Outlining the Ancestry Landscape of Colombian Admixed Populations
ABSTRACT: The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also...
- Autores:
-
Ossa Reyes, Humberto
Aquino, Juliana
Pereira, Rui
Ibarra Rodríguez, Adriana Alexandra
Ossa Trujillo, Rafael Humberto
Pérez Sepúlveda, Luz Adriana
Granda Agudelo, Juan David
Lattig Matiz, Maria Claudia
Groot de Restrepo, Helena
Fagundes de Carvalho, Elizeu
Gusmão, Leonor
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/25043
- Acceso en línea:
- http://hdl.handle.net/10495/25043
- Palabra clave:
- Colombia
Filogeografía
Phylogeography
Genética de población humana
Human population genetics
Europa
Deriva genética
Genetic drift
Paleogenética
http://aims.fao.org/aos/agrovoc/c_37333
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
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|
dc.title.spa.fl_str_mv |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
title |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
spellingShingle |
Outlining the Ancestry Landscape of Colombian Admixed Populations Colombia Filogeografía Phylogeography Genética de población humana Human population genetics Europa Deriva genética Genetic drift Paleogenética http://aims.fao.org/aos/agrovoc/c_37333 |
title_short |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
title_full |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
title_fullStr |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
title_full_unstemmed |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
title_sort |
Outlining the Ancestry Landscape of Colombian Admixed Populations |
dc.creator.fl_str_mv |
Ossa Reyes, Humberto Aquino, Juliana Pereira, Rui Ibarra Rodríguez, Adriana Alexandra Ossa Trujillo, Rafael Humberto Pérez Sepúlveda, Luz Adriana Granda Agudelo, Juan David Lattig Matiz, Maria Claudia Groot de Restrepo, Helena Fagundes de Carvalho, Elizeu Gusmão, Leonor |
dc.contributor.author.none.fl_str_mv |
Ossa Reyes, Humberto Aquino, Juliana Pereira, Rui Ibarra Rodríguez, Adriana Alexandra Ossa Trujillo, Rafael Humberto Pérez Sepúlveda, Luz Adriana Granda Agudelo, Juan David Lattig Matiz, Maria Claudia Groot de Restrepo, Helena Fagundes de Carvalho, Elizeu Gusmão, Leonor |
dc.subject.decs.none.fl_str_mv |
Colombia Filogeografía Phylogeography |
topic |
Colombia Filogeografía Phylogeography Genética de población humana Human population genetics Europa Deriva genética Genetic drift Paleogenética http://aims.fao.org/aos/agrovoc/c_37333 |
dc.subject.lemb.none.fl_str_mv |
Genética de población humana Human population genetics Europa |
dc.subject.agrovoc.none.fl_str_mv |
Deriva genética Genetic drift |
dc.subject.proposal.spa.fl_str_mv |
Paleogenética |
dc.subject.agrovocuri.none.fl_str_mv |
http://aims.fao.org/aos/agrovoc/c_37333 |
description |
ABSTRACT: The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also became part of the Colombian population. Therefore, the genepool of the current Colombian population results from the admixture of Native Americans, Europeans and Africans. This admixture occurred differently in each region of the country, producing a clearly stratified population. Considering the importance of population substructure in both clinical and forensic genetics, we sought to investigate and compare patterns of genetic ancestry in Colombia by studying samples from Native and non-Native populations living in its 5 continental regions: the Andes, Caribe, Amazonia, Orinoquía, and Pacific regions. For this purpose, 46 AIM-Indels were genotyped in 761 non-related individuals from current populations. Previously published genotype data from 214 Colombian Natives from five communities were used for population comparisons. Significant differences were observed between Native and non-Native populations, among non-Native populations from different regions and among Native populations from different ethnic groups. The Pacific was the region with the highest African ancestry, Amazonia harboured the highest Native ancestry and the Andean and Orinoquían regions showed the highest proportion of European ancestry. The Andean region was further sub-divided into 6 sub-regions: North East, Central West, Central East, West, South West and South East. Among these regions, the South West region showed a significantly lower European admixture than the other regions. Hardy-Weinberg equilibrium and variance values of ancestry among individuals within populations showed a potential stratification of the Pacific population. |
publishDate |
2011 |
dc.date.issued.none.fl_str_mv |
2011 |
dc.date.accessioned.none.fl_str_mv |
2021-12-14T13:07:38Z |
dc.date.available.none.fl_str_mv |
2021-12-14T13:07:38Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
dc.type.local.spa.fl_str_mv |
Artículo de investigación |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
status_str |
publishedVersion |
dc.identifier.citation.spa.fl_str_mv |
Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R., Pérez L., et al. (2016) Outlining the Ancestry Landscape of Colombian Admixed Populations. PLoS ONE 11(10): 1-15. doi:10.1371/journal.pone.0164414 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/25043 |
dc.identifier.doi.none.fl_str_mv |
10.1371/journal.pone.0164414 |
dc.identifier.eissn.none.fl_str_mv |
1932-6203 |
identifier_str_mv |
Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R., Pérez L., et al. (2016) Outlining the Ancestry Landscape of Colombian Admixed Populations. PLoS ONE 11(10): 1-15. doi:10.1371/journal.pone.0164414 10.1371/journal.pone.0164414 1932-6203 |
url |
http://hdl.handle.net/10495/25043 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
PLoS ONE. |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
dc.format.extent.spa.fl_str_mv |
15 |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Public Library of Science |
dc.publisher.group.spa.fl_str_mv |
Identificación Genética - IdentiGEN |
dc.publisher.place.spa.fl_str_mv |
San Francisco, Estados Unidos |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/1/IbarraAdriana_2016_AncestryColombianPopulations.pdf https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/2/license_rdf https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/3/license.txt |
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Repositorio Institucional Universidad de Antioquia |
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andres.perez@udea.edu.co |
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spelling |
Ossa Reyes, HumbertoAquino, JulianaPereira, RuiIbarra Rodríguez, Adriana AlexandraOssa Trujillo, Rafael HumbertoPérez Sepúlveda, Luz AdrianaGranda Agudelo, Juan DavidLattig Matiz, Maria ClaudiaGroot de Restrepo, HelenaFagundes de Carvalho, ElizeuGusmão, Leonor2021-12-14T13:07:38Z2021-12-14T13:07:38Z2011Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R., Pérez L., et al. (2016) Outlining the Ancestry Landscape of Colombian Admixed Populations. PLoS ONE 11(10): 1-15. doi:10.1371/journal.pone.0164414http://hdl.handle.net/10495/2504310.1371/journal.pone.01644141932-6203ABSTRACT: The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also became part of the Colombian population. Therefore, the genepool of the current Colombian population results from the admixture of Native Americans, Europeans and Africans. This admixture occurred differently in each region of the country, producing a clearly stratified population. Considering the importance of population substructure in both clinical and forensic genetics, we sought to investigate and compare patterns of genetic ancestry in Colombia by studying samples from Native and non-Native populations living in its 5 continental regions: the Andes, Caribe, Amazonia, Orinoquía, and Pacific regions. For this purpose, 46 AIM-Indels were genotyped in 761 non-related individuals from current populations. Previously published genotype data from 214 Colombian Natives from five communities were used for population comparisons. Significant differences were observed between Native and non-Native populations, among non-Native populations from different regions and among Native populations from different ethnic groups. The Pacific was the region with the highest African ancestry, Amazonia harboured the highest Native ancestry and the Andean and Orinoquían regions showed the highest proportion of European ancestry. The Andean region was further sub-divided into 6 sub-regions: North East, Central West, Central East, West, South West and South East. Among these regions, the South West region showed a significantly lower European admixture than the other regions. Hardy-Weinberg equilibrium and variance values of ancestry among individuals within populations showed a potential stratification of the Pacific population.COL003542915application/pdfengPublic Library of ScienceIdentificación Genética - IdentiGENSan Francisco, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Outlining the Ancestry Landscape of Colombian Admixed PopulationsColombiaFilogeografíaPhylogeographyGenética de población humanaHuman population geneticsEuropaDeriva genéticaGenetic driftPaleogenéticahttp://aims.fao.org/aos/agrovoc/c_37333PLoS ONE.PLoS ONE1151110ORIGINALIbarraAdriana_2016_AncestryColombianPopulations.pdfIbarraAdriana_2016_AncestryColombianPopulations.pdfArtículo de investigaciónapplication/pdf2261902https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/1/IbarraAdriana_2016_AncestryColombianPopulations.pdf3b80087651c4ae5ede25c9d3df9b082fMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/2/license_rdf1646d1f6b96dbbbc38035efc9239ac9cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/25043oai:bibliotecadigital.udea.edu.co:10495/250432023-04-11 16:09:26.179Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |