Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos
La contaminación del agua es un problema serio para la salud y el medio ambiente, lo que hace crucial monitorear su calidad. Los métodos tradicionales como la espectroscopia de absorción atómica y la espectrometría de plasma son efectivos pero costosos y lentos. En respuesta, se han desarrollado mét...
- Autores:
-
Pinzón Troncoso, Jennifer Alejandra
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2024
- Institución:
- Universidad Santo Tomás
- Repositorio:
- Repositorio Institucional USTA
- Idioma:
- spa
- OAI Identifier:
- oai:repository.usta.edu.co:11634/55061
- Acceso en línea:
- http://hdl.handle.net/11634/55061
- Palabra clave:
- Fluorescent sensors
Chemosensors
Curcumin analogs
Transition metals
Espectrometría
Detección de contaminantes
Espectroscopia Infrarroja
Espectrofotometría de ultravioleta visible
Pruebas ecotoxicológicas
Sensores fluorescentes
Análogos de curcumina
Quimiosensores
Metales de transición
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 2.5 Colombia
| id |
SANTOTOMAS_54ef8ffd0ea42467e111b51dd6aa7649 |
|---|---|
| oai_identifier_str |
oai:repository.usta.edu.co:11634/55061 |
| network_acronym_str |
SANTOTOMAS |
| network_name_str |
Repositorio Institucional USTA |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| title |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| spellingShingle |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos Fluorescent sensors Chemosensors Curcumin analogs Transition metals Espectrometría Detección de contaminantes Espectroscopia Infrarroja Espectrofotometría de ultravioleta visible Pruebas ecotoxicológicas Sensores fluorescentes Análogos de curcumina Quimiosensores Metales de transición |
| title_short |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| title_full |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| title_fullStr |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| title_full_unstemmed |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| title_sort |
Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos |
| dc.creator.fl_str_mv |
Pinzón Troncoso, Jennifer Alejandra |
| dc.contributor.advisor.none.fl_str_mv |
Osorio Martínez, Carlos Alberto |
| dc.contributor.author.none.fl_str_mv |
Pinzón Troncoso, Jennifer Alejandra |
| dc.subject.keyword.spa.fl_str_mv |
Fluorescent sensors Chemosensors Curcumin analogs Transition metals |
| topic |
Fluorescent sensors Chemosensors Curcumin analogs Transition metals Espectrometría Detección de contaminantes Espectroscopia Infrarroja Espectrofotometría de ultravioleta visible Pruebas ecotoxicológicas Sensores fluorescentes Análogos de curcumina Quimiosensores Metales de transición |
| dc.subject.lemb.spa.fl_str_mv |
Espectrometría Detección de contaminantes Espectroscopia Infrarroja Espectrofotometría de ultravioleta visible Pruebas ecotoxicológicas |
| dc.subject.proposal.spa.fl_str_mv |
Sensores fluorescentes Análogos de curcumina Quimiosensores Metales de transición |
| description |
La contaminación del agua es un problema serio para la salud y el medio ambiente, lo que hace crucial monitorear su calidad. Los métodos tradicionales como la espectroscopia de absorción atómica y la espectrometría de plasma son efectivos pero costosos y lentos. En respuesta, se han desarrollado métodos fluorogénicos y cromogénicos que ofrecen una alternativa rápida y eficiente para detectar trazas de iones metálicos en solución. Estos sensores, en particular los que tienen propiedades de fluorescencia, son valorados por su especificidad y sensibilidad, siendo ideales para uso en áreas remotas. Este estudio avanza en el desarrollo de sensores ópticos fluorescentes, y describe la síntesis de nuevos compuestos tipo heptanoides β-dicarbonílicos, similares a la curcumina, pero más efectivos en detectar iones metálicos. Estos compuestos muestran propiedades fluorescentes al reaccionar con metales de transición, ofreciendo nuevas posibilidades para la detección de contaminantes. La caracterización de estos sensores se realiza mediante técnicas avanzadas como la espectroscopía infrarroja y la resonancia magnética nuclear, y se evalúa su eficacia y toxicidad mediante espectrofotometría ultravioleta-visible y pruebas ecotoxicológicas en bulbos de cebolla. |
| publishDate |
2024 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-08T18:38:15Z |
| dc.date.available.none.fl_str_mv |
2024-05-08T18:38:15Z |
| dc.date.issued.none.fl_str_mv |
2024-05-08 |
| dc.type.local.spa.fl_str_mv |
Trabajo de grado |
| dc.type.version.none.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
| dc.type.category.spa.fl_str_mv |
Formación de Recurso Humano para la Ctel: Trabajo de grado de Pregrado |
| dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_7a1f |
| dc.type.drive.none.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
| format |
http://purl.org/coar/resource_type/c_7a1f |
| status_str |
acceptedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Pinzón Troncoso, J.A. (2024). Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos. [Trabajo de pregrado]. Universidad Santo Tomás, Bucaramanga, Colombia |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/11634/55061 |
| dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional Universidad Santo Tomás |
| dc.identifier.instname.spa.fl_str_mv |
instname:Universidad Santo Tomás |
| dc.identifier.repourl.spa.fl_str_mv |
repourl:https://repository.usta.edu.co |
| identifier_str_mv |
Pinzón Troncoso, J.A. (2024). Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos. [Trabajo de pregrado]. Universidad Santo Tomás, Bucaramanga, Colombia reponame:Repositorio Institucional Universidad Santo Tomás instname:Universidad Santo Tomás repourl:https://repository.usta.edu.co |
| url |
http://hdl.handle.net/11634/55061 |
| dc.language.iso.spa.fl_str_mv |
spa |
| language |
spa |
| dc.relation.references.spa.fl_str_mv |
Abdulgader, A., Mohammed N, J., & Amenah M, A. (2021). Synthesis, characterization and molecular docking of new gold complexes as a breast anticancer. Materialstoday: proceedings. 45(6). 5635-5641. https://doi.org/10.1016/j.matpr.2021.02.383 Agrawal, N.; Jaiswal, M. (2022) Bioavailability enhancement of curcumin via esterification processes: A review. Eur. J. Med. Chem. Rep. 6 100081. https://doi.org/10.1016/j.ejmcr.2022.100081 Ahmed, S., Shaikh, N., Pathak, N., Sonawane, A., Pandey, V., Maratkar, S. (2019). Tools, Techniques and Protocols for Monitoring Environmental Contaminants. Chapter 3 An overview of sensitivity and selectivity of biosensors for environmental applications, 53-73. ISBN 978-0-12-814679-8 https://doi.org/10.1016/B978-0-12-814679-8.00003-0 Al-Noor, T.; Ali, A.; Al-Sarray, A.; Al-Obaidi, O.; Obeidat, A.; Habash, R. (2022). A Short Review: Chemistry of Curcumin and Its Metal Complex Derivatives. J. Univ. Anbar Pure Sci. 16. 20–26. https://doi.org/10.37652/juaps.2022.174832 Ashoka, A-H., Aparin, I-O., Reischa, A., Klymchenko, A-S. (2023) Brightness of fluorescent organic nanomaterials. Chemical Society Reviews. 52, 4525-4548. https://doi.org/10.1039/D2CS00464J Baby, R., Saifullah, B. & Hussein, M.Z. (2019). Carbon Nanomaterials for the Treatment of Heavy Metal-Contaminated Water and Environmental Remediation. Nanoscale Res Lett 14. 341. https://doi.org/10.1186/s11671-019-3167-8 Bansod, B.K.; Kumar, T.; Thakur, R.; Rana, S.; Singh, I. (2017). A review on various electrochemical techniques for heavy metal ions detection with different sensing platforms. Biosens. Bioelectron. 94, 443–455. https://doi.org/10.1016/j.bios.2017.03.031 Charkiewicz, A-E., Omeljaniuk, W-J., Nowak, K., Garley, M., Nikliński, J. (2023). Cadmium Toxicity and Health Effects—A Brief Summary. Molecules. 28(18). 6620. https://doi.org/10.3390/molecules28186620 Chanajaree, R.; Ratanatawanate, C.; Ruangchaithaweesuk, S.; Lee, V.S.; Wittayanarakul, K. (2021). Colorimetric Detection of Pb2+ Ions Using Curcumin Silver Nanoparticles. Journal of Molecular Liquids. 343, 117629. https://doi.org/10.1016/j.molliq.2021.117629 Chaudhry, H., Rangra, N.K. (2023). Development and validation of a stability indicating green analytical method for the simultaneous estimation of L-glutathione, N-acetyl L-cysteine and Vitamin C in marketed formulation using UV–visible spectroscopy. Future Journal of Pharmaceutical Sciences. 9(74). 1-18. https://doi.org/10.1186/s43094-023-00523-y Chirayil C. J., Abraham J., Mishra R. K., George S. C., Thomas S. (2017). Thermal and Rheological Measurement Techniques for Nanomaterials Characterization Micro and Nano Technologies Chapter 1-instrumental techniques for the characterization of nanoparticles. 1-36. https://doi.org/10.1016/B978-0-323-46139-9.00001-3 Ciuca, M.D.; Racovita, R.C. (2023). Curcumin: Overview of Extraction Methods, Health Benefits, and Encapsulation and Delivery Using Microemulsions and Nanoemulsions. Int. J. Mol. Sci. 24. 8874. https://doi.org/10.3390/ijms24108874 De Acha. N., Elosúa. C., Corres. J.M., Arregui. F.J. (2019). Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media. Sensors. 19(3), 599. https://doi.org/10.3390/s19030599 Devasena, T., Balasubramanian, N., Muninathan, N., Baskaran, K., & John, S. (2022). Review Article: Curcumin Is an Iconic Ligand for Detecting Environmental Pollutants. Bioinorganic Chemistry and Applications. Hindawi Bioinorganic Chemistry and Applications. 9248988. 1-12. https://doi.org/10.1155/2022/9248988 Dong, J., Zhao, D., Lu, Y., Sun, W.-Y. (2019). J. Mater. Chem. A. 7. 22744-22767. https://doi.org/10.1039/C9TA07022B El Espectador. (11 de Agosto de 2022). Han aumentado los niveles de mercurio en el río Suratá, en Santander. El Espectador. https://www.elespectador.com/colombia/mas-regiones/han-aumentado-los-niveles-de-mercurio-en-el-rio-surata-en-santander/ El-Menyawy, E.M.; Raslan, M.; Zedan, I.T. Physical characteristics of naturally isolated high-purity curcumin and its application in photosensor appliances. J. Mol. Struct. 1274. 134445. https://doi.org/10.1016/j.molstruc.2022.134445 Ensayo de toxicidad aguda con Allium cepa L mediante la evaluación de la inhibición del crecimiento promedio de raíces de cebolla. (2004). En G. C. Morales, Ensayos toxicológicos y métodos de evaluación de calidad de aguas. Estandarización, intercalibración, resultados y aplicaciones (págs. 47-52). México: Instituto Mexicano de Tecnologia del Agua . Fakayode, S-O., Lisse, C., Medawala, W., Brady, P-N., Bwambok, D-K., Anum, D., Alonge, T., Taylor, M-E., Baker, G-A., Mehari, T-F., Rodriguez,J.D., Elzey, B., Siraj, N., Macchi, S., Le, T., Forson, M., Bashiru, M., Fernand.N, V.E., Grant, C. (2023). Fluorescent chemical sensors: applications in analytical, environmental, forensic, pharmaceutical, biological, and biomedical sample measurement, and clinical diagnosis, Applied Spectroscopy Reviews, 1-89. https://doi.org/10.1080/05704928.2023.2177666 Fonnegra, M. I. (05 de Febrero de 2023). Alerta por alta presencia de mercurio en importante río de Santander . El Tiempo. https://www.eltiempo.com/justicia/investigacion/mercurio-en-rio-de-santnder-prende-alertas-de-autoridades-739429 Hajare,S.T., Kadam,G.L., Charde, S., Chakole, D., Bhor. A. (2023). Spectrofluorimetry At A Glance: A Review. International Journal of Creative Research Thoughts (IJCRT). 11(6). 337-349. https://ijcrt.org/papers/IJCRT2306255.pdf Heidari, Z., Daei, M., Boozari, M., Jamialahmadi, T., & Sahebkar, A. (2022). Curcumin supplementation in pediatric patients: A systematic review of current clinical evidence. Phytotherapy Research, 36(4), 1442–1458. https://doi.org/10.1002/ptr.7350 Jun, J-V., Chenoweth, D-M., Petersson, E-J. (2020). Rational design of small molecule fluorescent probes for biological Applications. Org. Biomol. Chem. 30(18). 5747-5763. https://doi.org/10.1039/D0OB01131B Kaplaneris, N., Ackermann. L. (2022). Earth-abundant 3d transition metals on the rise in catalysis. Beilstein J. Org. Chem., 18, 86–88. https://doi.org/10.3762/bjoc.18.8 Kharat, M.; Du, Z.; Zhang, G.; Mc Clements, D.J. (2017) Physical and Chemical Stability of Curcumin in Aqueous Solutions and Emulsions: Impact of PH, Temperature, and Molecular Environment. Journal of Agricultural and Food Chemistry. 65 (8). 1525–1532. https://doi.org/10.1021/acs.jafc.6b04815 Keith, S. (2020). Turmeric: Potential Health Benefits. Nutrition Today 55(1). 45-46. https://journals.lww.com/nutritiontodayonline/fulltext/2020/01000/turmeric__potential_health_benefits.9.aspx Ko-Hsiu Lu, K-H., Wun-Ang Lu, P., Wun-Hao Lu, E., Lin, CH-W., Yang, S-F. (2023). Curcumin and its Analogs and Carriers: Potential Therapeutic Strategies for Human Osteosarcoma. Int J Biol Sci. 19(4). 1241-1265. https://www.ijbs.com/v19p1241.htm Kotha, R.R.; Luthria, D.L. (2019). Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects. Molecules. 24. 2930. https://doi.org/10.3390/molecules24162930 Kościelniak, P. (2022). Calibration methods in qualitative analysis. TrAC Trends in Analytical Chemistry. 150. 116587. https://doi.org/10.1016/j.trac.2022.116587 Kirschning, A. (2022). On the Evolutionary History of the Twenty Encoded Amino Acids. Chemistry A European Journal. 28(55), 1419; https://doi.org/10.1002/chem.202201419 Kulkarni, P., Kondhare, D., Varala, R., & Zubaidha, P. (2013). Calcium Hydroxide: An efficient and mild base for one-pot synthesis of curcumin and it´s analogues. Acta Chimica Slovaca 6(1). 150-156. https://doi.org/10.2478/acs-2013-0023 Levine, M. (2021). Fluorescence-Based Sensing of Pesticides Using Supramolecular Chemistry Frontiers in Chemistry. 9. 616815. https://doi.org/10.3389/fchem.2021.616815 Liang, S-T., Chen, Ch., Chen, R-X., Li, R., Chen, W-L., Jiang, G-H., Du, L-L. (2022). Michael acceptor molecules in natural products and their mechanism of action. Frontiers in Pharmacology. 13. 1-17. https://doi.org/10.3389/fphar.2022.1033003. Li, Y., Young, D-J., Loh, X-J. (2019). Mater. Chem. Front. 20(3). 1489-1502. https://doi.org/10.1039/C9QM00127A Li, Z., Liang, P-Z., Ren, T-B.,Yuan, L., Zhang, X-B. (2023). Orderly Self-Assembly of Organic Fluorophores for Sensing and Imaging. 62(37), 5742. https://onlinelibrary.wiley.com/doi/10.1002/anie.202305742 Lin, Y., Yu, A., Wang, J., Kong, D., Liu, H., Li, J., Ch, J. (2022). A curcumin-based AIEE-active fluorescent probe for Cu2+ detection in aqueous solution. RSC, Adv. 12, 16772-16778. https://doi.org/10.1039/D2RA02595G Liu, B., Zhuang, L., Wei, G. (2020). Recent advances in the design of colorimetric sensors for environmental monitoring, Environ. Sci, Nano. 7(8), 2195–2213. https://doi.org/10.1039/D0EN00449A Londoño Franco, L. F., Londoño Muñoz, P. T., & Muñoz García, F. G. (Diciembre de 2016). Los riesgos de los metales pesados en la salud humana y animal. Obtenido de Biotecnología en el sector agropecuario y agroindustrial: http://dx.doi.org/10.18684/BSAA(14)145-153 Lu, K.-H., Lu, P.-W.-A., Lu, E.-W.-H., Lin, C.-W., & Yang, S.-F. (2023). Curcumin and its analogs and carriers: Potential therapeutic strategies for human osteosarcoma. International Journal of Biological Sciences, 19(4), 1241. https://www.ijbs.com/v19p1241.htm Mary, C.P.V., Vijayakumar, S., Shankar, R. (2018). Metal chelating ability and antioxidant properties of curcumin‐metal complexes–A DFT approach. J. Mol. Gr. Modell. 79. 1–14. https://doi.org/10.1016/j.jmgm.2017.10.022. Mondal, S.; Ghosh, S.; Moulik, S.P. (2016). Stability of curcumin in different solvent and solution media: UV-visible and steady-state fluorescence spectral study. J. Photochem. Photobiol. B. 158. 212–218. https://doi.org/10.1016/j.jphotobiol.2016.03.004 Moosavi, M.S., Ghassabian, S. (2018). Calibration and Validation of Analytical Methods - A Sampling of Current Approaches (Edited by Mark Stauffer). Chapter 6 Linearity of Calibration Curves for Analytical Methods: A Review of Criteria for Assessment of Method Reliability. IntechOpen, 1-174; ISBN 978-1-78923-085-7 https://www.intechopen.com/chapters/58596 Mostafiz, B., Bigdeli, S-A., Banan, K., Afsharara, H., Hatamabadi., D., Mousavi, P., Hussain, CH-M., Keçili, R., Ghorbani-Bidkorbeh., F. (2021). Molecularly imprinted polymer-carbon paste electrode (MIPCPE)-based sensors for the sensitive detection of organic and inorganic environmental pollutants: a review, Trends Environ. Anal. Chem. 32. e00144. https://doi.org/10.1016/j.teac.2021.e00144 Mulyaningsih, R.D., Pratiwi, R., Hasanah, A.N. (2023). An Update on the Use of Natural Pigments and Pigment Nanoparticle Adducts for Metal Detection Based on Colour Response. Biosensors. 13. 554. https://doi.org/10.3390/bios13050554. Múnera, M. (27 de noviembre de 2022). Por hallazgo de metales pesados en plantas, fundacion no usa matas de Santurbán. Obtenido de El Tiempo: https://www.eltiempo.com/colombia/santander/plantas-de-santurban-estan-contaminadas-con-metales-pesados-720870 Nilsson, J-R., Benitez-Martin, C., Sansom, H-G., Pfeiffer, P., Baladi,T., Le, H-N., Dahlén, A., Magennis, S-W., Wilhelmsson, L-M. (2023). Phys. Chem. Chem. Phys. 25. 20218–20224. https://doi.org/10.1039/D3CP01147J Noureddin, S-A., El-Shishtawy, R., Al-Footy, K-O. (2023). Curcumin analogues and their hybrid molecules as multifunctional drugs. European Journal of Medicinal Chemistry.182. 111631. https://doi.org/10.1016/j.ejmech.2019.111631 Omach, Z.; Odhiambo, B.; Owoko, W. (2023). Health Impacts of Mercury Toxicity on Fish in an Aquatic System. Preprints. 2023081908. https://doi.org/10.20944/preprints202308.1908.v1 Orteca, G.; Sinnes, J.P.; Piel, M.; Roesch, F.; Ferrari, E.; Asti, M.; Rubagotti, S.; Bednarikova, Z.; Capponi, Z.; Pier, C. (2019). P#115 - 68Ga-Curcumin-Based Bifunctional Ligands for Alzheimer’s Disease Diagnosis. Nuclear Medicine and Biology. 72–73(1). S43–S44. https://doi.org/10.1016/S0969-8051(19)30308-7. Pabón, S., Benítez, R., Sarria, R.A., Gallo, J. (2020). Contaminación del agua por metales pesados, métodos de análisis y tecnologías de remoción. Una revisión. Entre Ciencia e Ingeniería. 14(27). 9-18. http://www.scielo.org.co/pdf/ecei/v14n27/1909-8367-ecei-14-27-9.pdf Paden, R.R., Oracion, J.P.L., De La Rosa, L.B., Lavapiez, M.A.M., Alguno, A.C., Deocaris, D.C., Capangpangan, R.Y. (2021). Design and fabrication of a low-cost curcumin-based paper sensor for rapid ‘‘naked-eye” cyanide sensing. Materials Today: Proceedings. 46(4). 1711-1717. https://doi.org/10.1016/j.matpr.2020.07.374 Phatthanawiwat, K.; Boonkanon, C.; Wongniramaikul, W.; Choodum, A. (2022). Catechin and Curcumin Nanoparticle-Immobilized Starch Cryogels as Green Colorimetric Sensors for on-Site Detection of Iron. Sustainable Chemistry and Pharmacy. 2022, 29, 100782. https://doi.org/10.1016/j.scp.2022.100782. Prasad, S.; DuBourdieu, D., Srivastava, A., Kumar, P., Lall, R. (2021). Metal–Curcumin Complexes in Therapeutics: An Approach to Enhance Pharmacological Effects of Curcumin. Int. J. Mol. Sci. 22. 7094. https://doi.org/10.3390/ijms22137094 Rai, M., Ingle, A. P., Pandit, R., Paralikar, P., Anasane, N., & Santos, C. A. D. (2020). Curcumin and curcumin-loaded nanoparticles: Antipathogenic and antiparasitic activities. Expert Review of Anti-infective Therapy, 18(4), 367–379. https://doi.org/10.1080/14787210.2020.1730815 Rainey, N.E., Moustapha, A., Saric, A., Nicolas, G., Sureau, F., Petit, P.X. (2019). Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation. Cell Death Discovery. 5(150). 2-15. https://doi.org/10.1038/s41420-019-0234-y Rathore, M.M.S.; Sharma, P.; Devi, S.; Nagar, J.C.; Khalid, M. (2020). Curcumin: A Review for Health Benefits. Int. J. Res. Rev. 7. 273–290. Rao, T.N. (2018). Chapter 7 Validation of Analytical Methods. Book: Calibration and Validation of Analytical Methods - A Sampling of Current Approaches. Edited by Mark Stauffer. ISBN 978-1-78923-085-7. https://www.intechopen.com/books/6379 Rodríguez, J. C. (2019). Síntesis y caracterización de análogos de curcumina y sus complejos metálicos de cobre. Ciudad de México: Universidad Nacional Autónoma de México. Sabzkoohi, H.A., Dodier, V., Kolliopoulos, G. (2023). A validated analytical method to measure metals dissolved in deep eutectic solvents. RSC Adv., 13, 14887. https://pubs.rsc.org/en/content/articlepdf/2023/ra/d3ra02372a Salem, M.A.; El-Shiekh, R.A.; Fernie, A.R.; Alseekh, S.; Zayed, A. (2022). Metabolomics-based profiling for quality assessment and revealing the impact of drying of Turmeric (Curcuma longa L.). Sci. Rep. 12. 10288. https://doi.org/10.3390/molecules27165055 Salehi-Babarsad, F., Derikvand, E., Razaz, M., Yousefi, R., Shirmardi, A. (2019). Heavy metal removal by using ZnO/organic and ZnO/ inorganic nanocomposite heterostructures, Int. J. Environ. Anal. Chem. 100(6). 702–719. https://doi.org/10.1080/03067319.2019.1639685 Sanchez Arenas, J. C., Tapia López, L., García Meza, M. G., & Ocaranza Sánchez, E. (2022). Compuestos Curcuminoides: Una Posible Solución Natural Para Tratar El Cáncer. Frontera Biotecnológica, 27-32. ISSN: 2448-8461 https://www.revistafronterabiotecnologica.cibatlaxcala.ipn.mx/volumen/vol22/pdf/vol-22-4.pdf Sani, A-H., Amanabo, M. (2021). Lead: A concise review of its toxicity, mechanism and health effect. GSC Biological and Pharmaceutical Sciences. 15(01). 055-062. https://doi.org/10.30574/gscbps.2021.15.1.0096 Saranya, J., Sreeja, B.S., Padmalaya, G., Fadha, S., Arivanandan, M. (2021). Microwave thermally assisted porous structured cerium oxide/zinc oxide design: fabrication, electrochemical activity towards Pb ions, anticancer assessment in HeLa and VERO cell lines, J. Organ. Organometall. Polym. Mater. 31, 1279–1292. https://link.springer.com/article/10.1007/s10904-020-01809-x Servicios técnicos de investigación. (2 de Febrero de 2023). Universidad de Alicante. Obtenido de Espectroscopía ultravioleta visible: https://sstti.ua.es/es/instrumentacion-cientifica/unidad-de-rayos-x-de-monocristal-y-espectroscopias-vibracional-y-optica/espectroscopia-ultravioleta-visible.html Shakoor, S., Ismail, A., Sabran, M. R., Mohtarrudin, N., Kaka, U., & Nadeem, M. (2021). In-vivo study of synthetic and natural food colors effect on biochemical and immunity parameters. Food Science and Technology, 42, e41420. https://doi.org/10.1590/fst.41420 Sharifi-Rad, J., El Rayess, Y., Abi Rizk, A., Sadaka, C., Zgheib, R., Zam, W., Martins, N. (2020). Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and MEdicinal Applications. Frontiers in Pharmacology. 11. 1-23. https://doi.org/10.3389/fphar.2020.01021 Sheikhzadeh, E.; Naji-Tabasi, S.; Verdian, A.; Kolahi-Ahari, S. (2022). Equipment-Free and Visual Detection of Pb2+ Ion Based on Curcumin-Modified Bacterial Cellulose Nanofiber. Journal of the Iranian Chemical Society. 19, 283–290. https://doi.org/10.1007/s13738-021-02305-w Shin, D.Y.; Lee, S.M.; Jang, Y.; Lee, J.; Lee, C.M.; Cho, E.-M.; Seo, Y.R. (2023). Adverse Human Health Effects of Chromium by Exposure Route: A Comprehensive Review Based on Toxicogenomic Approach. Int. J. Mol. Sci. 24. 3410. https://doi.org/10.3390/ijms24043410 Shinozaki, Y., Popov, S., Plenio, H. (2023). Fluorescent organometallic dyads and triads: establishing spatial relationships. Chemical Science. 14. 350-361. https://doi.org/10.1039/D2SC04869H Suhito, I. R., Lee, W., Baek, S., Lee, D., Min, J., & Kim, T.-H. (2019). Rapid and sensitive electrochemical detection of anticancer effects of curcumin on human glioblastoma cells. Sensors and Actuators B: Chemical. 288. 527–534. https://doi.org/10.1016/j.snb.2019.03.031 Tabanelli, R.; Brogi, S.; Calderone, V. (2021). Improving Curcumin Bioavailability: Current Strategies and Future Perspectives. Pharmaceutics. 13(10). 1715. https://doi.org/10.3390/pharmaceutics13101715 Trivedi, P., & Axe, L. (2000). Modeling Cd and Zn sorption to hydrous metal oxides. Environ. Sci. Technol. 34(11). 2215–2223. https://doi.org/10.1021/es991110c Tsuda, T. (2018). Curcumin as a functional food-derived factor: Degradation products, metabolites, bioactivity, and future perspectives. Food Funct. 9. 705–714. https://doi.org/10.1039/C7FO01242J Vonnie, J.M.; Ting, B.J.; Rovina, K.; Erna, K.H.; Felicia,W.X.L.; ‘Aqilah, N.M.N.;Wahab, R.A.(2022). Development of Aloe Vera-Green Banana Saba-Curcumin Composite Film for Colorimetric Detection of Ferrum (II). Polymers. 14(12). 2353. https://doi.org/10.3390/polym14122353 Wang, B., Wang, L., Chen, Ch., Zhang, Y., Gao, J., Lu, K., Yan,Ch., Nan, G., Li, Y. (2023). A Review on Recent Advances in Peptide-based Fluorescence Probes and their Potential Applications. 8(31). e202302216. https://doi.org/10.1002/slct.202302216 Wang, Y., Wang, J-K., Alkhazragi, O., Gutiérrez-Arzaluz, L., Zhang, H., Kang, Ch-H., Khee Ng, T., Bakr, O.M., Mohammed, O.F., Ooi, B.S. (2023). Multifunctional difluoroboron β-diketonate-based luminescent receiver for a high-speed underwater wireless optical communication system. Optics Express. 31(20). 32516-32528. https://doi.org/10.1364/OE.500330 Waure, Ch., Bertola, C., Baccarini, G., Chiavarini, M., Mancuso, C. (2023). Exploring the Contribution of Curcumin to Cancer Therapy: A Systematic Review of Randomized Controlled Trials. Pharmaceutics. 15(4). 1275. https://doi.org/10.3390/pharmaceutics15041275 Xiaa, J., Xiongb, Y., Minb, S., Li, J. (2022). A review of recent infrared spectroscopy research for paper. Applied Spectroscopy Reviews. https://doi.org/10.1080/05704928.2022.2142939 Xie R., Su D., Song Y., Sun P., Mao B., Tian M., Chai F. (2023). The synthesis of gold nanoclusters with high stability and their application in fluorometric detection for Hg2+ and cell imaging. Talanta. 260. 124573. https://doi.org/10.1016/j.talanta.2023.124573 Xu, H., Zhang, W., Wang, M. (2022). Bioinspired Fluorescent Polymers: Synthesis, Processing, and Applications. Chinese Journal of Chemistry. 41(4). 458-468. https://doi.org/10.1002/cjoc.202200493 Yang, D., Liu, Y., Geng, J., Kou, X., Xin, Z., Lv, M. (2018). Engineering nanomaterials-based biosensors for food safety detection. Biosens. Bioelectron. 106, 122–128. https://doi.org/10.1016/j.bios.2018.01.049 Zacharioudaki, D-E., Fitilis, I., Kotti, M. (2022). Review of Fluorescence Spectroscopy in Environmental Quality Applications. Molecules, 27(15), 4801. https://doi.org/10.3390/molecules27154801 Zainab, A., Rooh Ullah, M., Tuzen, S-U., Rahim, A., Tawfik, A-S.. (2023). Colorimetric sensing of heavy metals on metal doped metal oxide nanocomposites: A review, Trends in Environmental Analytical Chemistry. 37. e00187. https://doi.org/10.1016/j.teac.2022.e00187. Zhang, Y., Khan, A.R., Fu, M., Zhai, Y., Yu, A., Zha, G. (2019) The progresses in curcuminoids-based metal complexes: especially in cancer therapy. Future Medicinal Chemistry. 11(9). 1035–1056. https://doi.org/10.4155/fmc-2018-0190. |
| dc.rights.*.fl_str_mv |
Atribución-NoComercial-SinDerivadas 2.5 Colombia |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/2.5/co/ |
| dc.rights.local.spa.fl_str_mv |
Abierto (Texto Completo) |
| dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| rights_invalid_str_mv |
Atribución-NoComercial-SinDerivadas 2.5 Colombia http://creativecommons.org/licenses/by-nc-nd/2.5/co/ Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.coverage.campus.spa.fl_str_mv |
CRAI-USTA Bucaramanga |
| dc.publisher.spa.fl_str_mv |
Universidad Santo Tomás |
| dc.publisher.program.spa.fl_str_mv |
Pregrado Química Ambiental |
| dc.publisher.faculty.spa.fl_str_mv |
Facultad de Química Ambiental |
| institution |
Universidad Santo Tomás |
| bitstream.url.fl_str_mv |
https://repository.usta.edu.co/bitstream/11634/55061/6/2024Pinz%c3%b3nJennifer.pdf.jpg https://repository.usta.edu.co/bitstream/11634/55061/7/2024Pinz%c3%b3nJennifer1.pdf.jpg https://repository.usta.edu.co/bitstream/11634/55061/8/2024Pinz%c3%b3nJennifer2.pdf.jpg https://repository.usta.edu.co/bitstream/11634/55061/5/license.txt https://repository.usta.edu.co/bitstream/11634/55061/1/2024Pinz%c3%b3nJennifer.pdf https://repository.usta.edu.co/bitstream/11634/55061/2/2024Pinz%c3%b3nJennifer1.pdf https://repository.usta.edu.co/bitstream/11634/55061/3/2024Pinz%c3%b3nJennifer2.pdf https://repository.usta.edu.co/bitstream/11634/55061/4/license_rdf |
| bitstream.checksum.fl_str_mv |
46a650f05d79dec9da7b12cd2eeb4a87 6a232a85ada18c3233c20a665d312518 e33fd699f747fb9bf41c5b1ff1e371cb aedeaf396fcd827b537c73d23464fc27 4094f5d3a177fff29c38626be1c85b62 9188c58fba1b643ae201b5fcdb57f962 65854aaf6f007025cac067d996c257b0 217700a34da79ed616c2feb68d4c5e06 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Universidad Santo Tomás |
| repository.mail.fl_str_mv |
noreply@usta.edu.co |
| _version_ |
1860882180598661120 |
| spelling |
Osorio Martínez, Carlos AlbertoPinzón Troncoso, Jennifer Alejandra2024-05-08T18:38:15Z2024-05-08T18:38:15Z2024-05-08Pinzón Troncoso, J.A. (2024). Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-Aminoácidos. [Trabajo de pregrado]. Universidad Santo Tomás, Bucaramanga, Colombiahttp://hdl.handle.net/11634/55061reponame:Repositorio Institucional Universidad Santo Tomásinstname:Universidad Santo Tomásrepourl:https://repository.usta.edu.coLa contaminación del agua es un problema serio para la salud y el medio ambiente, lo que hace crucial monitorear su calidad. Los métodos tradicionales como la espectroscopia de absorción atómica y la espectrometría de plasma son efectivos pero costosos y lentos. En respuesta, se han desarrollado métodos fluorogénicos y cromogénicos que ofrecen una alternativa rápida y eficiente para detectar trazas de iones metálicos en solución. Estos sensores, en particular los que tienen propiedades de fluorescencia, son valorados por su especificidad y sensibilidad, siendo ideales para uso en áreas remotas. Este estudio avanza en el desarrollo de sensores ópticos fluorescentes, y describe la síntesis de nuevos compuestos tipo heptanoides β-dicarbonílicos, similares a la curcumina, pero más efectivos en detectar iones metálicos. Estos compuestos muestran propiedades fluorescentes al reaccionar con metales de transición, ofreciendo nuevas posibilidades para la detección de contaminantes. La caracterización de estos sensores se realiza mediante técnicas avanzadas como la espectroscopía infrarroja y la resonancia magnética nuclear, y se evalúa su eficacia y toxicidad mediante espectrofotometría ultravioleta-visible y pruebas ecotoxicológicas en bulbos de cebolla.Water pollution is a serious issue for human health and the environment, making it crucial to monitor water quality. Traditional methods such as atomic absorption spectroscopy and plasma spectrometry are effective but costly and slow. In response, fluorogenic and chromogenic methods have been developed, offering a rapid and efficient alternative for detecting traces of metal ions in solution. These sensors, particularly those with fluorescence properties, are valued for their specificity and sensitivity, making them ideal for use in remote areas. This study advances the development of fluorescent optical sensors and describes the synthesis of new heptanoid β-diketone compounds, like curcumin but more effective in detecting metal ions. These compounds exhibit fluorescent properties when reacting with transition metals, offering new possibilities for pollutant detection. The characterization of these sensors is carried out using advanced techniques such as infrared spectroscopy and nuclear magnetic resonance, and their efficacy and toxicity are assessed through ultraviolet-visible spectrophotometry and ecotoxicological tests on onion bulbs.Químico Ambientalhttps://www.ustabuca.edu.co/Pregradoapplication/pdfspaUniversidad Santo TomásPregrado Química AmbientalFacultad de Química AmbientalAtribución-NoComercial-SinDerivadas 2.5 Colombiahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/Abierto (Texto Completo)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Síntesis De Sensores Para Detección De Iones Metálicos En Solución Basados En Análogos De Curcumina-AminoácidosFluorescent sensorsChemosensorsCurcumin analogsTransition metalsEspectrometríaDetección de contaminantesEspectroscopia InfrarrojaEspectrofotometría de ultravioleta visiblePruebas ecotoxicológicasSensores fluorescentesAnálogos de curcuminaQuimiosensoresMetales de transiciónTrabajo de gradoinfo:eu-repo/semantics/acceptedVersionFormación de Recurso Humano para la Ctel: Trabajo de grado de Pregradohttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesisCRAI-USTA BucaramangaAbdulgader, A., Mohammed N, J., & Amenah M, A. (2021). Synthesis, characterization and molecular docking of new gold complexes as a breast anticancer. Materialstoday: proceedings. 45(6). 5635-5641. https://doi.org/10.1016/j.matpr.2021.02.383Agrawal, N.; Jaiswal, M. (2022) Bioavailability enhancement of curcumin via esterification processes: A review. Eur. J. Med. Chem. Rep. 6 100081. https://doi.org/10.1016/j.ejmcr.2022.100081Ahmed, S., Shaikh, N., Pathak, N., Sonawane, A., Pandey, V., Maratkar, S. (2019). Tools, Techniques and Protocols for Monitoring Environmental Contaminants. Chapter 3 An overview of sensitivity and selectivity of biosensors for environmental applications, 53-73. ISBN 978-0-12-814679-8 https://doi.org/10.1016/B978-0-12-814679-8.00003-0Al-Noor, T.; Ali, A.; Al-Sarray, A.; Al-Obaidi, O.; Obeidat, A.; Habash, R. (2022). A Short Review: Chemistry of Curcumin and Its Metal Complex Derivatives. J. Univ. Anbar Pure Sci. 16. 20–26. https://doi.org/10.37652/juaps.2022.174832Ashoka, A-H., Aparin, I-O., Reischa, A., Klymchenko, A-S. (2023) Brightness of fluorescent organic nanomaterials. Chemical Society Reviews. 52, 4525-4548. https://doi.org/10.1039/D2CS00464JBaby, R., Saifullah, B. & Hussein, M.Z. (2019). Carbon Nanomaterials for the Treatment of Heavy Metal-Contaminated Water and Environmental Remediation. Nanoscale Res Lett 14. 341. https://doi.org/10.1186/s11671-019-3167-8Bansod, B.K.; Kumar, T.; Thakur, R.; Rana, S.; Singh, I. (2017). A review on various electrochemical techniques for heavy metal ions detection with different sensing platforms. Biosens. Bioelectron. 94, 443–455. https://doi.org/10.1016/j.bios.2017.03.031Charkiewicz, A-E., Omeljaniuk, W-J., Nowak, K., Garley, M., Nikliński, J. (2023). Cadmium Toxicity and Health Effects—A Brief Summary. Molecules. 28(18). 6620. https://doi.org/10.3390/molecules28186620Chanajaree, R.; Ratanatawanate, C.; Ruangchaithaweesuk, S.; Lee, V.S.; Wittayanarakul, K. (2021). Colorimetric Detection of Pb2+ Ions Using Curcumin Silver Nanoparticles. Journal of Molecular Liquids. 343, 117629. https://doi.org/10.1016/j.molliq.2021.117629Chaudhry, H., Rangra, N.K. (2023). Development and validation of a stability indicating green analytical method for the simultaneous estimation of L-glutathione, N-acetyl L-cysteine and Vitamin C in marketed formulation using UV–visible spectroscopy. Future Journal of Pharmaceutical Sciences. 9(74). 1-18. https://doi.org/10.1186/s43094-023-00523-yChirayil C. J., Abraham J., Mishra R. K., George S. C., Thomas S. (2017). Thermal and Rheological Measurement Techniques for Nanomaterials Characterization Micro and Nano Technologies Chapter 1-instrumental techniques for the characterization of nanoparticles. 1-36. https://doi.org/10.1016/B978-0-323-46139-9.00001-3Ciuca, M.D.; Racovita, R.C. (2023). Curcumin: Overview of Extraction Methods, Health Benefits, and Encapsulation and Delivery Using Microemulsions and Nanoemulsions. Int. J. Mol. Sci. 24. 8874. https://doi.org/10.3390/ijms24108874De Acha. N., Elosúa. C., Corres. J.M., Arregui. F.J. (2019). Fluorescent Sensors for the Detection of Heavy Metal Ions in Aqueous Media. Sensors. 19(3), 599. https://doi.org/10.3390/s19030599Devasena, T., Balasubramanian, N., Muninathan, N., Baskaran, K., & John, S. (2022). Review Article: Curcumin Is an Iconic Ligand for Detecting Environmental Pollutants. Bioinorganic Chemistry and Applications. Hindawi Bioinorganic Chemistry and Applications. 9248988. 1-12. https://doi.org/10.1155/2022/9248988Dong, J., Zhao, D., Lu, Y., Sun, W.-Y. (2019). J. Mater. Chem. A. 7. 22744-22767. https://doi.org/10.1039/C9TA07022BEl Espectador. (11 de Agosto de 2022). Han aumentado los niveles de mercurio en el río Suratá, en Santander. El Espectador. https://www.elespectador.com/colombia/mas-regiones/han-aumentado-los-niveles-de-mercurio-en-el-rio-surata-en-santander/El-Menyawy, E.M.; Raslan, M.; Zedan, I.T. Physical characteristics of naturally isolated high-purity curcumin and its application in photosensor appliances. J. Mol. Struct. 1274. 134445. https://doi.org/10.1016/j.molstruc.2022.134445Ensayo de toxicidad aguda con Allium cepa L mediante la evaluación de la inhibición del crecimiento promedio de raíces de cebolla. (2004). En G. C. Morales, Ensayos toxicológicos y métodos de evaluación de calidad de aguas. Estandarización, intercalibración, resultados y aplicaciones (págs. 47-52). México: Instituto Mexicano de Tecnologia del Agua .Fakayode, S-O., Lisse, C., Medawala, W., Brady, P-N., Bwambok, D-K., Anum, D., Alonge, T., Taylor, M-E., Baker, G-A., Mehari, T-F., Rodriguez,J.D., Elzey, B., Siraj, N., Macchi, S., Le, T., Forson, M., Bashiru, M., Fernand.N, V.E., Grant, C. (2023). Fluorescent chemical sensors: applications in analytical, environmental, forensic, pharmaceutical, biological, and biomedical sample measurement, and clinical diagnosis, Applied Spectroscopy Reviews, 1-89. https://doi.org/10.1080/05704928.2023.2177666Fonnegra, M. I. (05 de Febrero de 2023). Alerta por alta presencia de mercurio en importante río de Santander . El Tiempo. https://www.eltiempo.com/justicia/investigacion/mercurio-en-rio-de-santnder-prende-alertas-de-autoridades-739429Hajare,S.T., Kadam,G.L., Charde, S., Chakole, D., Bhor. A. (2023). Spectrofluorimetry At A Glance: A Review. International Journal of Creative Research Thoughts (IJCRT). 11(6). 337-349. https://ijcrt.org/papers/IJCRT2306255.pdfHeidari, Z., Daei, M., Boozari, M., Jamialahmadi, T., & Sahebkar, A. (2022). Curcumin supplementation in pediatric patients: A systematic review of current clinical evidence. Phytotherapy Research, 36(4), 1442–1458. https://doi.org/10.1002/ptr.7350Jun, J-V., Chenoweth, D-M., Petersson, E-J. (2020). Rational design of small molecule fluorescent probes for biological Applications. Org. Biomol. Chem. 30(18). 5747-5763. https://doi.org/10.1039/D0OB01131BKaplaneris, N., Ackermann. L. (2022). Earth-abundant 3d transition metals on the rise in catalysis. Beilstein J. Org. Chem., 18, 86–88. https://doi.org/10.3762/bjoc.18.8Kharat, M.; Du, Z.; Zhang, G.; Mc Clements, D.J. (2017) Physical and Chemical Stability of Curcumin in Aqueous Solutions and Emulsions: Impact of PH, Temperature, and Molecular Environment. Journal of Agricultural and Food Chemistry. 65 (8). 1525–1532. https://doi.org/10.1021/acs.jafc.6b04815Keith, S. (2020). Turmeric: Potential Health Benefits. Nutrition Today 55(1). 45-46. https://journals.lww.com/nutritiontodayonline/fulltext/2020/01000/turmeric__potential_health_benefits.9.aspxKo-Hsiu Lu, K-H., Wun-Ang Lu, P., Wun-Hao Lu, E., Lin, CH-W., Yang, S-F. (2023). Curcumin and its Analogs and Carriers: Potential Therapeutic Strategies for Human Osteosarcoma. Int J Biol Sci. 19(4). 1241-1265. https://www.ijbs.com/v19p1241.htmKotha, R.R.; Luthria, D.L. (2019). Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects. Molecules. 24. 2930. https://doi.org/10.3390/molecules24162930Kościelniak, P. (2022). Calibration methods in qualitative analysis. TrAC Trends in Analytical Chemistry. 150. 116587. https://doi.org/10.1016/j.trac.2022.116587Kirschning, A. (2022). On the Evolutionary History of the Twenty Encoded Amino Acids. Chemistry A European Journal. 28(55), 1419; https://doi.org/10.1002/chem.202201419Kulkarni, P., Kondhare, D., Varala, R., & Zubaidha, P. (2013). Calcium Hydroxide: An efficient and mild base for one-pot synthesis of curcumin and it´s analogues. Acta Chimica Slovaca 6(1). 150-156. https://doi.org/10.2478/acs-2013-0023Levine, M. (2021). Fluorescence-Based Sensing of Pesticides Using Supramolecular Chemistry Frontiers in Chemistry. 9. 616815. https://doi.org/10.3389/fchem.2021.616815Liang, S-T., Chen, Ch., Chen, R-X., Li, R., Chen, W-L., Jiang, G-H., Du, L-L. (2022). Michael acceptor molecules in natural products and their mechanism of action. Frontiers in Pharmacology. 13. 1-17. https://doi.org/10.3389/fphar.2022.1033003.Li, Y., Young, D-J., Loh, X-J. (2019). Mater. Chem. Front. 20(3). 1489-1502. https://doi.org/10.1039/C9QM00127ALi, Z., Liang, P-Z., Ren, T-B.,Yuan, L., Zhang, X-B. (2023). Orderly Self-Assembly of Organic Fluorophores for Sensing and Imaging. 62(37), 5742. https://onlinelibrary.wiley.com/doi/10.1002/anie.202305742Lin, Y., Yu, A., Wang, J., Kong, D., Liu, H., Li, J., Ch, J. (2022). A curcumin-based AIEE-active fluorescent probe for Cu2+ detection in aqueous solution. RSC, Adv. 12, 16772-16778. https://doi.org/10.1039/D2RA02595GLiu, B., Zhuang, L., Wei, G. (2020). Recent advances in the design of colorimetric sensors for environmental monitoring, Environ. Sci, Nano. 7(8), 2195–2213. https://doi.org/10.1039/D0EN00449ALondoño Franco, L. F., Londoño Muñoz, P. T., & Muñoz García, F. G. (Diciembre de 2016). Los riesgos de los metales pesados en la salud humana y animal. Obtenido de Biotecnología en el sector agropecuario y agroindustrial: http://dx.doi.org/10.18684/BSAA(14)145-153Lu, K.-H., Lu, P.-W.-A., Lu, E.-W.-H., Lin, C.-W., & Yang, S.-F. (2023). Curcumin and its analogs and carriers: Potential therapeutic strategies for human osteosarcoma. International Journal of Biological Sciences, 19(4), 1241. https://www.ijbs.com/v19p1241.htmMary, C.P.V., Vijayakumar, S., Shankar, R. (2018). Metal chelating ability and antioxidant properties of curcumin‐metal complexes–A DFT approach. J. Mol. Gr. Modell. 79. 1–14. https://doi.org/10.1016/j.jmgm.2017.10.022.Mondal, S.; Ghosh, S.; Moulik, S.P. (2016). Stability of curcumin in different solvent and solution media: UV-visible and steady-state fluorescence spectral study. J. Photochem. Photobiol. B. 158. 212–218. https://doi.org/10.1016/j.jphotobiol.2016.03.004Moosavi, M.S., Ghassabian, S. (2018). Calibration and Validation of Analytical Methods - A Sampling of Current Approaches (Edited by Mark Stauffer). Chapter 6 Linearity of Calibration Curves for Analytical Methods: A Review of Criteria for Assessment of Method Reliability. IntechOpen, 1-174; ISBN 978-1-78923-085-7 https://www.intechopen.com/chapters/58596Mostafiz, B., Bigdeli, S-A., Banan, K., Afsharara, H., Hatamabadi., D., Mousavi, P., Hussain, CH-M., Keçili, R., Ghorbani-Bidkorbeh., F. (2021). Molecularly imprinted polymer-carbon paste electrode (MIPCPE)-based sensors for the sensitive detection of organic and inorganic environmental pollutants: a review, Trends Environ. Anal. Chem. 32. e00144. https://doi.org/10.1016/j.teac.2021.e00144Mulyaningsih, R.D., Pratiwi, R., Hasanah, A.N. (2023). An Update on the Use of Natural Pigments and Pigment Nanoparticle Adducts for Metal Detection Based on Colour Response. Biosensors. 13. 554. https://doi.org/10.3390/bios13050554.Múnera, M. (27 de noviembre de 2022). Por hallazgo de metales pesados en plantas, fundacion no usa matas de Santurbán. Obtenido de El Tiempo: https://www.eltiempo.com/colombia/santander/plantas-de-santurban-estan-contaminadas-con-metales-pesados-720870Nilsson, J-R., Benitez-Martin, C., Sansom, H-G., Pfeiffer, P., Baladi,T., Le, H-N., Dahlén, A., Magennis, S-W., Wilhelmsson, L-M. (2023). Phys. Chem. Chem. Phys. 25. 20218–20224. https://doi.org/10.1039/D3CP01147JNoureddin, S-A., El-Shishtawy, R., Al-Footy, K-O. (2023). Curcumin analogues and their hybrid molecules as multifunctional drugs. European Journal of Medicinal Chemistry.182. 111631. https://doi.org/10.1016/j.ejmech.2019.111631Omach, Z.; Odhiambo, B.; Owoko, W. (2023). Health Impacts of Mercury Toxicity on Fish in an Aquatic System. Preprints. 2023081908. https://doi.org/10.20944/preprints202308.1908.v1Orteca, G.; Sinnes, J.P.; Piel, M.; Roesch, F.; Ferrari, E.; Asti, M.; Rubagotti, S.; Bednarikova, Z.; Capponi, Z.; Pier, C. (2019). P#115 - 68Ga-Curcumin-Based Bifunctional Ligands for Alzheimer’s Disease Diagnosis. Nuclear Medicine and Biology. 72–73(1). S43–S44. https://doi.org/10.1016/S0969-8051(19)30308-7.Pabón, S., Benítez, R., Sarria, R.A., Gallo, J. (2020). Contaminación del agua por metales pesados, métodos de análisis y tecnologías de remoción. Una revisión. Entre Ciencia e Ingeniería. 14(27). 9-18. http://www.scielo.org.co/pdf/ecei/v14n27/1909-8367-ecei-14-27-9.pdfPaden, R.R., Oracion, J.P.L., De La Rosa, L.B., Lavapiez, M.A.M., Alguno, A.C., Deocaris, D.C., Capangpangan, R.Y. (2021). Design and fabrication of a low-cost curcumin-based paper sensor for rapid ‘‘naked-eye” cyanide sensing. Materials Today: Proceedings. 46(4). 1711-1717. https://doi.org/10.1016/j.matpr.2020.07.374Phatthanawiwat, K.; Boonkanon, C.; Wongniramaikul, W.; Choodum, A. (2022). Catechin and Curcumin Nanoparticle-Immobilized Starch Cryogels as Green Colorimetric Sensors for on-Site Detection of Iron. Sustainable Chemistry and Pharmacy. 2022, 29, 100782. https://doi.org/10.1016/j.scp.2022.100782.Prasad, S.; DuBourdieu, D., Srivastava, A., Kumar, P., Lall, R. (2021). Metal–Curcumin Complexes in Therapeutics: An Approach to Enhance Pharmacological Effects of Curcumin. Int. J. Mol. Sci. 22. 7094. https://doi.org/10.3390/ijms22137094Rai, M., Ingle, A. P., Pandit, R., Paralikar, P., Anasane, N., & Santos, C. A. D. (2020). Curcumin and curcumin-loaded nanoparticles: Antipathogenic and antiparasitic activities. Expert Review of Anti-infective Therapy, 18(4), 367–379. https://doi.org/10.1080/14787210.2020.1730815Rainey, N.E., Moustapha, A., Saric, A., Nicolas, G., Sureau, F., Petit, P.X. (2019). Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation. Cell Death Discovery. 5(150). 2-15. https://doi.org/10.1038/s41420-019-0234-yRathore, M.M.S.; Sharma, P.; Devi, S.; Nagar, J.C.; Khalid, M. (2020). Curcumin: A Review for Health Benefits. Int. J. Res. Rev. 7. 273–290.Rao, T.N. (2018). Chapter 7 Validation of Analytical Methods. Book: Calibration and Validation of Analytical Methods - A Sampling of Current Approaches. Edited by Mark Stauffer. ISBN 978-1-78923-085-7. https://www.intechopen.com/books/6379Rodríguez, J. C. (2019). Síntesis y caracterización de análogos de curcumina y sus complejos metálicos de cobre. Ciudad de México: Universidad Nacional Autónoma de México.Sabzkoohi, H.A., Dodier, V., Kolliopoulos, G. (2023). A validated analytical method to measure metals dissolved in deep eutectic solvents. RSC Adv., 13, 14887. https://pubs.rsc.org/en/content/articlepdf/2023/ra/d3ra02372aSalem, M.A.; El-Shiekh, R.A.; Fernie, A.R.; Alseekh, S.; Zayed, A. (2022). Metabolomics-based profiling for quality assessment and revealing the impact of drying of Turmeric (Curcuma longa L.). Sci. Rep. 12. 10288. https://doi.org/10.3390/molecules27165055Salehi-Babarsad, F., Derikvand, E., Razaz, M., Yousefi, R., Shirmardi, A. (2019). Heavy metal removal by using ZnO/organic and ZnO/ inorganic nanocomposite heterostructures, Int. J. Environ. Anal. Chem. 100(6). 702–719. https://doi.org/10.1080/03067319.2019.1639685Sanchez Arenas, J. C., Tapia López, L., García Meza, M. G., & Ocaranza Sánchez, E. (2022). Compuestos Curcuminoides: Una Posible Solución Natural Para Tratar El Cáncer. Frontera Biotecnológica, 27-32. ISSN: 2448-8461 https://www.revistafronterabiotecnologica.cibatlaxcala.ipn.mx/volumen/vol22/pdf/vol-22-4.pdfSani, A-H., Amanabo, M. (2021). Lead: A concise review of its toxicity, mechanism and health effect. GSC Biological and Pharmaceutical Sciences. 15(01). 055-062. https://doi.org/10.30574/gscbps.2021.15.1.0096Saranya, J., Sreeja, B.S., Padmalaya, G., Fadha, S., Arivanandan, M. (2021). Microwave thermally assisted porous structured cerium oxide/zinc oxide design: fabrication, electrochemical activity towards Pb ions, anticancer assessment in HeLa and VERO cell lines, J. Organ. Organometall. Polym. Mater. 