Prurito crónico

ABSTRACT: Chronic pruritus is defi ned as an unpleasant sensation on the skin that causes scratching and lasts more than six weeks. This symptom may be a manifestation of a cutaneous or systemic disease and it jeopardizes the patients’ quality of life, constantly altering their sleep and daily activ...

Full description

Autores:
Villa Arango, Ana María
Velásquez Lopera, Margarita María
Cardona Villa, Ricardo
Tipo de recurso:
Review article
Fecha de publicación:
2019
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/43075
Acceso en línea:
https://hdl.handle.net/10495/43075
Palabra clave:
Comezón
Itching
Prurito
Pruritus
Enfermedades de la Piel
Skin Diseases
http://id.loc.gov/authorities/subjects/sh85108048
https://id.nlm.nih.gov/mesh/D011537
https://id.nlm.nih.gov/mesh/D012871
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.title.spa.fl_str_mv Prurito crónico
dc.title.translated.spa.fl_str_mv Chronic pruritus
title Prurito crónico
spellingShingle Prurito crónico
Comezón
Itching
Prurito
Pruritus
Enfermedades de la Piel
Skin Diseases
http://id.loc.gov/authorities/subjects/sh85108048
https://id.nlm.nih.gov/mesh/D011537
https://id.nlm.nih.gov/mesh/D012871
title_short Prurito crónico
title_full Prurito crónico
title_fullStr Prurito crónico
title_full_unstemmed Prurito crónico
title_sort Prurito crónico
dc.creator.fl_str_mv Villa Arango, Ana María
Velásquez Lopera, Margarita María
Cardona Villa, Ricardo
dc.contributor.author.none.fl_str_mv Villa Arango, Ana María
Velásquez Lopera, Margarita María
Cardona Villa, Ricardo
dc.contributor.researchgroup.spa.fl_str_mv Centro de de Investigaciones Dermatológicas
Grupo de Alergología Clínica y Experimental (GACE)
dc.subject.lcsh.none.fl_str_mv Comezón
Itching
topic Comezón
Itching
Prurito
Pruritus
Enfermedades de la Piel
Skin Diseases
http://id.loc.gov/authorities/subjects/sh85108048
https://id.nlm.nih.gov/mesh/D011537
https://id.nlm.nih.gov/mesh/D012871
dc.subject.decs.none.fl_str_mv Prurito
Pruritus
Enfermedades de la Piel
Skin Diseases
dc.subject.lcshuri.none.fl_str_mv http://id.loc.gov/authorities/subjects/sh85108048
dc.subject.meshuri.none.fl_str_mv https://id.nlm.nih.gov/mesh/D011537
https://id.nlm.nih.gov/mesh/D012871
description ABSTRACT: Chronic pruritus is defi ned as an unpleasant sensation on the skin that causes scratching and lasts more than six weeks. This symptom may be a manifestation of a cutaneous or systemic disease and it jeopardizes the patients’ quality of life, constantly altering their sleep and daily activities. The pathophysiology is complex and it includes multiple mediators and their respective receptors which, through different signaling pathways, carry information through type C nerve fi bers towards the thalamus; from where it is distributed to various areas of the cerebral cortex. The understanding of these mechanisms has made it possible to identify potential therapeutic targets and the development of molecules that are increasingly more effective and safer for patients. The present review aims to give a vision of the diagnostic and therapeutic handling of patients with chronic pruritus.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2024-11-03T04:38:28Z
dc.date.available.none.fl_str_mv 2024-11-03T04:38:28Z
dc.type.spa.fl_str_mv Artículo de revisión
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dc.identifier.doi.none.fl_str_mv 10.29262/ram.v66i1.345
dc.identifier.eissn.none.fl_str_mv 2448-9190
identifier_str_mv 0002-5151
10.29262/ram.v66i1.345
2448-9190
url https://hdl.handle.net/10495/43075
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Rev. Alergia Mex.
dc.relation.citationendpage.spa.fl_str_mv 98
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dc.relation.citationstartpage.spa.fl_str_mv 85
dc.relation.citationvolume.spa.fl_str_mv 66
dc.relation.ispartofjournal.spa.fl_str_mv Revista Alergia México
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dc.format.extent.spa.fl_str_mv 14 páginas
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dc.publisher.spa.fl_str_mv Colegio Mexicano, Asma e Inmunología Clínica A.C.
dc.publisher.place.spa.fl_str_mv Tecamachalco, México
institution Universidad de Antioquia
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spelling Villa Arango, Ana MaríaVelásquez Lopera, Margarita MaríaCardona Villa, RicardoCentro de de Investigaciones DermatológicasGrupo de Alergología Clínica y Experimental (GACE)2024-11-03T04:38:28Z2024-11-03T04:38:28Z20190002-5151https://hdl.handle.net/10495/4307510.29262/ram.v66i1.3452448-9190ABSTRACT: Chronic pruritus is defi ned as an unpleasant sensation on the skin that causes scratching and lasts more than six weeks. This symptom may be a manifestation of a cutaneous or systemic disease and it jeopardizes the patients’ quality of life, constantly altering their sleep and daily activities. The pathophysiology is complex and it includes multiple mediators and their respective receptors which, through different signaling pathways, carry information through type C nerve fi bers towards the thalamus; from where it is distributed to various areas of the cerebral cortex. The understanding of these mechanisms has made it possible to identify potential therapeutic targets and the development of molecules that are increasingly more effective and safer for patients. The present review aims to give a vision of the diagnostic and therapeutic handling of patients with chronic pruritus.RESUMEN: El prurito crónico se defi ne como una sensación no placentera de la piel que induce el rascado y que dura más de seis semanas. Este síntoma puede ser la manifestación de una enfermedad cutánea o sistémica y compromete la calidad de vida de los pacientes, alterando de forma consistente el sueño y las actividades diarias. La fi siopatología es compleja e incluye múltiples mediadores y sus respectivos receptores, que a través de diferentes vías de señalización llevan información por las fi bras nerviosas tipo C hacia el tálamo, desde donde se distribuye a diversas zonas de la corteza cerebral. La comprensión de estos mecanismos ha permitido identifi car posibles blancos terapéuticos y el desarrollo de moléculas cada vez más efectivas y seguras para los pacientes. La presente revisión pretende dar una visión acerca del manejo diagnóstico y terapéutico de los pacientes con prurito crónico.COL0130733COL005956714 páginasapplication/pdfengColegio Mexicano, Asma e Inmunología Clínica A.C.Tecamachalco, Méxicohttp://creativecommons.org/licenses/by-nc-nd/2.5/co/https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2ComezónItchingPruritoPruritusEnfermedades de la PielSkin Diseaseshttp://id.loc.gov/authorities/subjects/sh85108048https://id.nlm.nih.gov/mesh/D011537https://id.nlm.nih.gov/mesh/D012871Prurito crónicoChronic pruritusArtículo de revisiónhttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRev. 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