Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency

ABSTRACT : The authors report two cases of adrenal insufficiency secondary to infiltration of the adrenal glands by Paracoccidioides brasiliensis. The first patient had been treated for a chronic multifocal form of paracoccidiodomycosis 11 years ago. The diagnosis of the mycosis was done simultaneou...

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Autores:
Agudelo Restrepo, Carlos Andrés
Muñoz, Carolina
Ramírez, Alex
Gutiérrez, Jonhairo
Vélez, Santiago
Pérez, Juan Camilo
Vélez Hoyos, Alejandro
Tobón Orozco, Ángela María
Restrepo Moreno, Ángela
Tipo de recurso:
Article of investigation
Fecha de publicación:
2009
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/29392
Acceso en línea:
http://hdl.handle.net/10495/29392
Palabra clave:
Paracoccidioidomicosis
Paracoccidioidomycosis
Hidrocortisona
Hydrocortisone
Insuficiencia Suprarrenal
Adrenal Insufficiency
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/2.5/co/
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oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/29392
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
title Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
spellingShingle Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
Paracoccidioidomicosis
Paracoccidioidomycosis
Hidrocortisona
Hydrocortisone
Insuficiencia Suprarrenal
Adrenal Insufficiency
title_short Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
title_full Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
title_fullStr Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
title_full_unstemmed Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
title_sort Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiency
dc.creator.fl_str_mv Agudelo Restrepo, Carlos Andrés
Muñoz, Carolina
Ramírez, Alex
Gutiérrez, Jonhairo
Vélez, Santiago
Pérez, Juan Camilo
Vélez Hoyos, Alejandro
Tobón Orozco, Ángela María
Restrepo Moreno, Ángela
dc.contributor.author.none.fl_str_mv Agudelo Restrepo, Carlos Andrés
Muñoz, Carolina
Ramírez, Alex
Gutiérrez, Jonhairo
Vélez, Santiago
Pérez, Juan Camilo
Vélez Hoyos, Alejandro
Tobón Orozco, Ángela María
Restrepo Moreno, Ángela
dc.subject.decs.none.fl_str_mv Paracoccidioidomicosis
Paracoccidioidomycosis
Hidrocortisona
Hydrocortisone
Insuficiencia Suprarrenal
Adrenal Insufficiency
topic Paracoccidioidomicosis
Paracoccidioidomycosis
Hidrocortisona
Hydrocortisone
Insuficiencia Suprarrenal
Adrenal Insufficiency
description ABSTRACT : The authors report two cases of adrenal insufficiency secondary to infiltration of the adrenal glands by Paracoccidioides brasiliensis. The first patient had been treated for a chronic multifocal form of paracoccidiodomycosis 11 years ago. The diagnosis of the mycosis was done simultaneous with that of the adrenal insufficiency in the second patient. In both patients the diagnosis was done by direct visualization of fungus in adrenal biopsies. They were treated with hormonal supplements and itraconazol by 12 and six months, without relapses during the follow-up period.
publishDate 2009
dc.date.issued.none.fl_str_mv 2009
dc.date.accessioned.none.fl_str_mv 2022-06-23T23:24:29Z
dc.date.available.none.fl_str_mv 2022-06-23T23:24:29Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.type.hasversion.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.type.local.spa.fl_str_mv Artículo de investigación
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status_str publishedVersion
dc.identifier.issn.none.fl_str_mv 0036-4665
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/29392
dc.identifier.doi.none.fl_str_mv 10.1590/S0036-46652009000100008
dc.identifier.eissn.none.fl_str_mv 1678-9946
identifier_str_mv 0036-4665
10.1590/S0036-46652009000100008
1678-9946
url http://hdl.handle.net/10495/29392
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Rev. Inst. Med. Trop. São Paulo.
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/2.5/co/
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dc.publisher.spa.fl_str_mv Universidade de São Paulo, Faculdade de Medicina
dc.publisher.group.spa.fl_str_mv Micología Médica y Experimental
dc.publisher.place.spa.fl_str_mv Sao Paulo, Brasil
institution Universidad de Antioquia
bitstream.url.fl_str_mv https://bibliotecadigital.udea.edu.co/bitstream/10495/29392/1/RestrepoAngela_2009_IdentificationParacoccidioides%20Biopsies.pdf
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spelling Agudelo Restrepo, Carlos AndrésMuñoz, CarolinaRamírez, AlexGutiérrez, JonhairoVélez, SantiagoPérez, Juan CamiloVélez Hoyos, AlejandroTobón Orozco, Ángela MaríaRestrepo Moreno, Ángela2022-06-23T23:24:29Z2022-06-23T23:24:29Z20090036-4665http://hdl.handle.net/10495/2939210.1590/S0036-466520090001000081678-9946ABSTRACT : The authors report two cases of adrenal insufficiency secondary to infiltration of the adrenal glands by Paracoccidioides brasiliensis. The first patient had been treated for a chronic multifocal form of paracoccidiodomycosis 11 years ago. The diagnosis of the mycosis was done simultaneous with that of the adrenal insufficiency in the second patient. In both patients the diagnosis was done by direct visualization of fungus in adrenal biopsies. They were treated with hormonal supplements and itraconazol by 12 and six months, without relapses during the follow-up period.COL00137094application/pdfengUniversidade de São Paulo, Faculdade de MedicinaMicología Médica y ExperimentalSao Paulo, Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Identification of Paracoccidioides brasiliensis in adrenal glands biopsies of two patients with paracoccidioidomycosis and adrenal insufficiencyParacoccidioidomicosisParacoccidioidomycosisHidrocortisonaHydrocortisoneInsuficiencia SuprarrenalAdrenal InsufficiencyRev. Inst. Med. Trop. São Paulo.Revista do Instituto de Medicina Tropical de Sao Paulo4548511ORIGINALRestrepoAngela_2009_IdentificationParacoccidioides Biopsies.pdfRestrepoAngela_2009_IdentificationParacoccidioides Biopsies.pdfArtículo de investigaciónapplication/pdf1006023https://bibliotecadigital.udea.edu.co/bitstream/10495/29392/1/RestrepoAngela_2009_IdentificationParacoccidioides%20Biopsies.pdf7d2467d78ac9084bf0baa36aa6b77522MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81051https://bibliotecadigital.udea.edu.co/bitstream/10495/29392/2/license_rdfe2060682c9c70d4d30c83c51448f4eedMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/29392/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/29392oai:bibliotecadigital.udea.edu.co:10495/293922022-06-23 18:24:30.081Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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