Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia
ABSTRACT : Anopheles darlingi is an important vector of Plasmodium spp. in several malaria-endemic regions of Colom-bia. This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Co...
- Autores:
-
Gutiérrez Builes, Lina Andrea
Fernández Gómez, Giovan
Conn, Jan E.
González, John J.
Castro, Martha I.
Luckhart, Shirley
Correa Ochoa, Margarita María
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2010
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/20576
- Acceso en línea:
- http://hdl.handle.net/10495/20576
- Palabra clave:
- Malaria
Anopheles
Córdoba (Colombia)
Antioquia (Colombia)
Diptera: Culicidae
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/2.5/co/
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UDEA2 |
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Repositorio UdeA |
repository_id_str |
|
dc.title.spa.fl_str_mv |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
title |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
spellingShingle |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia Malaria Anopheles Córdoba (Colombia) Antioquia (Colombia) Diptera: Culicidae |
title_short |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
title_full |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
title_fullStr |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
title_full_unstemmed |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
title_sort |
Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, Colombia |
dc.creator.fl_str_mv |
Gutiérrez Builes, Lina Andrea Fernández Gómez, Giovan Conn, Jan E. González, John J. Castro, Martha I. Luckhart, Shirley Correa Ochoa, Margarita María |
dc.contributor.author.none.fl_str_mv |
Gutiérrez Builes, Lina Andrea Fernández Gómez, Giovan Conn, Jan E. González, John J. Castro, Martha I. Luckhart, Shirley Correa Ochoa, Margarita María |
dc.subject.decs.none.fl_str_mv |
Malaria Anopheles |
topic |
Malaria Anopheles Córdoba (Colombia) Antioquia (Colombia) Diptera: Culicidae |
dc.subject.lemb.none.fl_str_mv |
Córdoba (Colombia) Antioquia (Colombia) |
dc.subject.proposal.spa.fl_str_mv |
Diptera: Culicidae |
description |
ABSTRACT : Anopheles darlingi is an important vector of Plasmodium spp. in several malaria-endemic regions of Colom-bia. This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Colombia, to better understand the potential contribution of population genetics to local malaria control programs. Microsatellite loci: nuclear white and cytochrome oxidase sub-unit I ( COI ) gene sequences were analyzed. The northern white gene lineage was exclusively distributed in Córdoba and Antioquia and shared COI haplotypes were highly represented in mosquitoes from both states. COI analyses showed these An. darlingi are genetically closer to Central American populations than southern South American populations. Overall microsatellites and COI analysis showed low to moderate genetic differentiation among populations in north-western Colombia. Given the existence of high gene flow between An. darlingi populations of Córdoba and Antioquia, integrated vector control strategies could be developed in this region of Colombia. |
publishDate |
2010 |
dc.date.issued.none.fl_str_mv |
2010 |
dc.date.accessioned.none.fl_str_mv |
2021-07-01T22:17:04Z |
dc.date.available.none.fl_str_mv |
2021-07-01T22:17:04Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
dc.type.local.spa.fl_str_mv |
Artículo de investigación |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
status_str |
publishedVersion |
dc.identifier.issn.none.fl_str_mv |
0002-9637 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/20576 |
dc.identifier.doi.none.fl_str_mv |
10.4269/ajtmh.2010.09-0381 |
dc.identifier.eissn.none.fl_str_mv |
1476-1645 |
identifier_str_mv |
0002-9637 10.4269/ajtmh.2010.09-0381 1476-1645 |
url |
http://hdl.handle.net/10495/20576 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Am. j. trop. med. hyg. |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
https://creativecommons.org/licenses/by/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
dc.format.extent.spa.fl_str_mv |
10 |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
American Society of Tropical Medicine and Hygiene |
dc.publisher.group.spa.fl_str_mv |
Microbiología Molecular |
dc.publisher.place.spa.fl_str_mv |
Baltimore, Estados Unidos |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/2/license.txt https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/1/GutierrezLina_2010_GeneticVariationMalaria.pdf |
bitstream.checksum.fl_str_mv |
8a4605be74aa9ea9d79846c1fba20a33 343223985c076d84597a734e43ee9b71 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
_version_ |
1812173299845693440 |
spelling |
Gutiérrez Builes, Lina AndreaFernández Gómez, GiovanConn, Jan E.González, John J.Castro, Martha I.Luckhart, ShirleyCorrea Ochoa, Margarita María2021-07-01T22:17:04Z2021-07-01T22:17:04Z20100002-9637http://hdl.handle.net/10495/2057610.4269/ajtmh.2010.09-03811476-1645ABSTRACT : Anopheles darlingi is an important vector of Plasmodium spp. in several malaria-endemic regions of Colom-bia. This study was conducted to test genetic variation of An. darlingi at a microgeographic scale (approximately 100 km) from localities in Córdoba and Antioquia states, in western Colombia, to better understand the potential contribution of population genetics to local malaria control programs. Microsatellite loci: nuclear white and cytochrome oxidase sub-unit I ( COI ) gene sequences were analyzed. The northern white gene lineage was exclusively distributed in Córdoba and Antioquia and shared COI haplotypes were highly represented in mosquitoes from both states. COI analyses showed these An. darlingi are genetically closer to Central American populations than southern South American populations. Overall microsatellites and COI analysis showed low to moderate genetic differentiation among populations in north-western Colombia. Given the existence of high gene flow between An. darlingi populations of Córdoba and Antioquia, integrated vector control strategies could be developed in this region of Colombia.COL001374610application/pdfengAmerican Society of Tropical Medicine and HygieneMicrobiología MolecularBaltimore, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Microgeographic genetic variation of the malaria vector Anopheles darlingi Root (Diptera: Culicidae) from Cordobá and Antioquia, ColombiaMalariaAnophelesCórdoba (Colombia)Antioquia (Colombia)Diptera: CulicidaeAm. j. trop. med. hyg.American Journal of Tropical Medicine and Hygiene3847831LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALGutierrezLina_2010_GeneticVariationMalaria.pdfGutierrezLina_2010_GeneticVariationMalaria.pdfArtículo de investigaciónapplication/pdf890047https://bibliotecadigital.udea.edu.co/bitstream/10495/20576/1/GutierrezLina_2010_GeneticVariationMalaria.pdf343223985c076d84597a734e43ee9b71MD5110495/20576oai:bibliotecadigital.udea.edu.co:10495/205762022-04-22 10:17:46.581Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |