Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo
ABSTRACT: In this study we present the procedure to obtain synthetic hydroxyapatite (HA) from ammonium phosphate and calcium nitrate sources. Cellulose fibers were incorporated with the purpose to achieve a good crystallization of HA and combustion of the cellulose was performed in order to produce...
- Autores:
-
Riaño Benavides, Carlos Humberto
Echavarría Velásquez, Alejandro Iván
Gloria E., Ramírez J.
Escobar Luján, Iván Guillermo
Cardona, Jhon J.
Giraldo Ramírez, Adriana Estella
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 1999
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- spa
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/7190
- Acceso en línea:
- http://hdl.handle.net/10495/7190
- Palabra clave:
- Conejos
Ortopedia
- Rights
- openAccess
- License
- Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
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| dc.title.spa.fl_str_mv |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| title |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| spellingShingle |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo Conejos Ortopedia |
| title_short |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| title_full |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| title_fullStr |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| title_full_unstemmed |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| title_sort |
Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo |
| dc.creator.fl_str_mv |
Riaño Benavides, Carlos Humberto Echavarría Velásquez, Alejandro Iván Gloria E., Ramírez J. Escobar Luján, Iván Guillermo Cardona, Jhon J. Giraldo Ramírez, Adriana Estella |
| dc.contributor.author.none.fl_str_mv |
Riaño Benavides, Carlos Humberto Echavarría Velásquez, Alejandro Iván Gloria E., Ramírez J. Escobar Luján, Iván Guillermo Cardona, Jhon J. Giraldo Ramírez, Adriana Estella |
| dc.subject.none.fl_str_mv |
Conejos Ortopedia |
| topic |
Conejos Ortopedia |
| description |
ABSTRACT: In this study we present the procedure to obtain synthetic hydroxyapatite (HA) from ammonium phosphate and calcium nitrate sources. Cellulose fibers were incorporated with the purpose to achieve a good crystallization of HA and combustion of the cellulose was performed in order to produce a porous-like material. The X-ray diffraction analysis (XRD) showed a high proportion of HA with small quantities of tricalcium and tetracalcium phosphates. Coral samples treated with ammonium phosphate by a hydrothermal procedure or coral samples pre-heated at 650 and 1000 °C submerged in ammonium phosphates and later on treated at 1050 °C by a pyrothermal procedure were also evaluated by XRD. The hydrothermal technique did not produce decomposition of the typical aragonite frame of the coral, whereas the pyrothermal technique did not produce any quantity of HA. Finally, a good integration of the HA was observed when HA was implanted to tibial bone in dogs; remodeling and reparation were optimal and evolved according to normal processes. However, the animals implanted with coralline showed necrosis, lysis and severe inflammatory reactions at the implantation sites. These results indicate that it is not possible obtain HA from coral under the experimental conditions here evaluated and that coralline did not behave as a good biocompatible material for implants. |
| publishDate |
1999 |
| dc.date.issued.none.fl_str_mv |
1999 |
| dc.date.accessioned.none.fl_str_mv |
2017-05-10T18:43:28Z |
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2017-05-10T18:43:28Z |
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info:eu-repo/semantics/article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Artículo de investigación |
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Riaño C, Echavarría A, Ramírez G, Escobar I, Cardona JJ, Giraldo AE. Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo. Rev. colomb. cienc. pecu. 1999,12 (2):97–107. |
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0120-0690 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/7190 |
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2256-2958 |
| identifier_str_mv |
Riaño C, Echavarría A, Ramírez G, Escobar I, Cardona JJ, Giraldo AE. Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo. Rev. colomb. cienc. pecu. 1999,12 (2):97–107. 0120-0690 2256-2958 |
| url |
http://hdl.handle.net/10495/7190 |
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spa |
| language |
spa |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Rev. Colomb. Cienc. Pecu. |
| dc.rights.*.fl_str_mv |
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) |
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info:eu-repo/semantics/openAccess |
