Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.

La corteza prefrontal (CPF) participa en las funciones cognitivas y la regulación del estrés. Las concentraciones de noradrenalina (NA) y serotonina (5-HT) en algunas regiones en el sistema nervioso central son modificadas por el estrés agudo. El efecto depende del estresor y del tiempo que transcur...

Full description

Autores:: García-Saldívar, Norma Laura
Reyes-González López, María
Monroy, Juana
Domínguez, Roberto
Cruz-Morales, Sara Eugenia

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2014

Institución:: Universidad Católica de Colombia

Repositorio:: RIUCaC - Repositorio U. Católica

Idioma:: eng

id	UCATOLICA2_5411490647d45afb0db516d501332a20
oai_identifier_str	oai:repository.ucatolica.edu.co:10983/27981
network_acronym_str	UCATOLICA2
network_name_str	RIUCaC - Repositorio U. Católica
repository_id_str
dc.title.spa.fl_str_mv	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
dc.title.translated.eng.fl_str_mv	Acute effects of restraint, shock and training in the elevated T-Maze on noradrenaline and serotonin systems of the prefrontal cortex.
title	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
spellingShingle	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal. Stressors Noradrenaline Serotonin Prefrontal cortex Corticosterona Estresores Noradrenalina Serotonina Corteza prefrontal Corticosterona
title_short	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
title_full	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
title_fullStr	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
title_full_unstemmed	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
title_sort	Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.
dc.creator.fl_str_mv	García-Saldívar, Norma Laura Reyes-González López, María Monroy, Juana Domínguez, Roberto Cruz-Morales, Sara Eugenia
dc.contributor.author.spa.fl_str_mv	García-Saldívar, Norma Laura Reyes-González López, María Monroy, Juana Domínguez, Roberto Cruz-Morales, Sara Eugenia
dc.subject.eng.fl_str_mv	Stressors Noradrenaline Serotonin Prefrontal cortex Corticosterona
topic	Stressors Noradrenaline Serotonin Prefrontal cortex Corticosterona Estresores Noradrenalina Serotonina Corteza prefrontal Corticosterona
dc.subject.spa.fl_str_mv	Estresores Noradrenalina Serotonina Corteza prefrontal Corticosterona
description	La corteza prefrontal (CPF) participa en las funciones cognitivas y la regulación del estrés. Las concentraciones de noradrenalina (NA) y serotonina (5-HT) en algunas regiones en el sistema nervioso central son modificadas por el estrés agudo. El efecto depende del estresor y del tiempo que transcurra entre el estresor y la evaluación. El objetivo del presente estudio fue evaluar el efecto agudo de diferentes estresores en la actividad de la NA y 5-HT en la CPF y su relación con los niveles de corticosterona. Grupos independientes de ratas (250-270 g) fueron sometidos a restricción, choque o entrenamiento en el laberinto elevado en T (ELET). Los animales fueron sacrificados inmediatamente (T0) o una hora (T1) después de la exposición al estrés. Un grupo no tratado, sacrificado al mismo tiempo que los animales tratados, se incluyó como control. Las muestras de la CPF fueron disecadas y la concentración de NA, 5-HT y sus metabolitos fue detectada por la técnica de HPLC. Las concentraciones de corticosterona fueron medidas en el suero. Ninguno de los tratamientos modificó las concentraciones de NA en la CPF. Al T0 los animales expuestos a choque o al ELET mostraron concentraciones de 5-HT significativamente mayores que el control. Los tratamientos de restricción y choque estuvieron asociados con altas concentraciones de corticosterona al T0 y a T1 después del tratamiento respectivo. En conjunto, los resultados mostraron que en la CPF los sistemas noradrenérgico y serotonérgico y la concentración de corticosterona responden en forma diferente a los distintos estresores.
publishDate	2014
dc.date.accessioned.none.fl_str_mv	2014-07-01 00:00:00 2023-01-23T15:35:56Z
dc.date.available.none.fl_str_mv	2014-07-01 00:00:00 2023-01-23T15:35:56Z
dc.date.issued.none.fl_str_mv	2014-07-01
dc.type.spa.fl_str_mv	Artículo de revista
dc.type.coar.eng.fl_str_mv	http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coarversion.eng.fl_str_mv	http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.content.eng.fl_str_mv	Text
dc.type.driver.eng.fl_str_mv	info:eu-repo/semantics/article
dc.type.local.eng.fl_str_mv	Journal article
dc.type.redcol.eng.fl_str_mv	http://purl.org/redcol/resource_type/ART
dc.type.version.eng.fl_str_mv	info:eu-repo/semantics/publishedVersion
format	http://purl.org/coar/resource_type/c_2df8fbb1
status_str	publishedVersion
dc.identifier.doi.none.fl_str_mv	10.14718/ACP.2014.17.2.3
dc.identifier.eissn.none.fl_str_mv	1909-9711
dc.identifier.issn.none.fl_str_mv	0123-9155
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/10983/27981
dc.identifier.url.none.fl_str_mv	https://doi.org/10.14718/ACP.2014.17.2.3
identifier_str_mv	10.14718/ACP.2014.17.2.3 1909-9711 0123-9155
url	https://hdl.handle.net/10983/27981 https://doi.org/10.14718/ACP.2014.17.2.3
dc.language.iso.eng.fl_str_mv	eng
language	eng
dc.relation.bitstream.none.fl_str_mv	https://actacolombianapsicologia.ucatolica.edu.co/article/download/161/201
dc.relation.citationedition.spa.fl_str_mv	Núm. 2 , Año 2014
dc.relation.citationendpage.none.fl_str_mv	31
dc.relation.citationissue.spa.fl_str_mv	2
dc.relation.citationstartpage.none.fl_str_mv	23
dc.relation.citationvolume.spa.fl_str_mv	17
dc.relation.ispartofjournal.spa.fl_str_mv	Acta Colombiana de Psicología
dc.relation.references.eng.fl_str_mv	Adell, A., Casanovas, J. M. & Artigas, F. (1997). Comparative study in the rat of the actions of different types of stress on the release of 5-HT in raphe nuclei and forebrain areas. Neuropharmacology, 36 (4-5), 735-741. Adell, A., Trullas, R. & Gelpi, E. (1988). Time course of changes in serotonin and noradrenaline in rat brain after predictable or unpredictable shock. Brain Research, 459, 54-59. Amaral, V. C., Santos-Gomes, K. & Nunes-de-Souza, R. L. (2010). Increased corticosterone levels in mice subjected to the rat exposure test. Hormones & Behavior, 57 (2), 128-133. Armario, A., Montero, J. L. & Balasch, J. (1986). Sensitivity of corticosterone and some metabolic variables to graded levels of low intensity stresses in adult male rats. Physiology & Behavior, 37 (4), 559-561. Atkinson, H. C, Waddell, B. J. (1997). Circadian variation in basal plasma corticosterone and adrenocorticotropin in the rat: sexual dimorphism and changes across the estrous cycle. Endocrinology, 138 (9), 3842-3848. Bammer, G. (1982). Pharmacological investigations of neurotransmitter involvement in passive avoidance responding: A review and some new results. Neuroscience & Biobehavioral Reviews, 6 (3), 247-296. Blanco, E., Castilla-Ortega, E., Miranda, R., Begega, A., Aguirre, J. A., Arias, J.L. & Santín, L. J. (2009). Effects of medial prefrontal cortex lesions on anxiety-like behaviour in restrained and non-restrained rats. Behavioral Brain Research, 201 (2), 338-342. Chaouloff, F. (2000). Serotonin, stress and corticoids. Journal of Psychopharmacology, 14, 139-151. Cruz Becerra, D. (2003). Efecto de la privación social en la agresión y la ansiedad de ratas machos Wistar. Acta Colombiana de Psicología, 9, 39-49. Cruz-Morales, S. E., García-Saldívar, N. L., González-López, M. R., Castillo-Roberto, G., Monroy, J. & Domínguez, R. (2008). Acute restriction impairs memory in the elevated T-maze (ETM) and modifies serotonergic activity in the dorsolateral striatum. Behavioral Brain Research, 19 (1), 187-191. Cruz-Morales, S. E., Durán-Arévalo, M. Díaz del Guante, M. A., Quirarte, G. L. & Prado-Alcalá, R. A. (1992). A threshold for the protective effect of over-reinforced passive avoidance against scopolaminutesutese-induced amnesia. Behavioral and Neural Biology, 57 (3), 256-259. De la Garza, R. & Mahoney, J. J. (2004). A distinct neurochemical profile in WKY rats at baseline and response, o acute stress: implications for animal models of anxiety and depression. Brain Research, 1021 (2), 209-218. Domínguez, R. & Cruz-Morales, S. E. (2011). The ovarian innervation participates in the regulation of ovarian functions. Endocrinology & Metabolic Syndrome. Retrieved April 28, 2014 from http://dx.doi.org/10.4172/2161-1017.S4-001 Domínguez, R., Cruz-Morales, S. E., Carvalho, M. C., Xavier, M. & Brandão, M. L. (2003a). Effect of steroid injection to newborn rats on serotonin activity in frontal cortex and raphe. Neuroreport, 14 (4), 597-599. Domínguez, R., Cruz-Morales, S. E., Carvalho, M. C., Xavier, M. & Brandão M. L. (2003b). Sex differences in serotonergic activity in dorsal and median raphe nucleus. Physiology & Behavior, 80 (2-3), 203-210. Dunn, A. J. & Swiergiel, A. H. (2008). The role of corticotropinreleasing factor and noradrenaline in stress-related responses, and the inter-relationships between the two systems. European Journal of Pharmacology, 583 (2-3), 186-193. Fan Y, Chen P, Li Y, Cui K, Noel DM, Cumminutesutess ED, Peterson DJ, Brown RW, Zhu MY. (2014). Corticosterone adminutesutesistration up-regulated expression of norepinephrine transporter and dopaminutesutese β-hydroxylase in rat locus coeruleus and its terminutesutesal regions. Journal of Neurochemistry, 128 (3), 445-458. Finlay, J. M., Zigmond, M. J. & Abercrombie, E. D. (1995). Increased dopaminutesutese and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam. Neuroscience, 64 (3), 619-628. Fujino K, Yoshitake T, Inoue O, Ibii N, Kehr J, Ishida J, Nohta H. & Yamaguchi M. (2002). Increased serotonin release in mice frontal cortex and hippocampus induced by acute physiological stressors. Neuroscience Letters, 320, 91-95. Graeff, F. G., Viana, M. B. & Tomaz, C. (1993). The elevated T-maze, a new experimental model of anxiety and memory: effect of diazepam. Brazilian Journal of Medical and Biological Research, 26 (1), 67-70. Hendley, E. D., Burrows, G. H., Robinson, E. S., Heidenreich, K. A. & Bulman, C. A. (1977). Acute stress and the brain norepinephrine uptake mechanism in the rat. Pharmacology Biochemistry and Behavior, 6 (2), 197-202. Holmes, A. & Wellman, C. L. (2009). Stress induced prefrontal reorganization and executive dysfunction in rodents, Neuroscience and Biobehavioral Reviews, 33 (6), 773-783. Iimori, K., Tanaka, M., Kohno, Y., Ida, Y., Nakagawa, R., Hoaki, Y., et. al, (1982). Psychological stress enhances noradrenaline turnover in specific brain regions in rats. Pharmacology Biochemistry and Behavior, 16 (4), 637-640. Inoue, T., Tsuchiya, K. & Koyama, T. (1994). Regional changes in dopaminutesutese and serotonin activation with various intensity of physical and psychological stress in the rat brain. Pharmacology, Biochemistry and Behavior, 49 (4), 911-920. Kant, G. J., Mougey, E. H., Pennington, L. L. & Meyerhoff, J. L. (1983). Graded shock stress elevates pituitary cyclic AMP and plasma beta-endorphin, beta-LPH corticosterone and prolactin. Life Sciences, 33 (26), 2657-2663. Kerdelhué, B., Bojda, F., Lesieur, P., Pasqualini, C., el Abed, A., enoir, V., et al, (1989). Median eminutesutesence dopaminutesutese and serotonin neuronal activity. Temporal relationship to preovulatory prolactin and luteinizing hormone surges. Neuroendocrinology, 49 (2), 176-180. Kirby, L. G., Chou-Green, J. M., Davis, K. & Lucki, I. (1997). The effects of different stressors on extracellular 5-hydroxytryptaminutesutese and 5-hydroxyindolacetic acid. Brain Research, 760 (1-2), 218-220. Kuhar, M.J., Minutesutesneman, K. & Muly, E.C. Catecholaminutesuteses. (2006). In G. J. Siegel, R. W. Albers, S.T., Brady and D.L. Price (Eds.). Basic Neurochemistry: Molecular, Cellular, and Medical Aspects 7th Edition, (pp. 211-225). Burlington, MA, Elsevier Academic Press. Kvetnansky, R., Sabban, E. L. & Palkovits, M. (2009). Catecholaminutesutesergic systems in stress: structural and molecular genetic approaches. Physiological Reviews, 89 (2), 535-606. Lucas, L. R., Wang, Ch., McCall, T. & McEwen, B. S. (2007). Effects of immobilization stress on neurochemical marks in the motivational system of the male rat. Brain Research, 1155, 108-115. Mannari, C., Origlia, N., Scatena, A., Del Debbio, A., Catena, M., Dell’agnello, G., Barraco, A., Giovannini, L., Dell’osso, L., Domenici, L., Piccinni, A. (2008). BDNF level in the rat prefrontal cortex increases following chronic but not acute treatment with duloxetine, a dual acting inhibitor of noradrenaline and serotonin re-uptake. Cellular and Molecular Neurobiology, 28 (3), 457-468. Mokler, D. J., Torres, O. I., Galler, J. R. & Morgane, P. J. (2007). Stress-induced changes in extracellular dopaminutesutese and serotonin in the medial prefrontal cortex and dorsal hippocampus of prenatally malnourished rats. Brain Research, 1148, 226-233. Myhrer, T. (2003). Neurotransmitter systems involved in learning and memory in the rat: a meta-analysis based on studies of four behavioral tasks. Brain Research Reviews, 41 (2-3), 268-287. Natelson, B. H., Tapp, W. N., Adamus, J. E., Mittler, J. C. & Levin, B. E. (1981). Humoral indices of stress in rats. Physiology & Behavior, 26 (6), 1049-1054. Pacak, K. & McCarty, R. (2000). Acute stress response: experimental. In G Fink (Ed.) Encyclopedia of stress (pp 8-17), San Diego: Academic Press. Pacák, K., Palkovits, M., Kvetnanský, R., Yadid, G., Kopin, I. J. & Goldstein, D. S. (1995). Effects of various stressors on in vivo norepinephrine release in the hypothalamic paraventricular nucleus and on the pituitary-adrenocortical axis. Annual New York Academic Science, 771, 115-130. Pacák, K., Palkovits, M., Yadid, G., Kvetnansky, R., Kopin, I. J. & Goldstein, D. S. (1998). Heterogeneous neurochemical responses to different stressors: a test of Selye’s doctrine of nonspecificity. American Journal Physiology, 275 (4 Pt2), R1247-R1255. Pacák, K. & Palkovits, M. (2001). Stressor specificity of central neuroendocrine responses: Implications for stress-related disorders. Endocrine Reviews, 22 (4), 502-548. Paxinos, G, & Watson, C. (1997). The rat brain in stereotaxic coordinates (San Diego, CA/Academic Press). Rabasa, C., Muñoz-Abellán, C., Daviu, N., Nadal, R. & Armario, A. (2011). Repeated exposure to immobilization or two different shock intensities reveals differential adaptation of the hypothalamic–pituitary–adrenal axis. Physiology & Behavior, 103 (2), 125-133. Radley, J. J., Williams, B. & Sawchenko, P. E. (2008). Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamus-pituitary-adrenal responses to acute emotional stress. Journal of Neuroscience, 28 (22), 5806-5816. Robbins, T. W. & Roberts, A. C. (2007). Differential regulation of fronto-executive function by the monoaminutesuteses and acetylcholine. Cerebral Cortex, Suppl 1, 1151-1160. Sandi, C & Pinelo-Nava, M. T. (2007). Stress and memory: behavioral effects and neurobiological mechanisms, Neural Plasticity, 2007 Doi: 10.1155/2007/78970, 1-20. Shanks, N., Griffithst, J. & Anisman, H. (1994). Norepinephrine and serotonin alterations following chronic stressor exposure: mouse strain differences. Pharmacology Biochemistry and Behavior, 49 (1), 57-65. Shin, L. M. & Liberzon, I. (2010). The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology, 35 (1), 169-191. Shinba, T., Ozawa, N., Yoshii, M. & Yamamoto, K. (2010). Delayed increase of brain noradrenaline after acute shock stress in rats. Neurochemical Research, 35 (3), 412-417. Smith, D. G., Davis, R. J., Gehlert, D. R. & Nomikos, G. G. (2006.). Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoaminutesuteses in mice: Comparison with immobilization stress and reversal by chlordiazepoxide. Brain Research, 1114, 24-30. Sudha, S. & Pradhan, N. (1995). Stress-Induced changes in regional monoaminutesutese metabolism and behavior in rats. Physiology & Behavior, 57 (6), 1061-1066. Swiergiel, A. H., Leskov, I. L. & Dunn, A. J. (2008) Effects of chronic and acute stressors and CRF on depression-like behavior in mice. Behavioral Brain Research, 186 (1), 32-40. Szafarczyk, A., Ixart, G., Gaillet, S., Siaud, P., Barbanel, G., Malaval, F. & Assenmacher, I. (1993). Stress. Neurophysiologic studies. Encephale, 19 (1), 137-142. Viana, M. B., Tomas, C. & Graeff, F. G. (1994). The elevated T-maze: a new animal model of anxiety and memory. Pharmacology Biochemistry and Behavior, 49 (3), 549-554.
dc.rights.eng.fl_str_mv	Norma Laura García Saldíva - 2014
dc.rights.accessrights.eng.fl_str_mv	info:eu-repo/semantics/openAccess
dc.rights.coar.eng.fl_str_mv	http://purl.org/coar/access_right/c_abf2
dc.rights.uri.eng.fl_str_mv	https://creativecommons.org/licenses/by-nc-sa/4.0/
rights_invalid_str_mv	Norma Laura García Saldíva - 2014 http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv	openAccess
dc.format.mimetype.eng.fl_str_mv	application/pdf
dc.publisher.spa.fl_str_mv	Universidad Católica de Colombia
dc.source.eng.fl_str_mv	https://actacolombianapsicologia.ucatolica.edu.co/article/view/161
institution	Universidad Católica de Colombia
bitstream.url.fl_str_mv	https://repository.ucatolica.edu.co/bitstreams/fde08a63-1dd6-4851-b2ce-30eadd228dd3/download
bitstream.checksum.fl_str_mv	32182cdcf7be82652b0220a90234dbe6
bitstream.checksumAlgorithm.fl_str_mv	MD5
repository.name.fl_str_mv	Repositorio Institucional Universidad Católica de Colombia - RIUCaC
repository.mail.fl_str_mv	bdigital@metabiblioteca.com
_version_	1812183339474354176
spelling	García-Saldívar, Norma Laura495f84e5-6f0d-4acf-85b9-cb58d56d1144Reyes-González López, María367faa01-51c9-445d-9e38-662de67da367Monroy, Juana6335e29d-2eba-4852-aae2-9fdd4421ce1a300Domínguez, Roberto82fcbad8-2017-44fd-ac23-fb0c2feabefb300Cruz-Morales, Sara Eugeniac910031b-2d12-414e-8282-ac1322ffd16e2014-07-01 00:00:002023-01-23T15:35:56Z2014-07-01 00:00:002023-01-23T15:35:56Z2014-07-01La corteza prefrontal (CPF) participa en las funciones cognitivas y la regulación del estrés. Las concentraciones de noradrenalina (NA) y serotonina (5-HT) en algunas regiones en el sistema nervioso central son modificadas por el estrés agudo. El efecto depende del estresor y del tiempo que transcurra entre el estresor y la evaluación. El objetivo del presente estudio fue evaluar el efecto agudo de diferentes estresores en la actividad de la NA y 5-HT en la CPF y su relación con los niveles de corticosterona. Grupos independientes de ratas (250-270 g) fueron sometidos a restricción, choque o entrenamiento en el laberinto elevado en T (ELET). Los animales fueron sacrificados inmediatamente (T0) o una hora (T1) después de la exposición al estrés. Un grupo no tratado, sacrificado al mismo tiempo que los animales tratados, se incluyó como control. Las muestras de la CPF fueron disecadas y la concentración de NA, 5-HT y sus metabolitos fue detectada por la técnica de HPLC. Las concentraciones de corticosterona fueron medidas en el suero. Ninguno de los tratamientos modificó las concentraciones de NA en la CPF. Al T0 los animales expuestos a choque o al ELET mostraron concentraciones de 5-HT significativamente mayores que el control. Los tratamientos de restricción y choque estuvieron asociados con altas concentraciones de corticosterona al T0 y a T1 después del tratamiento respectivo. En conjunto, los resultados mostraron que en la CPF los sistemas noradrenérgico y serotonérgico y la concentración de corticosterona responden en forma diferente a los distintos estresores.The prefrontal cortex (PFC) participates in cognitive functions and stress regulation. Noradrenaline (NA) and serotonin (5-HT) levels in some regions of the central nervous system are modified by acute stress. The effects depend on the type of stressor and the time elapsed between the presence of the stressor and the assessment. The aims of the present study were to assess the acute effect of different stressors on NA and 5-HT activities in the PFC and its relation with corticosterone levels. Independent groups of male Wistar rats (250-280 g) were submitted to restraint, footshock or training in the elevated T-maze (ETMT). The animals were sacrificed immediately (T0) or one hour (T1) after stress exposure. An untreated group sacrificed concurrently with treated animals was included as control. Samples of the PFC were dissected and the concentration of NA, 5-HT and their metabolites were measured by HPLC. Corticosterone levels were measured in serum. None of the treatments modified NA levels in the PFC. Animals exposed to footshock or ETMT showed significantly higher concentrations of 5-HT at T0. Restraint and footshock treatments were associated with higher corticosterone levels at T0 and T1 after the respective treatment. Taken together the results show that in the PFC, the noradrenergic and serotonergic systems, and the corticosterone levels respond in different ways to different stressors.application/pdf10.14718/ACP.2014.17.2.31909-97110123-9155https://hdl.handle.net/10983/27981https://doi.org/10.14718/ACP.2014.17.2.3engUniversidad Católica de Colombiahttps://actacolombianapsicologia.ucatolica.edu.co/article/download/161/201Núm. 2 , Año 20143122317Acta Colombiana de PsicologíaAdell, A., Casanovas, J. M. & Artigas, F. (1997). Comparative study in the rat of the actions of different types of stress on the release of 5-HT in raphe nuclei and forebrain areas. Neuropharmacology, 36 (4-5), 735-741.Adell, A., Trullas, R. & Gelpi, E. (1988). Time course of changes in serotonin and noradrenaline in rat brain after predictable or unpredictable shock. Brain Research, 459, 54-59.Amaral, V. C., Santos-Gomes, K. & Nunes-de-Souza, R. L. (2010). Increased corticosterone levels in mice subjected to the rat exposure test. Hormones & Behavior, 57 (2), 128-133.Armario, A., Montero, J. L. & Balasch, J. (1986). Sensitivity of corticosterone and some metabolic variables to graded levels of low intensity stresses in adult male rats. Physiology & Behavior, 37 (4), 559-561.Atkinson, H. C, Waddell, B. J. (1997). Circadian variation in basal plasma corticosterone and adrenocorticotropin in the rat: sexual dimorphism and changes across the estrous cycle. Endocrinology, 138 (9), 3842-3848.Bammer, G. (1982). Pharmacological investigations of neurotransmitter involvement in passive avoidance responding: A review and some new results. Neuroscience & Biobehavioral Reviews, 6 (3), 247-296.Blanco, E., Castilla-Ortega, E., Miranda, R., Begega, A., Aguirre, J. A., Arias, J.L. & Santín, L. J. (2009). Effects of medial prefrontal cortex lesions on anxiety-like behaviour in restrained and non-restrained rats. Behavioral Brain Research, 201 (2), 338-342.Chaouloff, F. (2000). Serotonin, stress and corticoids. Journal of Psychopharmacology, 14, 139-151.Cruz Becerra, D. (2003). Efecto de la privación social en la agresión y la ansiedad de ratas machos Wistar. Acta Colombiana de Psicología, 9, 39-49.Cruz-Morales, S. E., García-Saldívar, N. L., González-López, M. R., Castillo-Roberto, G., Monroy, J. & Domínguez, R. (2008). Acute restriction impairs memory in the elevated T-maze (ETM) and modifies serotonergic activity in the dorsolateral striatum. Behavioral Brain Research, 19 (1), 187-191.Cruz-Morales, S. E., Durán-Arévalo, M. Díaz del Guante, M. A., Quirarte, G. L. & Prado-Alcalá, R. A. (1992). A threshold for the protective effect of over-reinforced passive avoidance against scopolaminutesutese-induced amnesia. Behavioral and Neural Biology, 57 (3), 256-259.De la Garza, R. & Mahoney, J. J. (2004). A distinct neurochemical profile in WKY rats at baseline and response, o acute stress: implications for animal models of anxiety and depression. Brain Research, 1021 (2), 209-218.Domínguez, R. & Cruz-Morales, S. E. (2011). The ovarian innervation participates in the regulation of ovarian functions. Endocrinology & Metabolic Syndrome. Retrieved April 28, 2014 from http://dx.doi.org/10.4172/2161-1017.S4-001Domínguez, R., Cruz-Morales, S. E., Carvalho, M. C., Xavier, M. & Brandão, M. L. (2003a). Effect of steroid injection to newborn rats on serotonin activity in frontal cortex and raphe. Neuroreport, 14 (4), 597-599.Domínguez, R., Cruz-Morales, S. E., Carvalho, M. C., Xavier, M. & Brandão M. L. (2003b). Sex differences in serotonergic activity in dorsal and median raphe nucleus. Physiology & Behavior, 80 (2-3), 203-210.Dunn, A. J. & Swiergiel, A. H. (2008). The role of corticotropinreleasing factor and noradrenaline in stress-related responses, and the inter-relationships between the two systems. European Journal of Pharmacology, 583 (2-3), 186-193.Fan Y, Chen P, Li Y, Cui K, Noel DM, Cumminutesutess ED, Peterson DJ, Brown RW, Zhu MY. (2014). Corticosterone adminutesutesistration up-regulated expression of norepinephrine transporter and dopaminutesutese β-hydroxylase in rat locus coeruleus and its terminutesutesal regions. Journal of Neurochemistry, 128 (3), 445-458.Finlay, J. M., Zigmond, M. J. & Abercrombie, E. D. (1995). Increased dopaminutesutese and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: effects of diazepam. Neuroscience, 64 (3), 619-628.Fujino K, Yoshitake T, Inoue O, Ibii N, Kehr J, Ishida J, Nohta H. & Yamaguchi M. (2002). Increased serotonin release in mice frontal cortex and hippocampus induced by acute physiological stressors. Neuroscience Letters, 320, 91-95.Graeff, F. G., Viana, M. B. & Tomaz, C. (1993). The elevated T-maze, a new experimental model of anxiety and memory: effect of diazepam. Brazilian Journal of Medical and Biological Research, 26 (1), 67-70.Hendley, E. D., Burrows, G. H., Robinson, E. S., Heidenreich, K. A. & Bulman, C. A. (1977). Acute stress and the brain norepinephrine uptake mechanism in the rat. Pharmacology Biochemistry and Behavior, 6 (2), 197-202.Holmes, A. & Wellman, C. L. (2009). Stress induced prefrontal reorganization and executive dysfunction in rodents, Neuroscience and Biobehavioral Reviews, 33 (6), 773-783.Iimori, K., Tanaka, M., Kohno, Y., Ida, Y., Nakagawa, R., Hoaki, Y., et. al, (1982). Psychological stress enhances noradrenaline turnover in specific brain regions in rats. Pharmacology Biochemistry and Behavior, 16 (4), 637-640.Inoue, T., Tsuchiya, K. & Koyama, T. (1994). Regional changes in dopaminutesutese and serotonin activation with various intensity of physical and psychological stress in the rat brain. Pharmacology, Biochemistry and Behavior, 49 (4), 911-920.Kant, G. J., Mougey, E. H., Pennington, L. L. & Meyerhoff, J. L. (1983). Graded shock stress elevates pituitary cyclic AMP and plasma beta-endorphin, beta-LPH corticosterone and prolactin. Life Sciences, 33 (26), 2657-2663.Kerdelhué, B., Bojda, F., Lesieur, P., Pasqualini, C., el Abed, A., enoir, V., et al, (1989). Median eminutesutesence dopaminutesutese and serotonin neuronal activity. Temporal relationship to preovulatory prolactin and luteinizing hormone surges. Neuroendocrinology, 49 (2), 176-180.Kirby, L. G., Chou-Green, J. M., Davis, K. & Lucki, I. (1997). The effects of different stressors on extracellular 5-hydroxytryptaminutesutese and 5-hydroxyindolacetic acid. Brain Research, 760 (1-2), 218-220.Kuhar, M.J., Minutesutesneman, K. & Muly, E.C. Catecholaminutesuteses. (2006). In G. J. Siegel, R. W. Albers, S.T., Brady and D.L. Price (Eds.). Basic Neurochemistry: Molecular, Cellular, and Medical Aspects 7th Edition, (pp. 211-225). Burlington, MA, Elsevier Academic Press.Kvetnansky, R., Sabban, E. L. & Palkovits, M. (2009). Catecholaminutesutesergic systems in stress: structural and molecular genetic approaches. Physiological Reviews, 89 (2), 535-606.Lucas, L. R., Wang, Ch., McCall, T. & McEwen, B. S. (2007). Effects of immobilization stress on neurochemical marks in the motivational system of the male rat. Brain Research, 1155, 108-115.Mannari, C., Origlia, N., Scatena, A., Del Debbio, A., Catena, M., Dell’agnello, G., Barraco, A., Giovannini, L., Dell’osso, L., Domenici, L., Piccinni, A. (2008). BDNF level in the rat prefrontal cortex increases following chronic but not acute treatment with duloxetine, a dual acting inhibitor of noradrenaline and serotonin re-uptake. Cellular and Molecular Neurobiology, 28 (3), 457-468.Mokler, D. J., Torres, O. I., Galler, J. R. & Morgane, P. J. (2007). Stress-induced changes in extracellular dopaminutesutese and serotonin in the medial prefrontal cortex and dorsal hippocampus of prenatally malnourished rats. Brain Research, 1148, 226-233.Myhrer, T. (2003). Neurotransmitter systems involved in learning and memory in the rat: a meta-analysis based on studies of four behavioral tasks. Brain Research Reviews, 41 (2-3), 268-287.Natelson, B. H., Tapp, W. N., Adamus, J. E., Mittler, J. C. & Levin, B. E. (1981). Humoral indices of stress in rats. Physiology & Behavior, 26 (6), 1049-1054.Pacak, K. & McCarty, R. (2000). Acute stress response: experimental. In G Fink (Ed.) Encyclopedia of stress (pp 8-17), San Diego: Academic Press.Pacák, K., Palkovits, M., Kvetnanský, R., Yadid, G., Kopin, I. J. & Goldstein, D. S. (1995). Effects of various stressors on in vivo norepinephrine release in the hypothalamic paraventricular nucleus and on the pituitary-adrenocortical axis. Annual New York Academic Science, 771, 115-130.Pacák, K., Palkovits, M., Yadid, G., Kvetnansky, R., Kopin, I. J. & Goldstein, D. S. (1998). Heterogeneous neurochemical responses to different stressors: a test of Selye’s doctrine of nonspecificity. American Journal Physiology, 275 (4 Pt2), R1247-R1255.Pacák, K. & Palkovits, M. (2001). Stressor specificity of central neuroendocrine responses: Implications for stress-related disorders. Endocrine Reviews, 22 (4), 502-548.Paxinos, G, & Watson, C. (1997). The rat brain in stereotaxic coordinates (San Diego, CA/Academic Press).Rabasa, C., Muñoz-Abellán, C., Daviu, N., Nadal, R. & Armario, A. (2011). Repeated exposure to immobilization or two different shock intensities reveals differential adaptation of the hypothalamic–pituitary–adrenal axis. Physiology & Behavior, 103 (2), 125-133.Radley, J. J., Williams, B. & Sawchenko, P. E. (2008). Noradrenergic innervation of the dorsal medial prefrontal cortex modulates hypothalamus-pituitary-adrenal responses to acute emotional stress. Journal of Neuroscience, 28 (22), 5806-5816.Robbins, T. W. & Roberts, A. C. (2007). Differential regulation of fronto-executive function by the monoaminutesuteses and acetylcholine. Cerebral Cortex, Suppl 1, 1151-1160.Sandi, C & Pinelo-Nava, M. T. (2007). Stress and memory: behavioral effects and neurobiological mechanisms, Neural Plasticity, 2007 Doi: 10.1155/2007/78970, 1-20.Shanks, N., Griffithst, J. & Anisman, H. (1994). Norepinephrine and serotonin alterations following chronic stressor exposure: mouse strain differences. Pharmacology Biochemistry and Behavior, 49 (1), 57-65.Shin, L. M. & Liberzon, I. (2010). The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology, 35 (1), 169-191.Shinba, T., Ozawa, N., Yoshii, M. & Yamamoto, K. (2010). Delayed increase of brain noradrenaline after acute shock stress in rats. Neurochemical Research, 35 (3), 412-417.Smith, D. G., Davis, R. J., Gehlert, D. R. & Nomikos, G. G. (2006.). Exposure to predator odor stress increases efflux of frontal cortex acetylcholine and monoaminutesuteses in mice: Comparison with immobilization stress and reversal by chlordiazepoxide. Brain Research, 1114, 24-30.Sudha, S. & Pradhan, N. (1995). Stress-Induced changes in regional monoaminutesutese metabolism and behavior in rats. Physiology & Behavior, 57 (6), 1061-1066.Swiergiel, A. H., Leskov, I. L. & Dunn, A. J. (2008) Effects of chronic and acute stressors and CRF on depression-like behavior in mice. Behavioral Brain Research, 186 (1), 32-40.Szafarczyk, A., Ixart, G., Gaillet, S., Siaud, P., Barbanel, G., Malaval, F. & Assenmacher, I. (1993). Stress. Neurophysiologic studies. Encephale, 19 (1), 137-142.Viana, M. B., Tomas, C. & Graeff, F. G. (1994). The elevated T-maze: a new animal model of anxiety and memory. Pharmacology Biochemistry and Behavior, 49 (3), 549-554.Norma Laura García Saldíva - 2014info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/https://actacolombianapsicologia.ucatolica.edu.co/article/view/161StressorsNoradrenalineSerotoninPrefrontal cortexCorticosteronaEstresoresNoradrenalinaSerotoninaCorteza prefrontalCorticosteronaEfectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.Acute effects of restraint, shock and training in the elevated T-Maze on noradrenaline and serotonin systems of the prefrontal cortex.Artículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Textinfo:eu-repo/semantics/articleJournal articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionPublicationOREORE.xmltext/xml2915https://repository.ucatolica.edu.co/bitstreams/fde08a63-1dd6-4851-b2ce-30eadd228dd3/download32182cdcf7be82652b0220a90234dbe6MD5110983/27981oai:repository.ucatolica.edu.co:10983/279812023-03-24 15:58:39.956https://creativecommons.org/licenses/by-nc-sa/4.0/Norma Laura García Saldíva - 2014https://repository.ucatolica.edu.coRepositorio Institucional Universidad Católica de Colombia - RIUCaCbdigital@metabiblioteca.com

Efectos agudos de la restricción, choque y entrenamiento en el laberinto elevado en T en los sistemas de noradrenalina y serotonina en la corteza prefrontal.

Publicaciones similares