The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study)
- Autores:
-
Gagliardi B, Rosa
Martínez A, Diana
Tellechea H, Beatriz
Sitjar Q, Pedro
Llambí D, Silvia
Arruga L, María
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2015
- Institución:
- Universidad de Córdoba
- Repositorio:
- Repositorio Institucional Unicórdoba
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unicordoba.edu.co:ucordoba/5290
- Acceso en línea:
- https://repositorio.unicordoba.edu.co/handle/ucordoba/5290
https://doi.org/10.21897/rmvz.78
- Palabra clave:
- Dogs
ivermectine
P-glycoprotein
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-sa/4.0/
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The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| dc.title.translated.eng.fl_str_mv |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| title |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| spellingShingle |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) Dogs ivermectine P-glycoprotein |
| title_short |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| title_full |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| title_fullStr |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| title_full_unstemmed |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| title_sort |
The search for the mdr1-1Δ mutation of the MDR1 gene in four canine breeds in Uruguay (preliminary study) |
| dc.creator.fl_str_mv |
Gagliardi B, Rosa Martínez A, Diana Tellechea H, Beatriz Sitjar Q, Pedro Llambí D, Silvia Arruga L, María |
| dc.contributor.author.spa.fl_str_mv |
Gagliardi B, Rosa Martínez A, Diana Tellechea H, Beatriz Sitjar Q, Pedro Llambí D, Silvia Arruga L, María |
| dc.subject.spa.fl_str_mv |
Dogs ivermectine P-glycoprotein |
| topic |
Dogs ivermectine P-glycoprotein |
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2015 |
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2015-01-07 00:00:00 2022-06-17T20:08:35Z |
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2015-01-07 00:00:00 2022-06-17T20:08:35Z |
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2015-01-07 |
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Merola V, Khan S, Gwaltney-Brant S. Ivermectin toxicosis in dogs: A restrospective study. J Am Anim Hosp Assoc 2009; 45 (3):106-111. http://dx.doi.org/10.5326/0450106 Gramer I, Leidolf R, , DÓ§ring B, Klintzsch S, Krämer E-M, Yalcin E, Petzinger E, Geyer J. Breed distribution of the nt230 (del4) MDR1 mutation in dogs. Vet J 2011; 189 (1):67-71. http://dx.doi.org/10.1016/j.tvjl.2010.06.012 Geyer J, Klintzsch S, Meerkamp K, Wöhlke A, Distl O, Moritz A, Petzinger E . Detection of the nt230 (del4) MDR1 mutation in White Swiss Shepherd dogs: case reports of doramectin toxicosis, breed predisposition, and microsatellite analysis. J Vet Pharmacol Therap 2007; 30 (5):482-485. http://dx.doi.org/10.1111/j.1365-2885.2007.00885.x Roulet A, Puel O, Gesta S, Lepage J-F, Drag M, Soll M, Alvinerie M, Pineau T. MDR1-deficient genotype in Collie dog hypersensitive to the Pglycoprotein substrate ivermectin. European J of Pharmacol 2003; 460 (2-3):85-91. http://dx.doi.org/10.1016/S0014-2999(02)02955-2 Mealey KL, Bentjen SA, Gay JM, Canthor GH. Ivermectin sensitivity in collies is associated with a deletion mutation of the MDR1 gene. Pharmacogenetics 2001; 11 (8):727-733. http://dx.doi.org/10.1097/00008571-200111000-00012 Fraga J, Rodríguez J, Fuentes O, Castex M, Fernández-Calienes A. Comparación entre 5 métodos para la extracción de ADN de triatomíneos: su utilización en la técnica de ADN polimórfico amplificado al azar Rev Cubana Med Trop 2004; 56 (3):208-13. Mealey KL. Farmacogenetica. Clin Vet NA Med Peq Anim 2006; 36 (5):961-973. Neff MW, Robertson KR, Wong AK, Safra N, Broman KW, Slatkin M, Mealey KL, Pedersen NC. Breed distribution and history of canine mdr1-1Δ a pharmacogenetic mutation that marks the emergence of breed from the collie lineage. Proc Nat Acad Sci 2004; 101 (32):11725-11730. http://dx.doi.org/10.1073/pnas.0402374101 Bissonnette S, Paradis M, Daneau I, Silverside DW. The ABCB1-1Δ mutation is not responsible for subchronic neurotoxicity seen in dogs of noncollie breeds following macrocyclic lactone treatment for generalized demodicosis. Vet Dermatol 2008; 20(1):60-66. http://dx.doi.org/10.1111/j.1365-3164.2008.00731.x Geyer J, DÓ§ring B, Godoy JR, Leidolf R, Moritz A, Petzinger E. Frecuency of the nt230 (del4) MDR1 mutation in Collies and related dog breeds in Germany. J Vet Pharmacol Therap 2005; 28 (6):545-551. http://dx.doi.org/10.1111/j.1365-2885.2005.00692.x Gagliardi R, García C, Llambí S, Arruga MV. Analysis of mdr1-1Δ mutation of MDR1 gene in the "Cimarron Uruguayo" dog. Rev MVZ Córdoba 2013; 18(2):3480-3483. Gagliardi R. Estudios geneticos en caninos de raza Cimarron Uruguayo (Canis familiaris). [Tesis de Maestría]. Montevideo: Universidad de la República, Programa de Desarrollo de las Ciencias Básicas (PEDEClBA); 2009. Tomiyasu H, Goto-Koshino Y, Fujino Y, Ohno K, Tsujimoto H. Epigenetic regulation of the ABCB1 gene in drug-sensitive and drug-resistant lymphoid tumour cell lines obtained from canine patients. Vet J 2014; 199 (1): 103-109. http://dx.doi.org/10.1016/j.tvjl.2013.10.022 |
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