Evaluación de la enzima tripanotión reductasa del parásito Trypanosoma cruzi frente a moléculas tipo carbenos N-Heterocíclicos empleando técnicas computacionales.
The Trypanosoma cruzi parasite is responsible for Chagas disease, mostly found in areas with scarce resources, which limits research focused on the development of non-toxic treatments for patients, in comparison with the drugs currently used: Nifurtimox and Benznidazole, which have adverse effects.
- Autores:
-
Melo Marquez, Angie
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2023
- Institución:
- Universidad Antonio Nariño
- Repositorio:
- Repositorio UAN
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.uan.edu.co:123456789/9104
- Acceso en línea:
- http://repositorio.uan.edu.co/handle/123456789/9104
- Palabra clave:
- Trypanosoma cruzi
Compuestos N-heterocíclicos
enfermedad de Chagas
Trypanothione reductase
propiedades ADMET
574.38 M528
Trypanosoma cruzi
N-heterocyclic compounds
Chagas disease
Trypanothione reductase
ADMET properties
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
| Summary: | The Trypanosoma cruzi parasite is responsible for Chagas disease, mostly found in areas with scarce resources, which limits research focused on the development of non-toxic treatments for patients, in comparison with the drugs currently used: Nifurtimox and Benznidazole, which have adverse effects. |
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