Caracterización reacciones adversas e intoxicaciones por inhibidores selectivos de recapacitación de serotonina notificados en Bogotá 2008 al 2016

Selective Serotonin Reuptake Inhibitors (SSRIs) are drugs of synthetic origin; insurance, employees for first-line treatment in pathologies such as depression and other disorders of the state of the mood. SSRIs are absorbed orally, metabolized by the liver, have different potencies and half-lives, inhibit cytochrome P450 enzymes. The adverse reactions reported by the district pharmacovigilance program reported 66 cases during the years 2008 to 2016 at the time of the analysis showed that none of them showed serious affections in the patient's health in which it should be noted that no case presented hospitalization and None of them were in a state of gestation, additional were found 56 cases of adverse reactions, on the other hand it was shown that women are more likely to present SRAM. SSRI drug poisonings during the years 2008 to 2016 notified to SIVIGILA provide information in an effective and truthful manner on the events that affect the health of the population, with the aim of taking preventive measures, posing corrective actions and preventing poisoning by practices Untimely. They have presented a significant increase during the years mentioned; In the present study, poisonings were characterized where it was found that during this period a total of 329 notifications were made, of which 82.1% had SSRI intoxication causal agent and 17.9% had as a causal agent mixture with other substances And psychoactive). There are no cases of mortality.

• Autores: Alayón Barbosa, Julieth Hasbleidy; Gómez Avila, Luz Milena
• Tipo de recurso: Trabajo de grado de pregrado
• Fecha de publicación: 2017
• Institución: Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
• Repositorio: Repositorio Institucional UDCA
• Idioma: spa
• OAI Identifier: oai:repository.udca.edu.co:11158/715
• Acceso en línea: https://repository.udca.edu.co/handle/11158/715
• Palabra clave: Intoxicación; Reacciones adversas; Inhibidores Selectivos Recaptación de Serotonina; Medicamentos; Inhibidores selectivos -- Efectos secundarios; Serotonina -- Investigaciones
• Rights: closedAccess
• License: Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales