Adherence to human lung microvascular endothelial cells (HMVEC-L) of Plasmodium vivax isolates from Colombia

ABSTARCT: For years Plasmodium vivax has been considered the cause of benign malaria. Nevertheless, it has been observed that this parasite can produce a severe disease comparable to Plasmodium falciparum. It has been suggested that some physiopathogenic processes might be shared by these two specie...

Full description

Autores:
De las salas, Briegel
Segura, Cesar
Pabón Vidal, Adriana Lucía
Lopes, Stefanie CP
Costa, Fabio TM
Blair Trujillo, Silvia
Tipo de recurso:
Article of investigation
Fecha de publicación:
2013
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/7894
Acceso en línea:
http://hdl.handle.net/10495/7894
Palabra clave:
Cytoadherence
Plasmodium vivax
Malaria
ICAM-1
Microvascular line of human lung endothelium Colombia
Rights
openAccess
License
Atribución 2.5
Description
Summary:ABSTARCT: For years Plasmodium vivax has been considered the cause of benign malaria. Nevertheless, it has been observed that this parasite can produce a severe disease comparable to Plasmodium falciparum. It has been suggested that some physiopathogenic processes might be shared by these two species, such as cytoadherence. Recently, it has been demonstrated that P. vivax-infected erythrocytes (Pv-iEs) have the capacity to adhere to endothelial cells, in which intercellular adhesion molecule-1 (ICAM-1) seems to be involved in this process.