Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy
ABSTRACT: We describe the case of a diabetic patient who developed a severe invasive fungal infection due to Rhizopus species postoperatively after a dual heart/kidney transplantation with subsequent intensive immunosuppressive therapy. No improvement was noted with amphotericin B (deoxycholate) the...
- Autores:
-
Tobón Orozco, Ángela María
Arango Arteaga, Myrtha
Fernández, Darío
Restrepo Moreno, Ángela
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2003
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/24085
- Acceso en línea:
- http://hdl.handle.net/10495/24085
- Palabra clave:
- Diabetes mellitus
Trasplante de Riñón
Kidney Transplantation
Zigomicosis
Zygomycosis
Anfotericina B
Amphotericin B
Mucormicosis
Mucormycosis
Rhizopus
Ácido Desoxicólico
Deoxycholic Acid
Receptores de Trasplantes
Transplant Recipients
Riñón
Kidney
Corazón
Heart
Inmunosupresión
Inmunosuppression
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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|
| dc.title.spa.fl_str_mv |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| title |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| spellingShingle |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy Diabetes mellitus Trasplante de Riñón Kidney Transplantation Zigomicosis Zygomycosis Anfotericina B Amphotericin B Mucormicosis Mucormycosis Rhizopus Ácido Desoxicólico Deoxycholic Acid Receptores de Trasplantes Transplant Recipients Riñón Kidney Corazón Heart Inmunosupresión Inmunosuppression |
| title_short |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| title_full |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| title_fullStr |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| title_full_unstemmed |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| title_sort |
Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapy |
| dc.creator.fl_str_mv |
Tobón Orozco, Ángela María Arango Arteaga, Myrtha Fernández, Darío Restrepo Moreno, Ángela |
| dc.contributor.author.none.fl_str_mv |
Tobón Orozco, Ángela María Arango Arteaga, Myrtha Fernández, Darío Restrepo Moreno, Ángela |
| dc.subject.decs.none.fl_str_mv |
Diabetes mellitus Trasplante de Riñón Kidney Transplantation Zigomicosis Zygomycosis Anfotericina B Amphotericin B Mucormicosis Mucormycosis Rhizopus Ácido Desoxicólico Deoxycholic Acid Receptores de Trasplantes Transplant Recipients Riñón Kidney Corazón Heart |
| topic |
Diabetes mellitus Trasplante de Riñón Kidney Transplantation Zigomicosis Zygomycosis Anfotericina B Amphotericin B Mucormicosis Mucormycosis Rhizopus Ácido Desoxicólico Deoxycholic Acid Receptores de Trasplantes Transplant Recipients Riñón Kidney Corazón Heart Inmunosupresión Inmunosuppression |
| dc.subject.lemb.none.fl_str_mv |
Inmunosupresión Inmunosuppression |
| description |
ABSTRACT: We describe the case of a diabetic patient who developed a severe invasive fungal infection due to Rhizopus species postoperatively after a dual heart/kidney transplantation with subsequent intensive immunosuppressive therapy. No improvement was noted with amphotericin B (deoxycholate) therapy, but salvage treatment with the new azole antifungal posaconazole (200 mg orally 4 times daily) resulted in dramatic clinical improvement as early as 1 week after the initiation of therapy that continued through 23 weeks of treatment, with marked clinical, mycological, and radiological improvements and no adverse events. |
| publishDate |
2003 |
| dc.date.issued.none.fl_str_mv |
2003 |
| dc.date.accessioned.none.fl_str_mv |
2021-11-14T12:15:16Z |
| dc.date.available.none.fl_str_mv |
2021-11-14T12:15:16Z |
| dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_6501 |
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https://purl.org/redcol/resource_type/ARTCASO |
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Reporte de caso |
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http://purl.org/coar/resource_type/c_6501 |
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publishedVersion |
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1058-4838 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/24085 |
| dc.identifier.doi.none.fl_str_mv |
10.1086/375075 |
| dc.identifier.eissn.none.fl_str_mv |
1537-6591 |
| identifier_str_mv |
1058-4838 10.1086/375075 1537-6591 |
| url |
http://hdl.handle.net/10495/24085 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Clin. Infect. Dis. |
| dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
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http://purl.org/coar/access_right/c_abf2 |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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http://creativecommons.org/licenses/by-nc-nd/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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4 |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
University of Chicago Press |
| dc.publisher.group.spa.fl_str_mv |
Micología Médica y Experimental |
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Chicago, Estados Unidos |
| institution |
Universidad de Antioquia |
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andres.perez@udea.edu.co |
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Tobón Orozco, Ángela MaríaArango Arteaga, MyrthaFernández, DaríoRestrepo Moreno, Ángela2021-11-14T12:15:16Z2021-11-14T12:15:16Z20031058-4838http://hdl.handle.net/10495/2408510.1086/3750751537-6591ABSTRACT: We describe the case of a diabetic patient who developed a severe invasive fungal infection due to Rhizopus species postoperatively after a dual heart/kidney transplantation with subsequent intensive immunosuppressive therapy. No improvement was noted with amphotericin B (deoxycholate) therapy, but salvage treatment with the new azole antifungal posaconazole (200 mg orally 4 times daily) resulted in dramatic clinical improvement as early as 1 week after the initiation of therapy that continued through 23 weeks of treatment, with marked clinical, mycological, and radiological improvements and no adverse events.COL00137094application/pdfengUniversity of Chicago PressMicología Médica y ExperimentalChicago, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTCASOReporte de casohttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/Mucormycosis (Zygomycosis) in a heart-Kidney trasplant recipient : recovery after posaconazole therapyDiabetes mellitusTrasplante de RiñónKidney TransplantationZigomicosisZygomycosisAnfotericina BAmphotericin BMucormicosisMucormycosisRhizopusÁcido DesoxicólicoDeoxycholic AcidReceptores de TrasplantesTransplant RecipientsRiñónKidneyCorazónHeartInmunosupresiónInmunosuppressionClin. Infect. Dis.Clinical Infectious Diseases148814913611ORIGINALRestrepoAngela_2003_MucormycosisTransplantPosaconazole.pdfRestrepoAngela_2003_MucormycosisTransplantPosaconazole.pdfReporte de casoapplication/pdf123438http://bibliotecadigital.udea.edu.co/bitstream/10495/24085/1/RestrepoAngela_2003_MucormycosisTransplantPosaconazole.pdf560951dac9cc5ff1f1db4f8e93d176d2MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8823http://bibliotecadigital.udea.edu.co/bitstream/10495/24085/2/license_rdfb88b088d9957e670ce3b3fbe2eedbc13MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/24085/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/24085oai:bibliotecadigital.udea.edu.co:10495/240852022-04-22 10:20:49.718Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |