Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms

ABSTRACT : Coccidioides spp is considered to be one of the most important fungal pathogen of humans. It is the causal agent of coccidioidomycosis, a systemic and endemic mycosis with a significant impact on public health, mainly in the United States, Central and South America. The host innate immune...

Full description

Autores:
González Marín, Ángel Augusto
Tipo de recurso:
Review article
Fecha de publicación:
2013
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/25038
Acceso en línea:
http://hdl.handle.net/10495/25038
Palabra clave:
Coccidioides
Coccidioidomicosis
Coccidioidomycosis
Inmunorrespuesta
Immune response
Toll-like receptor (TLR)
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/2.5/co/
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dc.title.spa.fl_str_mv Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
title Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
spellingShingle Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
Coccidioides
Coccidioidomicosis
Coccidioidomycosis
Inmunorrespuesta
Immune response
Toll-like receptor (TLR)
title_short Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
title_full Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
title_fullStr Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
title_full_unstemmed Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
title_sort Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanisms
dc.creator.fl_str_mv González Marín, Ángel Augusto
dc.contributor.author.none.fl_str_mv González Marín, Ángel Augusto
dc.subject.decs.none.fl_str_mv Coccidioides
Coccidioidomicosis
Coccidioidomycosis
topic Coccidioides
Coccidioidomicosis
Coccidioidomycosis
Inmunorrespuesta
Immune response
Toll-like receptor (TLR)
dc.subject.lemb.none.fl_str_mv Inmunorrespuesta
Immune response
dc.subject.proposal.spa.fl_str_mv Toll-like receptor (TLR)
description ABSTRACT : Coccidioides spp is considered to be one of the most important fungal pathogen of humans. It is the causal agent of coccidioidomycosis, a systemic and endemic mycosis with a significant impact on public health, mainly in the United States, Central and South America. The host innate immune system appears to play an important role in the initial interaction and recognition of Coccidioides infection and the subsequent development of adaptive immunity. In this review article, I focus on the interaction between the innate immune response and Coccidioides in an attempt to increase our knowledge of the pathogenesis of this fungus.
publishDate 2013
dc.date.issued.none.fl_str_mv 2013
dc.date.accessioned.none.fl_str_mv 2021-12-14T02:22:21Z
dc.date.available.none.fl_str_mv 2021-12-14T02:22:21Z
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dc.identifier.citation.spa.fl_str_mv González A (2013) Innate Immune Response to the Dimorphic Fungal Pathogen Coccidioides: Molecular and Cellular Mechanisms. J Clin Cell Immunol S13: 001. doi:10.4172/2155-9899.S13-001
dc.identifier.issn.none.fl_str_mv 2155-9899
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/25038
dc.identifier.doi.none.fl_str_mv 10.4172/2155-9899.S13-001
identifier_str_mv González A (2013) Innate Immune Response to the Dimorphic Fungal Pathogen Coccidioides: Molecular and Cellular Mechanisms. J Clin Cell Immunol S13: 001. doi:10.4172/2155-9899.S13-001
2155-9899
10.4172/2155-9899.S13-001
url http://hdl.handle.net/10495/25038
dc.language.iso.spa.fl_str_mv eng
language eng
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dc.publisher.spa.fl_str_mv OMICS Publishing Group
dc.publisher.group.spa.fl_str_mv Grupo de Investigación en Microbiología Básica y Aplicada-Microba
dc.publisher.place.spa.fl_str_mv Sunnyvale, Estados Unidos
institution Universidad de Antioquia
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spelling González Marín, Ángel Augusto2021-12-14T02:22:21Z2021-12-14T02:22:21Z2013González A (2013) Innate Immune Response to the Dimorphic Fungal Pathogen Coccidioides: Molecular and Cellular Mechanisms. J Clin Cell Immunol S13: 001. doi:10.4172/2155-9899.S13-0012155-9899http://hdl.handle.net/10495/2503810.4172/2155-9899.S13-001ABSTRACT : Coccidioides spp is considered to be one of the most important fungal pathogen of humans. It is the causal agent of coccidioidomycosis, a systemic and endemic mycosis with a significant impact on public health, mainly in the United States, Central and South America. The host innate immune system appears to play an important role in the initial interaction and recognition of Coccidioides infection and the subsequent development of adaptive immunity. In this review article, I focus on the interaction between the innate immune response and Coccidioides in an attempt to increase our knowledge of the pathogenesis of this fungus.COL01261316application/pdfengOMICS Publishing GroupGrupo de Investigación en Microbiología Básica y Aplicada-MicrobaSunnyvale, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVArtículo de revisiónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Innate immune response to the dimorphic fungal pathogen Coccidioides : molecular and cellular mechanismsCoccidioidesCoccidioidomicosisCoccidioidomycosisInmunorrespuestaImmune responseToll-like receptor (TLR)Journal of Clinicla and Cellular Immunology1613ORIGINALAngelGonzalez_2013_InnateDimorphicPathogen.pdfAngelGonzalez_2013_InnateDimorphicPathogen.pdfArtículo de revisiónapplication/pdf1564184http://bibliotecadigital.udea.edu.co/bitstream/10495/25038/1/AngelGonzalez_2013_InnateDimorphicPathogen.pdfc8f2e3917b7fdeb8a55b70e0e80c345aMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81051http://bibliotecadigital.udea.edu.co/bitstream/10495/25038/2/license_rdfe2060682c9c70d4d30c83c51448f4eedMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/25038/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/25038oai:bibliotecadigital.udea.edu.co:10495/250382022-04-22 10:22:28.754Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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