Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy
ABSTRACT: To determine the reliability and accuracy of the sulfosalicylic acid test in the fast detection and semi-quantitative analysis of proteinuria. Methods: Prospective, descriptive study at Hospital Universitario San Vicente de Paúl in Medellín, Colombia. Ninety eight women with proteinuria an...
- Autores:
-
Velásquez Penagos, Jesús Arnulfo
Zuleta Tobón, John Jairo
López Jaramillo, José Duván
Gómez Marulanda, Natalia Lucía
Gómez Gallego, Jáder de Jesús
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2011
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/12672
- Acceso en línea:
- http://hdl.handle.net/10495/12672
- Palabra clave:
- Pregnancy-Induced Hypertension
Preeclampsia
Proteinuria
Sulfosalicylic Acid Test
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-sa/4.0/
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Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| dc.title.translated.spa.fl_str_mv |
Uso del ácido sulfosalicílico para la detección de proteinuria y su aplicación a problemas de hipertensión en el embarazo |
| title |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| spellingShingle |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy Pregnancy-Induced Hypertension Preeclampsia Proteinuria Sulfosalicylic Acid Test |
| title_short |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| title_full |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| title_fullStr |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| title_full_unstemmed |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| title_sort |
Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy |
| dc.creator.fl_str_mv |
Velásquez Penagos, Jesús Arnulfo Zuleta Tobón, John Jairo López Jaramillo, José Duván Gómez Marulanda, Natalia Lucía Gómez Gallego, Jáder de Jesús |
| dc.contributor.author.none.fl_str_mv |
Velásquez Penagos, Jesús Arnulfo Zuleta Tobón, John Jairo López Jaramillo, José Duván Gómez Marulanda, Natalia Lucía Gómez Gallego, Jáder de Jesús |
| dc.contributor.researchgroup.spa.fl_str_mv |
Nacer, Salud Sexual y Reproductiva |
| dc.subject.none.fl_str_mv |
Pregnancy-Induced Hypertension Preeclampsia Proteinuria Sulfosalicylic Acid Test |
| topic |
Pregnancy-Induced Hypertension Preeclampsia Proteinuria Sulfosalicylic Acid Test |
| description |
ABSTRACT: To determine the reliability and accuracy of the sulfosalicylic acid test in the fast detection and semi-quantitative analysis of proteinuria. Methods: Prospective, descriptive study at Hospital Universitario San Vicente de Paúl in Medellín, Colombia. Ninety eight women with proteinuria and 129 without it were included. Turbidity test with sulfosalicylic acid was compared to 24-hour-proteinuria. Results: The likelihood ratios (LR) for turbidity test results of 1+, 2+, 3+, 4+, and 5+ were 0.4, 0.7, 3.4, 6.7, and 39.1, respectively. Interclass correlation between the three evaluators of turbidity was 0.966. With the cut point set at 4+, sensitivity was 41.1% (CI 95%: 30.6-51.5), and specificity was 97.7% (CI 95%: 94.7-100). In hypertensive patients, positive predictive value was 95% (CI 95%: 87-100) and negative predictive value was 53.3% (CI 95%: 42.5-64). Conclusion: Turbidity test is an easy, fast, cheap, and reproducible analysis. Because of its high specificity it is ideal to study pregnant women, particularly those with hypertension, for proteinuria. |
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2011 |
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2011 |
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2019-12-20T17:22:15Z |
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2019-12-20T17:22:15Z |
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Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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Velásquez Penagos JA, Zuleta Tobón JJ, López Jaramillo JD, Gómez Marulanda NL, Gómez Gallego J. Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy. Iatreia. 2011 Sep-Nov;24(3): 259-266. |
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0121-0793 |
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http://hdl.handle.net/10495/12672 |
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2011-7965 |
| identifier_str_mv |
Velásquez Penagos JA, Zuleta Tobón JJ, López Jaramillo JD, Gómez Marulanda NL, Gómez Gallego J. Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy. Iatreia. 2011 Sep-Nov;24(3): 259-266. 0121-0793 2011-7965 |
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http://hdl.handle.net/10495/12672 |
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eng |
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eng |
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Iatreia |
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266 |
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3 |
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24 |
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Iatreia |
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https://creativecommons.org/licenses/by-nc-sa/4.0/ |
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https://creativecommons.org/licenses/by-nc-sa/2.5/co/ |
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Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) |
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info:eu-repo/semantics/openAccess |
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Universidad de Antioquia, Facultad de Medicina |
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Medellín, Colombia |
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Universidad de Antioquia |
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Velásquez Penagos, Jesús ArnulfoZuleta Tobón, John JairoLópez Jaramillo, José DuvánGómez Marulanda, Natalia LucíaGómez Gallego, Jáder de JesúsNacer, Salud Sexual y Reproductiva2019-12-20T17:22:15Z2019-12-20T17:22:15Z2011Velásquez Penagos JA, Zuleta Tobón JJ, López Jaramillo JD, Gómez Marulanda NL, Gómez Gallego J. Use of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancy. Iatreia. 2011 Sep-Nov;24(3): 259-266.0121-0793http://hdl.handle.net/10495/126722011-7965ABSTRACT: To determine the reliability and accuracy of the sulfosalicylic acid test in the fast detection and semi-quantitative analysis of proteinuria. Methods: Prospective, descriptive study at Hospital Universitario San Vicente de Paúl in Medellín, Colombia. Ninety eight women with proteinuria and 129 without it were included. Turbidity test with sulfosalicylic acid was compared to 24-hour-proteinuria. Results: The likelihood ratios (LR) for turbidity test results of 1+, 2+, 3+, 4+, and 5+ were 0.4, 0.7, 3.4, 6.7, and 39.1, respectively. Interclass correlation between the three evaluators of turbidity was 0.966. With the cut point set at 4+, sensitivity was 41.1% (CI 95%: 30.6-51.5), and specificity was 97.7% (CI 95%: 94.7-100). In hypertensive patients, positive predictive value was 95% (CI 95%: 87-100) and negative predictive value was 53.3% (CI 95%: 42.5-64). Conclusion: Turbidity test is an easy, fast, cheap, and reproducible analysis. Because of its high specificity it is ideal to study pregnant women, particularly those with hypertension, for proteinuria.RESUMEN: Determinar la confiabilidad de la prueba del ácido sulfosalicílico en la detección rápida y semicuantificación de la proteinuria. Métodos: estudio descriptivo, prospectivo llevado a cabo en el Hospital Universitario San Vicente de Paúl, Medellín, Colombia. Se incluyeron 98 mujeres gestantes con proteinuria y 129 sin proteinuria. La prueba de turbidez con ácido sulfosalicílico se comparó con la medición de proteinuria en 24 horas. Resultados: los coeficientes de probabilidad (likelihood ratio) para los resultados de la prueba fueron los siguientes: 1+ = 0,4; 2+: = 0,7; 3+ = 3,4; 4+ = 6,7 y 5+ = 39,1. La correlación entre los tres evaluadores de la turbidez fue 0,966. Con un punto de corte de 4+ la sensibilidad fue 41,1% (IC 95%: 30,6- 51,5), la especificidad fue 97,7% (IC 95%: 94,7-100). Cuando la prueba se aplicó solamente a las pacientes hipertensas el valor predictivo positivo fue 95% (IC 95%: 87-100) y el valor predictivo negativo fue 53,3% (IC 95%: 42,5-64). Conclusiones: la prueba de turbidez con ácido sulfosalicílico es fácil, rápida, económica y reproducible. Por su baja sensibilidad no es útil como método de tamización pero por su alta especificidad es ideal para la confirmación rápida de proteinuria en las gestantes hipertensas.8application/pdfengUniversidad de Antioquia, Facultad de MedicinaMedellín, Colombiahttps://creativecommons.org/licenses/by-nc-sa/4.0/https://creativecommons.org/licenses/by-nc-sa/2.5/co/Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Pregnancy-Induced HypertensionPreeclampsiaProteinuriaSulfosalicylic Acid TestUse of sulfosalicylic acid in the detection of proteinuria and its application to hypertensive problems in pregnancyUso del ácido sulfosalicílico para la detección de proteinuria y su aplicación a problemas de hipertensión en el embarazoArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionIatreia266324IatreiaPublicationORIGINALVelásquezJesús_2011_SulfosalicylicProteinuriaPregnancy.pdfVelásquezJesús_2011_SulfosalicylicProteinuriaPregnancy.pdfArtículo de investigaciónapplication/pdf280059https://bibliotecadigital.udea.edu.co/bitstreams/c09402d1-6bf2-4409-80cb-7b6c10a52bd9/download5105c463e929f18842428d509639a39dMD51trueAnonymousREADCC-LICENSElicense_urllicense_urltext/plain; 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