Outlining the Ancestry Landscape of Colombian Admixed Populations

ABSTRACT: The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also...

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Autores:
Ossa Reyes, Humberto
Aquino, Juliana
Pereira, Rui
Ibarra Rodríguez, Adriana Alexandra
Ossa Trujillo, Rafael Humberto
Pérez Sepúlveda, Luz Adriana
Granda Agudelo, Juan David
Lattig Matiz, Maria Claudia
Groot de Restrepo, Helena
Fagundes de Carvalho, Elizeu
Gusmão, Leonor
Tipo de recurso:
Article of investigation
Fecha de publicación:
2011
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/25043
Acceso en línea:
http://hdl.handle.net/10495/25043
Palabra clave:
Colombia
Filogeografía
Phylogeography
Genética de población humana
Human population genetics
Europa
Deriva genética
Genetic drift
Paleogenética
http://aims.fao.org/aos/agrovoc/c_37333
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/
id UDEA2_2e09d614e603ab9203ac5bc355eba30a
oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/25043
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Outlining the Ancestry Landscape of Colombian Admixed Populations
title Outlining the Ancestry Landscape of Colombian Admixed Populations
spellingShingle Outlining the Ancestry Landscape of Colombian Admixed Populations
Colombia
Filogeografía
Phylogeography
Genética de población humana
Human population genetics
Europa
Deriva genética
Genetic drift
Paleogenética
http://aims.fao.org/aos/agrovoc/c_37333
title_short Outlining the Ancestry Landscape of Colombian Admixed Populations
title_full Outlining the Ancestry Landscape of Colombian Admixed Populations
title_fullStr Outlining the Ancestry Landscape of Colombian Admixed Populations
title_full_unstemmed Outlining the Ancestry Landscape of Colombian Admixed Populations
title_sort Outlining the Ancestry Landscape of Colombian Admixed Populations
dc.creator.fl_str_mv Ossa Reyes, Humberto
Aquino, Juliana
Pereira, Rui
Ibarra Rodríguez, Adriana Alexandra
Ossa Trujillo, Rafael Humberto
Pérez Sepúlveda, Luz Adriana
Granda Agudelo, Juan David
Lattig Matiz, Maria Claudia
Groot de Restrepo, Helena
Fagundes de Carvalho, Elizeu
Gusmão, Leonor
dc.contributor.author.none.fl_str_mv Ossa Reyes, Humberto
Aquino, Juliana
Pereira, Rui
Ibarra Rodríguez, Adriana Alexandra
Ossa Trujillo, Rafael Humberto
Pérez Sepúlveda, Luz Adriana
Granda Agudelo, Juan David
Lattig Matiz, Maria Claudia
Groot de Restrepo, Helena
Fagundes de Carvalho, Elizeu
Gusmão, Leonor
dc.subject.decs.none.fl_str_mv Colombia
Filogeografía
Phylogeography
topic Colombia
Filogeografía
Phylogeography
Genética de población humana
Human population genetics
Europa
Deriva genética
Genetic drift
Paleogenética
http://aims.fao.org/aos/agrovoc/c_37333
dc.subject.lemb.none.fl_str_mv Genética de población humana
Human population genetics
Europa
dc.subject.agrovoc.none.fl_str_mv Deriva genética
Genetic drift
dc.subject.proposal.spa.fl_str_mv Paleogenética
dc.subject.agrovocuri.none.fl_str_mv http://aims.fao.org/aos/agrovoc/c_37333
description ABSTRACT: The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also became part of the Colombian population. Therefore, the genepool of the current Colombian population results from the admixture of Native Americans, Europeans and Africans. This admixture occurred differently in each region of the country, producing a clearly stratified population. Considering the importance of population substructure in both clinical and forensic genetics, we sought to investigate and compare patterns of genetic ancestry in Colombia by studying samples from Native and non-Native populations living in its 5 continental regions: the Andes, Caribe, Amazonia, Orinoquía, and Pacific regions. For this purpose, 46 AIM-Indels were genotyped in 761 non-related individuals from current populations. Previously published genotype data from 214 Colombian Natives from five communities were used for population comparisons. Significant differences were observed between Native and non-Native populations, among non-Native populations from different regions and among Native populations from different ethnic groups. The Pacific was the region with the highest African ancestry, Amazonia harboured the highest Native ancestry and the Andean and Orinoquían regions showed the highest proportion of European ancestry. The Andean region was further sub-divided into 6 sub-regions: North East, Central West, Central East, West, South West and South East. Among these regions, the South West region showed a significantly lower European admixture than the other regions. Hardy-Weinberg equilibrium and variance values of ancestry among individuals within populations showed a potential stratification of the Pacific population.
publishDate 2011
dc.date.issued.none.fl_str_mv 2011
dc.date.accessioned.none.fl_str_mv 2021-12-14T13:07:38Z
dc.date.available.none.fl_str_mv 2021-12-14T13:07:38Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
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dc.type.local.spa.fl_str_mv Artículo de investigación
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dc.identifier.citation.spa.fl_str_mv Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R., Pérez L., et al. (2016) Outlining the Ancestry Landscape of Colombian Admixed Populations. PLoS ONE 11(10): 1-15. doi:10.1371/journal.pone.0164414
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/25043
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pone.0164414
dc.identifier.eissn.none.fl_str_mv 1932-6203
identifier_str_mv Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R., Pérez L., et al. (2016) Outlining the Ancestry Landscape of Colombian Admixed Populations. PLoS ONE 11(10): 1-15. doi:10.1371/journal.pone.0164414
10.1371/journal.pone.0164414
1932-6203
url http://hdl.handle.net/10495/25043
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv PLoS ONE.
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by/2.5/co/
dc.rights.accessrights.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.creativecommons.spa.fl_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.5/co/
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dc.publisher.spa.fl_str_mv Public Library of Science
dc.publisher.group.spa.fl_str_mv Identificación Genética - IdentiGEN
dc.publisher.place.spa.fl_str_mv San Francisco, Estados Unidos
institution Universidad de Antioquia
bitstream.url.fl_str_mv https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/1/IbarraAdriana_2016_AncestryColombianPopulations.pdf
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spelling Ossa Reyes, HumbertoAquino, JulianaPereira, RuiIbarra Rodríguez, Adriana AlexandraOssa Trujillo, Rafael HumbertoPérez Sepúlveda, Luz AdrianaGranda Agudelo, Juan DavidLattig Matiz, Maria ClaudiaGroot de Restrepo, HelenaFagundes de Carvalho, ElizeuGusmão, Leonor2021-12-14T13:07:38Z2021-12-14T13:07:38Z2011Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R., Pérez L., et al. (2016) Outlining the Ancestry Landscape of Colombian Admixed Populations. PLoS ONE 11(10): 1-15. doi:10.1371/journal.pone.0164414http://hdl.handle.net/10495/2504310.1371/journal.pone.01644141932-6203ABSTRACT: The ancestry of the Colombian population comprises a large number of well differentiated Native communities belonging to diverse linguistic groups. In the late fifteenth century, a process of admixture was initiated with the arrival of the Europeans, and several years later, Africans also became part of the Colombian population. Therefore, the genepool of the current Colombian population results from the admixture of Native Americans, Europeans and Africans. This admixture occurred differently in each region of the country, producing a clearly stratified population. Considering the importance of population substructure in both clinical and forensic genetics, we sought to investigate and compare patterns of genetic ancestry in Colombia by studying samples from Native and non-Native populations living in its 5 continental regions: the Andes, Caribe, Amazonia, Orinoquía, and Pacific regions. For this purpose, 46 AIM-Indels were genotyped in 761 non-related individuals from current populations. Previously published genotype data from 214 Colombian Natives from five communities were used for population comparisons. Significant differences were observed between Native and non-Native populations, among non-Native populations from different regions and among Native populations from different ethnic groups. The Pacific was the region with the highest African ancestry, Amazonia harboured the highest Native ancestry and the Andean and Orinoquían regions showed the highest proportion of European ancestry. The Andean region was further sub-divided into 6 sub-regions: North East, Central West, Central East, West, South West and South East. Among these regions, the South West region showed a significantly lower European admixture than the other regions. Hardy-Weinberg equilibrium and variance values of ancestry among individuals within populations showed a potential stratification of the Pacific population.COL003542915application/pdfengPublic Library of ScienceIdentificación Genética - IdentiGENSan Francisco, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Outlining the Ancestry Landscape of Colombian Admixed PopulationsColombiaFilogeografíaPhylogeographyGenética de población humanaHuman population geneticsEuropaDeriva genéticaGenetic driftPaleogenéticahttp://aims.fao.org/aos/agrovoc/c_37333PLoS ONE.PLoS ONE1151110ORIGINALIbarraAdriana_2016_AncestryColombianPopulations.pdfIbarraAdriana_2016_AncestryColombianPopulations.pdfArtículo de investigaciónapplication/pdf2261902https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/1/IbarraAdriana_2016_AncestryColombianPopulations.pdf3b80087651c4ae5ede25c9d3df9b082fMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/2/license_rdf1646d1f6b96dbbbc38035efc9239ac9cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/25043/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/25043oai:bibliotecadigital.udea.edu.co:10495/250432023-04-11 16:09:26.179Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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