Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
ABSTRACT: Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or th...
- Autores:
-
Abad Londoño, Verónica
Jaramillo Arango, Carolina
López Alarcón, Yúrika Paola
Marín Agudelo, Alejandro
Yepes Delgado, Carlos Enrique
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/32368
- Acceso en línea:
- https://hdl.handle.net/10495/32368
- Palabra clave:
- Enfermedad Celíaca
Celiac Disease
Diabetes Mellitus Tipo 1
Diabetes Mellitus, Type 1
Autoinmunidad
Autoimmunity
Prevalencia
Prevalence
Tissue transglutaminase autoantibody
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/2.5/co/
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|
dc.title.spa.fl_str_mv |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
title |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
spellingShingle |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia Enfermedad Celíaca Celiac Disease Diabetes Mellitus Tipo 1 Diabetes Mellitus, Type 1 Autoinmunidad Autoimmunity Prevalencia Prevalence Tissue transglutaminase autoantibody |
title_short |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
title_full |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
title_fullStr |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
title_full_unstemmed |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
title_sort |
Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia |
dc.creator.fl_str_mv |
Abad Londoño, Verónica Jaramillo Arango, Carolina López Alarcón, Yúrika Paola Marín Agudelo, Alejandro Yepes Delgado, Carlos Enrique |
dc.contributor.author.none.fl_str_mv |
Abad Londoño, Verónica Jaramillo Arango, Carolina López Alarcón, Yúrika Paola Marín Agudelo, Alejandro Yepes Delgado, Carlos Enrique |
dc.subject.decs.none.fl_str_mv |
Enfermedad Celíaca Celiac Disease Diabetes Mellitus Tipo 1 Diabetes Mellitus, Type 1 Autoinmunidad Autoimmunity Prevalencia Prevalence |
topic |
Enfermedad Celíaca Celiac Disease Diabetes Mellitus Tipo 1 Diabetes Mellitus, Type 1 Autoinmunidad Autoimmunity Prevalencia Prevalence Tissue transglutaminase autoantibody |
dc.subject.proposal.spa.fl_str_mv |
Tissue transglutaminase autoantibody |
description |
ABSTRACT: Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or thyroid comorbidity. Objective: To assess the prevalence of celiac autoimmunity in children and adolescents diagnosed with type 1 diabetes mellitus and to identify the clinical profile of patients with celiac autoimmunity. Methods: One hundred patients with type 1 diabetes mellitus under 18 years, who consulted the department of pediatric endocrinology at Hospital Pablo Tobón Uribe – Medellin, between May and December 2015, were included. The concentration of antibodies, anti-tissue transglutaminase IgA, and total immunoglobulin A were measured in all patients; also a survey of signs and symptoms of celiac disease was applied. Results: Patients were aged between 3 and 17 years. Four had celiac autoimmunity evidenced by positive anti-tissue transglutaminase IgA. The clinical profile of patients with celiac autoimmunity was patient |
publishDate |
2018 |
dc.date.issued.none.fl_str_mv |
2018 |
dc.date.accessioned.none.fl_str_mv |
2022-11-26T03:22:08Z |
dc.date.available.none.fl_str_mv |
2022-11-26T03:22:08Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
dc.type.local.spa.fl_str_mv |
Artículo de investigación |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
status_str |
publishedVersion |
dc.identifier.citation.spa.fl_str_mv |
Jaramillo-Arango C, Lopez-Alarcon Y, Marín-Agudelo A, et al. Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia. Endocrinol Metab Int J. 2018;6(3):167-171. DOI: 10.15406/emij.2018.06.00172 |
dc.identifier.issn.none.fl_str_mv |
2093-596X |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/32368 |
dc.identifier.doi.none.fl_str_mv |
10.15406/emij.2018.06.00172 |
dc.identifier.eissn.none.fl_str_mv |
2093-5978 |
identifier_str_mv |
Jaramillo-Arango C, Lopez-Alarcon Y, Marín-Agudelo A, et al. Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia. Endocrinol Metab Int J. 2018;6(3):167-171. DOI: 10.15406/emij.2018.06.00172 2093-596X 10.15406/emij.2018.06.00172 2093-5978 |
url |
https://hdl.handle.net/10495/32368 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Endocrinol. Metab. |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc/4.0/ |
dc.format.extent.spa.fl_str_mv |
5 |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Korean Endocrine Society |
dc.publisher.group.spa.fl_str_mv |
Respuesta Social en Salud |
dc.publisher.place.spa.fl_str_mv |
Seúl, Corea del Sur |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
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bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
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1812173096165048320 |
spelling |
Abad Londoño, VerónicaJaramillo Arango, CarolinaLópez Alarcón, Yúrika PaolaMarín Agudelo, AlejandroYepes Delgado, Carlos Enrique2022-11-26T03:22:08Z2022-11-26T03:22:08Z2018Jaramillo-Arango C, Lopez-Alarcon Y, Marín-Agudelo A, et al. Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia. Endocrinol Metab Int J. 2018;6(3):167-171. DOI: 10.15406/emij.2018.06.001722093-596Xhttps://hdl.handle.net/10495/3236810.15406/emij.2018.06.001722093-5978ABSTRACT: Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or thyroid comorbidity. Objective: To assess the prevalence of celiac autoimmunity in children and adolescents diagnosed with type 1 diabetes mellitus and to identify the clinical profile of patients with celiac autoimmunity. Methods: One hundred patients with type 1 diabetes mellitus under 18 years, who consulted the department of pediatric endocrinology at Hospital Pablo Tobón Uribe – Medellin, between May and December 2015, were included. The concentration of antibodies, anti-tissue transglutaminase IgA, and total immunoglobulin A were measured in all patients; also a survey of signs and symptoms of celiac disease was applied. Results: Patients were aged between 3 and 17 years. Four had celiac autoimmunity evidenced by positive anti-tissue transglutaminase IgA. The clinical profile of patients with celiac autoimmunity was patientCOL00620435application/pdfengKorean Endocrine SocietyRespuesta Social en SaludSeúl, Corea del Surinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc/4.0/Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in ColombiaEnfermedad CelíacaCeliac DiseaseDiabetes Mellitus Tipo 1Diabetes Mellitus, Type 1AutoinmunidadAutoimmunityPrevalenciaPrevalenceTissue transglutaminase autoantibodyEndocrinol. Metab.Endocrinology and Metabolism16717163CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8933https://bibliotecadigital.udea.edu.co/bitstream/10495/32368/2/license_rdfc0c92b0ffc8b7d22d9cf56754a416a76MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/32368/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD53ORIGINALAbadVerónica_2018_PrevalenceCeliacAutoimmunity.pdfAbadVerónica_2018_PrevalenceCeliacAutoimmunity.pdfArtículo de investigaciónapplication/pdf549935https://bibliotecadigital.udea.edu.co/bitstream/10495/32368/1/AbadVer%c3%b3nica_2018_PrevalenceCeliacAutoimmunity.pdfecbbaec28cae23a0ae8a4e931457e8ffMD5110495/32368oai:bibliotecadigital.udea.edu.co:10495/323682022-11-25 22:22:10.662Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |