Evaluación de la terapia con linfocitos alogénicos de sangre periférica en lechones precebos sobre sus parámetros productivos durante la ceba

ABSTRACT: Finishing pigs with a health condition during the fattening period and at slaughter could be considered resistant or immunocompetent against the pathogens of the farm. In order to evaluate the potential of peripheral blood mononuclear cells (PBMC) from these animals to confer immunological resistence to growing piglets of the same farm, 200 weaned piglets were selected in a commercial farm and randomly assigned to receive treatment with: Group 1, two sc. immunizations within a 15 days interval with 1 ml (5 x 107 cells/ml) of pooled PBM isolated from finishing pigs that did not have clinical evidence of digestive or respiratory diseases prior to slaughtering (n = 100) ; and group 2, inoculation with 1 ml saline (SSF) under the same schedule (n = 100). Both respiratory and digestive- associated morbidity and mortality cases, average daily gain (ADG) and total weight gain (TWG) during the fattening period were recorded. Serum samples were taken 15 days after inoculation and evaluated by serology for leptospira, brucella, and parvovirus. Data were analyzed by Anova and Fisher exact test. No statistically significant differences for ADG no for TWG were observed between groups (p > 0.05). No cases of morbidity or mortality were observed during the study. These results suggest that allogenic peripheral blood mononuclear cell do not have an effect on economic traits in fattening pigs, in concordance with similar results found with lymph node mononuclear cells. However because of the lack of morbidity rates in the study, conclusions could not be made on the effects of PBM on morbidity and mortality rates during the fattening period.

• Autores: Higuita M, Diego; Tobón, Juan Carlos; Peláez, Jhon Carlos; Maldonado Estrada, Juan Guillermo
• Tipo de recurso: Article of investigation
• Fecha de publicación: 1999
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: spa
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/6825
• Acceso en línea: http://hdl.handle.net/10495/6825
• Palabra clave: Respuesta inmune; Pigs; Porcinos; Lechones
• Rights: openAccess
• License: Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)