Deep brain stimulation modeling for several anatomical and electrical considerations

Deep Brain Stimulation (DBS) is a clinical treatment for Parkinson disease symptoms. DBS consists in the implantation of a stimulation electrode into the Subthalamic nucleus (STN) for the excitation of specific regions inside the STN. The stimulation potential has a few parameters that should be adj...

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Autores:
Torres-Valencia, Cristian Alejandro
Daza-Santacoloma, Genaro
Álvarez-López, Mauricio Alexander
Orozco-Gutiérrez, Álvaro Ángel
Tipo de recurso:
Fecha de publicación:
2014
Institución:
Universidad Santo Tomás
Repositorio:
Repositorio Institucional USTA
Idioma:
spa
OAI Identifier:
oai:repository.usta.edu.co:11634/36116
Acceso en línea:
http://revistas.ustabuca.edu.co/index.php/ITECKNE/article/view/723
http://hdl.handle.net/11634/36116
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Copyright (c) 2018 ITECKNE
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repository_id_str
spelling Torres-Valencia, Cristian AlejandroDaza-Santacoloma, GenaroÁlvarez-López, Mauricio AlexanderOrozco-Gutiérrez, Álvaro Ángel2021-09-24T13:17:26Z2021-09-24T13:17:26Z2014-12-31http://revistas.ustabuca.edu.co/index.php/ITECKNE/article/view/72310.15332/iteckne.v11i2.723http://hdl.handle.net/11634/36116Deep Brain Stimulation (DBS) is a clinical treatment for Parkinson disease symptoms. DBS consists in the implantation of a stimulation electrode into the Subthalamic nucleus (STN) for the excitation of specific regions inside the STN. The stimulation potential has a few parameters that should be adjusted in order to achieve the desired treatment effect. The adjust is performed by the neurologist in several sessions with the patients and is not an exact procedure. In recent years there have been several works on the construction of propagation models of DBS, including head geometries and medium properties in order to visualize the possible effects of DBS while the stimulation parameters are adjusted. This work presents the construction of propagation models using the Finite Element Method (FEM) for the solution of Laplace or Poisson equations that govern the propagation phenomena. By the construction of these models, the shape and magnitude of the electric propagation inside the objective structures can be obtained.La estimulación cerebral profunda (DBS) es una  terapia  quirúrgica  validada  para  el  tratamiento de los  síntomas  asociados  con  la  enfermedad  de  Parkinson. Consiste en la implantación de un electrodo de estimulación generalmente en la región del núcleo subtalámico (STN), con el cual se excitan regiones específicas a partir de un potencial eléctrico con ciertos parámetros específicos. El ajuste de los parámetros de estimulación es un proceso realizado por parte del neurólogo y puede tardar varios meses hasta alcanzar los resultados deseados. Es por esto que en años recientes se ha estudiado la construcción de modelos de propagación eléctrica de las estructuras objetivo de la DBS con el fin de visualizar los posibles resultados de la distribución de campo eléctrico y la activación del tejido cerebral que sirven como guía  para  el  ajuste  de  los parámetros  de  estimulación, optimizando el procedimiento de configuración. En este trabajo  se  presenta  la  comparación  de  modelos  de  simulación que incluyen la definición de geometrías complejas  representando  diferentes  estructuras  cerebrales con propiedades de diferentes tejidos, con los cuales se obtienen los patrones de propagación eléctrica cerebral por medio del método de elementos finitos (FEM) aplicado a la solución de las ecuaciones de Laplace y Poisson.application/pdfspaUniversidad Santo Tomás. Seccional Bucaramangahttp://revistas.ustabuca.edu.co/index.php/ITECKNE/article/view/723/569ITECKNE; Vol 11 No 2 (2014); 140-148ITECKNE; Vol 11 No 2 (2014); 140-1482339-34831692-1798Copyright (c) 2018 ITECKNEhttp://purl.org/coar/access_right/c_abf2Deep brain stimulation modeling for several anatomical and electrical considerationsModelos de estimulación cerebral profunda para diferentes consideraciones anatómicas y eléctricasinfo:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb111634/36116oai:repository.usta.edu.co:11634/361162023-07-14 16:20:35.143metadata only accessRepositorio Universidad Santo Tomásnoreply@usta.edu.co
dc.title.spa.fl_str_mv Deep brain stimulation modeling for several anatomical and electrical considerations
dc.title.alternative.eng.fl_str_mv Modelos de estimulación cerebral profunda para diferentes consideraciones anatómicas y eléctricas
title Deep brain stimulation modeling for several anatomical and electrical considerations
spellingShingle Deep brain stimulation modeling for several anatomical and electrical considerations
title_short Deep brain stimulation modeling for several anatomical and electrical considerations
title_full Deep brain stimulation modeling for several anatomical and electrical considerations
title_fullStr Deep brain stimulation modeling for several anatomical and electrical considerations
title_full_unstemmed Deep brain stimulation modeling for several anatomical and electrical considerations
title_sort Deep brain stimulation modeling for several anatomical and electrical considerations
dc.creator.fl_str_mv Torres-Valencia, Cristian Alejandro
Daza-Santacoloma, Genaro
Álvarez-López, Mauricio Alexander
Orozco-Gutiérrez, Álvaro Ángel
dc.contributor.author.none.fl_str_mv Torres-Valencia, Cristian Alejandro
Daza-Santacoloma, Genaro
Álvarez-López, Mauricio Alexander
Orozco-Gutiérrez, Álvaro Ángel
description Deep Brain Stimulation (DBS) is a clinical treatment for Parkinson disease symptoms. DBS consists in the implantation of a stimulation electrode into the Subthalamic nucleus (STN) for the excitation of specific regions inside the STN. The stimulation potential has a few parameters that should be adjusted in order to achieve the desired treatment effect. The adjust is performed by the neurologist in several sessions with the patients and is not an exact procedure. In recent years there have been several works on the construction of propagation models of DBS, including head geometries and medium properties in order to visualize the possible effects of DBS while the stimulation parameters are adjusted. This work presents the construction of propagation models using the Finite Element Method (FEM) for the solution of Laplace or Poisson equations that govern the propagation phenomena. By the construction of these models, the shape and magnitude of the electric propagation inside the objective structures can be obtained.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014-12-31
dc.date.accessioned.none.fl_str_mv 2021-09-24T13:17:26Z
dc.date.available.none.fl_str_mv 2021-09-24T13:17:26Z
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.drive.none.fl_str_mv info:eu-repo/semantics/article
dc.identifier.none.fl_str_mv http://revistas.ustabuca.edu.co/index.php/ITECKNE/article/view/723
10.15332/iteckne.v11i2.723
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/11634/36116
url http://revistas.ustabuca.edu.co/index.php/ITECKNE/article/view/723
http://hdl.handle.net/11634/36116
identifier_str_mv 10.15332/iteckne.v11i2.723
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv http://revistas.ustabuca.edu.co/index.php/ITECKNE/article/view/723/569
dc.relation.citationissue.spa.fl_str_mv ITECKNE; Vol 11 No 2 (2014); 140-148
dc.relation.citationissue.eng.fl_str_mv ITECKNE; Vol 11 No 2 (2014); 140-148
dc.relation.citationissue.none.fl_str_mv 2339-3483
1692-1798
dc.rights.eng.fl_str_mv Copyright (c) 2018 ITECKNE
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv Copyright (c) 2018 ITECKNE
http://purl.org/coar/access_right/c_abf2
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.eng.fl_str_mv Universidad Santo Tomás. Seccional Bucaramanga
institution Universidad Santo Tomás
repository.name.fl_str_mv Repositorio Universidad Santo Tomás
repository.mail.fl_str_mv noreply@usta.edu.co
_version_ 1800800455665647616

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