Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine

ABSTRACT: Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied...

Full description

Autores:
Zapata Vahos, Isabel Cristina
Ochoa, Susana
Maldonado Celis, María Elena
Zapata Zapata, Arley David
Rojano, Benjamín Alberto
Tipo de recurso:
Article of investigation
Fecha de publicación:
2016
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/11707
Acceso en línea:
http://hdl.handle.net/10495/11707
Palabra clave:
Fermented beverage
Andean berry
Antioxidant activity
Antiproliferative activity
Alcoholic beverage
Rights
openAccess
License
Atribución-NoComercial-SinDerivadas 2.5 Colombia
id UDEA2_4b233ec4e63e3a85d2691a8456a3a977
oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/11707
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
title Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
spellingShingle Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
Fermented beverage
Andean berry
Antioxidant activity
Antiproliferative activity
Alcoholic beverage
title_short Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
title_full Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
title_fullStr Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
title_full_unstemmed Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
title_sort Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine
dc.creator.fl_str_mv Zapata Vahos, Isabel Cristina
Ochoa, Susana
Maldonado Celis, María Elena
Zapata Zapata, Arley David
Rojano, Benjamín Alberto
dc.contributor.author.none.fl_str_mv Zapata Vahos, Isabel Cristina
Ochoa, Susana
Maldonado Celis, María Elena
Zapata Zapata, Arley David
Rojano, Benjamín Alberto
dc.subject.none.fl_str_mv Fermented beverage
Andean berry
Antioxidant activity
Antiproliferative activity
Alcoholic beverage
topic Fermented beverage
Andean berry
Antioxidant activity
Antiproliferative activity
Alcoholic beverage
description ABSTRACT: Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied for their composition and health benefits. By this, the aim of this research was to obtain three types of alcoholic beverages from Andean berry, which have different treatments. The methods used to obtain the beverages were macerated fruit machine (MAC), preheating of the fruit (CAL) and by combining both of them (MIX). The antioxidant activity was evaluated by FRAP, DPPH, ORAC methods and anthocyanins and total phenols were measured. Finally, the antiproliferative effect was evaluated on a colon cancer cell line (SW480). Findings suggest that ethanol content of final products is not altered by treatment of unfermented Andean berry juice (must). The alcohol concentrations for MAC, CAL and MIX drinks were 90±1.7, 89±3.6 and 94±4.1 g/L, respectively. The results showed that CAL and MIX methods favor the extraction of secondary metabolites and consequently increase the antioxidant activity. The fermentation process affected the antioxidant power and total phenolic content in beverages CAL and MIX. However, no significant changes in these parameters were observed in the MAC drink. These beverages can eventually reduce the cancer cell viability between 15.1 (20 μg/L) and 37.2% (200 μg/mL). Thus, it was concluded that MIX treatment has higher antioxidant power and it could reduce the cancer cell viability.
publishDate 2016
dc.date.issued.none.fl_str_mv 2016
dc.date.accessioned.none.fl_str_mv 2019-08-22T14:02:24Z
dc.date.available.none.fl_str_mv 2019-08-22T14:02:24Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/ART
dc.type.local.spa.fl_str_mv Artículo de investigación
format http://purl.org/coar/resource_type/c_2df8fbb1
status_str publishedVersion
dc.identifier.citation.spa.fl_str_mv Zapata-Vahos I, Ochoa S, Maldonado-Celis M, Zapata-Zapata A, Rojano B. Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine. J. Med. Plants. Res.. 2016; 10(27): 402-8. DOI: 10.5897/JMPR2016.6100
dc.identifier.issn.none.fl_str_mv 1996-0875
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/11707
identifier_str_mv Zapata-Vahos I, Ochoa S, Maldonado-Celis M, Zapata-Zapata A, Rojano B. Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine. J. Med. Plants. Res.. 2016; 10(27): 402-8. DOI: 10.5897/JMPR2016.6100
1996-0875
url http://hdl.handle.net/10495/11707
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv J. Med. Plants. Res.
dc.rights.*.fl_str_mv Atribución-NoComercial-SinDerivadas 2.5 Colombia
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.rights.accessrights.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.creativecommons.spa.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
rights_invalid_str_mv Atribución-NoComercial-SinDerivadas 2.5 Colombia
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Academic Journals
dc.publisher.group.spa.fl_str_mv Impacto de Componentes Alimentarios en la Salud
dc.publisher.place.spa.fl_str_mv Nigeria
institution Universidad de Antioquia
bitstream.url.fl_str_mv http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/1/ZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdf
http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/2/license.txt
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repository.name.fl_str_mv Repositorio Institucional Universidad de Antioquia
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spelling Zapata Vahos, Isabel CristinaOchoa, SusanaMaldonado Celis, María ElenaZapata Zapata, Arley DavidRojano, Benjamín Alberto2019-08-22T14:02:24Z2019-08-22T14:02:24Z2016Zapata-Vahos I, Ochoa S, Maldonado-Celis M, Zapata-Zapata A, Rojano B. Cytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wine. J. Med. Plants. Res.. 2016; 10(27): 402-8. DOI: 10.5897/JMPR2016.61001996-0875http://hdl.handle.net/10495/11707ABSTRACT: Vaccinium meridonale Sw or Andean berry has antioxidant properties due to its high content of polyphenols, as anthocyanins and phenolic acids. Polyphenols have been associated with the prevention of chronic and cardiovascular diseases. In the last years, alcoholic drinks have been studied for their composition and health benefits. By this, the aim of this research was to obtain three types of alcoholic beverages from Andean berry, which have different treatments. The methods used to obtain the beverages were macerated fruit machine (MAC), preheating of the fruit (CAL) and by combining both of them (MIX). The antioxidant activity was evaluated by FRAP, DPPH, ORAC methods and anthocyanins and total phenols were measured. Finally, the antiproliferative effect was evaluated on a colon cancer cell line (SW480). Findings suggest that ethanol content of final products is not altered by treatment of unfermented Andean berry juice (must). The alcohol concentrations for MAC, CAL and MIX drinks were 90±1.7, 89±3.6 and 94±4.1 g/L, respectively. The results showed that CAL and MIX methods favor the extraction of secondary metabolites and consequently increase the antioxidant activity. The fermentation process affected the antioxidant power and total phenolic content in beverages CAL and MIX. However, no significant changes in these parameters were observed in the MAC drink. These beverages can eventually reduce the cancer cell viability between 15.1 (20 μg/L) and 37.2% (200 μg/mL). Thus, it was concluded that MIX treatment has higher antioxidant power and it could reduce the cancer cell viability.application/pdfengAcademic JournalsImpacto de Componentes Alimentarios en la SaludNigeriainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-SinDerivadas 2.5 Colombiainfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/Fermented beverageAndean berryAntioxidant activityAntiproliferative activityAlcoholic beverageCytotoxic effect and antioxidant activity of Andean berry (Vaccinium meridionale Sw) wineJ. Med. Plants. Res.Journal of Medicinal Plants Research4024081027ORIGINALZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdfZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdfArtículo de investigaciónapplication/pdf502780http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/1/ZapataIsabel_2016_CytotoxicEffectAntioxidantActivity.pdfd4abe5583c4ee6ef3c5b157adef115beMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/11707/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5210495/11707oai:bibliotecadigital.udea.edu.co:10495/117072021-10-25 13:38:18.052Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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