Interferón tau en la ventana de reconocimiento materno embrionario bovino

Maternal-embryonic recognition is one of the most important events in bovine reproduction. This process is regulated by multiple cellular and endocrine signals among the embryo, the endometrium and corpus luteum, the most important transitory gland in the maternal-embryonic recognition window since it is responsible for the production of progesterone. Bovine trophoblastic interferon (bINT-T) named after the site of production (embryonic trofoectoderm) is the main signal for the successful establishment of pregnancy. bINT-T, supports functional and structural luteotropic process ensuring the production of progesterone and integrity of the cells forming the corpus luteum. Luteolysis is divided in two stages: Functional and structural luteolysis, both mediated primarily by PGF2a. Luteolysis is necessary for maintenance of the estrous cycle cyclicity. Once luteolitic mechanisms initiate, the chances of maintaining the pregnancy are reduced. Among the main efects of bINT-T, are the inhibition of the synthesis and pulsatile release of PGF2a in the bovine endometrium which consists of two types of cells: endometrial epithelial cells (CEEP) and endometrial stromal cells (CEES). The former produces between 60 to 70% of the total PGF2a. The purpose of this review is to describe the role of bINT-Tin the maternal-embryonic recognition window and its major effects on the synthesis and secretion of PGE2 and PGF2a in the bovine endometrium.

• Autores: Yasser, Lenis; Ramón, Nicolás; Restrepo, Juan; Olivera, Matha; Tarazona, Ariel
• Tipo de recurso: Article of journal
• Fecha de publicación: 2010
• Institución: Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
• Repositorio: Repositorio Institucional UDCA
• Idioma: spa
• OAI Identifier: oai:repository.udca.edu.co:11158/2224
• Acceso en línea: https://revistas.udca.edu.co/index.php/ruadc/article/view/705
• Palabra clave: Embrión; Luteólisis; Luteotropism; Trofoblasto; Luteólisis; LH; Embriones animales; Bovina
• Rights: openAccess
• License: Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales