Does the time of isolation need to be re-evaluated in prisoners with tuberculosis?
ABSTRACT: Background: According to WHO, CDC, IDSA and ATS guidelines, patients with pulmonary tuberculosis (Tb) can be considered as non infectious when: 1) they are receiving multiple drugs for 2 to 3 weeks; 2) there is an improvement in clinical condition; 3) the likelihood of MDR-Tb is very small...
- Autores:
-
Vélez Giraldo, Lázaro Agustín
López López, Lucelly
Rueda Vallejo, Zulma Vanessa
Giraldo, Margarita Rosa
Marín Pineda, Diana Marcela
Zapata, Elsa
Mejía Mesa, Gloria Isabel
Robledo, Jaime
Arbeláez Montoya, María Patricia
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2012
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/32010
- Acceso en línea:
- https://hdl.handle.net/10495/32010
- Palabra clave:
- Tuberculosis Pulmonar
Tuberculosis, Pulmonary
Aislamiento de Pacientes
Patient Isolation
Prisioneros
Prisoners
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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|
dc.title.spa.fl_str_mv |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
title |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
spellingShingle |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? Tuberculosis Pulmonar Tuberculosis, Pulmonary Aislamiento de Pacientes Patient Isolation Prisioneros Prisoners |
title_short |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
title_full |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
title_fullStr |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
title_full_unstemmed |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
title_sort |
Does the time of isolation need to be re-evaluated in prisoners with tuberculosis? |
dc.creator.fl_str_mv |
Vélez Giraldo, Lázaro Agustín López López, Lucelly Rueda Vallejo, Zulma Vanessa Giraldo, Margarita Rosa Marín Pineda, Diana Marcela Zapata, Elsa Mejía Mesa, Gloria Isabel Robledo, Jaime Arbeláez Montoya, María Patricia |
dc.contributor.author.none.fl_str_mv |
Vélez Giraldo, Lázaro Agustín López López, Lucelly Rueda Vallejo, Zulma Vanessa Giraldo, Margarita Rosa Marín Pineda, Diana Marcela Zapata, Elsa Mejía Mesa, Gloria Isabel Robledo, Jaime Arbeláez Montoya, María Patricia |
dc.subject.decs.none.fl_str_mv |
Tuberculosis Pulmonar Tuberculosis, Pulmonary Aislamiento de Pacientes Patient Isolation Prisioneros Prisoners |
topic |
Tuberculosis Pulmonar Tuberculosis, Pulmonary Aislamiento de Pacientes Patient Isolation Prisioneros Prisoners |
description |
ABSTRACT: Background: According to WHO, CDC, IDSA and ATS guidelines, patients with pulmonary tuberculosis (Tb) can be considered as non infectious when: 1) they are receiving multiple drugs for 2 to 3 weeks; 2) there is an improvement in clinical condition; 3) the likelihood of MDR-Tb is very small. Objective: To determine the time for sputum reversion since the start of anti-Tb treatment in prisoners from four jails in Medellin and Bucaramanga, Colombia between May 2010 to April 2011. Methods: Prospective cohort study. All prisoners diagnosed with Tb by sputum smear or culture were followed for two years: monthly for the first six months after the start of treatment, bimonthly the next six months, and quarterly the second year. During follow-up, we took two spontaneous and one induced sputum samples for auramine-rodhamine stain, and cultures in thin layer agar, Löwestein-Jensen and MGIT for the both first samples. We did time to event analysis. Results: We could follow 45 of 47 positive patients (one was transferred to another jail and one Tb-related death). The median for sputum smear reversion was 33 days (IQR: 31-60), and for culture was 55 days (IQR: 32-68). 90% of the patients had sputum smear and culture negative at 102 days. The time for sputum to become negative by culture had a positive correlation with the sputum grade at the moment of diagnosis: negative smear with positive culture= median 31.5 days, smear with 1+ = 58.5 days, smear 2+ = 62 days, and smear 3+ = 65 days (p value = 0.007). Conclusion: After starting treatment the reversion of cultures took two or more months in ≥50% cases. That is forcing us to rethink the recommendations about the isolation of patients with pulmonary Tb in prisons, and suggests the need to use mycobacterial cultures on sputum to follow-up those patients. |
publishDate |
2012 |
dc.date.issued.none.fl_str_mv |
2012 |
dc.date.accessioned.none.fl_str_mv |
2022-11-13T18:06:24Z |
dc.date.available.none.fl_str_mv |
2022-11-13T18:06:24Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/CJournalArticle |
dc.type.local.spa.fl_str_mv |
Artículo de revista |
format |
http://purl.org/coar/resource_type/c_6501 |
status_str |
publishedVersion |
dc.identifier.issn.none.fl_str_mv |
1201-9712 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/32010 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.ijid.2012.05.956 |
identifier_str_mv |
1201-9712 10.1016/j.ijid.2012.05.956 |
url |
https://hdl.handle.net/10495/32010 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Int. J. Infect. Dis. |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.format.extent.spa.fl_str_mv |
1 |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Elsevier International Society for Infectious Diseases |
dc.publisher.group.spa.fl_str_mv |
GRIPE: Grupo Investigador de Problemas en Enfermedades Infecciosas |
dc.publisher.place.spa.fl_str_mv |
Hamilton, Canadá |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstream/10495/32010/1/VelezLazaro_2012_IsolationReevaluatedTuberculosis.pdf https://bibliotecadigital.udea.edu.co/bitstream/10495/32010/2/license_rdf https://bibliotecadigital.udea.edu.co/bitstream/10495/32010/3/license.txt |
bitstream.checksum.fl_str_mv |
7504a3b6faac6e0a6ea6f6166fbbad3a b88b088d9957e670ce3b3fbe2eedbc13 8a4605be74aa9ea9d79846c1fba20a33 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
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1812173118233378816 |
spelling |
Vélez Giraldo, Lázaro AgustínLópez López, LucellyRueda Vallejo, Zulma VanessaGiraldo, Margarita RosaMarín Pineda, Diana MarcelaZapata, ElsaMejía Mesa, Gloria IsabelRobledo, JaimeArbeláez Montoya, María Patricia2022-11-13T18:06:24Z2022-11-13T18:06:24Z20121201-9712https://hdl.handle.net/10495/3201010.1016/j.ijid.2012.05.956ABSTRACT: Background: According to WHO, CDC, IDSA and ATS guidelines, patients with pulmonary tuberculosis (Tb) can be considered as non infectious when: 1) they are receiving multiple drugs for 2 to 3 weeks; 2) there is an improvement in clinical condition; 3) the likelihood of MDR-Tb is very small. Objective: To determine the time for sputum reversion since the start of anti-Tb treatment in prisoners from four jails in Medellin and Bucaramanga, Colombia between May 2010 to April 2011. Methods: Prospective cohort study. All prisoners diagnosed with Tb by sputum smear or culture were followed for two years: monthly for the first six months after the start of treatment, bimonthly the next six months, and quarterly the second year. During follow-up, we took two spontaneous and one induced sputum samples for auramine-rodhamine stain, and cultures in thin layer agar, Löwestein-Jensen and MGIT for the both first samples. We did time to event analysis. Results: We could follow 45 of 47 positive patients (one was transferred to another jail and one Tb-related death). The median for sputum smear reversion was 33 days (IQR: 31-60), and for culture was 55 days (IQR: 32-68). 90% of the patients had sputum smear and culture negative at 102 days. The time for sputum to become negative by culture had a positive correlation with the sputum grade at the moment of diagnosis: negative smear with positive culture= median 31.5 days, smear with 1+ = 58.5 days, smear 2+ = 62 days, and smear 3+ = 65 days (p value = 0.007). Conclusion: After starting treatment the reversion of cultures took two or more months in ≥50% cases. That is forcing us to rethink the recommendations about the isolation of patients with pulmonary Tb in prisons, and suggests the need to use mycobacterial cultures on sputum to follow-up those patients.COL00057441application/pdfengElsevierInternational Society for Infectious DiseasesGRIPE: Grupo Investigador de Problemas en Enfermedades InfecciosasHamilton, Canadáinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/redcol/resource_type/CJournalArticleArtículo de revistahttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/Does the time of isolation need to be re-evaluated in prisoners with tuberculosis?Tuberculosis PulmonarTuberculosis, PulmonaryAislamiento de PacientesPatient IsolationPrisionerosPrisonersInt. J. Infect. Dis.International Journal of Infectious Diseasese286e28616ORIGINALVelezLazaro_2012_IsolationReevaluatedTuberculosis.pdfVelezLazaro_2012_IsolationReevaluatedTuberculosis.pdfArtículo de revistaapplication/pdf86659https://bibliotecadigital.udea.edu.co/bitstream/10495/32010/1/VelezLazaro_2012_IsolationReevaluatedTuberculosis.pdf7504a3b6faac6e0a6ea6f6166fbbad3aMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8823https://bibliotecadigital.udea.edu.co/bitstream/10495/32010/2/license_rdfb88b088d9957e670ce3b3fbe2eedbc13MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/32010/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/32010oai:bibliotecadigital.udea.edu.co:10495/320102022-11-13 13:06:24.548Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |