Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso
ABSTRACT: Mononucleosis syndrome is frequently associated with the Epstein Barr virus (EBV), which is related with Burkitt lymphoma, non-differentiated nose-throat carcinoma and lympho-proliferative illness. There is a serology association between the infection and Hodgkin’s disease and, in addition...
- Autores:
-
Jaramillo Arbeláez, Patricia Elena
Cuéllar Ambrosi, Francisco
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2010
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- spa
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/10177
- Acceso en línea:
- http://hdl.handle.net/10495/10177
https://revistas.udea.edu.co/index.php/hm/article/view/5227
- Palabra clave:
- Burkitt Lymphoma
Cholestasic hepatitis
Epstein-Barr Virus
Hepatitis colestásica
Linfocitos
Linfoma de Burkitt
Lymphocytes
Mononucleosis infecciosa
Virus de Epstein-Barr
- Rights
- openAccess
- License
- Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
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Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| dc.title.alternative.spa.fl_str_mv |
Severe mononucleosis syndrome with cholestasic hepatitis in a non-immunocompromised patient : case report |
| title |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| spellingShingle |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso Burkitt Lymphoma Cholestasic hepatitis Epstein-Barr Virus Hepatitis colestásica Linfocitos Linfoma de Burkitt Lymphocytes Mononucleosis infecciosa Virus de Epstein-Barr |
| title_short |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| title_full |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| title_fullStr |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| title_full_unstemmed |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| title_sort |
Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un caso |
| dc.creator.fl_str_mv |
Jaramillo Arbeláez, Patricia Elena Cuéllar Ambrosi, Francisco |
| dc.contributor.author.none.fl_str_mv |
Jaramillo Arbeláez, Patricia Elena Cuéllar Ambrosi, Francisco |
| dc.subject.none.fl_str_mv |
Burkitt Lymphoma Cholestasic hepatitis Epstein-Barr Virus Hepatitis colestásica Linfocitos Linfoma de Burkitt Lymphocytes Mononucleosis infecciosa Virus de Epstein-Barr |
| topic |
Burkitt Lymphoma Cholestasic hepatitis Epstein-Barr Virus Hepatitis colestásica Linfocitos Linfoma de Burkitt Lymphocytes Mononucleosis infecciosa Virus de Epstein-Barr |
| description |
ABSTRACT: Mononucleosis syndrome is frequently associated with the Epstein Barr virus (EBV), which is related with Burkitt lymphoma, non-differentiated nose-throat carcinoma and lympho-proliferative illness. There is a serology association between the infection and Hodgkin’s disease and, in addition, the pathogenesis of the uterus neck cancer and EBV relation is studied. The reported clinic case patient presented a meaningful increase in reactive lymphocytes with abnormal morphological characteristics and important clinical complications such as multiple adenopathies, hepatomegaly, splenomegaly, hypertransaminases and hyperbilirubinemia, which excluded various differential diagnoses. Finally, according to the clinical history, the diagnostic results and the evolution of the patient, it is concluded that the diagnosis is a mononucleosis syndrome in a patient without immune deficiency and with cholestasic hepatitis due to an infection with EBV. The immunohistochemical studies of the ganglion biopsy allowed the exclusion of a diagnosis of lymphoma; consequently, the activated cells are not neoplastic. |
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2010 |
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2010 |
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2018-10-04T20:28:48Z |
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2018-10-04T20:28:48Z |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Jaramillo-Arbeláez PA, Cuéllar-Ambrosi F. Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente: presentación de un caso. Hechos Microbiol. 2010;1(1):87-90. |
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2145-8898 |
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http://hdl.handle.net/10495/10177 |
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https://revistas.udea.edu.co/index.php/hm/article/view/5227 |
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Jaramillo-Arbeláez PA, Cuéllar-Ambrosi F. Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente: presentación de un caso. Hechos Microbiol. 2010;1(1):87-90. 2145-8898 |
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http://hdl.handle.net/10495/10177 https://revistas.udea.edu.co/index.php/hm/article/view/5227 |
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spa |
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spa |
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Hechos Microbiol. |
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Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) |
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Universidad de Antioquia, Escuela de Microbiología |
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Hematopatología Molecular |
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Medellín, Colombia |
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Universidad de Antioquia |
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Jaramillo Arbeláez, Patricia ElenaCuéllar Ambrosi, Francisco2018-10-04T20:28:48Z2018-10-04T20:28:48Z2010Jaramillo-Arbeláez PA, Cuéllar-Ambrosi F. Síndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente: presentación de un caso. Hechos Microbiol. 2010;1(1):87-90.2145-8898http://hdl.handle.net/10495/10177https://revistas.udea.edu.co/index.php/hm/article/view/5227ABSTRACT: Mononucleosis syndrome is frequently associated with the Epstein Barr virus (EBV), which is related with Burkitt lymphoma, non-differentiated nose-throat carcinoma and lympho-proliferative illness. There is a serology association between the infection and Hodgkin’s disease and, in addition, the pathogenesis of the uterus neck cancer and EBV relation is studied. The reported clinic case patient presented a meaningful increase in reactive lymphocytes with abnormal morphological characteristics and important clinical complications such as multiple adenopathies, hepatomegaly, splenomegaly, hypertransaminases and hyperbilirubinemia, which excluded various differential diagnoses. Finally, according to the clinical history, the diagnostic results and the evolution of the patient, it is concluded that the diagnosis is a mononucleosis syndrome in a patient without immune deficiency and with cholestasic hepatitis due to an infection with EBV. The immunohistochemical studies of the ganglion biopsy allowed the exclusion of a diagnosis of lymphoma; consequently, the activated cells are not neoplastic.RESUMEN: El síndrome mononucleósico se asocia frecuentemente con el virus Epstein Barr, el cual se relaciona con linfoma de Burkitt, carcinoma de nasofaringe indiferenciado y enfermedad linfoproliferativa. Existe una asociación serológica entre la infección y la enfermedad de Hodgkin y, además, está en estudio la patogénesis de la relación del Epstein Barr con el cáncer del cuello uterino. El paciente del caso clínico que se reporta presenta un aumento significativo de linfocitos reactivos con características morfológicas anormales y complicaciones clínicas importantes como: múltiples adenopatías, hepatomegalia, esplenomegalia, hipertransaminasemia e hiperbilirrubinemia, lo cual obligó a descartar varios diagnósticos diferenciales. Finalmente, según la historia clínica, los resultados diagnósticos y la evolución del paciente, se concluye que el diagnóstico es un síndrome mononucleósico en un paciente inmunocompetente con hepatitis colestásica, debido a una infección por VEB. Los estudios de inmunohistoquímica de la biopsia del ganglio permitieron descartar el diagnóstico de linfoma; por lo tanto, las células activadas no corresponden a células neoplásicas.COL0043226application/pdfspaUniversidad de Antioquia, Escuela de MicrobiologíaHematopatología MolecularMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTCASOReporte de casohttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Burkitt LymphomaCholestasic hepatitisEpstein-Barr VirusHepatitis colestásicaLinfocitosLinfoma de BurkittLymphocytesMononucleosis infecciosaVirus de Epstein-BarrSíndrome mononucleósico severo con hepatitis colestásica en un paciente inmunocompetente : presentación de un casoSevere mononucleosis syndrome with cholestasic hepatitis in a non-immunocompromised patient : case reportHechos Microbiol.Hechos Microbiológicos879011ORIGINALJaramilloPatricia_2010_SindromeMononucleosicoHepatitis.pdfJaramilloPatricia_2010_SindromeMononucleosicoHepatitis.pdfReporte de casoapplication/pdf1231913http://bibliotecadigital.udea.edu.co/bitstream/10495/10177/1/JaramilloPatricia_2010_SindromeMononucleosicoHepatitis.pdf1f29b86b6cd0064dd71b47f9190c9360MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://bibliotecadigital.udea.edu.co/bitstream/10495/10177/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/10177/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfLicenciaapplication/rdf+xml; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/10177/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/10177/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5510495/10177oai:bibliotecadigital.udea.edu.co:10495/101772022-04-22 10:16:25.109Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |