Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa

At present, conventional endodontics is a procedure that presents a variety of side effects in the future, that is why pulp regeneration and/or revascularization therapies are developed, which are usually performed in immature permanent teeth in order to generate more conservative treatments. In rec...

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Autores:: Arias González, Yenifer Caterine

Tipo de recurso:: Trabajo de grado de pregrado

Fecha de publicación:: 2021

Institución:: Universidad Antonio Nariño

Repositorio:: Repositorio UAN

Idioma:: spa

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dc.title.es_ES.fl_str_mv	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
spellingShingle	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa Revascularización Revitalización pulpar Celulas madre Células madre de la pulpa dental Regeneración pulpar Dientes maduros Dientes adultos Regeneración endodóntica Ingeniería de tejidos 600 Revascularization Pulp revitalization Stem cell Dental pulp stem cell Pulp regeneration Mature teeth Adult teeth Endodontic regeneration Tissue engineering
title_short	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_full	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_fullStr	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_full_unstemmed	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_sort	Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
dc.creator.fl_str_mv	Arias González, Yenifer Caterine
dc.contributor.advisor.spa.fl_str_mv	Martínez Betancourt, Juan José
dc.contributor.author.spa.fl_str_mv	Arias González, Yenifer Caterine
dc.subject.es_ES.fl_str_mv	Revascularización Revitalización pulpar Celulas madre Células madre de la pulpa dental Regeneración pulpar Dientes maduros Dientes adultos Regeneración endodóntica Ingeniería de tejidos
topic	Revascularización Revitalización pulpar Celulas madre Células madre de la pulpa dental Regeneración pulpar Dientes maduros Dientes adultos Regeneración endodóntica Ingeniería de tejidos 600 Revascularization Pulp revitalization Stem cell Dental pulp stem cell Pulp regeneration Mature teeth Adult teeth Endodontic regeneration Tissue engineering
dc.subject.ddc.es_ES.fl_str_mv	600
dc.subject.keyword.es_ES.fl_str_mv	Revascularization Pulp revitalization Stem cell Dental pulp stem cell Pulp regeneration Mature teeth Adult teeth Endodontic regeneration Tissue engineering
description	At present, conventional endodontics is a procedure that presents a variety of side effects in the future, that is why pulp regeneration and/or revascularization therapies are developed, which are usually performed in immature permanent teeth in order to generate more conservative treatments. In recent years and in the recent advances in tissue engineering, a way has been registered for pulp therapy that allows us the complete pulp regeneration of mature teeth, in which advantage is taken of the differentiation capacity of residual pulp stem cells. These cells are capable of generating a highly vascularized living tissue rich in connective tissue, which colonizes the available pulp space. However, until the completion of this review, no method has been reported in the literature as viable for clinical application in humans.
publishDate	2021
dc.date.issued.spa.fl_str_mv	2021-11-27
dc.date.accessioned.none.fl_str_mv	2022-04-29T03:14:27Z
dc.date.available.none.fl_str_mv	2022-04-29T03:14:27Z
dc.type.spa.fl_str_mv	Trabajo de grado (Pregrado y/o Especialización)
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dc.identifier.uri.none.fl_str_mv	http://repositorio.uan.edu.co/handle/123456789/6358
dc.identifier.bibliographicCitation.spa.fl_str_mv	Abbass, M. M. S., El-Rashidy, A. A., Sadek, K. M., Moshy, S. El, Radwan, I. A., Rady, D., Dörfer, C. E., & Fawzy El-Sayed, K. M. (2020). Hydrogels and dentin– pulp complex regeneration: From the benchtop to clinical translation. Polymers, 12(12), 1–65. https://doi.org/10.3390/polym12122935 Bertassoni, L. E. (2020). Progress and Challenges in Microengineering the Dental Pulp Vascular Microenvironment. Journal of Endodontics, 46(9), S90– S100. https://doi.org/10.1016/j.joen.2020.06.033 Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R., & Khoury, M. (2020). CellBased Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial. Journal of Dental Research, 99(5), 523–529. https://doi.org/10.1177/0022034520913242 Chrepa, V., Henry, M. A., Daniel, B. J., & Diogenes, A. (2015). Delivery of apical mesenchymal stem cells into root canals of mature teeth. Journal of Dental Research, 94(12), 1653–1659. https://doi.org/10.1177/0022034515596527 de Cara, S. P. H. M., Origassa, C. S. T., de Sá Silva, F., Moreira, M. S. N. A., de Almeida, D. C., Pedroni, A. C. F., Carvalho, G. L., Cury, D. P., Câmara, N. O. S., & Marques, M. M. (2019). Angiogenic properties of dental pulp stem cells conditioned medium on endothelial cells in vitro and in rodent orthotopic dental pulp regeneration. Heliyon, 5(4). https://doi.org/10.1016/j.heliyon.2019.e01560 Diana, R., Ardhani, R., Kristanti, Y., & Santosa, P. (2020). Dental pulp stem cells response on the nanotopography of scaffold to regenerate dentin-pulp complex tissue. Regenerative Therapy, 15, 243–250. https://doi.org/10.1016/j.reth.2020.09.007 Diogenes, A. (2020). Trigeminal Sensory Neurons and Pulp Regeneration. Journal of Endodontics, 46(9), S71–S80. https://doi.org/10.1016/j.joen.2020.06.038 Diogenes, A., & Hargreaves, K. M. (2017). Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics. Journal of Endodontics, 43(9), S95–S101. https://doi.org/10.1016/j.joen.2017.07.012 Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry - Part I: Stem cell sources. Journal of Prosthodontic Research, 56(3), 151–165. https://doi.org/10.1016/j.jpor.2012.06.001 Fawzy El-Sayed, K. M., Ahmed, G. M., Abouauf, E. A., & Schwendicke, F. (2019). Stem/progenitor cell-mediated pulpal tissue regeneration: a systematic review and meta-analysis. International Endodontic Journal, 52(11), 1573– 1585. https://doi.org/10.1111/iej.13177
dc.identifier.instname.spa.fl_str_mv	instname:Universidad Antonio Nariño
dc.identifier.reponame.spa.fl_str_mv	reponame:Repositorio Institucional UAN
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url	http://repositorio.uan.edu.co/handle/123456789/6358
identifier_str_mv	Abbass, M. M. S., El-Rashidy, A. A., Sadek, K. M., Moshy, S. El, Radwan, I. A., Rady, D., Dörfer, C. E., & Fawzy El-Sayed, K. M. (2020). Hydrogels and dentin– pulp complex regeneration: From the benchtop to clinical translation. Polymers, 12(12), 1–65. https://doi.org/10.3390/polym12122935 Bertassoni, L. E. (2020). Progress and Challenges in Microengineering the Dental Pulp Vascular Microenvironment. Journal of Endodontics, 46(9), S90– S100. https://doi.org/10.1016/j.joen.2020.06.033 Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R., & Khoury, M. (2020). CellBased Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial. Journal of Dental Research, 99(5), 523–529. https://doi.org/10.1177/0022034520913242 Chrepa, V., Henry, M. A., Daniel, B. J., & Diogenes, A. (2015). Delivery of apical mesenchymal stem cells into root canals of mature teeth. Journal of Dental Research, 94(12), 1653–1659. https://doi.org/10.1177/0022034515596527 de Cara, S. P. H. M., Origassa, C. S. T., de Sá Silva, F., Moreira, M. S. N. A., de Almeida, D. C., Pedroni, A. C. F., Carvalho, G. L., Cury, D. P., Câmara, N. O. S., & Marques, M. M. (2019). Angiogenic properties of dental pulp stem cells conditioned medium on endothelial cells in vitro and in rodent orthotopic dental pulp regeneration. Heliyon, 5(4). https://doi.org/10.1016/j.heliyon.2019.e01560 Diana, R., Ardhani, R., Kristanti, Y., & Santosa, P. (2020). Dental pulp stem cells response on the nanotopography of scaffold to regenerate dentin-pulp complex tissue. Regenerative Therapy, 15, 243–250. https://doi.org/10.1016/j.reth.2020.09.007 Diogenes, A. (2020). Trigeminal Sensory Neurons and Pulp Regeneration. Journal of Endodontics, 46(9), S71–S80. https://doi.org/10.1016/j.joen.2020.06.038 Diogenes, A., & Hargreaves, K. M. (2017). Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics. Journal of Endodontics, 43(9), S95–S101. https://doi.org/10.1016/j.joen.2017.07.012 Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry - Part I: Stem cell sources. Journal of Prosthodontic Research, 56(3), 151–165. https://doi.org/10.1016/j.jpor.2012.06.001 Fawzy El-Sayed, K. M., Ahmed, G. M., Abouauf, E. A., & Schwendicke, F. (2019). Stem/progenitor cell-mediated pulpal tissue regeneration: a systematic review and meta-analysis. International Endodontic Journal, 52(11), 1573– 1585. https://doi.org/10.1111/iej.13177 instname:Universidad Antonio Nariño reponame:Repositorio Institucional UAN repourl:https://repositorio.uan.edu.co/
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language	spa
dc.rights.none.fl_str_mv	Acceso abierto
dc.rights.license.spa.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
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eu_rights_str_mv	openAccess
dc.publisher.spa.fl_str_mv	Universidad Antonio Nariño
dc.publisher.program.spa.fl_str_mv	Odontología
dc.publisher.faculty.spa.fl_str_mv	Facultad de Odontología
dc.publisher.campus.spa.fl_str_mv	Armenia
institution	Universidad Antonio Nariño
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spelling	Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)Acceso abiertohttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Martínez Betancourt, Juan JoséArias González, Yenifer Caterine20571712536205717161632022-04-29T03:14:27Z2022-04-29T03:14:27Z2021-11-27http://repositorio.uan.edu.co/handle/123456789/6358Abbass, M. M. S., El-Rashidy, A. A., Sadek, K. M., Moshy, S. El, Radwan, I. A., Rady, D., Dörfer, C. E., & Fawzy El-Sayed, K. M. (2020). Hydrogels and dentin– pulp complex regeneration: From the benchtop to clinical translation. Polymers, 12(12), 1–65. https://doi.org/10.3390/polym12122935Bertassoni, L. E. (2020). Progress and Challenges in Microengineering the Dental Pulp Vascular Microenvironment. Journal of Endodontics, 46(9), S90– S100. https://doi.org/10.1016/j.joen.2020.06.033Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R., & Khoury, M. (2020). CellBased Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial. Journal of Dental Research, 99(5), 523–529. https://doi.org/10.1177/0022034520913242Chrepa, V., Henry, M. A., Daniel, B. J., & Diogenes, A. (2015). Delivery of apical mesenchymal stem cells into root canals of mature teeth. Journal of Dental Research, 94(12), 1653–1659. https://doi.org/10.1177/0022034515596527de Cara, S. P. H. M., Origassa, C. S. T., de Sá Silva, F., Moreira, M. S. N. A., de Almeida, D. C., Pedroni, A. C. F., Carvalho, G. L., Cury, D. P., Câmara, N. O. S., & Marques, M. M. (2019). Angiogenic properties of dental pulp stem cells conditioned medium on endothelial cells in vitro and in rodent orthotopic dental pulp regeneration. Heliyon, 5(4). https://doi.org/10.1016/j.heliyon.2019.e01560Diana, R., Ardhani, R., Kristanti, Y., & Santosa, P. (2020). Dental pulp stem cells response on the nanotopography of scaffold to regenerate dentin-pulp complex tissue. Regenerative Therapy, 15, 243–250. https://doi.org/10.1016/j.reth.2020.09.007Diogenes, A. (2020). Trigeminal Sensory Neurons and Pulp Regeneration. Journal of Endodontics, 46(9), S71–S80. https://doi.org/10.1016/j.joen.2020.06.038Diogenes, A., & Hargreaves, K. M. (2017). Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics. Journal of Endodontics, 43(9), S95–S101. https://doi.org/10.1016/j.joen.2017.07.012Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry - Part I: Stem cell sources. Journal of Prosthodontic Research, 56(3), 151–165. https://doi.org/10.1016/j.jpor.2012.06.001Fawzy El-Sayed, K. M., Ahmed, G. M., Abouauf, E. A., & Schwendicke, F. (2019). Stem/progenitor cell-mediated pulpal tissue regeneration: a systematic review and meta-analysis. International Endodontic Journal, 52(11), 1573– 1585. https://doi.org/10.1111/iej.13177instname:Universidad Antonio Nariñoreponame:Repositorio Institucional UANrepourl:https://repositorio.uan.edu.co/At present, conventional endodontics is a procedure that presents a variety of side effects in the future, that is why pulp regeneration and/or revascularization therapies are developed, which are usually performed in immature permanent teeth in order to generate more conservative treatments. In recent years and in the recent advances in tissue engineering, a way has been registered for pulp therapy that allows us the complete pulp regeneration of mature teeth, in which advantage is taken of the differentiation capacity of residual pulp stem cells. These cells are capable of generating a highly vascularized living tissue rich in connective tissue, which colonizes the available pulp space. However, until the completion of this review, no method has been reported in the literature as viable for clinical application in humans.En la actualidad la endodoncia convencional es un procedimiento que presenta variedad de efectos secundarios a futuro, por eso se desarrollan terapias de regeneración y/o revascularización pulpar, que normalmente se realizan en dientes permanentes inmaduros con el fin de generar tratamientos más conservadores. En los últimos años y en los avances recientes en la ingeniería de tejidos se ha registrado un camino para la terapia pulpar lo cual permite la regeneración pulpar completa de los dientes maduros, en la cual se toma ventaja de la capacidad de diferenciación de las células madre pulpares residuales. Estas células son capaces de generar un tejido vivo altamente vascularizado y rico en tejido conjuntivo, el cual coloniza el espacio pulpar disponible. Sin embargo y hasta la realización de esta revisión de la literatura, ningún método se ha reportado como viable para su aplicación clínica en humanos.Odontólogo(a)PregradoPresencialMonografíaspaUniversidad Antonio NariñoOdontologíaFacultad de OdontologíaArmeniaRevascularizaciónRevitalización pulparCelulas madreCélulas madre de la pulpa dentalRegeneración pulparDientes madurosDientes adultosRegeneración endodónticaIngeniería de tejidos600RevascularizationPulp revitalizationStem cellDental pulp stem cellPulp regenerationMature teethAdult teethEndodontic regenerationTissue engineeringRegeneración pulpar en dientes maduros usando células madre, una revisión narrativaTrabajo de grado (Pregrado y/o Especialización)http://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/version/c_970fb48d4fbd8a85EspecializadaORIGINAL2021_JuanJoseMartinez.pdf2021_JuanJoseMartinez.pdfTrabajo completoapplication/pdf400843https://repositorio.uan.edu.co/bitstreams/7f1020f1-f19a-4f19-a6e4-e7fec7688418/downloadbd8dfbee3a2c5e41eacf345254d2381aMD532021_JuanJoseMartinez_Autorizacion.pdf2021_JuanJoseMartinez_Autorizacion.pdfAutorizacion consultaapplication/pdf514566https://repositorio.uan.edu.co/bitstreams/833f12fc-0757-4310-a3b6-8004e51b61a7/download7df755f9773fc1d217f67b4bb2ec3f3eMD512021_JuanJoseMartinez_Acta.pdf2021_JuanJoseMartinez_Acta.pdfActa sustentaciónimage/jpeg1190920https://repositorio.uan.edu.co/bitstreams/fe4bc492-9a44-4d8d-b047-da01ca32203a/download57a3d5beee9039ad16a1f51424a19112MD52123456789/6358oai:repositorio.uan.edu.co:123456789/63582024-10-09 22:54:07.085https://creativecommons.org/licenses/by-nc-nd/4.0/Acceso abiertoopen.accesshttps://repositorio.uan.edu.coRepositorio Institucional UANalertas.repositorio@uan.edu.co

Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa

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