Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
ABSTRACT: Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied...
- Autores:
-
Zapata Vahos, Isabel Cristina
Ochoa, Susana
Maldonado Celis, María Elena
Zapata Zapata, Arley David
Rojano, Benjamín Alberto
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/11707
- Acceso en línea:
- http://hdl.handle.net/10495/11707
- Palabra clave:
- Fermented beverage
Andean berry
Antioxidant activity
Antiproliferative activity
Alcoholic beverage
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 2.5 Colombia
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dc.title.spa.fl_str_mv |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
title |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
spellingShingle |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine Fermented beverage Andean berry Antioxidant activity Antiproliferative activity Alcoholic beverage |
title_short |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
title_full |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
title_fullStr |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
title_full_unstemmed |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
title_sort |
Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine |
dc.creator.fl_str_mv |
Zapata Vahos, Isabel Cristina Ochoa, Susana Maldonado Celis, María Elena Zapata Zapata, Arley David Rojano, Benjamín Alberto |
dc.contributor.author.none.fl_str_mv |
Zapata Vahos, Isabel Cristina Ochoa, Susana Maldonado Celis, María Elena Zapata Zapata, Arley David Rojano, Benjamín Alberto |
dc.subject.none.fl_str_mv |
Fermented beverage Andean berry Antioxidant activity Antiproliferative activity Alcoholic beverage |
topic |
Fermented beverage Andean berry Antioxidant activity Antiproliferative activity Alcoholic beverage |
description |
ABSTRACT: Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied for their composition and health benefits. By this, the aim of this research was to obtain three types of alcoholic beverages from Andean berry, which have different treatments. The methods used to obtain the beverages were macerated fruit machine (MAC), preheating of the fruit (CAL) and by combining both of them (MIX). The antioxidant activity was evaluated by FRAP, DPPH, ORAC methods and anthocyanins and total phenols were measured. Finally, the antiproliferative effect was evaluated on a colon cancer cell line (SW480). Findings suggest that ethanol content of final products is not altered by treatment of unfermented Andean berry juice (must). The alcohol concentrations for MAC, CAL and MIX drinks were 90±1.7, 89±3.6 and 94±4.1 g/L, respectively. The results showed that CAL and MIX methods favor the extraction of secondary metabolites and consequently increase the antioxidant activity. The fermentation process affected the antioxidant power and total phenolic content in beverages CAL and MIX. However, no significant changes in these parameters were observed in the MAC drink. These beverages can eventually reduce the cancer cell viability between 15.1 (20 μg/L) and 37.2% (200 μg/mL). Thus, it was concluded that MIX treatment has higher antioxidant power and it could reduce the cancer cell viability. |
publishDate |
2016 |
dc.date.issued.none.fl_str_mv |
2016 |
dc.date.accessioned.none.fl_str_mv |
2019-08-22T14:02:24Z |
dc.date.available.none.fl_str_mv |
2019-08-22T14:02:24Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
dc.type.local.spa.fl_str_mv |
Artículo de investigación |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
status_str |
publishedVersion |
dc.identifier.citation.spa.fl_str_mv |
Zapata-Vahos I, Ochoa S, Maldonado-Celis M, Zapata-Zapata A, Rojano B. Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine. J. Med. Plants. Res.. 2016; 10(27): 402-8. DOI: 10.5897/JMPR2016.6100 |
dc.identifier.issn.none.fl_str_mv |
1996-0875 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/11707 |
identifier_str_mv |
Zapata-Vahos I, Ochoa S, Maldonado-Celis M, Zapata-Zapata A, Rojano B. Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine. J. Med. Plants. Res.. 2016; 10(27): 402-8. DOI: 10.5897/JMPR2016.6100 1996-0875 |
url |
http://hdl.handle.net/10495/11707 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
J. Med. Plants. Res. |
dc.rights.*.fl_str_mv |
Atribución-NoComercial-SinDerivadas 2.5 Colombia |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
rights_invalid_str_mv |
Atribución-NoComercial-SinDerivadas 2.5 Colombia http://creativecommons.org/licenses/by-nc-nd/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Academic Journals |
dc.publisher.group.spa.fl_str_mv |
Impacto de Componentes Alimentarios en la Salud |
dc.publisher.place.spa.fl_str_mv |
Nigeria |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/1/ZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdf http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/2/license.txt |
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MD5 MD5 |
repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
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1812173168354263040 |
spelling |
Zapata Vahos, Isabel CristinaOchoa, SusanaMaldonado Celis, María ElenaZapata Zapata, Arley DavidRojano, Benjamín Alberto2019-08-22T14:02:24Z2019-08-22T14:02:24Z2016Zapata-Vahos I, Ochoa S, Maldonado-Celis M, Zapata-Zapata A, Rojano B. Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine. J. Med. Plants. Res.. 2016; 10(27): 402-8. DOI: 10.5897/JMPR2016.61001996-0875http://hdl.handle.net/10495/11707ABSTRACT: Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied for their composition and health benefits. By this, the aim of this research was to obtain three types of alcoholic beverages from Andean berry, which have different treatments. The methods used to obtain the beverages were macerated fruit machine (MAC), preheating of the fruit (CAL) and by combining both of them (MIX). The antioxidant activity was evaluated by FRAP, DPPH, ORAC methods and anthocyanins and total phenols were measured. Finally, the antiproliferative effect was evaluated on a colon cancer cell line (SW480). Findings suggest that ethanol content of final products is not altered by treatment of unfermented Andean berry juice (must). The alcohol concentrations for MAC, CAL and MIX drinks were 90±1.7, 89±3.6 and 94±4.1 g/L, respectively. The results showed that CAL and MIX methods favor the extraction of secondary metabolites and consequently increase the antioxidant activity. The fermentation process affected the antioxidant power and total phenolic content in beverages CAL and MIX. However, no significant changes in these parameters were observed in the MAC drink. These beverages can eventually reduce the cancer cell viability between 15.1 (20 μg/L) and 37.2% (200 μg/mL). Thus, it was concluded that MIX treatment has higher antioxidant power and it could reduce the cancer cell viability.application/pdfengAcademic JournalsImpacto de Componentes Alimentarios en la SaludNigeriainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-SinDerivadas 2.5 Colombiainfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/Fermented beverageAndean berryAntioxidant activityAntiproliferative activityAlcoholic beverageCytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wineJ. Med. Plants. Res.Journal of Medicinal Plants Research4024081027ORIGINALZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdfZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdfArtículo de investigaciónapplication/pdf502780http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/1/ZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdfd4abe5583c4ee6ef3c5b157adef115beMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5210495/11707oai:bibliotecadigital.udea.edu.co:10495/117072021-10-25 13:38:18.052Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |