Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox
ABSTARCT: Three new triterpene glycosides, named ulososide F (1), urabosides A (2) and B (3), together with the previously reported ulososide A (4), were isolated from the Caribbean marine sponge Ectyoplasia ferox. Their structures were elucidated using extensive interpretation of 1D and 2D-NMR data...
- Autores:
-
Colorado Ríos, Jhonny
Muñoz Lasso, Diana Carolina
Márquez Fernández, Diana Margarita
López Ortíz, Juan Bautista
Thomas, Oliver P.
Martínez Martínez, Alejandro
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2013
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/8524
- Acceso en línea:
- http://hdl.handle.net/10495/8524
- Palabra clave:
- Saponinas
saponins
Esponjas
sponges
Esponja marina
Ectyoplasia ferox
Ulososidos
Urabósidos
http://aims.fao.org/aos/agrovoc/c_6795
http://aims.fao.org/aos/agrovoc/c_7321
- Rights
- openAccess
- License
- Atribución 2.5 Colombia (CC BY 2.5 CO)
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|
| dc.title.spa.fl_str_mv |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| title |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| spellingShingle |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox Saponinas saponins Esponjas sponges Esponja marina Ectyoplasia ferox Ulososidos Urabósidos http://aims.fao.org/aos/agrovoc/c_6795 http://aims.fao.org/aos/agrovoc/c_7321 |
| title_short |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| title_full |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| title_fullStr |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| title_full_unstemmed |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| title_sort |
Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox |
| dc.creator.fl_str_mv |
Colorado Ríos, Jhonny Muñoz Lasso, Diana Carolina Márquez Fernández, Diana Margarita López Ortíz, Juan Bautista Thomas, Oliver P. Martínez Martínez, Alejandro |
| dc.contributor.author.none.fl_str_mv |
Colorado Ríos, Jhonny Muñoz Lasso, Diana Carolina Márquez Fernández, Diana Margarita López Ortíz, Juan Bautista Thomas, Oliver P. Martínez Martínez, Alejandro |
| dc.subject.agrovoc.none.fl_str_mv |
Saponinas saponins Esponjas sponges |
| topic |
Saponinas saponins Esponjas sponges Esponja marina Ectyoplasia ferox Ulososidos Urabósidos http://aims.fao.org/aos/agrovoc/c_6795 http://aims.fao.org/aos/agrovoc/c_7321 |
| dc.subject.proposal.spa.fl_str_mv |
Esponja marina Ectyoplasia ferox Ulososidos Urabósidos |
| dc.subject.unescouri.none.fl_str_mv |
http://aims.fao.org/aos/agrovoc/c_6795 http://aims.fao.org/aos/agrovoc/c_7321 |
| description |
ABSTARCT: Three new triterpene glycosides, named ulososide F (1), urabosides A (2) and B (3), together with the previously reported ulososide A (4), were isolated from the Caribbean marine sponge Ectyoplasia ferox. Their structures were elucidated using extensive interpretation of 1D and 2D-NMR data, as well as HRESIMS. The aglycon of all compounds is a rare 30-norlonastane and the sugar residues were identified after acid hydrolysis and GC analyses. Cytotoxicities of the isolated compounds were evaluated against Jurkat and CHO cell lines by a MTT in vitro assay as well as a hemolysis assay. Unexpectedly, all these saponin derivatives showed very low activity in our bioassays. |
| publishDate |
2013 |
| dc.date.issued.none.fl_str_mv |
2013 |
| dc.date.accessioned.none.fl_str_mv |
2017-10-10T19:23:54Z |
| dc.date.available.none.fl_str_mv |
2017-10-10T19:23:54Z |
| dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a86 http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
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Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.identifier.citation.spa.fl_str_mv |
J. Colorado-Ríos, D. C. Muñoz-Lasso, D. M. Márquez-Fernández, M. E. Márquez-Fernández, J. B. López Ortíz, O. P. Thomas and A. Martínez-Martínez, "Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox," molecules, vol. 18, pp. 2598-2610, 2013. |
| dc.identifier.issn.none.fl_str_mv |
1420-3049 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/8524 |
| dc.identifier.doi.none.fl_str_mv |
10.3390/molecules18032598 |
| identifier_str_mv |
J. Colorado-Ríos, D. C. Muñoz-Lasso, D. M. Márquez-Fernández, M. E. Márquez-Fernández, J. B. López Ortíz, O. P. Thomas and A. Martínez-Martínez, "Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox," molecules, vol. 18, pp. 2598-2610, 2013. 1420-3049 10.3390/molecules18032598 |
| url |
http://hdl.handle.net/10495/8524 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Molecules |
| dc.rights.*.fl_str_mv |
Atribución 2.5 Colombia (CC BY 2.5 CO) |
| dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/2.5/co/ |
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https://creativecommons.org/licenses/by/4.0/ |
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Atribución 2.5 Colombia (CC BY 2.5 CO) https://creativecommons.org/licenses/by/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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12 |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
MDPI |
| dc.publisher.group.spa.fl_str_mv |
Productos Naturales Marinos |
| dc.publisher.place.spa.fl_str_mv |
Suiza |
| institution |
Universidad de Antioquia |
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Colorado Ríos, JhonnyMuñoz Lasso, Diana CarolinaMárquez Fernández, Diana MargaritaLópez Ortíz, Juan BautistaThomas, Oliver P.Martínez Martínez, Alejandro2017-10-10T19:23:54Z2017-10-10T19:23:54Z2013J. Colorado-Ríos, D. C. Muñoz-Lasso, D. M. Márquez-Fernández, M. E. Márquez-Fernández, J. B. López Ortíz, O. P. Thomas and A. Martínez-Martínez, "Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox," molecules, vol. 18, pp. 2598-2610, 2013.1420-3049http://hdl.handle.net/10495/852410.3390/molecules18032598ABSTARCT: Three new triterpene glycosides, named ulososide F (1), urabosides A (2) and B (3), together with the previously reported ulososide A (4), were isolated from the Caribbean marine sponge Ectyoplasia ferox. Their structures were elucidated using extensive interpretation of 1D and 2D-NMR data, as well as HRESIMS. The aglycon of all compounds is a rare 30-norlonastane and the sugar residues were identified after acid hydrolysis and GC analyses. Cytotoxicities of the isolated compounds were evaluated against Jurkat and CHO cell lines by a MTT in vitro assay as well as a hemolysis assay. Unexpectedly, all these saponin derivatives showed very low activity in our bioassays.12application/pdfengMDPIProductos Naturales MarinosSuizainfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a86http://purl.org/coar/version/c_970fb48d4fbd8a85Atribución 2.5 Colombia (CC BY 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia feroxSaponinassaponinsEsponjasspongesEsponja marinaEctyoplasia feroxUlososidosUrabósidoshttp://aims.fao.org/aos/agrovoc/c_6795http://aims.fao.org/aos/agrovoc/c_7321MoleculesMolecules2598261018CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://bibliotecadigital.udea.edu.co/bitstream/10495/8524/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/8524/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfLicenciaapplication/rdf+xml; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/8524/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/8524/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD55ORIGINALMartinezAlejandro_2013_UlososidesUrabosidesTriterpenoid.pdfMartinezAlejandro_2013_UlososidesUrabosidesTriterpenoid.pdfArtículo de investigaciónapplication/pdf273010http://bibliotecadigital.udea.edu.co/bitstream/10495/8524/1/MartinezAlejandro_2013_UlososidesUrabosidesTriterpenoid.pdf5c6443111fe293a1e663fa539bb40f70MD5110495/8524oai:bibliotecadigital.udea.edu.co:10495/85242021-04-29 19:54:23.458Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |