Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública

La clamidiasis aviar o psitacosis, causada por la bacteria Chlamydia psittaci, es una enfermedad zoonótica infecciosa que afecta a gran cantidad de aves. Existen múltiples reportes a nivel mundial sobre la bacteria en aves psitácidas, sin embargo, en el país hay pocas investigaciones. Ante esta situ...

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Autores:
Moyano Ayala, Norela
Tipo de recurso:
Trabajo de grado de pregrado
Fecha de publicación:
2021
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
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spa
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oai:repository.udca.edu.co:11158/3808
Acceso en línea:
https://repository.udca.edu.co/handle/11158/3808
Palabra clave:
Zoonosis
Chlamydophila psittaci
Psittaciformes
Aves
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openAccess
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id RepoUDCA2_52a8ba807467f2bd777a6465b1ea93dc
oai_identifier_str oai:repository.udca.edu.co:11158/3808
network_acronym_str RepoUDCA2
network_name_str Repositorio Institucional UDCA
repository_id_str
dc.title.spa.fl_str_mv Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
title Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
spellingShingle Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
Zoonosis
Chlamydophila psittaci
Psittaciformes
Aves
title_short Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
title_full Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
title_fullStr Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
title_full_unstemmed Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
title_sort Hallazgos clínicos y paraclínicos y su correlación con la detección molecular de Chlamydiapsittaci en aves Psitácidas del centro de recepción de fauna temporal del Distrito y una aproximación a los posibles riegos de salud pública
dc.creator.fl_str_mv Moyano Ayala, Norela
dc.contributor.advisor.none.fl_str_mv Falla Beltrán, Ana Carolina, dir.
dc.contributor.author.none.fl_str_mv Moyano Ayala, Norela
dc.subject.lemb.none.fl_str_mv Zoonosis
topic Zoonosis
Chlamydophila psittaci
Psittaciformes
Aves
dc.subject.agrovoc.none.fl_str_mv Chlamydophila psittaci
Psittaciformes
Aves
description La clamidiasis aviar o psitacosis, causada por la bacteria Chlamydia psittaci, es una enfermedad zoonótica infecciosa que afecta a gran cantidad de aves. Existen múltiples reportes a nivel mundial sobre la bacteria en aves psitácidas, sin embargo, en el país hay pocas investigaciones. Ante esta situación, este estudio es uno de los primeros en Colombia en abordar el manejo de las aves psitácidas expuestas a C. psittaci. En este trabajo se estudian algunas variables epidemiológicas, signos clínicos, hallazgos de hematología y coprología en aves y su correlación con el hallazgo de Chlamydia psittaci en pruebas moleculares en 177 aves del estudio de Ruiz (2020). Adicionalmente, en vista del potencial zoonótico, se realizó la aproximación al riesgo de salud pública en 21 trabajadores del Centro de Fauna Silvestre Temporal de Bogotá. Como resultado, se obtuvo que la frecuencia respiratoria baja fue significativa para los resultados (hisopado cloacal, materia fecal y consolidado); y la presencia de plumaje quebrado fue significativa para los resultados de las muestras de hisopado cloacal. En las pruebas hematológicas dos aves presentaron varios hallazgos relacionados con la infección y en las pruebas coprológicas no se encontró ningún hallazgo relacionado. Por su parte, respecto a los trabajadores del centro se obtuvo una alta presencia de la bacteria (85,7%) y varios aspectos epidemiológicos relacionados con los resultados positivos para la infección. A partir del estudio se generó un protocolo para el manejo y la toma de muestras aplicable a los distintos centros que manejan aves psitácidas bajo cuidado humano y fue posible dilucidar la importancia de una metodología de manejo estandarizada y de un examen clínico cuidadoso en aves psitácidas positivas a Chlamydia psittaci
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-02-10T16:25:15Z
dc.date.available.none.fl_str_mv 2021-02-10T16:25:15Z
dc.date.issued.none.fl_str_mv 2021-02
dc.type.Es_es.fl_str_mv Trabajo de grado - Pregrado
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.Es_es.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.driver.Es_es.fl_str_mv info:eu-repo/semantics/bachelorThesis
dc.type.version.Es_es.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.content.Es_es.fl_str_mv Text
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dc.identifier.uri.none.fl_str_mv https://repository.udca.edu.co/handle/11158/3808
dc.identifier.instname.Es_es.fl_str_mv Universidad de Ciencias Aplicadas y Ambientales
dc.identifier.reponame.Es_es.fl_str_mv UDCA
dc.identifier.repourl.Es_es.fl_str_mv repository.udca.edu.co
url https://repository.udca.edu.co/handle/11158/3808
identifier_str_mv Universidad de Ciencias Aplicadas y Ambientales
UDCA
repository.udca.edu.co
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spelling Falla Beltrán, Ana Carolina, dir.Moyano Ayala, NorelaBogotá, Colombia2021-02-10T16:25:15Z2021-02-10T16:25:15Z2021-02https://repository.udca.edu.co/handle/11158/3808Universidad de Ciencias Aplicadas y AmbientalesUDCArepository.udca.edu.coLa clamidiasis aviar o psitacosis, causada por la bacteria Chlamydia psittaci, es una enfermedad zoonótica infecciosa que afecta a gran cantidad de aves. Existen múltiples reportes a nivel mundial sobre la bacteria en aves psitácidas, sin embargo, en el país hay pocas investigaciones. Ante esta situación, este estudio es uno de los primeros en Colombia en abordar el manejo de las aves psitácidas expuestas a C. psittaci. En este trabajo se estudian algunas variables epidemiológicas, signos clínicos, hallazgos de hematología y coprología en aves y su correlación con el hallazgo de Chlamydia psittaci en pruebas moleculares en 177 aves del estudio de Ruiz (2020). Adicionalmente, en vista del potencial zoonótico, se realizó la aproximación al riesgo de salud pública en 21 trabajadores del Centro de Fauna Silvestre Temporal de Bogotá. Como resultado, se obtuvo que la frecuencia respiratoria baja fue significativa para los resultados (hisopado cloacal, materia fecal y consolidado); y la presencia de plumaje quebrado fue significativa para los resultados de las muestras de hisopado cloacal. En las pruebas hematológicas dos aves presentaron varios hallazgos relacionados con la infección y en las pruebas coprológicas no se encontró ningún hallazgo relacionado. Por su parte, respecto a los trabajadores del centro se obtuvo una alta presencia de la bacteria (85,7%) y varios aspectos epidemiológicos relacionados con los resultados positivos para la infección. A partir del estudio se generó un protocolo para el manejo y la toma de muestras aplicable a los distintos centros que manejan aves psitácidas bajo cuidado humano y fue posible dilucidar la importancia de una metodología de manejo estandarizada y de un examen clínico cuidadoso en aves psitácidas positivas a Chlamydia psittaciAvian chlamydia or psittacosis, caused by the bacteria Chlamydia psittaci, is an infectious zoonotic disease that affects large numbers of birds. There are multiple reports worldwide about this bacteria in psittacine birds, however, there are few researches in the country. Given this situation, this study is one of the first in Colombia to address the management of psittacine birds exposed to C. psittaci. This work studies some epidemiological variables, clinical signs, findings of hematology and coprology samples in birds and its correlation with the finding of Chlamydia psittaci in molecular tests in 177 birds of Ruiz's study (2020). Additionally, considering the zoonotic potential, the public health risk was addressed in 21 workers of the Temporary Wildlife Center of Bogotá. As a result, low respiratory frequency was significant for the results (cloacal swab, fecal and consolidated matter); and the presence of broken plumage was significant for the results of the cloacal swab samples. Two birds presented several findings related to infection on hematological tests and no related findings were found on stool tests. On the other hand, regarding the workers of the center, there was a high presence of the bacteria (85.7%) and several epidemiological aspects related to the positive results for the infection. 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en las Obras Colectivas;
b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda;
c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas.Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).
4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:
a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).
b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.
c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.
d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:
i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.
ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.
e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, Acinpro), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.
5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.
6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.
7. Término.
a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.
b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.
8. Varios.
a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.
b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.
c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.
d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.



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