Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos
95 páginas : ilustraciones, gráficas
- Autores:
-
Strucky Byler, Lucas Benjamín
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
- Repositorio:
- Repositorio Institucional UDCA
- Idioma:
- spa
- OAI Identifier:
- oai:repository.udca.edu.co:11158/1056
- Acceso en línea:
- https://repository.udca.edu.co/handle/11158/1056
- Palabra clave:
- Polimorfismo
Rendimiento deportivo
Pesistas - Asuntos médicos y sanitarios
Ciencias del deporte
Polimorfismo ACTN3 R577X
Rendimiento deportivo
Halterofilia
- Rights
- openAccess
- License
- Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales
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Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| title |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| spellingShingle |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos Polimorfismo Rendimiento deportivo Pesistas - Asuntos médicos y sanitarios Ciencias del deporte Polimorfismo ACTN3 R577X Rendimiento deportivo Halterofilia |
| title_short |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| title_full |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| title_fullStr |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| title_full_unstemmed |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| title_sort |
Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianos |
| dc.creator.fl_str_mv |
Strucky Byler, Lucas Benjamín |
| dc.contributor.advisor.spa.fl_str_mv |
Rodríguez Buitrago, Jeansy Alonso |
| dc.contributor.author.spa.fl_str_mv |
Strucky Byler, Lucas Benjamín |
| dc.subject.lemb.spa.fl_str_mv |
Polimorfismo Rendimiento deportivo Pesistas - Asuntos médicos y sanitarios Ciencias del deporte |
| topic |
Polimorfismo Rendimiento deportivo Pesistas - Asuntos médicos y sanitarios Ciencias del deporte Polimorfismo ACTN3 R577X Rendimiento deportivo Halterofilia |
| dc.subject.proposal.spa.fl_str_mv |
Polimorfismo ACTN3 R577X Rendimiento deportivo Halterofilia |
| description |
95 páginas : ilustraciones, gráficas |
| publishDate |
2018 |
| dc.date.accessioned.spa.fl_str_mv |
2018-09-25T16:04:32Z |
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2018-09-25T16:04:32Z |
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2018 |
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Trabajo de grado - Pregrado |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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https://repository.udca.edu.co/handle/11158/1056 |
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CD005 S77a 2018 |
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Ahmetov, I., Donnikov, A., & Trofimov, D. (2014). ACTN3 GENOTYPE IS ASSOCIATED WITH TESTOSTERONE LEVELS OF ATHLETES. Biology of Sport, 31(2), 105-108. https://doi.org/10.5604/20831862.1096046 Ahmetov, I. I., & Fedotovskaya, O. N. (2015). Current Progress in Sports Genomics. En Advances in Clinical Chemistry (1.a ed., Vol. 70, pp. 247-314). Elsevier Inc. https://doi.org/10.1016/bs.acc.2015.03.003 Alfred, T., Ben-Shlomo, Y., Cooper, R., Hardy, R., Cooper, C., Deary, I. J., … Day, I. N. M. (2011). ACTN3 genotype, athletic status, and life course physical capability: metaanalysis of the published literature and findings from nine studies. Human Mutation, 32(9), 1008-1018. https://doi.org/10.1002/humu.21526 Amorim, C. E. G., Acuña-Alonzo, V., Salzano, F. M., Bortolini, M. C., & Hünemeier, T. (2015). Differing Evolutionary Histories of the ACTN3*R577X Polymorphism among the Major Human Geographic Groups. PLOS ONE, 10(2), e0115449. https://doi.org/10.1371/journal.pone.0115449 Balkó, I., Balkó, Š., Týnková, H., & Kohlíková, E. (2015). The Occurence of R577X Polymorphism of ACTN3 Gene in a Selected Group of Elite Fencers. AUC KINANTHROPOLOGICA, 50(2), 5-12. https://doi.org/10.14712/23366052.2015.11 Bell, W., Colley, J. P., Evans, W. D., Darlington, S. E., & Cooper, S.-M. (2012). ACTN3 genotypes of Rugby Union players: Distribution, power output and body composition. Annals of Human Biology, 39(1), 19-27. https://doi.org/10.3109/03014460.2011.632648 Berman, Y., & North, K. N. (2010). A Gene for Speed: The Emerging Role of α-Actinin-3 in Muscle Metabolism. Physiology, 25(4), 250-259. https://doi.org/10.1152/physiol.00008.2010 Bouchard, C., Rankinen, T., & Timmons, J. A. (2011). Genomics and Genetics in the Biology of Adaptation to Exercise. En Comprehensive Physiology (Vol. 1, pp. 1603-1648). Hoboken, NJ, USA: John Wiley & Sons, Inc.https://doi.org/10.1002/cphy.c100059 Caratachea, M. A. C. (2007). Polimorfismos geneticos: Importancia y aplicaciones. Revista del Instituto Nacional de Enfermedades Respiratorias, 20(3), 213-221. Chiu, L. Z. F., & K.Schilling, B. (2005). A Primer on Weightlifting : From Sport to Sports Training. National Strength and Conditioning Association, 27(1), 42-48. Cięszczyk, P., Eider, J., Ostanek, M., Arczewska, A., Leońska-Duniec, A., Sawczyn, S., … Krupecki, K. (2011). Association of the ACTN3 R577X Polymorphism in Polish Power-Orientated Athletes. Journal of Human Kinetics, 28(1), 55-61. https://doi.org/10.2478/v10078-011-0022-0 Clarkson, P. M., Devaney, J. M., Gordish-Dressman, H., Thompson, P. D., Hubal, M. J., Urso, M., … Hoffman, E. P. (2005). ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women. Journal of Applied Physiology, 99(1), 154-163. https://doi.org/10.1152/japplphysiol.01139.2004 Cooper, G. M. (2000). Actin, Myosin, and Cell Movement. Recuperado a partir de https://www.ncbi.nlm.nih.gov/books/NBK9961/ Döring, F. E., Onur, S., Geisen, U., Boulay, M. R., Pérusse, L., Rankinen, T., … Bouchard, C. (2010). ACTN3 R577X and other polymorphisms are not associated with elite endurance athlete status in the Genathlete study. Journal of Sports Sciences, 28(12), 1355-1359. https://doi.org/10.1080/02640414.2010.507675 Druzhevskaya, A. M., Ahmetov, I. I., Astratenkova, I. V., & Rogozkin, V. A. (2008). Association of the ACTN3 R577X polymorphism with power athlete status in Russians. European Journal of Applied Physiology, 103(6), 631-634. https://doi.org/10.1007/s00421-008-0763-1 Ellard, S., Baple, E. L., Owens, M., Eccles, D. M., Abbs, S., & Zandra, C. (2017). ACGS Best Practice Guidelines for Variant Classification 2017. Association for Clinical Genetic Science, 1-12. Eynon, N., Duarte, J. A., Oliveira, J., Sagiv, M., Yamin, C., Meckel, Y., … Goldhammer, E. (2009). ACTN3 R577X Polymorphism and Israeli Top-level Athletes. International Journal of Sports Medicine, 30(9), 695-698. https://doi.org/10.1055/s-0029-1220731 Eynon, N., Ruiz, J. R., Femia, P., Pushkarev, V. P., Cieszczyk, P., MaciejewskaKarlowska, A., … Lucia, A. (2012). The ACTN3 R577X Polymorphism across Three Groups of Elite Male European Athletes. PLoS ONE, 7(8), e43132. https://doi.org/10.1371/journal.pone.0043132 Fry, A. C., Schilling, B. K., Staron, R. S., Hagerman, F. C., Hikida, R. S., & Thrush, J. T. (2003). Muscle fiber characteristics and performance correlates of male Olympic-style weightlifters. Journal of strength and conditioning research, 17(4), 746-54. Recuperado a partir de http://www.ncbi.nlm.nih.gov/pubmed/14666943 Garatachea, N., Verde, Z., Santos-Lozano, A., Yvert, T., Rodriguez-Romo, G., Sarasa, F. J., … Lucia, A. (2014). ACTN3 R577X Polymorphism and Explosive Leg-Muscle Power in Elite Basketball Players. International Journal of Sports Physiology and Performance, 9(2), 226-232. https://doi.org/10.1123/ijspp.2012-0331 Gautel, M., & Djinovic-Carugo, K. (2016). The sarcomeric cytoskeleton: from molecules to motion. Journal of Experimental Biology, 219(2), 135-145. https://doi.org/10.1242/jeb.124941 Ginevičienė, V., Pranckevičienė, E., Milašius, K., & Kučinskas, V. (2010). Relating fitness phenotypes to genotypes in Lithuanian elite athletes. Acta medica Lituanica, 17(1), 1- 10. https://doi.org/10.2478/v10140-010-0001-0 Grenda, A., Leońska-Duniec, A., Kaczmarczyk, M., Ficek, K., Król, P., Cięszczyk, P., & Żmijewski, P. (2014). Interaction Between ACE I/D and ACTN3 R557X Polymorphisms in Polish Competitive Swimmers. Journal of Human Kinetics, 42(1), 127-36. https://doi.org/10.2478/hukin-2014-0067 Hernandez Sampieri, R., Fernandez Collado, C., & Baptista Lucio, M. del P. (2010). Metodología