Y-Chromosome Evidence for Differing Ancient Demographic Histories in the Americas

ABSTRACT: To scrutinize the male ancestry of extant Native American populations, we examined eight biallelic and six microsatellite polymorphisms from the nonrecombining portion of the Y chromosome, in 438 individuals from 24 Native American populations (1 Na Dene´ and 23 South Amerinds) and in 404 Mongolians. One of the biallelic markers typed is a recently identified mutation (M242) characterizing a novel founder Native American haplogroup. The distribution, relatedness, and diversity of Y lineages in Native Americans indicate a differentiated male ancestry for populations from North and South America, strongly supporting a diverse demographic history for populations from these areas. These data are consistent with the occurrence of two major male migrations from southern/ central Siberia to the Americas (with the second migration being restricted to North America) and a shared ancestry in central Asia for some of the initial migrants to Europe and the Americas. The microsatellite diversity and distribution of a Y lineage specific to South America (Q-M19) indicates that certain Amerind populations have been isolated since the initial colonization of the region, suggesting an early onset for tribalization of Native Americans. Age estimates based on Y-chromosome microsatellite diversity place the initial settlement of the American continent at ∼14,000 years ago, in relative agreement with the age of well-established archaeological evidence.

• Autores: Bortolini, María Catira; Salzano, Francisco; Thomas, Mark; Stuart, Steven; Nasanen, Selja; Bau, Claiton; Hutz, Mara; Layrisse, Zulay; Petzl Erle, Maria; Tsuneto, Luiza; Hill, Kim; Hurtado, Ana; Castro de Guerra, Dinorah; Torres, Maria; Groot, Helena; Michalski, Roman; Nymadawa, Pagbajabyn; Bedoya Berrío, Gabriel de Jesús; Bradman, Neil; Labuda, Damian; Ruíz Linares, Andrés
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2003
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/26752
• Acceso en línea: http://hdl.handle.net/10495/26752
• Palabra clave: Grupo de Ascendencia Continental Asiática; Asian Continental Ancestry Group; Cromosoma Y; Y Chromosome; Emigración e Inmigración; Emigration and Immigration; Marcadores Genéticos; Genetic Markers; Genética de Población; Genetics, Population; Haplotipos; Haplotypes; Indios Norteamericanos - genética; Indians, North American - genetics; Indios Sudamericanos - genética; Indians, South American - genetics; Repeticiones de Microsatélite; Microsatellite Repeats; Polimorfismo Genético; Polymorphism, Genetic
• Rights: openAccess
• License: http://creativecommons.org/licenses/by-nc-nd/2.5/co/