Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra

Stress is a risk factor for several organic diseases including psychiatric disorders such as anxiety, depression, and substances use disorders, among others. Alcohol is a widely used substance in the world and its acute effects on a behavioral level are known. The effect of environmental stress and...

Full description

Autores:
Franco Restrepo, Juan Esteban
Tipo de recurso:
Doctoral thesis
Fecha de publicación:
2021
Institución:
Universidad Antonio Nariño
Repositorio:
Repositorio UAN
Idioma:
spa
OAI Identifier:
oai:repositorio.uan.edu.co:123456789/5090
Acceso en línea:
http://repositorio.uan.edu.co/handle/123456789/5090
Palabra clave:
Pez Cebra
Cafeina
Etanol
Estrés
Zebra fish
Caffein
Ethanol
Stress
Rights
openAccess
License
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
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repository_id_str
dc.title.es_ES.fl_str_mv Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
title Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
spellingShingle Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
Pez Cebra
Cafeina
Etanol
Estrés
Zebra fish
Caffein
Ethanol
Stress
title_short Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
title_full Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
title_fullStr Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
title_full_unstemmed Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
title_sort Efectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez Cebra
dc.creator.fl_str_mv Franco Restrepo, Juan Esteban
dc.contributor.advisor.spa.fl_str_mv Vargas Vargas, Rafael Antonio
Forero Garzón, Diego Alexander
dc.contributor.author.spa.fl_str_mv Franco Restrepo, Juan Esteban
dc.subject.es_ES.fl_str_mv Pez Cebra
Cafeina
Etanol
Estrés
topic Pez Cebra
Cafeina
Etanol
Estrés
Zebra fish
Caffein
Ethanol
Stress
dc.subject.keyword.es_ES.fl_str_mv Zebra fish
Caffein
Ethanol
Stress
description Stress is a risk factor for several organic diseases including psychiatric disorders such as anxiety, depression, and substances use disorders, among others. Alcohol is a widely used substance in the world and its acute effects on a behavioral level are known. The effect of environmental stress and substances on behavior has been studied separately. Short and long-term stress in zebrafish can generate alterations in the CNS affecting anxiety levels in different behavioral tests such as locomotion, social, learning and memory behavior. However, in the brain, the molecular effects of environmental stress are poorly understood in association with alcohol and other substances such as caffeine, consumed throughout the world.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-10-26T21:25:48Z
dc.date.available.none.fl_str_mv 2021-10-26T21:25:48Z
dc.date.issued.spa.fl_str_mv 2021-06-28
dc.type.spa.fl_str_mv Tesis y disertaciones (Maestría y/o Doctorado)
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dc.type.local.spa.fl_str_mv Tesis/Trabajo de grado - Monografía - Doctorado
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dc.identifier.uri.none.fl_str_mv http://repositorio.uan.edu.co/handle/123456789/5090
dc.identifier.bibliographicCitation.spa.fl_str_mv Abreu, M., Koakoski, G., Ferreira, D., Oliveira, T., Rosa, J., & Gusso, D. et al. (2014). Diazepam and Fluoxetine Decrease the Stress Response in Zebrafish. Plos ONE, 9(7), e103232. doi: 10.1371/journal.pone.0103232
Alazizi, A., Liu, M., Williams, F., Kurogi, K., Sakakibara, Y., Suiko, M., & Liu, M. (2011). Identification, characterization, and ontogenic study of a catechol O-methyltransferase from zebrafish. Aquatic Toxicology, 102(1-2), 18-23. doi: 10.1016/j.aquatox.2010.12.016
Asakawa, K., Suster, M. L., Mizusawa, K., Nagayoshi, S., Kotani, T., Urasaki, A.,Kishimoto, Y., Hibi, M. and Kawakami, K. (2008). Genetic dissection of neuralcircuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish.Proc. Natl. Acad. Sci. USA 105, 1255-1260.
Barreto-Valer, K., López-Bellido, R., Macho Sánchez-Simón, F., & Rodríguez, R. (2012). Modulation by Cocaine of Dopamine Receptors through miRNA-133b in Zebrafish Embryos. Plos ONE, 7(12), e52701. doi: 10.1371/journal.pone.0052701
Cachat J, Canavello P, Elegante M, Bartels B, Hart P, Bergner C, et al. Modeling withdrawal syndrome in zebrafish. Behav Brain Res. 208.2 (2010), pp. 371-376. https://doi.org/10.1016/j.bbr.2009.12.004
Castaño, G., Sierra, G., Sánchez, D., Torres, Y., Salas, C., & Buitrago, C. (2017). Trastornos mentales y consumo de drogas en la población víctima del conflicto armado en tres ciudades de Colombia. Biomédica, 38, 77–92.doi:10.7705/biomedica.v38i0.3890
Daré, L., Bruand, P., Gérard, D., Marin, B., Lameyre, V., Boumédiène, F., & Preux, P. (2019). Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis. BMC Public Health, 19(1). doi: 10.1186/s12889-019-6623-6
Echevarria DJ, Hammack CM, Jouandot DJ, Toms CN. Does Acute Alcohol Exposure Modulate Aggressive Behaviors in the Zebrafish (Danio rerio), or is the Bark Worse than the Bite? Int J Comp Psychol. 23 (2010). https://escholarship.org/uc/item/2px3t3jc
Eddins, D., Petro, A., Williams, P., Cerutti, D., & Levin, E. (2008). Nicotine effects on learning in zebrafish: the role of dopaminergic systems. Psychopharmacology, 202(1-3), 103-109. doi: 10.1007/s00213-008-1287-4
Emerson, A. J., Kappenman, D. P., Ronan, P. J., Renner, K. J., and Summers, C. H. (2000). Stress induces rapid changes in serotonergic activity: restraint and exertion. Behav. Brain Res. 111, 83–92. doi: 10.1016/s0166- 4328(00) 00143-1
dc.identifier.instname.spa.fl_str_mv instname:Universidad Antonio Nariño
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identifier_str_mv Abreu, M., Koakoski, G., Ferreira, D., Oliveira, T., Rosa, J., & Gusso, D. et al. (2014). Diazepam and Fluoxetine Decrease the Stress Response in Zebrafish. Plos ONE, 9(7), e103232. doi: 10.1371/journal.pone.0103232
Alazizi, A., Liu, M., Williams, F., Kurogi, K., Sakakibara, Y., Suiko, M., & Liu, M. (2011). Identification, characterization, and ontogenic study of a catechol O-methyltransferase from zebrafish. Aquatic Toxicology, 102(1-2), 18-23. doi: 10.1016/j.aquatox.2010.12.016
Asakawa, K., Suster, M. L., Mizusawa, K., Nagayoshi, S., Kotani, T., Urasaki, A.,Kishimoto, Y., Hibi, M. and Kawakami, K. (2008). Genetic dissection of neuralcircuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish.Proc. Natl. Acad. Sci. USA 105, 1255-1260.
Barreto-Valer, K., López-Bellido, R., Macho Sánchez-Simón, F., & Rodríguez, R. (2012). Modulation by Cocaine of Dopamine Receptors through miRNA-133b in Zebrafish Embryos. Plos ONE, 7(12), e52701. doi: 10.1371/journal.pone.0052701
Cachat J, Canavello P, Elegante M, Bartels B, Hart P, Bergner C, et al. Modeling withdrawal syndrome in zebrafish. Behav Brain Res. 208.2 (2010), pp. 371-376. https://doi.org/10.1016/j.bbr.2009.12.004
Castaño, G., Sierra, G., Sánchez, D., Torres, Y., Salas, C., & Buitrago, C. (2017). Trastornos mentales y consumo de drogas en la población víctima del conflicto armado en tres ciudades de Colombia. Biomédica, 38, 77–92.doi:10.7705/biomedica.v38i0.3890
Daré, L., Bruand, P., Gérard, D., Marin, B., Lameyre, V., Boumédiène, F., & Preux, P. (2019). Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis. BMC Public Health, 19(1). doi: 10.1186/s12889-019-6623-6
Echevarria DJ, Hammack CM, Jouandot DJ, Toms CN. Does Acute Alcohol Exposure Modulate Aggressive Behaviors in the Zebrafish (Danio rerio), or is the Bark Worse than the Bite? Int J Comp Psychol. 23 (2010). https://escholarship.org/uc/item/2px3t3jc
Eddins, D., Petro, A., Williams, P., Cerutti, D., & Levin, E. (2008). Nicotine effects on learning in zebrafish: the role of dopaminergic systems. Psychopharmacology, 202(1-3), 103-109. doi: 10.1007/s00213-008-1287-4
Emerson, A. J., Kappenman, D. P., Ronan, P. J., Renner, K. J., and Summers, C. H. (2000). Stress induces rapid changes in serotonergic activity: restraint and exertion. Behav. Brain Res. 111, 83–92. doi: 10.1016/s0166- 4328(00) 00143-1
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dc.publisher.program.spa.fl_str_mv Doctorado en Ciencias de la salud
dc.publisher.faculty.spa.fl_str_mv Facultad de Medicina
dc.publisher.campus.spa.fl_str_mv Bogotá - Circunvalar
institution Universidad Antonio Nariño
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spelling Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)Acceso abiertohttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Vargas Vargas, Rafael AntonioForero Garzón, Diego AlexanderFranco Restrepo, Juan Esteban0000-0001-5702-9240https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001090194https://scholar.google.es/citations?user=gSvbdpgAAAAJ&hl=es129716189122021-10-26T21:25:48Z2021-10-26T21:25:48Z2021-06-28http://repositorio.uan.edu.co/handle/123456789/5090Abreu, M., Koakoski, G., Ferreira, D., Oliveira, T., Rosa, J., & Gusso, D. et al. (2014). Diazepam and Fluoxetine Decrease the Stress Response in Zebrafish. Plos ONE, 9(7), e103232. doi: 10.1371/journal.pone.0103232Alazizi, A., Liu, M., Williams, F., Kurogi, K., Sakakibara, Y., Suiko, M., & Liu, M. (2011). Identification, characterization, and ontogenic study of a catechol O-methyltransferase from zebrafish. Aquatic Toxicology, 102(1-2), 18-23. doi: 10.1016/j.aquatox.2010.12.016Asakawa, K., Suster, M. L., Mizusawa, K., Nagayoshi, S., Kotani, T., Urasaki, A.,Kishimoto, Y., Hibi, M. and Kawakami, K. (2008). Genetic dissection of neuralcircuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish.Proc. Natl. Acad. Sci. USA 105, 1255-1260.Barreto-Valer, K., López-Bellido, R., Macho Sánchez-Simón, F., & Rodríguez, R. (2012). Modulation by Cocaine of Dopamine Receptors through miRNA-133b in Zebrafish Embryos. Plos ONE, 7(12), e52701. doi: 10.1371/journal.pone.0052701Cachat J, Canavello P, Elegante M, Bartels B, Hart P, Bergner C, et al. Modeling withdrawal syndrome in zebrafish. Behav Brain Res. 208.2 (2010), pp. 371-376. https://doi.org/10.1016/j.bbr.2009.12.004Castaño, G., Sierra, G., Sánchez, D., Torres, Y., Salas, C., & Buitrago, C. (2017). Trastornos mentales y consumo de drogas en la población víctima del conflicto armado en tres ciudades de Colombia. Biomédica, 38, 77–92.doi:10.7705/biomedica.v38i0.3890Daré, L., Bruand, P., Gérard, D., Marin, B., Lameyre, V., Boumédiène, F., & Preux, P. (2019). Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis. BMC Public Health, 19(1). doi: 10.1186/s12889-019-6623-6Echevarria DJ, Hammack CM, Jouandot DJ, Toms CN. Does Acute Alcohol Exposure Modulate Aggressive Behaviors in the Zebrafish (Danio rerio), or is the Bark Worse than the Bite? Int J Comp Psychol. 23 (2010). https://escholarship.org/uc/item/2px3t3jcEddins, D., Petro, A., Williams, P., Cerutti, D., & Levin, E. (2008). Nicotine effects on learning in zebrafish: the role of dopaminergic systems. Psychopharmacology, 202(1-3), 103-109. doi: 10.1007/s00213-008-1287-4Emerson, A. J., Kappenman, D. P., Ronan, P. J., Renner, K. J., and Summers, C. H. (2000). Stress induces rapid changes in serotonergic activity: restraint and exertion. Behav. Brain Res. 111, 83–92. doi: 10.1016/s0166- 4328(00) 00143-1instname:Universidad Antonio Nariñoreponame:Repositorio Institucional UANrepourl:https://repositorio.uan.edu.co/Stress is a risk factor for several organic diseases including psychiatric disorders such as anxiety, depression, and substances use disorders, among others. Alcohol is a widely used substance in the world and its acute effects on a behavioral level are known. The effect of environmental stress and substances on behavior has been studied separately. Short and long-term stress in zebrafish can generate alterations in the CNS affecting anxiety levels in different behavioral tests such as locomotion, social, learning and memory behavior. However, in the brain, the molecular effects of environmental stress are poorly understood in association with alcohol and other substances such as caffeine, consumed throughout the world.El estrés es un factor de riesgo para diversas enfermedades orgánicas incluyendo trastornos psiquiátricos como la ansiedad, depresión, consumo de sustancias adictivas entre otros. El alcohol es una sustancia ampliamente usada en el mundo y sus efectos agudos a nivel comportamental son conocidos. El efecto del estrés ambiental y sustancias sobre el comportamiento se ha estudiado por separado. El estrés a corto y largo plazo en el pez cebra puede generar alteraciones en el SNC afectando los niveles de ansiedad en diferentes pruebas del comportamiento tales como la conducta motora, social, aprendizaje y memoria. Sin embargo, a nivel molecular en el cerebro son poco conocidos los efectos del estrés ambiental en conjunto con el alcohol y otras sustancias como la cafeína, consumidas en todo el mundo.Doctor(a) en Ciencias de la saludDoctoradoPresencialProyectospaUniversidad Antonio NariñoDoctorado en Ciencias de la saludFacultad de MedicinaBogotá - CircunvalarPez CebraCafeinaEtanolEstrésZebra fishCaffeinEthanolStressEfectos comportamentales y moleculares del estrés agudo, etanol y la cafeína en el pez CebraTesis y disertaciones (Maestría y/o Doctorado)http://purl.org/coar/resource_type/c_db06http://purl.org/coar/version/c_970fb48d4fbd8a85Tesis/Trabajo de grado - Monografía - DoctoradoEspecializadaORIGINAL2021JuanEstebanFrancoRestrepo.pdf2021JuanEstebanFrancoRestrepo.pdfTesis Doctoralapplication/pdf12620740https://repositorio.uan.edu.co/bitstreams/b706f776-4115-4370-95b5-d4f2b713dd55/downloade9bb8210c1b94086df897b1271d40ec3MD512021ActadeSustentación.pdf2021ActadeSustentación.pdfActa de 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