Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia

ABSTRACT : Anopheles darlingi is an important vector of Plasmodium spp. in several malaria-endemic regions of Colom-bia. This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Co...

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Autores:
Gutiérrez Builes, Lina Andrea
Fernández Gómez, Giovan
Conn, Jan E.
González, John J.
Castro, Martha I.
Luckhart, Shirley
Correa Ochoa, Margarita María
Tipo de recurso:
Article of investigation
Fecha de publicación:
2010
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/20576
Acceso en línea:
http://hdl.handle.net/10495/20576
Palabra clave:
Malaria
Anopheles
Córdoba (Colombia)
Antioquia (Colombia)
Diptera: Culicidae
Rights
openAccess
License
https://creativecommons.org/licenses/by/2.5/co/
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oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/20576
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
title Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
spellingShingle Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
Malaria
Anopheles
Córdoba (Colombia)
Antioquia (Colombia)
Diptera: Culicidae
title_short Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
title_full Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
title_fullStr Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
title_full_unstemmed Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
title_sort Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
dc.creator.fl_str_mv Gutiérrez Builes, Lina Andrea
Fernández Gómez, Giovan
Conn, Jan E.
González, John J.
Castro, Martha I.
Luckhart, Shirley
Correa Ochoa, Margarita María
dc.contributor.author.none.fl_str_mv Gutiérrez Builes, Lina Andrea
Fernández Gómez, Giovan
Conn, Jan E.
González, John J.
Castro, Martha I.
Luckhart, Shirley
Correa Ochoa, Margarita María
dc.subject.decs.none.fl_str_mv Malaria
Anopheles
topic Malaria
Anopheles
Córdoba (Colombia)
Antioquia (Colombia)
Diptera: Culicidae
dc.subject.lemb.none.fl_str_mv Córdoba (Colombia)
Antioquia (Colombia)
dc.subject.proposal.spa.fl_str_mv Diptera: Culicidae
description ABSTRACT : Anopheles darlingi is an important vector of Plasmodium spp. in several malaria-endemic regions of Colom-bia. This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Colombia, to better understand the potential contribution of population genetics to local malaria control programs. Microsatellite loci: nuclear white and cytochrome oxidase sub-unit I ( COI ) gene sequences were analyzed. The northern white gene lineage was exclusively distributed in Córdoba and Antioquia and shared COI haplotypes were highly represented in mosquitoes from both states. COI analyses showed these An. darlingi are genetically closer to Central American populations than southern South American populations. Overall microsatellites and COI analysis showed low to moderate genetic differentiation among populations in north-western Colombia. Given the existence of high gene flow between An. darlingi populations of Córdoba and Antioquia, integrated vector control strategies could be developed in this region of Colombia.
publishDate 2010
dc.date.issued.none.fl_str_mv 2010
dc.date.accessioned.none.fl_str_mv 2021-07-01T22:17:04Z
dc.date.available.none.fl_str_mv 2021-07-01T22:17:04Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.hasversion.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/ART
dc.type.local.spa.fl_str_mv Artículo de investigación
format http://purl.org/coar/resource_type/c_2df8fbb1
status_str publishedVersion
dc.identifier.issn.none.fl_str_mv 0002-9637
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/20576
dc.identifier.doi.none.fl_str_mv 10.4269/ajtmh.2010.09-0381
dc.identifier.eissn.none.fl_str_mv 1476-1645
identifier_str_mv 0002-9637
10.4269/ajtmh.2010.09-0381
1476-1645
url http://hdl.handle.net/10495/20576
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Am. j. trop. med. hyg.
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.*.fl_str_mv https://creativecommons.org/licenses/by/2.5/co/
dc.rights.accessrights.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.creativecommons.spa.fl_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/co/
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.format.extent.spa.fl_str_mv 10
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv American Society of Tropical Medicine and Hygiene
dc.publisher.group.spa.fl_str_mv Microbiología Molecular
dc.publisher.place.spa.fl_str_mv Baltimore, Estados Unidos
institution Universidad de Antioquia
bitstream.url.fl_str_mv https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/2/license.txt
https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/1/GutierrezLina_2010_GeneticVariationMalaria.pdf
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
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repository.name.fl_str_mv Repositorio Institucional Universidad de Antioquia
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spelling Gutiérrez Builes, Lina AndreaFernández Gómez, GiovanConn, Jan E.González, John J.Castro, Martha I.Luckhart, ShirleyCorrea Ochoa, Margarita María2021-07-01T22:17:04Z2021-07-01T22:17:04Z20100002-9637http://hdl.handle.net/10495/2057610.4269/ajtmh.2010.09-03811476-1645ABSTRACT : Anopheles darlingi is an important vector of Plasmodium spp. in several malaria-endemic regions of Colom-bia. This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Colombia, to better understand the potential contribution of population genetics to local malaria control programs. Microsatellite loci: nuclear white and cytochrome oxidase sub-unit I ( COI ) gene sequences were analyzed. The northern white gene lineage was exclusively distributed in Córdoba and Antioquia and shared COI haplotypes were highly represented in mosquitoes from both states. COI analyses showed these An. darlingi are genetically closer to Central American populations than southern South American populations. Overall microsatellites and COI analysis showed low to moderate genetic differentiation among populations in north-western Colombia. Given the existence of high gene flow between An. darlingi populations of Córdoba and Antioquia, integrated vector control strategies could be developed in this region of Colombia.COL001374610application/pdfengAmerican Society of Tropical Medicine and HygieneMicrobiología MolecularBaltimore, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, ColombiaMalariaAnophelesCórdoba (Colombia)Antioquia (Colombia)Diptera: CulicidaeAm. j. trop. med. hyg.American Journal of Tropical Medicine and Hygiene3847831LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALGutierrezLina_2010_GeneticVariationMalaria.pdfGutierrezLina_2010_GeneticVariationMalaria.pdfArtículo de investigaciónapplication/pdf890047https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/1/GutierrezLina_2010_GeneticVariationMalaria.pdf343223985c076d84597a734e43ee9b71MD5110495/20576oai:bibliotecadigital.udea.edu.co:10495/205762022-04-22 10:17:46.581Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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