Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023

Introducción: a pesar de los múltiples tratamientos para la vaginosis bacteriana, más de la mitad de las mujeres experimentan recurrencia de los síntomas. Objetivo: evaluar la efectividad y seguridad de las intervenciones terapéuticas en el manejo de la vaginosis bacteriana recurrente, en mujeres no...

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Autores:: Espitia de la Hoz, Franklin

Tipo de recurso:: Article of journal

Fecha de publicación:: 2024

Institución:: Universidad de Cartagena

Repositorio:: Repositorio Universidad de Cartagena

Idioma:: spa

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network_acronym_str	UCART2
network_name_str	Repositorio Universidad de Cartagena
repository_id_str
dc.title.spa.fl_str_mv	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
dc.title.translated.eng.fl_str_mv	Treatment of recurrent Bacterial Vaginosis, update 2023
title	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
spellingShingle	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023 Vaginosis Bacterial Therapeutics Leukorrhea Anti-Bacterial Agents Gardnerella vaginalis Vaginosis Bacteriana Terapéutica Leucorrea Antibacterianos Gardnerella vaginalis
title_short	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
title_full	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
title_fullStr	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
title_full_unstemmed	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
title_sort	Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
dc.creator.fl_str_mv	Espitia de la Hoz, Franklin
dc.contributor.author.spa.fl_str_mv	Espitia de la Hoz, Franklin
dc.subject.eng.fl_str_mv	Vaginosis Bacterial Therapeutics Leukorrhea Anti-Bacterial Agents Gardnerella vaginalis
topic	Vaginosis Bacterial Therapeutics Leukorrhea Anti-Bacterial Agents Gardnerella vaginalis Vaginosis Bacteriana Terapéutica Leucorrea Antibacterianos Gardnerella vaginalis
dc.subject.spa.fl_str_mv	Vaginosis Bacteriana Terapéutica Leucorrea Antibacterianos Gardnerella vaginalis
description	Introducción: a pesar de los múltiples tratamientos para la vaginosis bacteriana, más de la mitad de las mujeres experimentan recurrencia de los síntomas. Objetivo: evaluar la efectividad y seguridad de las intervenciones terapéuticas en el manejo de la vaginosis bacteriana recurrente, en mujeres no gestantes. Métodos: se realizó una búsqueda sistemática de la literatura en diferentes bases de datos electrónicas (MEDLINE, Scopus, Embase, Biblioteca Cochrane, entre otras); entre 1990 y 2023. Se utilizaron términos de búsqueda libres y estandarizados. Los desenlaces evaluados fueron el tiempo de retardo en la aparición de VB mayor a 12 meses y las reacciones adversas. Resultados: se tuvieron en cuenta 84 publicaciones. El metronidazol y la clindamicina siguen siendo el régimen terapéutico recomendado en el tratamiento de la vaginosis bacteriana aguda, y en la recurrente; el secnidazol y nifuratel han mostrado su positivo efecto, escalonando una posición entre estos regímenes (los cuales no solo podrían aumentar las tasas de curación clínica y microbiológica, sino disminución en la recurrencia). La proporción de reacciones adversas fueron más notables con los nitroimidazoles y la clindamicina, sin hallarse reportes del nifuratel. Conclusión: la revisión mostró que en el tratamiento de la vaginosis bacteriana recurrente no se observan diferencias significativas entre los regímenes tradicionales, lo mismo sucede con la seguridad, ya que las reacciones adversas son escasas y no suelen ser graves. Se necesitan ensayos clínicos que ayuden a aumentar las opciones de tratamiento para la VB recurrente, dándole paso al nifuratel y a otras opciones terapéuticas.
publishDate	2024
dc.date.accessioned.none.fl_str_mv	2024-11-12T15:28:35Z 2024-11-13T09:00:19Z
dc.date.available.none.fl_str_mv	2024-11-12T15:28:35Z 2024-11-13T09:00:19Z
dc.date.issued.none.fl_str_mv	2024-11-12
dc.type.spa.fl_str_mv	Artículo de revista
dc.type.coar.fl_str_mv	http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/publishedVersion
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dc.type.coar.spa.fl_str_mv	http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_dcae04bc
dc.type.content.spa.fl_str_mv	Text
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/article
dc.type.local.eng.fl_str_mv	Journal article
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dc.identifier.issn.none.fl_str_mv	2215-7840
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/11227/18461
dc.identifier.doi.none.fl_str_mv	10.32997/rcb-2024-4239
dc.identifier.eissn.none.fl_str_mv	2389-7252
dc.identifier.url.none.fl_str_mv	https://doi.org/10.32997/rcb-2024-4239
identifier_str_mv	2215-7840 10.32997/rcb-2024-4239 2389-7252
url	https://hdl.handle.net/11227/18461 https://doi.org/10.32997/rcb-2024-4239
dc.language.iso.spa.fl_str_mv	spa
language	spa
dc.relation.ispartofjournal.spa.fl_str_mv	Revista Ciencias Biomédicas
dc.relation.bitstream.none.fl_str_mv	https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/download/4239/3821
dc.relation.citationendpage.none.fl_str_mv	79
dc.relation.citationissue.spa.fl_str_mv	2
dc.relation.citationstartpage.none.fl_str_mv	56
dc.relation.citationvolume.spa.fl_str_mv	13
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dc.rights.spa.fl_str_mv	Franklin Espitia de la Hoz - 2024
dc.rights.uri.spa.fl_str_mv	https://creativecommons.org/licenses/by-nc-nd/4.0
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spelling	Espitia de la Hoz, Franklin2024-11-12T15:28:35Z2024-11-13T09:00:19Z2024-11-12T15:28:35Z2024-11-13T09:00:19Z2024-11-122215-7840https://hdl.handle.net/11227/1846110.32997/rcb-2024-42392389-7252https://doi.org/10.32997/rcb-2024-4239Introducción: a pesar de los múltiples tratamientos para la vaginosis bacteriana, más de la mitad de las mujeres experimentan recurrencia de los síntomas. Objetivo: evaluar la efectividad y seguridad de las intervenciones terapéuticas en el manejo de la vaginosis bacteriana recurrente, en mujeres no gestantes. Métodos: se realizó una búsqueda sistemática de la literatura en diferentes bases de datos electrónicas (MEDLINE, Scopus, Embase, Biblioteca Cochrane, entre otras); entre 1990 y 2023. Se utilizaron términos de búsqueda libres y estandarizados. Los desenlaces evaluados fueron el tiempo de retardo en la aparición de VB mayor a 12 meses y las reacciones adversas. Resultados: se tuvieron en cuenta 84 publicaciones. El metronidazol y la clindamicina siguen siendo el régimen terapéutico recomendado en el tratamiento de la vaginosis bacteriana aguda, y en la recurrente; el secnidazol y nifuratel han mostrado su positivo efecto, escalonando una posición entre estos regímenes (los cuales no solo podrían aumentar las tasas de curación clínica y microbiológica, sino disminución en la recurrencia). La proporción de reacciones adversas fueron más notables con los nitroimidazoles y la clindamicina, sin hallarse reportes del nifuratel. Conclusión: la revisión mostró que en el tratamiento de la vaginosis bacteriana recurrente no se observan diferencias significativas entre los regímenes tradicionales, lo mismo sucede con la seguridad, ya que las reacciones adversas son escasas y no suelen ser graves. Se necesitan ensayos clínicos que ayuden a aumentar las opciones de tratamiento para la VB recurrente, dándole paso al nifuratel y a otras opciones terapéuticas.Introduction: despite multiple treatments for bacterial vaginosis (BV), more than half of women experience recurrence of symptoms. Objective: to evaluate the effectiveness and safety of therapeutic interventions in the management of recurrent bacterial vaginosis in non-pregnant women. Methods: a systematic literature search was carried out in different electronic databases (MEDLINE, Scopus, Embase, Cochrane Library, among others); between 1990 and 2022. Free and standardized search terms were used. The outcomes evaluated were the delay time in the appearance of BV greater than 12 months and the adverse reactions. Results: eighty-four publications were included. Metronidazole and clindamycin continue to be the recommended therapeutic regimen in the treatment of acute bacterial vaginosis, and in recurrent one; secnidazole and nifuratel have shown their positive effect, staggering one position between these regimens (which could not only increase clinical and microbiological cure rates, but also decrease recurrence). The proportion of adverse reactions were more notable with nitroimidazoles and clindamycin, without finding reports of nifuratel. Conclusions: the review showed that in the treatment of recurrent bacterial vaginosis there are no significant differences between traditional regimens, the same happens with safety, since adverse reactions are rare and not usually serious. Clinical trials are needed to help increase treatment options for recurrent BV, making way for nifuratel and other treatment options.application/pdfspaUniversidad de CartagenaRevista Ciencias Biomédicashttps://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/download/4239/38217925613Sobel JD. Bacterial vaginosis. Annu Rev Med. 2000;51:349-56. doi: 10.1146/annurev.med.51.1.349.Espitia De La Hoz FJ. Evaluación de la eficacia y seguridad del policresuleno en el tratamiento de la vaginitis mixta, Armenia, Colombia, 2017-2019. Estudio aleatorizado. Arch Med (Manizales). 2021;21(1):45-56. doi: 10.30554/archmed.21.1.3756.2020.Jung HS, Ehlers MM, Lombaard H, Redelinghuys MJ, Kock MM. Etiology of bacterial vaginosis and polymicrobial biofilm formation. Crit Rev Microbiol. 2017;43(6):651-67. doi: 10.1080/1040841X.2017.1291579.Fredricks DN, Fiedler TL, Marrazzo JM. Molecular identification of bacteria associated with bacterial vaginosis. 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Efficacy and safety of Nifuratel-Nystatin in the treatment of mixed vaginitis, in pregnant women from Quindío, 2013-2017. Randomized clinical trial. Pregn Womens Health Care Int J. 2022;1(2):1-7. doi: 10.53902/PWHCIJ.2021.01.000508.Hillier SL. Treatment of bacterial vaginosis. Female Patient. 1995;5:6-16.Chapple A, Hassell K, Nicolson M, Cantrill J. 'You don't really feel you can function normally': women's perceptions and personal management of vaginal thrush. J Reprod Infant Psychol. 2000;18(4):309-19. doi: 10.1080/713683045.Johnson SR, Griffiths H, Humberstone FJ. Attitudes and experience of women to common vaginal infections. J Low Genit Tract Dis. 2010;14(4):287-94. doi: 10.1097/LGT.0b013e3181d85bb7.Franklin Espitia de la Hoz - 2024https://creativecommons.org/licenses/by-nc-nd/4.0http://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessEsta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.https://revistas.unicartagena.edu.co/index.php/cbiomedicas/article/view/4239VaginosisBacterialTherapeuticsLeukorrheaAnti-Bacterial AgentsGardnerella vaginalisVaginosis BacterianaTerapéuticaLeucorreaAntibacterianosGardnerella vaginalisTratamiento de la Vaginosis Bacteriana recurrente, actualización 2023Treatment of recurrent Bacterial Vaginosis, update 2023Artículo de revistainfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articleJournal articlehttp://purl.org/redcol/resource_type/ARTREVPublicationOREORE.xmltext/xml2523https://repositorio.unicartagena.edu.co/bitstreams/433c8bdd-3e49-4506-9305-165b3e6a1963/download88a880052e1d163fea43a58fa2e8e6bfMD5111227/18461oai:repositorio.unicartagena.edu.co:11227/184612024-11-13 04:00:19.949https://creativecommons.org/licenses/by-nc-nd/4.0Franklin Espitia de la Hoz - 2024metadata.onlyhttps://repositorio.unicartagena.edu.coBiblioteca Digital Universidad de Cartagenabdigital@metabiblioteca.com

Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023

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