Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review

La fibrina rica en plaquetas y leucocitos (PRF-L) pertenece a una nueva generación de concentrados plaquetarios orientados a una preparación simplificada sin manipulación bioquímica de la sangre. Se ha demostrado que funciona como andamio, proporcionando una posición espacialmente correcta para la u...

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Autores:
Tovar Pérez, Elvia Carolina
Sanabria Contreras, Litza Yohanna
Tipo de recurso:
Trabajo de grado de pregrado
Fecha de publicación:
2022
Institución:
Universidad Santo Tomás
Repositorio:
Repositorio Institucional USTA
Idioma:
spa
OAI Identifier:
oai:repository.usta.edu.co:11634/44871
Acceso en línea:
http://hdl.handle.net/11634/44871
Palabra clave:
Platelet-richfibrin
Endodontics
Clinical applications
Factores de coagulación sanguínea
Proteinas de la sangre
Pulpa dental - enfermedades
Fibrina rica en plaquetas
Endodoncia
Aplicaciones clínicas
Rights
openAccess
License
Atribución 2.5 Colombia
id SANTTOMAS2_c2881ec6c60c4b9cd39f6f3dbed2485a
oai_identifier_str oai:repository.usta.edu.co:11634/44871
network_acronym_str SANTTOMAS2
network_name_str Repositorio Institucional USTA
repository_id_str
dc.title.spa.fl_str_mv Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
title Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
spellingShingle Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
Platelet-richfibrin
Endodontics
Clinical applications
Factores de coagulación sanguínea
Proteinas de la sangre
Pulpa dental - enfermedades
Fibrina rica en plaquetas
Endodoncia
Aplicaciones clínicas
title_short Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
title_full Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
title_fullStr Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
title_full_unstemmed Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
title_sort Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping Review
dc.creator.fl_str_mv Tovar Pérez, Elvia Carolina
Sanabria Contreras, Litza Yohanna
dc.contributor.advisor.none.fl_str_mv Chaves, Angela María
Bastidas Neira, Harrizon
Jiménez, Oscar Mauricio
dc.contributor.author.none.fl_str_mv Tovar Pérez, Elvia Carolina
Sanabria Contreras, Litza Yohanna
dc.subject.keyword.spa.fl_str_mv Platelet-richfibrin
Endodontics
Clinical applications
topic Platelet-richfibrin
Endodontics
Clinical applications
Factores de coagulación sanguínea
Proteinas de la sangre
Pulpa dental - enfermedades
Fibrina rica en plaquetas
Endodoncia
Aplicaciones clínicas
dc.subject.lemb.spa.fl_str_mv Factores de coagulación sanguínea
Proteinas de la sangre
Pulpa dental - enfermedades
dc.subject.proposal.spa.fl_str_mv Fibrina rica en plaquetas
Endodoncia
Aplicaciones clínicas
description La fibrina rica en plaquetas y leucocitos (PRF-L) pertenece a una nueva generación de concentrados plaquetarios orientados a una preparación simplificada sin manipulación bioquímica de la sangre. Se ha demostrado que funciona como andamio, proporcionando una posición espacialmente correcta para la ubicación de las células, regulando la diferenciación, la proliferación y/o el metabolismo de las células madre en el campo de la endodoncia regenerativa. Objetivo: Determinar mediante un scoping review las aplicaciones de la fibrina rica en plaquetas y leucocitos en los diferentes procedimientos endodónticos documentados en la literatura. Materiales y métodos: Se diseñó una estrategia de búsqueda de artículos de los últimos 10 años que describieran la aplicación del PRF-L en los diferentes procedimientos endodónticos encontrados en las bases de datos Pubmed, Epistemonikos, Scielo, Cochrane. La evaluación de la calidad metodológica, riesgo de sesgo y la extracción de datos se realizaron de forma independiente y por duplicado. Los resultados se expresaron utilizando la guía PRISMA. Resultados: Se seleccionaron 18 estudios de los cuales seis fueron reportes de caso, tres series de casos, cuatro estudios prospectivos, un ensayo clínico aleatorizado, un estudio in vivo, un estudio piloto, un estudio in vitro y un estudio de cohorte controlado retrospectivo. Las aplicaciones del PRF-L reportadas en la literatura para procedimientos endodónticos son regeneración pulpar, cirugía perirradicular, recubrimiento pulpar directo y pulpotomía Conclusiones: El resultado exitoso de los REP se evalúa o mide como la capacidad de estos para lograr cierre apical, cicatrización de la lesión periapical, aumento en la longitud radicular y/o el engrosamiento de la pared dentinaria.
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-06-10T14:01:34Z
dc.date.available.none.fl_str_mv 2022-06-10T14:01:34Z
dc.date.issued.none.fl_str_mv 2022-06-07
dc.type.local.spa.fl_str_mv Trabajo de grado
dc.type.version.none.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.category.spa.fl_str_mv Formación de Recurso Humano para la Ctel: Trabajo de grado de Especialización
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.drive.none.fl_str_mv info:eu-repo/semantics/bachelorThesis
format http://purl.org/coar/resource_type/c_7a1f
status_str acceptedVersion
dc.identifier.citation.spa.fl_str_mv Sanabria Contreras, L.Y. Tovar Perez, E.C. (2022). Aplicabilidad de la fibrina rica en plaquetas y leucocitos en los diferentes procedimientos endodonticos- Scoping Review. [Trabajo de especialización] Universidad Santo Tomás. Bucaramanga, Colombia
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/11634/44871
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad Santo Tomás
dc.identifier.instname.spa.fl_str_mv instname:Universidad Santo Tomás
dc.identifier.repourl.spa.fl_str_mv repourl:https://repository.usta.edu.co
identifier_str_mv Sanabria Contreras, L.Y. Tovar Perez, E.C. (2022). Aplicabilidad de la fibrina rica en plaquetas y leucocitos en los diferentes procedimientos endodonticos- Scoping Review. [Trabajo de especialización] Universidad Santo Tomás. Bucaramanga, Colombia
reponame:Repositorio Institucional Universidad Santo Tomás
instname:Universidad Santo Tomás
repourl:https://repository.usta.edu.co
url http://hdl.handle.net/11634/44871
dc.language.iso.spa.fl_str_mv spa
language spa
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spelling Chaves, Angela MaríaBastidas Neira, HarrizonJiménez, Oscar MauricioTovar Pérez, Elvia CarolinaSanabria Contreras, Litza Yohanna2022-06-10T14:01:34Z2022-06-10T14:01:34Z2022-06-07Sanabria Contreras, L.Y. Tovar Perez, E.C. (2022). Aplicabilidad de la fibrina rica en plaquetas y leucocitos en los diferentes procedimientos endodonticos- Scoping Review. [Trabajo de especialización] Universidad Santo Tomás. Bucaramanga, Colombiahttp://hdl.handle.net/11634/44871reponame:Repositorio Institucional Universidad Santo Tomásinstname:Universidad Santo Tomásrepourl:https://repository.usta.edu.coLa fibrina rica en plaquetas y leucocitos (PRF-L) pertenece a una nueva generación de concentrados plaquetarios orientados a una preparación simplificada sin manipulación bioquímica de la sangre. Se ha demostrado que funciona como andamio, proporcionando una posición espacialmente correcta para la ubicación de las células, regulando la diferenciación, la proliferación y/o el metabolismo de las células madre en el campo de la endodoncia regenerativa. Objetivo: Determinar mediante un scoping review las aplicaciones de la fibrina rica en plaquetas y leucocitos en los diferentes procedimientos endodónticos documentados en la literatura. Materiales y métodos: Se diseñó una estrategia de búsqueda de artículos de los últimos 10 años que describieran la aplicación del PRF-L en los diferentes procedimientos endodónticos encontrados en las bases de datos Pubmed, Epistemonikos, Scielo, Cochrane. La evaluación de la calidad metodológica, riesgo de sesgo y la extracción de datos se realizaron de forma independiente y por duplicado. Los resultados se expresaron utilizando la guía PRISMA. Resultados: Se seleccionaron 18 estudios de los cuales seis fueron reportes de caso, tres series de casos, cuatro estudios prospectivos, un ensayo clínico aleatorizado, un estudio in vivo, un estudio piloto, un estudio in vitro y un estudio de cohorte controlado retrospectivo. Las aplicaciones del PRF-L reportadas en la literatura para procedimientos endodónticos son regeneración pulpar, cirugía perirradicular, recubrimiento pulpar directo y pulpotomía Conclusiones: El resultado exitoso de los REP se evalúa o mide como la capacidad de estos para lograr cierre apical, cicatrización de la lesión periapical, aumento en la longitud radicular y/o el engrosamiento de la pared dentinaria.Leucocyte platelet-rich fibrin (L-PRF) is part of a new generation of platelet concentrates aimed at a simplified preparation with no biochemical manipulation of blood. It has been proven that it works as a scaffolding, providing a spatially-correct position of the location of cells, regulating the differentiation, proliferation, and/or metabolism of stem cells in the field of regenerative endodontics. Objective: To conduct a scoping review to the application of leucocyte platelet-richfibrin L-PRF in endodontic procedures documented in the literature. Materials and methods: A strategy was designed to search for articles in the last 10 years in which the L-PRF application were described in the endodontic procedures found on the following databases: Pubmed, Epistemonikos, Scielo, and Cochrane. The methodological quality assessment, risk of bias, and the extraction of data were conducted independently and per duplicate. The results were stated using the PRISMA guide. Results: 18 studies were selected, of which 6 were case reports, three case series, four prospective studies, one randomised clinical assay, one in vivo study, one pilot study, one in vitro study, and one retrospective controlled cohort study. The L-PRF applications reported in the literature for endodontic procedures are pulp regeneration, periradicular surgery, direct pulp capping, and pulpotomy. Conclusions: The successful REP result is evaluated or measured as their capacity to achieve apical closure, scarring of periapical lesion, increase in radicular length, and/or thickening of dentinal wall.Especialista en Endodonciahttp://www.ustabuca.edu.co/ustabmanga/presentacionEspecializaciónapplication/pdfspaUniversidad Santo TomásEspecialización EndodonciaFacultad de OdontologíaAtribución 2.5 Colombiahttp://creativecommons.org/licenses/by/2.5/co/Abierto (Texto Completo)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Aplicabilidad de la fibrina rica en plaquetas y leucitos en los diferentes procedimientos endodonticos-Scoping ReviewPlatelet-richfibrinEndodonticsClinical applicationsFactores de coagulación sanguíneaProteinas de la sangrePulpa dental - enfermedadesFibrina rica en plaquetasEndodonciaAplicaciones clínicasTrabajo de gradoinfo:eu-repo/semantics/acceptedVersionFormación de Recurso Humano para la Ctel: Trabajo de grado de Especializaciónhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesisCRAI-USTA BucaramangaAlmutairi, W., Yassen, G. 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