Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review

ABSTRACT: Interesting health benefits have been attributed to the intake of conjugated linoleic acid, CLA (C18:2 cis9, trans-11), which is the main isomer of linoleic acid, and is present in bovine milk. Among those benefits are: cancer prevention, diminished risk for the onset of type II diabetes a...

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Autores:
Olivera Ángel, Martha
Castillo Vargas, Julián Andrés
Pabón, Martha Lucía
Carulla Formaguera, Juan Evangelista
Tipo de recurso:
Review article
Fecha de publicación:
2010
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/8348
Acceso en línea:
http://hdl.handle.net/10495/8348
Palabra clave:
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openAccess
License
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
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network_acronym_str UDEA2
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repository_id_str
dc.title.spa.fl_str_mv Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
dc.title.alternative.spa.fl_str_mv Papel de la estearoil CoA desaturasa sobre la variabilidad en los niveles de ácido linoléico conjugado en la leche bovina : revisión
title Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
spellingShingle Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
title_short Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
title_full Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
title_fullStr Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
title_full_unstemmed Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
title_sort Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : review
dc.creator.fl_str_mv Olivera Ángel, Martha
Castillo Vargas, Julián Andrés
Pabón, Martha Lucía
Carulla Formaguera, Juan Evangelista
dc.contributor.author.none.fl_str_mv Olivera Ángel, Martha
Castillo Vargas, Julián Andrés
Pabón, Martha Lucía
Carulla Formaguera, Juan Evangelista
description ABSTRACT: Interesting health benefits have been attributed to the intake of conjugated linoleic acid, CLA (C18:2 cis9, trans-11), which is the main isomer of linoleic acid, and is present in bovine milk. Among those benefits are: cancer prevention, diminished risk for the onset of type II diabetes and cardiovascular disease, modulation of the immune response, and reduction of preeclampsia risk in primigravid women. Although an adequate nutrition of cows has permitted to increase the amount of CLA in their milk, there is variation in CLA concentrations among cows consuming the same diet. It has been suggested that this variation is due either to changes in the activity of stearoyl CoA desaturase (SCD), changes in the gene expression, or to alterations in the ruminal process of biohydrogenation. Research conducted in semimembranosus muscle and subcutaneous adipose tissue of cattle suggests there are two isoforms of SCD.
publishDate 2010
dc.date.issued.none.fl_str_mv 2010
dc.date.accessioned.none.fl_str_mv 2017-09-26T22:02:30Z
dc.date.available.none.fl_str_mv 2017-09-26T22:02:30Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.spa.fl_str_mv Castillo JA, Pabón ML, Olivera M, Carulla JE. Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk. Review. Rev. Colomb. Cienc. Pecu. 2010; 23(4):493-500.
dc.identifier.issn.none.fl_str_mv 0120-0690
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/8348
dc.identifier.eissn.none.fl_str_mv 2256-2958
identifier_str_mv Castillo JA, Pabón ML, Olivera M, Carulla JE. Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk. Review. Rev. Colomb. Cienc. Pecu. 2010; 23(4):493-500.
0120-0690
2256-2958
url http://hdl.handle.net/10495/8348
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Rev. Colomb. Cienc. Pecu.
dc.rights.*.fl_str_mv Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
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dc.publisher.spa.fl_str_mv Universidad de Antioquia, Facultad de Ciencias Agrarias
dc.publisher.group.spa.fl_str_mv Biogénesis
dc.publisher.place.spa.fl_str_mv Medellín, Colombia
institution Universidad de Antioquia
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spelling Olivera Ángel, MarthaCastillo Vargas, Julián AndrésPabón, Martha LucíaCarulla Formaguera, Juan Evangelista2017-09-26T22:02:30Z2017-09-26T22:02:30Z2010Castillo JA, Pabón ML, Olivera M, Carulla JE. Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk. Review. Rev. Colomb. Cienc. Pecu. 2010; 23(4):493-500.0120-0690http://hdl.handle.net/10495/83482256-2958ABSTRACT: Interesting health benefits have been attributed to the intake of conjugated linoleic acid, CLA (C18:2 cis9, trans-11), which is the main isomer of linoleic acid, and is present in bovine milk. Among those benefits are: cancer prevention, diminished risk for the onset of type II diabetes and cardiovascular disease, modulation of the immune response, and reduction of preeclampsia risk in primigravid women. Although an adequate nutrition of cows has permitted to increase the amount of CLA in their milk, there is variation in CLA concentrations among cows consuming the same diet. It has been suggested that this variation is due either to changes in the activity of stearoyl CoA desaturase (SCD), changes in the gene expression, or to alterations in the ruminal process of biohydrogenation. Research conducted in semimembranosus muscle and subcutaneous adipose tissue of cattle suggests there are two isoforms of SCD.RESUMEN: Al isómero mayoritario del ácido linoléico, C18:2 cis-9, trans-11 (Ácido Linoléico Conjugado, ALC) en la leche bovina, se le han atribuido propiedades benéficas para la salud humana, entre las que está su efecto en la prevención del cáncer, disminución de los factores de riesgo para la presentacion de diabetes tipo II y de enfermendades cardiovasculares, modulación de la respuesta inmune como también, en la reducción del riesgo de preeclamsia en mujeres primigrávidas. Aunque se ha logrado elevar la concentración de ALC en leche mediante sistemas de alimentación adecuados, existe variabilidad en su concentración para individuos de una misma especie y sometidos a la misma alimentación. Para explicar dicha variabilidad, se ha sugerido que esta se debe a cambios en la actividad de la Estearoil CoA Desaturasa (ECD), de la expresión genética diferencial o a alteraciones en el proceso de biohidrogenación ruminal. Trabajos realizados en músculo semimembranoso y tejido adiposo subcutáneo en bovinos, sugieren la presencia de dos isoformas de la ECD.COL0066561application/pdfengUniversidad de Antioquia, Facultad de Ciencias AgrariasBiogénesisMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVArtículo de revisiónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Role of stearoyl CoA desaturase on conjugated Linoleic acid concentration in bovine milk : reviewPapel de la estearoil CoA desaturasa sobre la variabilidad en los niveles de ácido linoléico conjugado en la leche bovina : revisiónRev. Colomb. Cienc. Pecu.Revista Colombiana de Ciencias Pecuarias493500234CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://bibliotecadigital.udea.edu.co/bitstream/10495/8348/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/8348/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/8348/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/8348/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD55ORIGINALOliveraMartha_2010_RoleStearoyl_CoAconcentration Bovine.pdfOliveraMartha_2010_RoleStearoyl_CoAconcentration Bovine.pdfArtículo de Revisiónapplication/pdf765686http://bibliotecadigital.udea.edu.co/bitstream/10495/8348/1/OliveraMartha_2010_RoleStearoyl_CoAconcentration%20Bovine.pdfd19326630d1c32f29cc0c3c1fb47e2eeMD5110495/8348oai:bibliotecadigital.udea.edu.co:10495/83482021-05-21 20:29:50.59Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.coTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=