Teratología conductual: un apasionante campo de trabajo transdisciplinar
Desde el impresionante precedente de la tragedia de la Talidomida, un ansiolítico, hipnótico y antiemético usado en el primer trimestre de la gestación que causó graves malformaciones cardíacas, renales, digestivas, oftálmicas auditivas y ausencia total o parcial de los miembros superiores/inferiore...
- Autores:
-
Santacruz-Ortega, María del Pilar
- Tipo de recurso:
- Part of book
- Fecha de publicación:
- 2022
- Institución:
- Universidad Católica de Colombia
- Repositorio:
- RIUCaC - Repositorio U. Católica
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- spa
- OAI Identifier:
- oai:repository.ucatolica.edu.co:10983/30017
- Palabra clave:
- FETO-MALFORMACIONES
SISTEMA NERVIOSO-MALFORMACIONES
150 - Psicología
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- openAccess
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- Derechos Reservados - Universidad Católica de Colombia, 2022
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Teratología conductual: un apasionante campo de trabajo transdisciplinar |
title |
Teratología conductual: un apasionante campo de trabajo transdisciplinar |
spellingShingle |
Teratología conductual: un apasionante campo de trabajo transdisciplinar FETO-MALFORMACIONES SISTEMA NERVIOSO-MALFORMACIONES 150 - Psicología |
title_short |
Teratología conductual: un apasionante campo de trabajo transdisciplinar |
title_full |
Teratología conductual: un apasionante campo de trabajo transdisciplinar |
title_fullStr |
Teratología conductual: un apasionante campo de trabajo transdisciplinar |
title_full_unstemmed |
Teratología conductual: un apasionante campo de trabajo transdisciplinar |
title_sort |
Teratología conductual: un apasionante campo de trabajo transdisciplinar |
dc.creator.fl_str_mv |
Santacruz-Ortega, María del Pilar |
dc.contributor.author.none.fl_str_mv |
Santacruz-Ortega, María del Pilar |
dc.subject.armarc.none.fl_str_mv |
FETO-MALFORMACIONES SISTEMA NERVIOSO-MALFORMACIONES |
topic |
FETO-MALFORMACIONES SISTEMA NERVIOSO-MALFORMACIONES 150 - Psicología |
dc.subject.ddc.none.fl_str_mv |
150 - Psicología |
description |
Desde el impresionante precedente de la tragedia de la Talidomida, un ansiolítico, hipnótico y antiemético usado en el primer trimestre de la gestación que causó graves malformaciones cardíacas, renales, digestivas, oftálmicas auditivas y ausencia total o parcial de los miembros superiores/inferiores, entre otras, y a partir de trabajos como (DeSesso, 2019; Moore & Persaud, 2013; Papaseit et al., 2013), y la publicación del minucioso trabajo de Werboff & Gottlieb (1963) se estableció que las drogas de consumo materno durante la gestación –tanto las prescritas como las que no– tienen unos potentes efectos teratogénicos, es decir, producen malformaciones congénitas durante el desarrollo del infante. Estas malformaciones pueden darse en diferentes órganos o tejidos; y cuando ocurren en el sistema nervioso no son tan evidentes, y se reflejan en alteraciones del comportamiento que se pueden manifestar en la infancia, la adolescencia o más tardíamente. Cuando las malformaciones congénitas se observan en el comportamiento, pertenecen al campo de la Teratología Conductual o Teratología Neuroconductual (Minnes et al., 2014; Werboff & Gottlieb, 1963). |
publishDate |
2022 |
dc.date.issued.none.fl_str_mv |
2022-12 |
dc.date.accessioned.none.fl_str_mv |
2023-01-25T22:02:35Z |
dc.date.available.none.fl_str_mv |
2023-01-25T22:02:35Z |
dc.type.none.fl_str_mv |
Capítulo - Parte de Libro |
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http://purl.org/coar/resource_type/c_3248 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Text |
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info:eu-repo/semantics/bookPart |
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http://purl.org/redcol/resource_type/CAP_LIB |
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info:eu-repo/semantics/publishedVersion |
format |
http://purl.org/coar/resource_type/c_3248 |
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publishedVersion |
dc.identifier.citation.none.fl_str_mv |
Santacruz-Ortega, M. P. (2022). Teratología conductual: un apasionante campo de trabajo transdisciplinar. En Alejo-Castañeda, I. E., & Cobo-Charry, M. F. (Eds.) (2022). Investigación en psicología: aplicaciones e intervenciones II (pp. 193-214). Editorial Universidad Católica de Colombia. https://doi.org/10.14718/9786287554320.2022.9 |
dc.identifier.eisbn.none.fl_str_mv |
978-628-7554-32-0 |
dc.identifier.isbn.none.fl_str_mv |
978-628-7554-31-3 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10983/30017 |
dc.identifier.url.none.fl_str_mv |
https://doi.org/10.14718/9786287554320.2022.9 |
identifier_str_mv |
Santacruz-Ortega, M. P. (2022). Teratología conductual: un apasionante campo de trabajo transdisciplinar. En Alejo-Castañeda, I. E., & Cobo-Charry, M. F. (Eds.) (2022). Investigación en psicología: aplicaciones e intervenciones II (pp. 193-214). Editorial Universidad Católica de Colombia. https://doi.org/10.14718/9786287554320.2022.9 978-628-7554-32-0 978-628-7554-31-3 |
url |
https://hdl.handle.net/10983/30017 https://doi.org/10.14718/9786287554320.2022.9 |
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spa |
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dc.relation.citationendpage.none.fl_str_mv |
240 |
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dc.relation.ispartof.none.fl_str_mv |
Alejo-Castañeda, I. E., & Cobo-Charry, M. F. (Eds.) (2022). Investigación en psicología: aplicaciones e intervenciones II. Editorial Universidad Católica de Colombia. https://doi.org/10.14718/9786287554320.2022 |
dc.relation.ispartofbook.none.fl_str_mv |
Investigación en psicología: aplicaciones e intervenciones II |
dc.relation.ispartofseries.none.fl_str_mv |
Colección Logos Vestigium; no. 17 |
dc.relation.references.none.fl_str_mv |
Abel, E. (2012). Behavioral teratogenesis and behavioral mutagenesis: A primer in abnormal development. Springer Science & Business Media. Alwan S, Chambers CD. (2015). Identifying Human Teratogens: An Update. J Pediatr Genet. 4(2), 39-41. https:/doi.org/10.1055/s-0035-1556745 Alwan, S., & Bérard, A. (2019). Epidemiology of the Use of Psychotropic Drugs in Pregnant and Nursing Women. In Perinatal Psychopharmacology (pp. 3-16). Springer, Cham. https:// doi.org/10.1007/978-3-319-92919-4_1 Bell, M. F., Bayliss, D. M., Glauert, R., Harrison, A., & Ohan, J. L. (2019). Children of parents who have been hospitalised with psychiatric disorders are at risk of poor school readiness. Epidemiology and Psychiatric Sciences, 28(5), 508-520. 10.1017/S2045796018000148 Blanco, S. y Santacruz-Ortega, MDP. (s.f). Impacto de la exposición prenatal a cocaína en la conducta emocional. (artículo en preparación). Campbell, J. O., Bliven, T. D., Silveri, M. M., Snyder, K. J., & Spear, L. P. (2000). Effects of prenatal cocaine on behavioral adaptation to chronic stress in adult rats. Neurotoxicology and Teratology, 22(6), 845-850. https://doi.org/10.1016/S0892-0362(00)00104-5 Center for Behavioral Health Statistics and Quality (2014). 2013 National Survey on Drug Use and Health: Mental Health Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD. https://www.samhsa.gov/data/sites/default/files/ 2013MHDetTabs/NSDUH-MHDetTabs2013.pdf Center for Behavioral Health Statistics and Quality. (2016). 2014 National Survey on Drug Use and Health: Methodological Resource Book (Section 13, Statistical Inference Report) Substance Abuse and Mental Health Services Administration, Rockville, MD. http:// www.samhsa.gov/data/sites/default/files/NSDUHmrbStatInference2014.pdf Chaplin, T.M, Visconti K.J., Molfese, P.J., Susman, E.J., Klein, L.C., Sinha, R. y Mayes, L.C. (2014). Prenatal cocaine exposure differentially affects stress responses in girls and boys: Associations with future substance use. Development and Psychopathology, 18, 1-8. 10.1017/S0954579414000716 Chasnoff, I. J. (Ed.). (1986). Drug Use in Pregnancy: Mother and Child: Mother and Child. Springer Science & Business Media. Chasnoff, I. J. (Ed.). (2012). Drugs, alcohol, pregnancy, and parenting. Springer Science & Business Media. Cook, J. L., Green, C. R., de la Ronde, S., Dell, C. A., Graves, L., Ordean, A., ... & Wong, S. (2017). Epidemiology and effects of substance use in pregnancy. Journal of Obstetrics and Gynecology Canada, 39(10), 906-915. https://doi.org/10.1016/j.jogc.2017.07.005 Cortes, L., Almeida, L., Sabra, S., Muniesa, M., Busardo, F. P., Garcia-Algar, O., & Gomez- -Roig, M. D. (2018). Maternal hair and neonatal meconium to assess gestational consumption and prenatal exposure to drugs of abuse and psychoactive drugs. Current Pharmaceutical Biotechnology, 19(2), 136-143. https://doi.org/10.2174/1389201019666 180405163612 Davis, E. P., Hankin, B. L., Glynn, L. M., Head, K., Kim, D. J., & Sandman, C. A. (2020). Prenatal maternal stress, child cortical thickness, and adolescent depressive symptoms. Child Development, 91(2), e432-e450. https://doi.org/10.1111/cdev.13252 DeSesso, J. M. (2019). The arrogance of teratology: A brief chronology of attitudes throughout history. Birth Defects Research, 111(3), 123-141. https://doi.org/10.1002/bdr2.1422 Donaldson, S. T., Ravenelle, R., & Difronzo, M. (2017). Prenatal Cocaine Insult in Rats: Enduring Effects on Stress, GABA Neuron Morphology and Receptor Sensitivity. J Toxicol Pharmacol, 1, 010 Ekvall, S., Eckvall, V., & Fowles, E. (2005). Pediatric nutrition in chronic diseases and developmental disorders: Prevention, assessment, and treatment, and Edition. In S. W. Ekvall & V. K. Ekvall (Eds.), Prenatal Growth in Pregnancy (pp. 3–16). New York: Oxford University Press. Felipe, A. (2005). Introducción a la teratología: el estudio de las malformaciones congénitas en medicina veterinaria. http://www.revistaciencias.com/publicaciones/EpZypupFZuvapWVpML. php Finger, B., Schuetze, P. y Eiden, R. (2015). Behavior problems among cocaine-exposed children: Role of physiological regulation and parenting. Drug & Alcohol Dependence, 146, e278. 10.1016/j.ntt.2014.01.001 File, S. E., & Wardill, A. G. (1975). Validity of head-dipping as a measure of exploration in a modified hole-board. Psychopharmacology, 44(1), 53-59. https://doi.org/10.1007/ BF00421184 Lister, R. G. (1987). The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology, 92(2), 180-185. https://doi.org/10.1007/BF00177912 Fried, P. A. (2002). Conceptual issues in behavioral teratology and their application in determining long-term sequelae of prenatal marihuana exposure. Journal of Child Psychology and Psychiatry, 43(1), 81-102. https://doi.org/10.1111/1469-7610.00005 Fried, P. A., Watkinson, B., & Gray, R. (2012). Neurocognitive consequences of marihuana—a comparison with pre-drug performance. Neurotoxicology and Teratology, 27(2), 231- 239. https://doi.org/10.1016/j.ntt.2004.11.003 Grewen, K., Burchinal, M., Vachet, C., Gouttard, S., Gilmore, J. H., Lin, W., … Gerig, G. (2014). Prenatal cocaine effects on brain structure in early infancy. NeuroImage, 101, 114-23. Haroun HSW. (2017). Teratogenicity and teratogenic factors. MOJ Anat Physiol. 7;3(1), 35.39. 10.15406/mojap.2017.03.00082 Hernandez Sampieri, R. C. (2010). Metodología de la investigación. En R. F. Hernandez Sampieri, & P. Baptista Lucio, Metodología de la investigación. Mexico: McGraw-Hill Kalueff, A.V., Tuohimaa, P. (2005). The grooming analysis algorithm discriminates between different levels of anxiety in rats: potential utility for neurobehavioural stress research. Journal of Neuroscience Methods, 143, 169-77. https://doi.org/10.1016/j.jneumeth. 2004.10.001 Katzung, B. G. (2012). Basic and clinical pharmacology. McGraw-Hill. Klintsova, A. Y., Hamilton, D. A., Mooney, S. M., & Petrenko, C. L. M. (2019). Proceedings of the 2018 annual meeting of the fetal alcohol spectrum disorders study group. Alcohol, 81, 47-55. Lezak, K. R., Missig, G., & Carlezon, W. A., Jr (2017). Behavioral methods to study anxiety in rodents. Dialogues in Clinical Neuroscience, 19(2), 181–191. 10.31887/DCNS.2017.19.2/ wcarlezon Magalhães, A., Summavielle, T., Melo, P., Tavares, M. A., & de Sousa, L. (2005). Prenatal cocaine exposure: effects on locomotor activity in rat offspring. Environmental Toxicology and Pharmacology, 19(3), 767-773. https://doi.org/10.1016/j.etap.2004.12.043 Magri, R., Míguez, H., Parodi, V., Hutson, J., Suárez, H., Menéndez, A. (2007). Consumo de alcohol y otras drogas en embarazadas. Archivos de Pediatría de Uruguay, 78(2), 122- 132. Mayes, L. C., & Truman, S. D. (2002). Substance abuse and parenting. Handbook of Parenting. Social Conditions and Applied Parenting. Edited by Marc H. Bornstein Lawrence Erlbaum Associates, Publishers. London. 329-359 Min, M. O., Minnes, S., Yoon, S., & Singer, L. T. (2017). Impact of prenatal cocaine exposure on adolescent behavior. In The Neuroscience of Cocaine (pp. 417-426). Academic Press. Minnes, S., Singer, L. T., Min, M. O., Lang, A. M., Ben-Harush, A., Short, E., & Wu, M. (2014). Comparison of 12-year-old children with prenatal exposure to cocaine and non-exposed controls on caregiver ratings of executive function. Journal of Youth and Adolescence, 43(1), 53-69. Minnes, S., Singer, L., Meeyoung, O.M., Miaoping, W., Lang,A. y Yoon, S. (2014). Effects of prenatal cocaine/polydrug exposure on substance use by age 15. Drug and Alcohol Dependence, 134, 201-210. 10.1016/j.drugalcdep.2013.09.031 Moore, K., &. Persaud, T., & Torchia, M. (2013). Embriología Clínica (8.ª Ed.). España: Elservier Saunder. Moore, K. L., Persaud, T. V. N., & Torchia, M. G. (2018). The Developing Human-E-Book: Clinically Oriented Embryology. Elsevier Health Sciences. Nephew, B. y Febo, M. (2012). Effects of cocaine on maternal behavior and neurochemistry. Current Neuropharmacology, 10, 53-63. https:/doi.org/10.1159/000207491 Niebyl, J. R., Weber, R. J., & Briggs, G. G. (2018). Drugs and Environmental Agents in Pregnancy and Lactation: Teratology and Epidemiology. Gabbe’s Obstetrics Essentials: Normal & Problem Pregnancies E-Book, 38. Nordeng, H. (2016). Drug utilization in pregnant women. Drug Utilization Research: Methods and Applications, 240-247 https://doi.org/10.1002/9781118949740.ch23 Overstreet, D. H., Moy, S. S., Lubin, D. A., Gause, L. R., Lieberman, J. A., & Johns, J. M. (2000). Enduring effects of prenatal cocaine administration on emotional behavior in rats. Physiology & Behavior, 70(1-2), 149-156. https://doi.org/10.1016/S0031-9384(00)00245-6 Papaseit, E., García-Algar, O., & Farré, M. (2013). Talidomida: una historia inacabada. An Pediatr (Barc), 78(5), 283-287. http://dx.doi.org/10.1016/j.anpedi.2012.11.022 Parra-Gámez, L., Reyes Téllez-Girón, J., & Escobar-Briones, C. (2003). La desnutrición y sus consecuencias en el metabolismo intermedio. Rev. Facultad de Medicina UNAM, 46, 32-36. Prasado, M. y Jones, H. (2019). Consumo de drogas durante el embarazo en: Resnik, R., Lockwood, C. J., Moore, T., Greene, M. F., Copel, J., & Silver, R. M. (Eds.). (2019). Creasy & Resnik. Medicina maternofetal: Principios y práctica. Elsevier Health Sciences. Richardson GA, De Genna NM, Goldschmidt L, Larkby C, Donovan JE. (2018). Prenatal cocaine exposure: Direct and indirect associations with 21-year-old offspring substance use and behavior problems. Drug Alcohol Depend. 195, 121-131. 10.1016/j.drugalcdep. 2018.10.033 Riley, E. P., & Vorhees, C. V. (Eds.). (2012). Handbook of Behavioral Teratology. Springer Science & Business Media. Rodrigo, M. J., León, I., García-Pentón, L., Hernández-Cabrera, J. A., & Quiñones, I. (2019). Neglectful maternal caregiving involves altered brain volume in empathy-related areas. Development and Psychopathology, 1-10. 10.1017/S0954579419001469 Salas-Ramirez KY, Frankfurt M, Alexander A, Luine VN, Friedman E. (2010). Prenatal cocaine exposure increases anxiety, impairs cognitive function, and increases dendritic spine density in adult rats: influence of sex. Neuroscience, 169 (3), 1287-1295. 10.1016/j. neuroscience.2010.04.067 Santacruz, MP. (2000). Efectos de la administración crónica de cocaína (30 mg/kg.) sobre la conducta materna y de la administración prenatal de cocaína y de la conducta materna, sobre la conducta emocional y la ingesta de cocaína (30 mg/Kg) y agua en ratones adultos. Acta Colombiana de Psicología, 4, 7-34 Santacruz- Ortega, MP., Maldonado, A., Rodríguez, M. (2001) Efectos de la administración crónica de cocaína en efectos de la administración crónica de cocaína en dosis de 10 y 20 mg/kg sobre la conducta materna en ratones hembras, y la conducta emocional y de libre escogencia de dos botellas en los hijos tratados prenatalmente [Tesis de pregrado en psicología, Universidad Católica de Colombia]. Santacruz Ortega, M. D. P., Marrero Quevedo, R. J., Bethencourth Pérez, J. M., Castellano Gil, M. Á., & Peñate Castro, W. (2016). Efectos de la exposición prenatal a cocaína en la conducta emocional en ratones. Diversitas: Perspectivas en Psicología, 12(2), 275-293. Santacruz-Ortega, MDP. (2020). Effects of Chronic Cocaine Administration during Pregnancy on Pre and Postpartum Maternal Behavior. EC Psychology and Psychiatry, 9, 1, 01-17. Sithisarn, T., Bada, H. S., Dai, H., Randall, D. C., & Legan, S. J. (2011). Effects of perinatal cocaine exposure on open field behavior and the response to corticotropin releasing hormone (CRH) in rat offspring. Brain Research, 1370, 136-144. https://doi.org/10.1016/j. brainres.2010.11.024 Sobrian, S. K., Marr, L., & Ressman, K. (2003). Prenatal cocaine and/or nicotine exposure produces depression and anxiety in aging rats. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 27(3), 501-518. https://doi.org/10.1016/S0278-5846(03)00042-3 Ujházy, E., Mach, M., Navarová, J., Brucknerová, I., & Dubovický, M. (2012). Teratology - past, present and future.Interdisciplinary Toxicology, 5(4), 163-n/a. Walf, A.A., & Frye, C.A. (2007). The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nature Protocols, 2, 322-328. https://doi.org/10.1038/nprot.2007.44 Werboff, J. & Gottlieb, J. S. (1963). Drugs in pregnancy: Behavioral teratology. Obstetrical and Gynecological Survey, 18, 420-423. Wendell, A.D. (2013). Overview and epidemiology of substance abuse in pregnancy. Clinical Obstetrics and Gynecology, 56(1), 91-96. 10.1097/GRF.0b013e31827feeb9. PMID: 23314721. Wickham, M. E., Senthilselvan, A., Wild, T. C., Hoglund, W. L., & Colman, I. (2015). Maternal depressive symptoms during childhood and risky adolescent health behaviors. Pediatrics, 135, 59-67. 10.1542/peds.2014-0628 Worley, F. (2014). Identification and management of prescription drug abuse in pregnancy. The Journal of perinatal & neonatal nursing, 28(3), 196-203. 10.1097/JPN.0000000000000039 Yanai, J., Vigoda, M. J., & Ornoy, A. (2019). Reversal of neurobehavioral teratogenicity in animal models and human: Three decades of progress. Brain Research Bulletin, 150, 328-342. https://doi.org/10.1016/j.brainresbull.2019.06.009 |
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Derechos Reservados - Universidad Católica de Colombia, 2022 |
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Santacruz-Ortega, María del Pilar9bb13de8-ee55-4ffe-84de-ab0be874f031-12023-01-25T22:02:35Z2023-01-25T22:02:35Z2022-12Desde el impresionante precedente de la tragedia de la Talidomida, un ansiolítico, hipnótico y antiemético usado en el primer trimestre de la gestación que causó graves malformaciones cardíacas, renales, digestivas, oftálmicas auditivas y ausencia total o parcial de los miembros superiores/inferiores, entre otras, y a partir de trabajos como (DeSesso, 2019; Moore & Persaud, 2013; Papaseit et al., 2013), y la publicación del minucioso trabajo de Werboff & Gottlieb (1963) se estableció que las drogas de consumo materno durante la gestación –tanto las prescritas como las que no– tienen unos potentes efectos teratogénicos, es decir, producen malformaciones congénitas durante el desarrollo del infante. Estas malformaciones pueden darse en diferentes órganos o tejidos; y cuando ocurren en el sistema nervioso no son tan evidentes, y se reflejan en alteraciones del comportamiento que se pueden manifestar en la infancia, la adolescencia o más tardíamente. Cuando las malformaciones congénitas se observan en el comportamiento, pertenecen al campo de la Teratología Conductual o Teratología Neuroconductual (Minnes et al., 2014; Werboff & Gottlieb, 1963).Primera edicion48 páginasapplication/pdfSantacruz-Ortega, M. P. (2022). Teratología conductual: un apasionante campo de trabajo transdisciplinar. En Alejo-Castañeda, I. E., & Cobo-Charry, M. F. (Eds.) (2022). Investigación en psicología: aplicaciones e intervenciones II (pp. 193-214). Editorial Universidad Católica de Colombia. https://doi.org/10.14718/9786287554320.2022.9978-628-7554-32-0978-628-7554-31-3https://hdl.handle.net/10983/30017https://doi.org/10.14718/9786287554320.2022.9spaEditorial Universidad Católica de ColombiaBogotá240193Alejo-Castañeda, I. E., & Cobo-Charry, M. F. (Eds.) (2022). Investigación en psicología: aplicaciones e intervenciones II. Editorial Universidad Católica de Colombia. https://doi.org/10.14718/9786287554320.2022Investigación en psicología: aplicaciones e intervenciones IIColección Logos Vestigium; no. 17Abel, E. (2012). Behavioral teratogenesis and behavioral mutagenesis: A primer in abnormal development. Springer Science & Business Media.Alwan S, Chambers CD. (2015). Identifying Human Teratogens: An Update. J Pediatr Genet. 4(2), 39-41. https:/doi.org/10.1055/s-0035-1556745Alwan, S., & Bérard, A. (2019). Epidemiology of the Use of Psychotropic Drugs in Pregnant and Nursing Women. In Perinatal Psychopharmacology (pp. 3-16). 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J., & Ornoy, A. (2019). Reversal of neurobehavioral teratogenicity in animal models and human: Three decades of progress. Brain Research Bulletin, 150, 328-342. https://doi.org/10.1016/j.brainresbull.2019.06.009Derechos Reservados - Universidad Católica de Colombia, 2022info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Atribución-CompartirIgual 4.0 Internacional (CC BY-SA 4.0)https://creativecommons.org/licenses/by-sa/4.0/Link publicacionesFETO-MALFORMACIONESSISTEMA NERVIOSO-MALFORMACIONES150 - PsicologíaTeratología conductual: un apasionante campo de trabajo transdisciplinarCapítulo - Parte de Librohttp://purl.org/coar/resource_type/c_3248http://purl.org/coar/version/c_970fb48d4fbd8a85Textinfo:eu-repo/semantics/bookParthttp://purl.org/redcol/resource_type/CAP_LIBinfo:eu-repo/semantics/publishedVersionPublicationORIGINALCapítulo 9. 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