Vacunas contra la viruela del simio: una revisión narrativa

La viruela símica es uno de los eventos que ha tenido impacto en la salud pública en tiempos recientes. Esta enfermedad zoonótica tiene como agente causal al virus de la viruela símica y la transmisión puede ocurrir de animales infectados a humanos, de persona a persona y de ambientes contaminados o...

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Autores:
Giraldo Vergara, Maria Yohana
Martelo Alvarino, Salma Andrea
Vega Barcos, Zurisadai
Tipo de recurso:
Review article
Fecha de publicación:
2023
Institución:
Universidad de San Buenaventura
Repositorio:
Repositorio USB
Idioma:
spa
OAI Identifier:
oai:bibliotecadigital.usb.edu.co:10819/12564
Acceso en línea:
https://hdl.handle.net/10819/12564
Palabra clave:
610 - Medicina y salud::616 - Enfermedades
Tesis - bacteriología
Vacunas (viruela de los simios)
Viruela del mono
Viruela símica
Enfermedad zoonótica
Inmunogenicidad vacunal
Virus Vaccinia
Vacuna contra viruela
Virus de la viruela del Simio
Viruela de los Simios
Immunogenicity
Vaccinia virus
Vaccine
Smallpox vaccine
Monkeypox virus
Monkeypox
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
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dc.title.spa.fl_str_mv Vacunas contra la viruela del simio: una revisión narrativa
title Vacunas contra la viruela del simio: una revisión narrativa
spellingShingle Vacunas contra la viruela del simio: una revisión narrativa
610 - Medicina y salud::616 - Enfermedades
Tesis - bacteriología
Vacunas (viruela de los simios)
Viruela del mono
Viruela símica
Enfermedad zoonótica
Inmunogenicidad vacunal
Virus Vaccinia
Vacuna contra viruela
Virus de la viruela del Simio
Viruela de los Simios
Immunogenicity
Vaccinia virus
Vaccine
Smallpox vaccine
Monkeypox virus
Monkeypox
title_short Vacunas contra la viruela del simio: una revisión narrativa
title_full Vacunas contra la viruela del simio: una revisión narrativa
title_fullStr Vacunas contra la viruela del simio: una revisión narrativa
title_full_unstemmed Vacunas contra la viruela del simio: una revisión narrativa
title_sort Vacunas contra la viruela del simio: una revisión narrativa
dc.creator.fl_str_mv Giraldo Vergara, Maria Yohana
Martelo Alvarino, Salma Andrea
Vega Barcos, Zurisadai
dc.contributor.advisor.none.fl_str_mv Castro Orozco, Raimundo
dc.contributor.author.none.fl_str_mv Giraldo Vergara, Maria Yohana
Martelo Alvarino, Salma Andrea
Vega Barcos, Zurisadai
dc.contributor.researchgroup.none.fl_str_mv Grupo de Investigación Microbiología y Ambiente (GIMA) (Cartagena)
dc.subject.ddc.none.fl_str_mv 610 - Medicina y salud::616 - Enfermedades
topic 610 - Medicina y salud::616 - Enfermedades
Tesis - bacteriología
Vacunas (viruela de los simios)
Viruela del mono
Viruela símica
Enfermedad zoonótica
Inmunogenicidad vacunal
Virus Vaccinia
Vacuna contra viruela
Virus de la viruela del Simio
Viruela de los Simios
Immunogenicity
Vaccinia virus
Vaccine
Smallpox vaccine
Monkeypox virus
Monkeypox
dc.subject.other.none.fl_str_mv Tesis - bacteriología
Vacunas (viruela de los simios)
Viruela del mono
Viruela símica
Enfermedad zoonótica
dc.subject.proposal.spa.fl_str_mv Inmunogenicidad vacunal
Virus Vaccinia
Vacuna contra viruela
Virus de la viruela del Simio
Viruela de los Simios
dc.subject.proposal.eng.fl_str_mv Immunogenicity
Vaccinia virus
Vaccine
Smallpox vaccine
Monkeypox virus
Monkeypox
description La viruela símica es uno de los eventos que ha tenido impacto en la salud pública en tiempos recientes. Esta enfermedad zoonótica tiene como agente causal al virus de la viruela símica y la transmisión puede ocurrir de animales infectados a humanos, de persona a persona y de ambientes contaminados o fómites a seres humanos. A partir de mayo de 2022, se confirmaron gran cantidad de pacientes infectados en países no endémicos de todo el mundo, lo que puso en alerta a la Organización Mundial de la salud (OMS). Para prevenir esta patología o como profilaxis, la OMS recomienda la vacunación para personas infectadas, contactos o personal en riesgo de contagio. Las vacunas empleadas originalmente se crearon para combatir la viruela, las cuales pueden ser de primera, segunda y tercera generación. Debido a la emergencia internacional por este brote, se aprobaron para combatir la viruela del simio las vacunas de segunda y de tercera generación. La vacuna de segunda generación, correspondiente a ACAM2000, virus vaccinia vivo replicante genera efectos adversos, y con el fin de disminuir la capacidad de replicación y eventos secundarios, se crearon las de tercera generación, MVA-BN virus vaccinia vivo no replicante y LC16 virus vaccinia vivo mínimamente replicante. El acceso a estas vacunas es limitado ya que hacen parte de las reservas estratégicas de los países. La eficacia de la vacunación está basada en su evaluación en biomodelos como los monos, pero la evidencia de la efectividad en humanos no ha sido comprobada.
publishDate 2023
dc.date.accessioned.none.fl_str_mv 2023-10-10T14:44:49Z
dc.date.available.none.fl_str_mv 2023-10-10T14:44:49Z
dc.date.issued.none.fl_str_mv 2023-03-02
dc.type.spa.fl_str_mv Trabajo de grado - Pregrado
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dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_dcae04bc
dc.type.content.spa.fl_str_mv Text
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dc.identifier.citation.none.fl_str_mv Giraldo Vergara, M. Y., Martelo Alvarino, S. A. & Vega Barcos, Z. (2023). Vacunas contra la viruela del simio: una revisión narrativa. [Trabajo de grado de Bacteriología]. Universidad de San Buenaventura, Cartagena.
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identifier_str_mv Giraldo Vergara, M. Y., Martelo Alvarino, S. A. & Vega Barcos, Z. (2023). Vacunas contra la viruela del simio: una revisión narrativa. [Trabajo de grado de Bacteriología]. Universidad de San Buenaventura, Cartagena.
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WHO. WHO Director-General’s statement at the press conference following IHR Emergency Committee regarding the multi-country outbreak of monkeypox - 23 July 2022. In 2022 [cited 2023 Jan 19]. Available from: https://www.who.int/director-general/speeches/detail/who-director-general-s statement-on-the-press-conference-following-IHR-emergency-committee regarding-the-multi--country-outbreak-of-monkeypox--23-july-2022
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spelling Castro Orozco, Raimundo10b5ca18-0aaf-4c91-a9cc-46a92a069813-1Giraldo Vergara, Maria Yohana8f871380-856d-447d-8bf0-c1a3cce5dc0f-1Martelo Alvarino, Salma Andreaafdf0445-76dd-478d-94ac-9ea15ce5d6bc-1Vega Barcos, Zurisadaifd2b7a5e-9f57-4cf5-9593-b9a71082f09b-1Grupo de Investigación Microbiología y Ambiente (GIMA) (Cartagena)2023-10-10T14:44:49Z2023-10-10T14:44:49Z2023-03-02La viruela símica es uno de los eventos que ha tenido impacto en la salud pública en tiempos recientes. Esta enfermedad zoonótica tiene como agente causal al virus de la viruela símica y la transmisión puede ocurrir de animales infectados a humanos, de persona a persona y de ambientes contaminados o fómites a seres humanos. A partir de mayo de 2022, se confirmaron gran cantidad de pacientes infectados en países no endémicos de todo el mundo, lo que puso en alerta a la Organización Mundial de la salud (OMS). Para prevenir esta patología o como profilaxis, la OMS recomienda la vacunación para personas infectadas, contactos o personal en riesgo de contagio. Las vacunas empleadas originalmente se crearon para combatir la viruela, las cuales pueden ser de primera, segunda y tercera generación. Debido a la emergencia internacional por este brote, se aprobaron para combatir la viruela del simio las vacunas de segunda y de tercera generación. La vacuna de segunda generación, correspondiente a ACAM2000, virus vaccinia vivo replicante genera efectos adversos, y con el fin de disminuir la capacidad de replicación y eventos secundarios, se crearon las de tercera generación, MVA-BN virus vaccinia vivo no replicante y LC16 virus vaccinia vivo mínimamente replicante. El acceso a estas vacunas es limitado ya que hacen parte de las reservas estratégicas de los países. La eficacia de la vacunación está basada en su evaluación en biomodelos como los monos, pero la evidencia de la efectividad en humanos no ha sido comprobada.Monkeypox is one of the events that has had an impact on public health in the year 2022. This zoonotic disease is caused by the monkeypox virus and transmission can occur from infected animals to humans, from person to person, and from contaminated environments or fomites to humans. As of May 2022, many infected patients were confirmed in non-endemic countries around the world, which put the WHO on alert. To prevent this pathology or as prophylaxis, WHO recommends vaccination for infected persons, contacts, or personnel at risk of infection. The vaccines originally used were created to combat smallpox, which can be of first, second and third generation. Due to the international emergency caused by this outbreak, second and third generation vaccines were approved to combat monkeypox. The second-generation vaccine, corresponding to ACAM2000, live replicating vaccinia virus, generates adverse effects, and to reduce the replication capacity and secondary events, the third-generation vaccines, MVA-BN live non-replicating vaccinia virus and LC16 live minimally replicating vaccinia virus, were created. Access to these vaccines is limited since they are part of the countries' strategic reserves. The efficacy of vaccination is based on its evaluation in biomodels such as monkeys, but evidence of effectiveness in humans has not been provenPregradoBacteriólogo27 páginasapplication/pdfGiraldo Vergara, M. Y., Martelo Alvarino, S. A. & Vega Barcos, Z. (2023). Vacunas contra la viruela del simio: una revisión narrativa. [Trabajo de grado de Bacteriología]. 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LC16m8, a highly attenuated vaccinia virus vaccine lacking expression of the membrane protein B5R, protects monkeys from monkeypox. J Virol. 2006 Jun;80(11):5179–88.Kennedy JS, Gurwith M, Dekker CL, Frey SE, Edwards KM, Kenner J, et al. Safety and Immunogenicity of LC16m8, an Attenuated Smallpox Vaccine in Vaccinia-Naive Adults. J Infect Dis [Internet]. 2011 Nov 1;204(9):1395–402. Available from: https://doi.org/10.1093/infdis/jir527MinSalud. ABECÉ VIRUELA SÍMICA [Internet]. 2022 Jun [cited 2023 Jan 18]. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/ED/abece-viruela-simica-mono.pdMinSalud. Panorama de la viruela símica en Colombia y el mundo. Boletín de Prensa No 525 de 2022 [Internet]. 2022 Nov 1 [cited 2023 Jan 19]; Available from: https://www.minsalud.gov.co/Paginas/Panorama-de-la-viruela-simica en-Colombia-y-el-mundo.aspxMinSalud. Minsalud suscribió acuerdo con Japón para recibir vacunas contra la viruela símica. Boletín de Prensa No 586 de 2022 [Internet]. 2022 Dec 2 [cited 2023 Jan 19]; Available from: https://www.minsalud.gov.co/Paginas/Minsalud suscribio-acuerdo-con-Japon-para-recibir-vacunas-contra-la-viruela simica.aspinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/610 - Medicina y salud::616 - EnfermedadesTesis - bacteriologíaVacunas (viruela de los simios)Viruela del monoViruela símicaEnfermedad zoonóticaInmunogenicidad vacunalVirus VacciniaVacuna contra viruelaVirus de la viruela del SimioViruela de los SimiosImmunogenicityVaccinia virusVaccineSmallpox vaccineMonkeypox virusMonkeypoxVacunas contra la viruela del simio: una revisión narrativaTrabajo de grado - Pregradohttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_7a1fTextinfo:eu-repo/semantics/bachelorThesishttp://purl.org/redcol/resource_type/TPinfo:eu-repo/semantics/acceptedVersionComunidad Científica y AcadémicaPublicationORIGINALVacunas contra la viruela_Maria Giraldo V_2023.pdfVacunas contra la viruela_Maria Giraldo V_2023.pdfapplication/pdf233250https://bibliotecadigital.usb.edu.co/bitstreams/069d97af-03ce-4bcb-a01f-c1cb0fe4aa72/download6d4a2c13e9b3240dada48457615e6263MD51Formato_Publicacion_Vacunas contra la viruela_Maria Giraldo V_2023.pdfFormato_Publicacion_Vacunas contra la viruela_Maria Giraldo V_2023.pdfapplication/pdf243993https://bibliotecadigital.usb.edu.co/bitstreams/f4a1149e-8ff6-426a-9550-f0a800225687/downloadd1c5e5caf9596d8e9bae512212ec691fMD52CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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