de la investigación. Metodología de la investigación. https://doi.org/- ISBN 978-92-75-32913-9 Hogarth, M. W., Garton, F. C., Houweling, P. J., Tukiainen, T., Lek, M., Macarthur, D. G., … North, K. N. (2016). Analysis of the ACTN3 heterozygous genotype suggests that α-actinin-3 controls sarcomeric composition and muscle function in a dose-dependent fashion. Human Molecular Genetics, 25(5), 866-877. https://doi.org/10.1093/hmg/ddv613 Holdys, J., Stanisławski, D., Kryściak, J., & Gronek, P. (2011). POLYMORPHISM OF THE α-ACTN3 GENE IN INDIVIDUALS PRACTISING DIFFERENT SPORTS DISCIPLINES. Biology of Sport, 28(2), 101-106. https://doi.org/10.5604/942738 Hydock, D. (2001). The Weightlifting Pull in Power Development. Strength & Conditioning Journal, 23(1), 32-37. Instituto Nacional de Investigación del Genoma Humano. (s. f.). Talking Glossary of Genetic Terms. Recuperado 13 de abril de 2017, a partir de https://www.genome.gov/glossary/index.cfm?id=52&textonly=true IWF. (2017). Sinclair Coefficient - International Weightlifting Federation. Recuperado 30 de enero de 2018, a partir de http://www.iwf.net/weightlifting_/sinclair-coefficient/ Janz, J., & Malone, M. (2008). Training Explosiveness: Weightlifting and Beyond. Strength and Conditioning Journal, 30(6), 14-22. https://doi.org/10.1519/SSC.0b013e31818e2f13 Jastrzebski, Z., Leonska-Duniec, A., Kolbowicz, M., & Tomiak, T. (2014). Association of the ACTN3 R577X polymorphism in Polish rowers. Baltic Journal of Health and Physical Activity, 6(3), 205-210. https://doi.org/10.2478/bjha-2014-0019 Karp, G. (2011). Biologia celular y molecular (6a. ed.). Mc Graw Hill. Recuperado a partir de http://bibliobd.udca.edu.co:2145 Kikuchi, N., Ueda, D., Min, S., Nakazato, K., & Igawa, S. (2013). The ACTN3 XX Genotype ’ s Underrepresentation in Japanese Elite Wrestlers, 57-61. Kim, H., Song, K., & Kim, C. (2014). The ACTN3 R577X variant in sprint and strength performance. Journal of Exercise Nutrition and Biochemistry, 18(4), 347-353. https://doi.org/10.5717/jenb.2014.18.4.347 Kothari, S. T., Chheda, P., Chawla, S., Chatterjee, L., Chaudhry, S. K., & Das, B. R. (2011). ACTN3 R577X Polymorphism in Asian Indian Athletes. International Journal of Human Genetics, 11(3), 149-153. https://doi.org/10.1080/09723757.2011.11886137 Li, Y., Wang, L., Yi, L., Liu, J., Hu, Y., Lu, Y., & Wang, M. (2017). ACTN3 R577X genotype and performance of elite middle-long distance swimmers in China. Biology of Sport, 1(34), 39-43. https://doi.org/10.5114/biolsport.2017.63731 Lodish, H., Berk, A., Zipursky, S. L., Matsudaira, P., Baltimore, D., & Darnell, J. (2000). Muscle: A Specialized Contractile Machine. W. H. Freeman. W. H. Freeman. Recuperado a partir de https://www.ncbi.nlm.nih.gov/books/NBK21670/ Lucia, A., Gómez-Gallego, F., Santiago, C., Bandrés, F., Earnest, C., Rabadán, M., … Foster, C. (2006). ACTN3 Genotype in Professional Endurance Cyclists. 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International Journal of Sports Medicine, 35(2), 172-177. https://doi.org/10.1055/s-0033-1347171 Mills, M. (2001). Differential expression of the actin-binding proteins, alpha-actinin-2 and - 3, in different species: implications for the evolution of functional redundancy. Human Molecular Genetics, 10(13), 1335-1346. https://doi.org/10.1093/hmg/10.13.1335 Murphy, A. C. H., & Young, P. W. (2015). The actinin family of actin cross-linking proteins – a genetic perspective. Cell & Bioscience, 5(1), 49. https://doi.org/10.1186/s13578-015-0029-7 National Human Genome Research Institute. (2015). Estudios de asociación en todo el genoma. Recuperado 1 de mayo de 2017, a partir de https://www.genome.gov/27562846/estudios-de-asociacin-en-todo-el-genoma/ Niemi, A., & Majamaa, K. (2005). Mitochondrial DNA and ACTN3 genotypes in Finnish elite endurance and sprint athletes, 965-969. https://doi.org/10.1038/sj.ejhg.5201438 NSW Goverment. (2012). Variations in the Genetic Code. Recuperado a partir de www.genetics.edu.au Pagon, R. A., Adam, M. P., Ardinger, H. H., Wallace, S. E., Amemiya, A., Bean, L. J., … Stephens, K. (2017). GeneReviews Glossary. Recuperado a partir de https://www.ncbi.nlm.nih.gov/books/NBK5191/ Papadimitriou, I. D., Papadopoulos, C., Kouvatsi, A., & Triantaphyllidis, C. (2008). The ACTN3 gene in elite greek track and field athletes. International Journal of Sports Medicine. https://doi.org/10.1055/s-2007-965339 Richards, S., Aziz, N., Bale, S., Bick, D., Das, S., Gastier-Foster, J., … Rehm, H. L. (2015). Standards and guidelines for the interpretation of sequence variants: A joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genetics in Medicine, 17(5), 405-424. https://doi.org/10.1038/gim.2015.30 Roth, S. M., Walsh, S., Liu, D., Metter, E. J., Ferrucci, L., & Hurley, B. F. (2008). The ACTN3 R577X nonsense allele is under-represented in elite-level strength athletes. European Journal of Human Genetics. https://doi.org/10.1038/sj.ejhg.5201964 Ruiz, J. R., Fernández del Valle, M., Verde, Z., Díez-Vega, I., Santiago, C., Yvert, T., … Lucia, A. (2011). ACTN3 R577X polymorphism does not influence explosive leg muscle power in elite volleyball players. Scandinavian Journal of Medicine & Science in Sports, 21(6), e34-e41. https://doi.org/10.1111/j.1600-0838.2010.01134.x Santiago, C., Rodríguez-Romo, G., Gómez-Gallego, F., González-Freire, M., Yvert, T., Verde, Z., … Lucia, A. (2010). Is there an association between ACTN3 R577X polymorphism and muscle power phenotypes in young, non-athletic adults? Scandinavian Journal of Medicine & Science in Sports, 20(5), 771-778. https://doi.org/10.1111/j.1600-0838.2009.01017.x Schiaffino, S., & Reggiani, C. (2011). Fiber Types in Mammalian Skeletal Muscles. Physiological Reviews, 91(4), 1447-1531. https://doi.org/10.1152/physrev.00031.2010 Scott, R. A., Irving, R., Irwin, L., Morrison, E., Charlton, V., Austin, K., … Pitsiladis, Y. P. (2010). ACTN3 and ACE genotypes in elite Jamaican and US sprinters. Medicine and Science in Sports and Exercise. https://doi.org/10.1249/MSS.0b013e3181ae2bc0 Stone, M. H., Pierce, K. C., Sands, W. A., & Stone, M. E. (2006). Weightlifting : A Brief Overview, 28(1), 50-66. U.S. National Library of Medicine. (2015). Mutations and Health. Help Me Understand Genetics. Recuperado a partir de https://ghr.nlm.nih.gov Ulucan, K., Göle, S., Altindas, N., & Güney, A. I. (2013). Preliminary Findings of αActinin-3 Gene Distribution in Elite Turkish Wind Surfers. Balkan Journal of Medical Genetics, 16(1), 69-72. https://doi.org/10.2478/bjmg-2013-0020 Wessner, B., Stuparits, P., Fail, C., Pavic, F., Tschan, H., & Bachl, N. (2016). Genetic polymorphisms in alpha-actinin 3 and - adrenoceptor beta genes in Austrian elite athletes and healthy controls. Swiss Sports & Exercise Medicine, 64(4), 13-19. Yang, N., MacArthur, D. G., Gulbin, J. P., Hahn, A. G., Beggs, A. H., Easteal, S., & North, K. (2003). ACTN3 Genotype Is Associated with Human Elite Athletic Performance. The American Journal of Human Genetics, 73(3), 627-631. https://doi.org/10.1086/377590 |
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Rodríguez Buitrago, Jeansy AlonsoStrucky Byler, Lucas Benjamín2018-09-25T16:04:32Z2018-09-25T16:04:32Z2018https://repository.udca.edu.co/handle/11158/1056CD005 S77a 201895 páginas : ilustraciones, gráficasIntroducción: El gen ACTN3 codifica la expresión de la proteína alfa actinina 3 en la línea Z en el sarcómero muscular de las fibras de contracción rápida. Una mutación en el gen produce un alelo X con deficiencia total de la proteína en el musculo resultando en 3 genotipos posibles que son el RR, RX y XX. Estas versiones alternativas del gen se conocen como el polimorfismo ACTN3 R577X. Las implicaciones del polimorfismo ya han sido estudiadas en varios deportes en donde se ha encontrado una relación entre la presencia de alfa actinina 3 y el rendimiento deportivo en potencia y velocidad, sin embargo no se encontraron investigaciones realizadas en población Colombiana. Materiales y Métodos: Se evaluaron 26 muestras de sangre de levantadores de pesas colombianos de alto rendimiento para determinar la presencia del polimorfismo ACTN3 R577X. Resultados: Se encontró una frecuencia del genotipo en la población atleta de 50% de genotipo RR, 35% de genotipo RX y 15% de genotipo XX. Por otra parte, el análisis del rendimiento deportivo reportó que el 21% de la muestra había ganado una medalla olímpica o mundial y que de ellos el 71% poseían el genotipo RX y el 29% RR. Además, se encontró que los atletas medallistas tenían rendimientos superiores tanto en peso levantado (arranque p= 0,00042, envión p= 0,00017 y total p= 0,00049) como por coeficiente Sinclair (p=0,00059). El análisis de los subgrupos genotípicos encontró un rendimiento superior para el genotipo RX en comparación con XX y RR en especial en las categorías livianas <77Kg tanto en peso levantado (RX vs RR en envión p=0,0310 y total p= 0,0228 y RX vs XX en arranque p=0,0044, envión p=0,0303 y total p=0,0027) como en el coeficiente Sinclair (RX vs XX p=0,0028 en hombres). Conclusión: los resultados sugieren una relación del genotipo RX con el rendimiento de fuerza-potencia especialmente en un deporte donde se compite por categorías de peso. Esto sugiere una ventaja del genotipo RX en el rendimiento deportivo en la halterofilia, en comparación con los genotipos RR y XX.Incluye bibliografíaPregradoProfesional en Ciencias del Deporteapplication/pdfspaDerechos Reservados - Universidad de Ciencias Aplicadas y Ambientaleshttps://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)http://purl.org/coar/access_right/c_abf2Análisis exploratorio de la relación entre el polimorfismo ACTN3 R577X y el rendimiento deportivo en levantadores de pesas colombianosTrabajo de grado - Pregradohttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/publishedVersionTexthttp://purl.org/redcol/resource_type/TPhttp://purl.org/coar/version/c_970fb48d4fbd8a85PolimorfismoRendimiento deportivoPesistas - Asuntos médicos y sanitariosCiencias del deportePolimorfismo ACTN3 R577XRendimiento deportivoHalterofiliaAhmetov, I., Donnikov, A., & Trofimov, D. 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The American Journal of Human Genetics, 73(3), 627-631. https://doi.org/10.1086/377590Facultad de Ciencias de la SaludCiencias del DeportePublicationORIGINALANÁLISIS EXPLORATORIO DE LA RELACIÓN ENTRE EL POLIMORFISMO ACTN3 R577X Y EL RENDIMIENTO DEPORTIVO.pdfANÁLISIS EXPLORATORIO DE LA RELACIÓN ENTRE EL POLIMORFISMO ACTN3 R577X Y EL RENDIMIENTO DEPORTIVO.pdfapplication/pdf1623091https://repository.udca.edu.co/bitstreams/e045efb8-29e0-4aec-8a23-175fdeb210f3/download04b8f79824529e38e12550c45407bba9MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-814775https://repository.udca.edu.co/bitstreams/d085e960-e805-46ba-9a06-70b9cf469e06/downloadf661acf14bedbf9f5d13897a0387e751MD52TEXTANÁLISIS EXPLORATORIO DE LA RELACIÓN ENTRE EL POLIMORFISMO ACTN3 R577X Y EL RENDIMIENTO DEPORTIVO.pdf.txtANÁLISIS EXPLORATORIO DE LA RELACIÓN ENTRE EL POLIMORFISMO ACTN3 R577X Y EL RENDIMIENTO DEPORTIVO.pdf.txtExtracted 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en las Obras Colectivas;
b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda;
c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas.Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).
4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:
a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).
b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.
c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.
d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:
i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.
ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.
e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, Acinpro), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.
5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.
6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.
7. Término.
a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.
b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.
8. Varios.
a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.
b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.
c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.
d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.

 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