31, 1279–1292. https://link.springer.com/article/10.1007/s10904-020-01809-xServicios técnicos de investigación. (2 de Febrero de 2023). Universidad de Alicante. Obtenido de Espectroscopía ultravioleta visible: https://sstti.ua.es/es/instrumentacion-cientifica/unidad-de-rayos-x-de-monocristal-y-espectroscopias-vibracional-y-optica/espectroscopia-ultravioleta-visible.htmlShakoor, S., Ismail, A., Sabran, M. R., Mohtarrudin, N., Kaka, U., & Nadeem, M. (2021). In-vivo study of synthetic and natural food colors effect on biochemical and immunity parameters. Food Science and Technology, 42, e41420. https://doi.org/10.1590/fst.41420Sharifi-Rad, J., El Rayess, Y., Abi Rizk, A., Sadaka, C., Zgheib, R., Zam, W., Martins, N. (2020). Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and MEdicinal Applications. Frontiers in Pharmacology. 11. 1-23. https://doi.org/10.3389/fphar.2020.01021Sheikhzadeh, E.; Naji-Tabasi, S.; Verdian, A.; Kolahi-Ahari, S. (2022). Equipment-Free and Visual Detection of Pb2+ Ion Based on Curcumin-Modified Bacterial Cellulose Nanofiber. Journal of the Iranian Chemical Society. 19, 283–290. https://doi.org/10.1007/s13738-021-02305-wShin, D.Y.; Lee, S.M.; Jang, Y.; Lee, J.; Lee, C.M.; Cho, E.-M.; Seo, Y.R. (2023). Adverse Human Health Effects of Chromium by Exposure Route: A Comprehensive Review Based on Toxicogenomic Approach. Int. J. Mol. Sci. 24. 3410. https://doi.org/10.3390/ijms24043410Shinozaki, Y., Popov, S., Plenio, H. (2023). Fluorescent organometallic dyads and triads: establishing spatial relationships. Chemical Science. 14. 350-361. https://doi.org/10.1039/D2SC04869HSuhito, I. R., Lee, W., Baek, S., Lee, D., Min, J., & Kim, T.-H. (2019). Rapid and sensitive electrochemical detection of anticancer effects of curcumin on human glioblastoma cells. Sensors and Actuators B: Chemical. 288. 527–534. https://doi.org/10.1016/j.snb.2019.03.031Tabanelli, R.; Brogi, S.; Calderone, V. (2021). Improving Curcumin Bioavailability: Current Strategies and Future Perspectives. Pharmaceutics. 13(10). 1715. https://doi.org/10.3390/pharmaceutics13101715Trivedi, P., & Axe, L. (2000). Modeling Cd and Zn sorption to hydrous metal oxides. Environ. Sci. Technol. 34(11). 2215–2223. https://doi.org/10.1021/es991110cTsuda, T. (2018). Curcumin as a functional food-derived factor: Degradation products, metabolites, bioactivity, and future perspectives. Food Funct. 9. 705–714. https://doi.org/10.1039/C7FO01242JVonnie, J.M.; Ting, B.J.; Rovina, K.; Erna, K.H.; Felicia,W.X.L.; ‘Aqilah, N.M.N.;Wahab, R.A.(2022). Development of Aloe Vera-Green Banana Saba-Curcumin Composite Film for Colorimetric Detection of Ferrum (II). Polymers. 14(12). 2353. https://doi.org/10.3390/polym14122353Wang, B., Wang, L., Chen, Ch., Zhang, Y., Gao, J., Lu, K., Yan,Ch., Nan, G., Li, Y. (2023). A Review on Recent Advances in Peptide-based Fluorescence Probes and their Potential Applications. 8(31). e202302216. https://doi.org/10.1002/slct.202302216Wang, Y., Wang, J-K., Alkhazragi, O., Gutiérrez-Arzaluz, L., Zhang, H., Kang, Ch-H., Khee Ng, T., Bakr, O.M., Mohammed, O.F., Ooi, B.S. (2023). Multifunctional difluoroboron β-diketonate-based luminescent receiver for a high-speed underwater wireless optical communication system. Optics Express. 31(20). 32516-32528. https://doi.org/10.1364/OE.500330Waure, Ch., Bertola, C., Baccarini, G., Chiavarini, M., Mancuso, C. (2023). Exploring the Contribution of Curcumin to Cancer Therapy: A Systematic Review of Randomized Controlled Trials. Pharmaceutics. 15(4). 1275. https://doi.org/10.3390/pharmaceutics15041275Xiaa, J., Xiongb, Y., Minb, S., Li, J. (2022). A review of recent infrared spectroscopy research for paper. Applied Spectroscopy Reviews. https://doi.org/10.1080/05704928.2022.2142939Xie R., Su D., Song Y., Sun P., Mao B., Tian M., Chai F. (2023). The synthesis of gold nanoclusters with high stability and their application in fluorometric detection for Hg2+ and cell imaging. Talanta. 260. 124573. https://doi.org/10.1016/j.talanta.2023.124573Xu, H., Zhang, W., Wang, M. (2022). Bioinspired Fluorescent Polymers: Synthesis, Processing, and Applications. Chinese Journal of Chemistry. 41(4). 458-468. https://doi.org/10.1002/cjoc.202200493Yang, D., Liu, Y., Geng, J., Kou, X., Xin, Z., Lv, M. (2018). Engineering nanomaterials-based biosensors for food safety detection. Biosens. Bioelectron. 106, 122–128. https://doi.org/10.1016/j.bios.2018.01.049Zacharioudaki, D-E., Fitilis, I., Kotti, M. (2022). Review of Fluorescence Spectroscopy in Environmental Quality Applications. Molecules, 27(15), 4801. https://doi.org/10.3390/molecules27154801Zainab, A., Rooh Ullah, M., Tuzen, S-U., Rahim, A., Tawfik, A-S.. (2023). Colorimetric sensing of heavy metals on metal doped metal oxide nanocomposites: A review, Trends in Environmental Analytical Chemistry. 37. e00187. https://doi.org/10.1016/j.teac.2022.e00187.Zhang, Y., Khan, A.R., Fu, M., Zhai, Y., Yu, A., Zha, G. (2019) The progresses in curcuminoids-based metal complexes: especially in cancer therapy. Future Medicinal Chemistry. 11(9). 1035–1056. https://doi.org/10.4155/fmc-2018-0190.THUMBNAIL2024PinzónJennifer.pdf.jpg2024PinzónJennifer.pdf.jpgIM Thumbnailimage/jpeg5164https://repository.usta.edu.co/bitstream/11634/55061/6/2024Pinz%c3%b3nJennifer.pdf.jpg46a650f05d79dec9da7b12cd2eeb4a87MD56open access2024PinzónJennifer1.pdf.jpg2024PinzónJennifer1.pdf.jpgIM Thumbnailimage/jpeg7323https://repository.usta.edu.co/bitstream/11634/55061/7/2024Pinz%c3%b3nJennifer1.pdf.jpg6a232a85ada18c3233c20a665d312518MD57open access2024PinzónJennifer2.pdf.jpg2024PinzónJennifer2.pdf.jpgIM Thumbnailimage/jpeg9785https://repository.usta.edu.co/bitstream/11634/55061/8/2024Pinz%c3%b3nJennifer2.pdf.jpge33fd699f747fb9bf41c5b1ff1e371cbMD58open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-8807https://repository.usta.edu.co/bitstream/11634/55061/5/license.txtaedeaf396fcd827b537c73d23464fc27MD55open accessORIGINAL2024PinzónJennifer.pdf2024PinzónJennifer.pdfTrabajo de gradoapplication/pdf2814738https://repository.usta.edu.co/bitstream/11634/55061/1/2024Pinz%c3%b3nJennifer.pdf4094f5d3a177fff29c38626be1c85b62MD51open access2024PinzónJennifer1.pdf2024PinzónJennifer1.pdfAprobación facultadapplication/pdf174509https://repository.usta.edu.co/bitstream/11634/55061/2/2024Pinz%c3%b3nJennifer1.pdf9188c58fba1b643ae201b5fcdb57f962MD52metadata only access2024PinzónJennifer2.pdf2024PinzónJennifer2.pdfAcuerdo de publicaciónapplication/pdf169744https://repository.usta.edu.co/bitstream/11634/55061/3/2024Pinz%c3%b3nJennifer2.pdf65854aaf6f007025cac067d996c257b0MD53metadata only accessCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8811https://repository.usta.edu.co/bitstream/11634/55061/4/license_rdf217700a34da79ed616c2feb68d4c5e06MD54open access11634/55061oai:repository.usta.edu.co:11634/550612024-05-09 03:15:42.694open accessRepositorio Universidad Santo Tomásnoreply@usta.edu.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 |