropositive and 2 seronegative dogs). Insecticide-treated nets may only protect a portion of those at risk. Further research on the vectors, the role of the dog in the transmission cycle, and the effect of candidate interventions are needed to design the best strategy for control.COL00150996application/pdfengAmerican Society of Tropical Medicine and HygienePrograma de Estudio y Control de Enfermedades Tropicales (PECET)Baltimore, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Risk factors for visceral leishmaniasis in a new epidemic site in Amhara region, EthiopiaLeishmaniasis VisceralLeishmaniasis, VisceralEnfermedades de los PerrosDog DiseasesEtiopíaEthiopiaPreescolarChild, PreschoolEstudios de Casos y ControlesCase-Control StudiesAm. J. Trop. Med. Hyg.American Journal of Tropical Medicine and Hygiene3439811ORIGINALVelez_Dario_2009_LeishmaniasisEpidemicAmhara.pdfVelez_Dario_2009_LeishmaniasisEpidemicAmhara.pdfArtículo de investigaciónapplication/pdf456821https://bibliotecadigital.udea.edu.co/bitstream/10495/32117/1/Velez_Dario_2009_LeishmaniasisEpidemicAmhara.pdf0c1a8f70d8c8f69711c1a1af20ca638eMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927https://bibliotecadigital.udea.edu.co/bitstream/10495/32117/2/license_rdf1646d1f6b96dbbbc38035efc9239ac9cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/32117/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/32117oai:bibliotecadigital.udea.edu.co:10495/321172022-11-17 13:40:08.497Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |