Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia

ABSTRACT: Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or th...

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Autores:
Abad Londoño, Verónica
Jaramillo Arango, Carolina
López Alarcón, Yúrika Paola
Marín Agudelo, Alejandro
Yepes Delgado, Carlos Enrique
Tipo de recurso:
Article of investigation
Fecha de publicación:
2018
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/32368
Acceso en línea:
https://hdl.handle.net/10495/32368
Palabra clave:
Enfermedad Celíaca
Celiac Disease
Diabetes Mellitus Tipo 1
Diabetes Mellitus, Type 1
Autoinmunidad
Autoimmunity
Prevalencia
Prevalence
Tissue transglutaminase autoantibody
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc/2.5/co/
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oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/32368
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
title Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
spellingShingle Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
Enfermedad Celíaca
Celiac Disease
Diabetes Mellitus Tipo 1
Diabetes Mellitus, Type 1
Autoinmunidad
Autoimmunity
Prevalencia
Prevalence
Tissue transglutaminase autoantibody
title_short Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
title_full Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
title_fullStr Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
title_full_unstemmed Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
title_sort Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia
dc.creator.fl_str_mv Abad Londoño, Verónica
Jaramillo Arango, Carolina
López Alarcón, Yúrika Paola
Marín Agudelo, Alejandro
Yepes Delgado, Carlos Enrique
dc.contributor.author.none.fl_str_mv Abad Londoño, Verónica
Jaramillo Arango, Carolina
López Alarcón, Yúrika Paola
Marín Agudelo, Alejandro
Yepes Delgado, Carlos Enrique
dc.subject.decs.none.fl_str_mv Enfermedad Celíaca
Celiac Disease
Diabetes Mellitus Tipo 1
Diabetes Mellitus, Type 1
Autoinmunidad
Autoimmunity
Prevalencia
Prevalence
topic Enfermedad Celíaca
Celiac Disease
Diabetes Mellitus Tipo 1
Diabetes Mellitus, Type 1
Autoinmunidad
Autoimmunity
Prevalencia
Prevalence
Tissue transglutaminase autoantibody
dc.subject.proposal.spa.fl_str_mv Tissue transglutaminase autoantibody
description ABSTRACT: Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or thyroid comorbidity. Objective: To assess the prevalence of celiac autoimmunity in children and adolescents diagnosed with type 1 diabetes mellitus and to identify the clinical profile of patients with celiac autoimmunity. Methods: One hundred patients with type 1 diabetes mellitus under 18 years, who consulted the department of pediatric endocrinology at Hospital Pablo Tobón Uribe – Medellin, between May and December 2015, were included. The concentration of antibodies, anti-tissue transglutaminase IgA, and total immunoglobulin A were measured in all patients; also a survey of signs and symptoms of celiac disease was applied. Results: Patients were aged between 3 and 17 years. Four had celiac autoimmunity evidenced by positive anti-tissue transglutaminase IgA. The clinical profile of patients with celiac autoimmunity was patient
publishDate 2018
dc.date.issued.none.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2022-11-26T03:22:08Z
dc.date.available.none.fl_str_mv 2022-11-26T03:22:08Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.type.local.spa.fl_str_mv Artículo de investigación
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dc.identifier.citation.spa.fl_str_mv Jaramillo-Arango C, Lopez-Alarcon Y, Marín-Agudelo A, et al. Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia. Endocrinol Metab Int J. 2018;6(3):167-171. DOI: 10.15406/emij.2018.06.00172
dc.identifier.issn.none.fl_str_mv 2093-596X
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10495/32368
dc.identifier.doi.none.fl_str_mv 10.15406/emij.2018.06.00172
dc.identifier.eissn.none.fl_str_mv 2093-5978
identifier_str_mv Jaramillo-Arango C, Lopez-Alarcon Y, Marín-Agudelo A, et al. Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia. Endocrinol Metab Int J. 2018;6(3):167-171. DOI: 10.15406/emij.2018.06.00172
2093-596X
10.15406/emij.2018.06.00172
2093-5978
url https://hdl.handle.net/10495/32368
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Endocrinol. Metab.
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc/2.5/co/
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eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/2.5/co/
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dc.publisher.spa.fl_str_mv Korean Endocrine Society
dc.publisher.group.spa.fl_str_mv Respuesta Social en Salud
dc.publisher.place.spa.fl_str_mv Seúl, Corea del Sur
institution Universidad de Antioquia
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spelling Abad Londoño, VerónicaJaramillo Arango, CarolinaLópez Alarcón, Yúrika PaolaMarín Agudelo, AlejandroYepes Delgado, Carlos Enrique2022-11-26T03:22:08Z2022-11-26T03:22:08Z2018Jaramillo-Arango C, Lopez-Alarcon Y, Marín-Agudelo A, et al. Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in Colombia. Endocrinol Metab Int J. 2018;6(3):167-171. DOI: 10.15406/emij.2018.06.001722093-596Xhttps://hdl.handle.net/10495/3236810.15406/emij.2018.06.001722093-5978ABSTRACT: Background: The prevalence of celiac disease in patients with type 1 diabetes mellitus is 5 to 10 times higher than in the general population. However, diagnosis is difficult given that patients are asymptomatic or with nonspecific symptoms and are confused with poor glycemic control or thyroid comorbidity. Objective: To assess the prevalence of celiac autoimmunity in children and adolescents diagnosed with type 1 diabetes mellitus and to identify the clinical profile of patients with celiac autoimmunity. Methods: One hundred patients with type 1 diabetes mellitus under 18 years, who consulted the department of pediatric endocrinology at Hospital Pablo Tobón Uribe – Medellin, between May and December 2015, were included. The concentration of antibodies, anti-tissue transglutaminase IgA, and total immunoglobulin A were measured in all patients; also a survey of signs and symptoms of celiac disease was applied. Results: Patients were aged between 3 and 17 years. Four had celiac autoimmunity evidenced by positive anti-tissue transglutaminase IgA. The clinical profile of patients with celiac autoimmunity was patientCOL00620435application/pdfengKorean Endocrine SocietyRespuesta Social en SaludSeúl, Corea del Surinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc/4.0/Prevalence of celiac autoimmunity in children and adolescents with type 1 diabetes mellitus in a high complexity hospital in ColombiaEnfermedad CelíacaCeliac DiseaseDiabetes Mellitus Tipo 1Diabetes Mellitus, Type 1AutoinmunidadAutoimmunityPrevalenciaPrevalenceTissue transglutaminase autoantibodyEndocrinol. Metab.Endocrinology and Metabolism16717163CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8933https://bibliotecadigital.udea.edu.co/bitstream/10495/32368/2/license_rdfc0c92b0ffc8b7d22d9cf56754a416a76MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/32368/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD53ORIGINALAbadVerónica_2018_PrevalenceCeliacAutoimmunity.pdfAbadVerónica_2018_PrevalenceCeliacAutoimmunity.pdfArtículo de investigaciónapplication/pdf549935https://bibliotecadigital.udea.edu.co/bitstream/10495/32368/1/AbadVer%c3%b3nica_2018_PrevalenceCeliacAutoimmunity.pdfecbbaec28cae23a0ae8a4e931457e8ffMD5110495/32368oai:bibliotecadigital.udea.edu.co:10495/323682022-11-25 22:22:10.662Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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