Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa

At present, conventional endodontics is a procedure that presents a variety of side effects in the future, that is why pulp regeneration and/or revascularization therapies are developed, which are usually performed in immature permanent teeth in order to generate more conservative treatments. In rec...

Full description

Autores:
Arias González, Yenifer Caterine
Tipo de recurso:
Trabajo de grado de pregrado
Fecha de publicación:
2021
Institución:
Universidad Antonio Nariño
Repositorio:
Repositorio UAN
Idioma:
spa
OAI Identifier:
oai:repositorio.uan.edu.co:123456789/6358
Acceso en línea:
http://repositorio.uan.edu.co/handle/123456789/6358
Palabra clave:
Revascularización
Revitalización pulpar
Celulas madre
Células madre de la pulpa dental
Regeneración pulpar
Dientes maduros
Dientes adultos
Regeneración endodóntica
Ingeniería de tejidos
600
Revascularization
Pulp revitalization
Stem cell
Dental pulp stem cell
Pulp regeneration
Mature teeth
Adult teeth
Endodontic regeneration
Tissue engineering
Rights
openAccess
License
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
id UAntonioN2_a2f551d2884f7d47676098c575d58c4c
oai_identifier_str oai:repositorio.uan.edu.co:123456789/6358
network_acronym_str UAntonioN2
network_name_str Repositorio UAN
repository_id_str
dc.title.es_ES.fl_str_mv Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
spellingShingle Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
Revascularización
Revitalización pulpar
Celulas madre
Células madre de la pulpa dental
Regeneración pulpar
Dientes maduros
Dientes adultos
Regeneración endodóntica
Ingeniería de tejidos
600
Revascularization
Pulp revitalization
Stem cell
Dental pulp stem cell
Pulp regeneration
Mature teeth
Adult teeth
Endodontic regeneration
Tissue engineering
title_short Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_full Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_fullStr Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_full_unstemmed Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
title_sort Regeneración pulpar en dientes maduros usando células madre, una revisión narrativa
dc.creator.fl_str_mv Arias González, Yenifer Caterine
dc.contributor.advisor.spa.fl_str_mv Martínez Betancourt, Juan José
dc.contributor.author.spa.fl_str_mv Arias González, Yenifer Caterine
dc.subject.es_ES.fl_str_mv Revascularización
Revitalización pulpar
Celulas madre
Células madre de la pulpa dental
Regeneración pulpar
Dientes maduros
Dientes adultos
Regeneración endodóntica
Ingeniería de tejidos
topic Revascularización
Revitalización pulpar
Celulas madre
Células madre de la pulpa dental
Regeneración pulpar
Dientes maduros
Dientes adultos
Regeneración endodóntica
Ingeniería de tejidos
600
Revascularization
Pulp revitalization
Stem cell
Dental pulp stem cell
Pulp regeneration
Mature teeth
Adult teeth
Endodontic regeneration
Tissue engineering
dc.subject.ddc.es_ES.fl_str_mv 600
dc.subject.keyword.es_ES.fl_str_mv Revascularization
Pulp revitalization
Stem cell
Dental pulp stem cell
Pulp regeneration
Mature teeth
Adult teeth
Endodontic regeneration
Tissue engineering
description At present, conventional endodontics is a procedure that presents a variety of side effects in the future, that is why pulp regeneration and/or revascularization therapies are developed, which are usually performed in immature permanent teeth in order to generate more conservative treatments. In recent years and in the recent advances in tissue engineering, a way has been registered for pulp therapy that allows us the complete pulp regeneration of mature teeth, in which advantage is taken of the differentiation capacity of residual pulp stem cells. These cells are capable of generating a highly vascularized living tissue rich in connective tissue, which colonizes the available pulp space. However, until the completion of this review, no method has been reported in the literature as viable for clinical application in humans.
publishDate 2021
dc.date.issued.spa.fl_str_mv 2021-11-27
dc.date.accessioned.none.fl_str_mv 2022-04-29T03:14:27Z
dc.date.available.none.fl_str_mv 2022-04-29T03:14:27Z
dc.type.spa.fl_str_mv Trabajo de grado (Pregrado y/o Especialización)
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
format http://purl.org/coar/resource_type/c_7a1f
dc.identifier.uri.none.fl_str_mv http://repositorio.uan.edu.co/handle/123456789/6358
dc.identifier.bibliographicCitation.spa.fl_str_mv Abbass, M. M. S., El-Rashidy, A. A., Sadek, K. M., Moshy, S. El, Radwan, I. A., Rady, D., Dörfer, C. E., & Fawzy El-Sayed, K. M. (2020). Hydrogels and dentin– pulp complex regeneration: From the benchtop to clinical translation. Polymers, 12(12), 1–65. https://doi.org/10.3390/polym12122935
Bertassoni, L. E. (2020). Progress and Challenges in Microengineering the Dental Pulp Vascular Microenvironment. Journal of Endodontics, 46(9), S90– S100. https://doi.org/10.1016/j.joen.2020.06.033
Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R., & Khoury, M. (2020). CellBased Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial. Journal of Dental Research, 99(5), 523–529. https://doi.org/10.1177/0022034520913242
Chrepa, V., Henry, M. A., Daniel, B. J., & Diogenes, A. (2015). Delivery of apical mesenchymal stem cells into root canals of mature teeth. Journal of Dental Research, 94(12), 1653–1659. https://doi.org/10.1177/0022034515596527
de Cara, S. P. H. M., Origassa, C. S. T., de Sá Silva, F., Moreira, M. S. N. A., de Almeida, D. C., Pedroni, A. C. F., Carvalho, G. L., Cury, D. P., Câmara, N. O. S., & Marques, M. M. (2019). Angiogenic properties of dental pulp stem cells conditioned medium on endothelial cells in vitro and in rodent orthotopic dental pulp regeneration. Heliyon, 5(4). https://doi.org/10.1016/j.heliyon.2019.e01560
Diana, R., Ardhani, R., Kristanti, Y., & Santosa, P. (2020). Dental pulp stem cells response on the nanotopography of scaffold to regenerate dentin-pulp complex tissue. Regenerative Therapy, 15, 243–250. https://doi.org/10.1016/j.reth.2020.09.007
Diogenes, A. (2020). Trigeminal Sensory Neurons and Pulp Regeneration. Journal of Endodontics, 46(9), S71–S80. https://doi.org/10.1016/j.joen.2020.06.038
Diogenes, A., & Hargreaves, K. M. (2017). Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics. Journal of Endodontics, 43(9), S95–S101. https://doi.org/10.1016/j.joen.2017.07.012
Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry - Part I: Stem cell sources. Journal of Prosthodontic Research, 56(3), 151–165. https://doi.org/10.1016/j.jpor.2012.06.001
Fawzy El-Sayed, K. M., Ahmed, G. M., Abouauf, E. A., & Schwendicke, F. (2019). Stem/progenitor cell-mediated pulpal tissue regeneration: a systematic review and meta-analysis. International Endodontic Journal, 52(11), 1573– 1585. https://doi.org/10.1111/iej.13177
dc.identifier.instname.spa.fl_str_mv instname:Universidad Antonio Nariño
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional UAN
dc.identifier.repourl.spa.fl_str_mv repourl:https://repositorio.uan.edu.co/
url http://repositorio.uan.edu.co/handle/123456789/6358
identifier_str_mv Abbass, M. M. S., El-Rashidy, A. A., Sadek, K. M., Moshy, S. El, Radwan, I. A., Rady, D., Dörfer, C. E., & Fawzy El-Sayed, K. M. (2020). Hydrogels and dentin– pulp complex regeneration: From the benchtop to clinical translation. Polymers, 12(12), 1–65. https://doi.org/10.3390/polym12122935
Bertassoni, L. E. (2020). Progress and Challenges in Microengineering the Dental Pulp Vascular Microenvironment. Journal of Endodontics, 46(9), S90– S100. https://doi.org/10.1016/j.joen.2020.06.033
Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R., & Khoury, M. (2020). CellBased Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial. Journal of Dental Research, 99(5), 523–529. https://doi.org/10.1177/0022034520913242
Chrepa, V., Henry, M. A., Daniel, B. J., & Diogenes, A. (2015). Delivery of apical mesenchymal stem cells into root canals of mature teeth. Journal of Dental Research, 94(12), 1653–1659. https://doi.org/10.1177/0022034515596527
de Cara, S. P. H. M., Origassa, C. S. T., de Sá Silva, F., Moreira, M. S. N. A., de Almeida, D. C., Pedroni, A. C. F., Carvalho, G. L., Cury, D. P., Câmara, N. O. S., & Marques, M. M. (2019). Angiogenic properties of dental pulp stem cells conditioned medium on endothelial cells in vitro and in rodent orthotopic dental pulp regeneration. Heliyon, 5(4). https://doi.org/10.1016/j.heliyon.2019.e01560
Diana, R., Ardhani, R., Kristanti, Y., & Santosa, P. (2020). Dental pulp stem cells response on the nanotopography of scaffold to regenerate dentin-pulp complex tissue. Regenerative Therapy, 15, 243–250. https://doi.org/10.1016/j.reth.2020.09.007
Diogenes, A. (2020). Trigeminal Sensory Neurons and Pulp Regeneration. Journal of Endodontics, 46(9), S71–S80. https://doi.org/10.1016/j.joen.2020.06.038
Diogenes, A., & Hargreaves, K. M. (2017). Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics. Journal of Endodontics, 43(9), S95–S101. https://doi.org/10.1016/j.joen.2017.07.012
Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry - Part I: Stem cell sources. Journal of Prosthodontic Research, 56(3), 151–165. https://doi.org/10.1016/j.jpor.2012.06.001
Fawzy El-Sayed, K. M., Ahmed, G. M., Abouauf, E. A., & Schwendicke, F. (2019). Stem/progenitor cell-mediated pulpal tissue regeneration: a systematic review and meta-analysis. International Endodontic Journal, 52(11), 1573– 1585. https://doi.org/10.1111/iej.13177
instname:Universidad Antonio Nariño
reponame:Repositorio Institucional UAN
repourl:https://repositorio.uan.edu.co/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.rights.none.fl_str_mv Acceso abierto
dc.rights.license.spa.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.rights.uri.spa.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Acceso abierto
https://creativecommons.org/licenses/by-nc-nd/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.publisher.spa.fl_str_mv Universidad Antonio Nariño
dc.publisher.program.spa.fl_str_mv Odontología
dc.publisher.faculty.spa.fl_str_mv Facultad de Odontología
dc.publisher.campus.spa.fl_str_mv Armenia
institution Universidad Antonio Nariño
bitstream.url.fl_str_mv https://repositorio.uan.edu.co/bitstreams/7f1020f1-f19a-4f19-a6e4-e7fec7688418/download
https://repositorio.uan.edu.co/bitstreams/833f12fc-0757-4310-a3b6-8004e51b61a7/download
https://repositorio.uan.edu.co/bitstreams/fe4bc492-9a44-4d8d-b047-da01ca32203a/download
bitstream.checksum.fl_str_mv bd8dfbee3a2c5e41eacf345254d2381a
7df755f9773fc1d217f67b4bb2ec3f3e
57a3d5beee9039ad16a1f51424a19112
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional UAN
repository.mail.fl_str_mv alertas.repositorio@uan.edu.co
_version_ 1812928330487300096
spelling Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)Acceso abiertohttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Martínez Betancourt, Juan JoséArias González, Yenifer Caterine20571712536205717161632022-04-29T03:14:27Z2022-04-29T03:14:27Z2021-11-27http://repositorio.uan.edu.co/handle/123456789/6358Abbass, M. M. S., El-Rashidy, A. A., Sadek, K. M., Moshy, S. El, Radwan, I. A., Rady, D., Dörfer, C. E., & Fawzy El-Sayed, K. M. (2020). Hydrogels and dentin– pulp complex regeneration: From the benchtop to clinical translation. Polymers, 12(12), 1–65. https://doi.org/10.3390/polym12122935Bertassoni, L. E. (2020). Progress and Challenges in Microengineering the Dental Pulp Vascular Microenvironment. Journal of Endodontics, 46(9), S90– S100. https://doi.org/10.1016/j.joen.2020.06.033Brizuela, C., Meza, G., Urrejola, D., Quezada, M. A., Concha, G., Ramírez, V., Angelopoulos, I., Cadiz, M. I., Tapia-Limonchi, R., & Khoury, M. (2020). CellBased Regenerative Endodontics for Treatment of Periapical Lesions: A Randomized, Controlled Phase I/II Clinical Trial. Journal of Dental Research, 99(5), 523–529. https://doi.org/10.1177/0022034520913242Chrepa, V., Henry, M. A., Daniel, B. J., & Diogenes, A. (2015). Delivery of apical mesenchymal stem cells into root canals of mature teeth. Journal of Dental Research, 94(12), 1653–1659. https://doi.org/10.1177/0022034515596527de Cara, S. P. H. M., Origassa, C. S. T., de Sá Silva, F., Moreira, M. S. N. A., de Almeida, D. C., Pedroni, A. C. F., Carvalho, G. L., Cury, D. P., Câmara, N. O. S., & Marques, M. M. (2019). Angiogenic properties of dental pulp stem cells conditioned medium on endothelial cells in vitro and in rodent orthotopic dental pulp regeneration. Heliyon, 5(4). https://doi.org/10.1016/j.heliyon.2019.e01560Diana, R., Ardhani, R., Kristanti, Y., & Santosa, P. (2020). Dental pulp stem cells response on the nanotopography of scaffold to regenerate dentin-pulp complex tissue. Regenerative Therapy, 15, 243–250. https://doi.org/10.1016/j.reth.2020.09.007Diogenes, A. (2020). Trigeminal Sensory Neurons and Pulp Regeneration. Journal of Endodontics, 46(9), S71–S80. https://doi.org/10.1016/j.joen.2020.06.038Diogenes, A., & Hargreaves, K. M. (2017). Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics. Journal of Endodontics, 43(9), S95–S101. https://doi.org/10.1016/j.joen.2017.07.012Egusa, H., Sonoyama, W., Nishimura, M., Atsuta, I., & Akiyama, K. (2012). Stem cells in dentistry - Part I: Stem cell sources. Journal of Prosthodontic Research, 56(3), 151–165. https://doi.org/10.1016/j.jpor.2012.06.001Fawzy El-Sayed, K. M., Ahmed, G. M., Abouauf, E. A., & Schwendicke, F. (2019). Stem/progenitor cell-mediated pulpal tissue regeneration: a systematic review and meta-analysis. International Endodontic Journal, 52(11), 1573– 1585. https://doi.org/10.1111/iej.13177instname:Universidad Antonio Nariñoreponame:Repositorio Institucional UANrepourl:https://repositorio.uan.edu.co/At present, conventional endodontics is a procedure that presents a variety of side effects in the future, that is why pulp regeneration and/or revascularization therapies are developed, which are usually performed in immature permanent teeth in order to generate more conservative treatments. In recent years and in the recent advances in tissue engineering, a way has been registered for pulp therapy that allows us the complete pulp regeneration of mature teeth, in which advantage is taken of the differentiation capacity of residual pulp stem cells. These cells are capable of generating a highly vascularized living tissue rich in connective tissue, which colonizes the available pulp space. However, until the completion of this review, no method has been reported in the literature as viable for clinical application in humans.En la actualidad la endodoncia convencional es un procedimiento que presenta variedad de efectos secundarios a futuro, por eso se desarrollan terapias de regeneración y/o revascularización pulpar, que normalmente se realizan en dientes permanentes inmaduros con el fin de generar tratamientos más conservadores. En los últimos años y en los avances recientes en la ingeniería de tejidos se ha registrado un camino para la terapia pulpar lo cual permite la regeneración pulpar completa de los dientes maduros, en la cual se toma ventaja de la capacidad de diferenciación de las células madre pulpares residuales. Estas células son capaces de generar un tejido vivo altamente vascularizado y rico en tejido conjuntivo, el cual coloniza el espacio pulpar disponible. Sin embargo y hasta la realización de esta revisión de la literatura, ningún método se ha reportado como viable para su aplicación clínica en humanos.Odontólogo(a)PregradoPresencialMonografíaspaUniversidad Antonio NariñoOdontologíaFacultad de OdontologíaArmeniaRevascularizaciónRevitalización pulparCelulas madreCélulas madre de la pulpa dentalRegeneración pulparDientes madurosDientes adultosRegeneración endodónticaIngeniería de tejidos600RevascularizationPulp revitalizationStem cellDental pulp stem cellPulp regenerationMature teethAdult teethEndodontic regenerationTissue engineeringRegeneración pulpar en dientes maduros usando células madre, una revisión narrativaTrabajo de grado (Pregrado y/o Especialización)http://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/version/c_970fb48d4fbd8a85EspecializadaORIGINAL2021_JuanJoseMartinez.pdf2021_JuanJoseMartinez.pdfTrabajo completoapplication/pdf400843https://repositorio.uan.edu.co/bitstreams/7f1020f1-f19a-4f19-a6e4-e7fec7688418/downloadbd8dfbee3a2c5e41eacf345254d2381aMD532021_JuanJoseMartinez_Autorizacion.pdf2021_JuanJoseMartinez_Autorizacion.pdfAutorizacion consultaapplication/pdf514566https://repositorio.uan.edu.co/bitstreams/833f12fc-0757-4310-a3b6-8004e51b61a7/download7df755f9773fc1d217f67b4bb2ec3f3eMD512021_JuanJoseMartinez_Acta.pdf2021_JuanJoseMartinez_Acta.pdfActa sustentaciónimage/jpeg1190920https://repositorio.uan.edu.co/bitstreams/fe4bc492-9a44-4d8d-b047-da01ca32203a/download57a3d5beee9039ad16a1f51424a19112MD52123456789/6358oai:repositorio.uan.edu.co:123456789/63582024-10-09 22:54:07.085https://creativecommons.org/licenses/by-nc-nd/4.0/Acceso abiertoopen.accesshttps://repositorio.uan.edu.coRepositorio Institucional UANalertas.repositorio@uan.edu.co

Publicaciones similares