Genitourinary symptoms and sexual function in women with primary ovarian insufficiency

Objective: There are limited studies on urogenital symptoms in women who experience menopause before the age of 40years due to primary ovarian insufficiency (POI) or bilateral oophorectomy (surgical POI). This study aimed to compare the urogenital symptoms, including sexuality, of women with POI to those without the condition. Methods: This cross-sectional study conducted was in seven Latin American countries, in which postmenopausal women (with POI and non-POI) were surveyed with a general questionnaire, the Menopause Rating Scale (MRS) and the six-item Female Sexual Function Index (FSFI-6). The association of premature menopause with more urogenital symptoms and lower sexual function was evaluated with logistic regression analysis. Results: Women with POI experience more urogenital symptoms (MRS urogenital score: 3.54±3.16 vs. 3.15±2.89, p<0.05) and have lower sexual function (total FSFI-6 score: 13.71±7.55 vs. 14.77±7.57 p<0.05) than women who experience menopause at a normal age range. There were no significant differences in symptoms when comparing women based on the type of POI (idiopathic or surgical). After adjusting for covariates, our logistic regression model determined that POI is associated with more urogenital symptoms (odds ratio [OR]: 1.38, 95% confidence interval [CI] 1.06–1.80) and lower sexual function (OR: 1.67, 95% CI 1.25–2.25). Conclusion: POI, whether idiopathic or secondary to bilateral oophorectomy, is associated with symptoms that affect vaginal and sexual health

• Autores: Blümel, J. E.; Chedraui, P.; Vallejo, M. S.; Dextre, M.; Elizalde, A.; Escalante, C.; Monterrosa-Castro, A.; Ñañez, M.; Ojeda, E.; Rey, C.; Rodríguez, D.; Rodrigues, M. A.; Salinas, C.; Tserotas, K.
• Tipo de recurso: Article of journal
• Fecha de publicación: 2024
• Institución: Universidad de Cartagena
• Repositorio: Repositorio Universidad de Cartagena
• Idioma: eng
• OAI Identifier: oai:repositorio.unicartagena.edu.co:11227/19474
• Acceso en línea: https://hdl.handle.net/11227/19474
• Palabra clave: 3. Ciencias Médicas y de la Salud; Primary ovarian insufficiency; Premature menopause; Surgical menopause; Sexuality; Genitourinary symptom; Insuficiencia ovárica primaria; Menopausia prematura; Menopausia quirúrgica; Sexualidad; Síntomas genitourinarios; ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
• Rights: openAccess
• License: https://creativecommons.org/licenses/by-nc/4.0/