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Universidad de Antioquia, Facultad de Ciencias Agrarias |
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Medellín, Colombia |
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Universidad de Antioquia |
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Riaño Benavides, Carlos HumbertoEchavarría Velásquez, Alejandro IvánGloria E., Ramírez J.Escobar Luján, Iván GuillermoCardona, Jhon J.Giraldo Ramírez, Adriana Estella2017-05-10T18:43:28Z2017-05-10T18:43:28Z1999Riaño C, Echavarría A, Ramírez G, Escobar I, Cardona JJ, Giraldo AE. Características osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivo. Rev. colomb. cienc. pecu. 1999,12 (2):97–107.0120-0690http://hdl.handle.net/10495/71902256-2958ABSTRACT: In this study we present the procedure to obtain synthetic hydroxyapatite (HA) from ammonium phosphate and calcium nitrate sources. Cellulose fibers were incorporated with the purpose to achieve a good crystallization of HA and combustion of the cellulose was performed in order to produce a porous-like material. The X-ray diffraction analysis (XRD) showed a high proportion of HA with small quantities of tricalcium and tetracalcium phosphates. Coral samples treated with ammonium phosphate by a hydrothermal procedure or coral samples pre-heated at 650 and 1000 °C submerged in ammonium phosphates and later on treated at 1050 °C by a pyrothermal procedure were also evaluated by XRD. The hydrothermal technique did not produce decomposition of the typical aragonite frame of the coral, whereas the pyrothermal technique did not produce any quantity of HA. Finally, a good integration of the HA was observed when HA was implanted to tibial bone in dogs; remodeling and reparation were optimal and evolved according to normal processes. However, the animals implanted with coralline showed necrosis, lysis and severe inflammatory reactions at the implantation sites. These results indicate that it is not possible obtain HA from coral under the experimental conditions here evaluated and that coralline did not behave as a good biocompatible material for implants.RESUMEN: Se presenta el procedimiento de obtención de hidroxiapatita (HA) sintética, Ca10(PO4)6(OH)2 a partir de fosfato de amonio y nitrato de calcio. Se incorporan fibras de celulosa, con el propósito de obtener una buena cristalización de HA y combustión de la celulosa formando un material poroso. Los análisis muestran alta proporción de HA y menor cantidad de fosfatos tetracálcico y tricálcico. Muestras de coral tratadas con fosfato de amonio (vía hidrotérmica) y muestras de coral precalentadas a 650 y 1000 °C, sumergidas en fosfato de amonio y posteriormente tratadas a 1050 °C (vía pirotérmica) fueron evaluadas mediante difracción de rayos X (DRX). Por la vía hidrotérmica no se obtuvo descomposición apreciable de la red de aragonito típica del coral y la vía pirotérmica propuesta, exhibe una baja o nula cantidad de HA. Los resultados indican que no es posible obtener HA a partir del coral bajo las condiciones experimentales evaluadas y que la coralina no se comporta como un material biocompatible para obtener regeneración ósea. Por último, al colocar injertos aloplásticos de HA, se observó buena integración de estos al hueso; los procesos de remodelación y reparación ósea fueron adecuados y evolucionaron de forma normal. Sin embargo, el grupo que recibió como injerto aloplástico la coralina presentó necrosis y lisis del hueso con marcada reacción inflamatoria.application/pdfspaUniversidad de Antioquia, Facultad de Ciencias AgrariasMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/ConejosOrtopediaCaracterísticas osteoconductoras de la hidroxiapatita sintética y la derivada de corales marinos injertadas en conejos. Análisis descriptivoRev. Colomb. Cienc. Pecu.Revista Colombiana de Ciencias Pecuarias97107122ORIGINALRiaño_C_1999_Características_osteoconductoras_hidroxiapatita_sintética_injertadas.pdfRiaño_C_1999_Características_osteoconductoras_hidroxiapatita_sintética_injertadas.pdfArtículo de investigaciónapplication/pdf2449668http://bibliotecadigital.udea.edu.co/bitstream/10495/7190/1/Ria%c3%b1o_C_1999_Caracter%c3%adsticas_osteoconductoras_hidroxiapatita_sint%c3%a9tica_injertadas.pdf0bbb1a3bc4a8233759b06c3316812664MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://bibliotecadigital.udea.edu.co/bitstream/10495/7190/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/7190/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://bibliotecadigital.udea.edu.co/bitstream/10495/7190/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/7190/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5510495/7190oai:bibliotecadigital.udea.edu.co:10495/71902021-05-21 20:26:18.981Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |