Y-Chromosome Evidence for Differing Ancient Demographic Histories in the Americas

ABSTRACT: To scrutinize the male ancestry of extant Native American populations, we examined eight biallelic and six microsatellite polymorphisms from the nonrecombining portion of the Y chromosome, in 438 individuals from 24 Native American populations (1 Na Dene´ and 23 South Amerinds) and in 404...

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Autores:
Bortolini, María Catira
Salzano, Francisco
Thomas, Mark
Stuart, Steven
Nasanen, Selja
Bau, Claiton
Hutz, Mara
Layrisse, Zulay
Petzl Erle, Maria
Tsuneto, Luiza
Hill, Kim
Hurtado, Ana
Castro de Guerra, Dinorah
Torres, Maria
Groot, Helena
Michalski, Roman
Nymadawa, Pagbajabyn
Bedoya Berrío, Gabriel de Jesús
Bradman, Neil
Labuda, Damian
Ruíz Linares, Andrés
Tipo de recurso:
Article of investigation
Fecha de publicación:
2003
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/26752
Acceso en línea:
http://hdl.handle.net/10495/26752
Palabra clave:
Grupo de Ascendencia Continental Asiática
Asian Continental Ancestry Group
Cromosoma Y
Y Chromosome
Emigración e Inmigración
Emigration and Immigration
Marcadores Genéticos
Genetic Markers
Genética de Población
Genetics, Population
Haplotipos
Haplotypes
Indios Norteamericanos - genética
Indians, North American - genetics
Indios Sudamericanos - genética
Indians, South American - genetics
Repeticiones de Microsatélite
Microsatellite Repeats
Polimorfismo Genético
Polymorphism, Genetic
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
Description
Summary:ABSTRACT: To scrutinize the male ancestry of extant Native American populations, we examined eight biallelic and six microsatellite polymorphisms from the nonrecombining portion of the Y chromosome, in 438 individuals from 24 Native American populations (1 Na Dene´ and 23 South Amerinds) and in 404 Mongolians. One of the biallelic markers typed is a recently identified mutation (M242) characterizing a novel founder Native American haplogroup. The distribution, relatedness, and diversity of Y lineages in Native Americans indicate a differentiated male ancestry for populations from North and South America, strongly supporting a diverse demographic history for populations from these areas. These data are consistent with the occurrence of two major male migrations from southern/ central Siberia to the Americas (with the second migration being restricted to North America) and a shared ancestry in central Asia for some of the initial migrants to Europe and the Americas. The microsatellite diversity and distribution of a Y lineage specific to South America (Q-M19) indicates that certain Amerind populations have been isolated since the initial colonization of the region, suggesting an early onset for tribalization of Native Americans. Age estimates based on Y-chromosome microsatellite diversity place the initial settlement of the American continent at ∼14,000 years ago, in relative agreement with the age of well-established archaeological evidence.