The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019

Background: The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27 EU countries in 2019, and compares them with those...

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Autores:
Santos, João Vasco
Padron-Monedero, Alicia
Bikbov, Boris
Matias de Oliveira, Alecsandra
Plass, Dietrich
Mechili, Enkeleint A.
GAZZELLONI, Federica
Fischer, Florian
Sulo, Gerhard
Ngwa, Che Henry
Noguer-Zambrano, Isabel
Penalvo, Jose L
Tipo de recurso:
Article of investigation
Fecha de publicación:
2024
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
eng
OAI Identifier:
oai:repository.udca.edu.co:11158/5820
Acceso en línea:
https://repository.udca.edu.co/handle/11158/5820
https://doi.org/10.1186/s12889-024-18529-3
Palabra clave:
360 - Problemas y servicios sociales; asociaciones::362 - Problemas sociales y servicios para grupo de personas
Mujeres
Hombres
Costo de la Enfermedad
Union Europea
Carga Global de Enfermedades
Estado de Salud
Esperanza de Vida
Años de vida Ajustados por la Incapacidad
Rights
License
https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.es
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network_name_str Repositorio Institucional UDCA
repository_id_str
dc.title.none.fl_str_mv The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
title The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
spellingShingle The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
360 - Problemas y servicios sociales; asociaciones::362 - Problemas sociales y servicios para grupo de personas
Mujeres
Hombres
Costo de la Enfermedad
Union Europea
Carga Global de Enfermedades
Estado de Salud
Esperanza de Vida
Años de vida Ajustados por la Incapacidad
title_short The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
title_full The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
title_fullStr The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
title_full_unstemmed The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
title_sort The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019
dc.creator.fl_str_mv Santos, João Vasco
Padron-Monedero, Alicia
Bikbov, Boris
Matias de Oliveira, Alecsandra
Plass, Dietrich
Mechili, Enkeleint A.
GAZZELLONI, Federica
Fischer, Florian
Sulo, Gerhard
Ngwa, Che Henry
Noguer-Zambrano, Isabel
Penalvo, Jose L
dc.contributor.author.none.fl_str_mv Santos, João Vasco
Padron-Monedero, Alicia
Bikbov, Boris
Matias de Oliveira, Alecsandra
Plass, Dietrich
Mechili, Enkeleint A.
GAZZELLONI, Federica
Fischer, Florian
Sulo, Gerhard
Ngwa, Che Henry
Noguer-Zambrano, Isabel
Penalvo, Jose L
dc.subject.ddc.none.fl_str_mv 360 - Problemas y servicios sociales; asociaciones::362 - Problemas sociales y servicios para grupo de personas
topic 360 - Problemas y servicios sociales; asociaciones::362 - Problemas sociales y servicios para grupo de personas
Mujeres
Hombres
Costo de la Enfermedad
Union Europea
Carga Global de Enfermedades
Estado de Salud
Esperanza de Vida
Años de vida Ajustados por la Incapacidad
dc.subject.lemb.none.fl_str_mv Mujeres
Hombres
dc.subject.decs.none.fl_str_mv Costo de la Enfermedad
Union Europea
Carga Global de Enfermedades
Estado de Salud
Esperanza de Vida
Años de vida Ajustados por la Incapacidad
description Background: The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27 EU countries in 2019, and compares them with those in 2010. Methods: We used the Global Burden of Disease 2019 study estimates and 95% uncertainty intervals for the whole EU and each country to evaluate age-standardised death, years of life lost (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) rates for Level 2 causes, as well as life expectancy and healthy life expectancy (HALE). Results: In 2019, the age-standardised death and DALY rates in the EU were 465.8 deaths and 20,251.0 DALYs per 100,000 inhabitants, respectively. Between 2010 and 2019, there were significant decreases in age-standardised death and YLL rates across EU countries. However, YLD rates remained mainly unchanged. The largest decreases in age-standardised DALY rates were observed for “HIV/AIDS and sexually transmitted diseases” and “transport injuries” (each -19%). “Diabetes and kidney diseases” showed a significant increase for age-standardised DALY rates across the EU (3.5%). In addition, “mental disorders” showed an increasing age-standardised YLL rate (14.5%). Conclusions: There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease.
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-06-14T17:05:38Z
dc.date.available.none.fl_str_mv 2024-06-14T17:05:38Z
dc.date.issued.none.fl_str_mv 2024
dc.type.none.fl_str_mv Artículo de revista
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dc.identifier.citation.none.fl_str_mv Santos, J. V., Padron-Monedero, A., Bikbov, B., Grad, D. A., Plass, D., Mechili, E. A., Gazzelloni, F., Fischer, F., Sulo, G., Ngwa, C. H., Noguer-Zambrano, I., Peñalvo, J. L., Haagsma, J. A., Kissimova-Skarbek, K., Monasta, L., Ghith, N., Sarmiento-Suarez, R., Hrzic, R., Haneef, R., . . . Devleesschauwer, B. (2024). The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019. BMC Public Health, 24(1). https://doi.org/10.1186/s12889-024-18529-3
dc.identifier.uri.none.fl_str_mv https://repository.udca.edu.co/handle/11158/5820
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1186/s12889-024-18529-3
dc.identifier.eissn.none.fl_str_mv 14712458
identifier_str_mv Santos, J. V., Padron-Monedero, A., Bikbov, B., Grad, D. A., Plass, D., Mechili, E. A., Gazzelloni, F., Fischer, F., Sulo, G., Ngwa, C. H., Noguer-Zambrano, I., Peñalvo, J. L., Haagsma, J. A., Kissimova-Skarbek, K., Monasta, L., Ghith, N., Sarmiento-Suarez, R., Hrzic, R., Haneef, R., . . . Devleesschauwer, B. (2024). The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019. BMC Public Health, 24(1). https://doi.org/10.1186/s12889-024-18529-3
14712458
url https://repository.udca.edu.co/handle/11158/5820
https://doi.org/10.1186/s12889-024-18529-3
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.citationedition.none.fl_str_mv (Dic., 2024) Artículo número 1374
dc.relation.citationendpage.none.fl_str_mv 19
dc.relation.citationissue.none.fl_str_mv 1
dc.relation.citationstartpage.none.fl_str_mv 1
dc.relation.citationvolume.none.fl_str_mv 24
dc.relation.ispartofjournal.none.fl_str_mv BMC Public Health
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spelling Santos, João Vascovirtual::102-1Padron-Monedero, Aliciavirtual::103-1Bikbov, Borisvirtual::104-1Matias de Oliveira, Alecsandravirtual::105-1Plass, DietrichMechili, Enkeleint A.virtual::106-1GAZZELLONI, Federicavirtual::107-1Fischer, Florianvirtual::108-1Sulo, GerhardNgwa, Che HenryNoguer-Zambrano, IsabelPenalvo, Jose Lvirtual::110-12024-06-14T17:05:38Z2024-06-14T17:05:38Z2024Santos, J. V., Padron-Monedero, A., Bikbov, B., Grad, D. A., Plass, D., Mechili, E. A., Gazzelloni, F., Fischer, F., Sulo, G., Ngwa, C. H., Noguer-Zambrano, I., Peñalvo, J. L., Haagsma, J. A., Kissimova-Skarbek, K., Monasta, L., Ghith, N., Sarmiento-Suarez, R., Hrzic, R., Haneef, R., . . . Devleesschauwer, B. (2024). The state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019. BMC Public Health, 24(1). https://doi.org/10.1186/s12889-024-18529-3https://repository.udca.edu.co/handle/11158/5820https://doi.org/10.1186/s12889-024-18529-314712458Background: The European Union (EU) faces many health-related challenges. Burden of diseases information and the resulting trends over time are essential for health planning. This paper reports estimates of disease burden in the EU and individual 27 EU countries in 2019, and compares them with those in 2010. Methods: We used the Global Burden of Disease 2019 study estimates and 95% uncertainty intervals for the whole EU and each country to evaluate age-standardised death, years of life lost (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) rates for Level 2 causes, as well as life expectancy and healthy life expectancy (HALE). Results: In 2019, the age-standardised death and DALY rates in the EU were 465.8 deaths and 20,251.0 DALYs per 100,000 inhabitants, respectively. Between 2010 and 2019, there were significant decreases in age-standardised death and YLL rates across EU countries. However, YLD rates remained mainly unchanged. The largest decreases in age-standardised DALY rates were observed for “HIV/AIDS and sexually transmitted diseases” and “transport injuries” (each -19%). “Diabetes and kidney diseases” showed a significant increase for age-standardised DALY rates across the EU (3.5%). In addition, “mental disorders” showed an increasing age-standardised YLL rate (14.5%). Conclusions: There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease.Incluye referencias bibliográficasapplication/pdfenghttps://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.eshttps://creativecommons.org/licenses/by-nc-sa/4.0/Atribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)http://purl.org/coar/access_right/c_abf2https://link.springer.com/content/pdf/10.1186/s12889-024-18529-3.pdf360 - Problemas y servicios sociales; asociaciones::362 - Problemas sociales y servicios para grupo de personasMujeresHombresCosto de la EnfermedadUnion EuropeaCarga Global de EnfermedadesEstado de SaludEsperanza de VidaAños de vida Ajustados por la IncapacidadThe state of health in the European Union (EU-27) in 2019: a systematic analysis for the Global Burden of Disease study 2019Artículo de 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jecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.</li>
      <li>
        Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:
        <ol type="i">
          <li>Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.</li>
          <li>Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.</li>
        </ol>
      </li>
      <li>Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.</li>
    </ol>
  </li>
  <br/>
  <li>
    Representaciones, Garantías y Limitaciones de Responsabilidad.
    <p>A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.</p>
  </li>
  <br/>
  <li>
    Limitación de responsabilidad.
    <p>A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.</p>
  </li>
  <br/>
  <li>
    Término.
    <ol type="a">
      <li>Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.</li>
      <li>Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.</li>
    </ol>
  </li>
  <br/>
  <li>
    Varios.
    <ol type="a">
      <li>Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.</li>
      <li>Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.</li>
      <li>Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.</li>
      <li>Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.</li>
    </ol>
  </li>
  <br/>
</ol>
