Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados

The atelectasis during anesthesia affects gas exchange in humans and animals; this can be corrected using alveo-lar recruitment maneuvers (MRA). This study evaluated the effect of two cyclic alveolar recruitment protocols by increas-ing the positive end expiratory pressure (PEEP) on six param-eters...

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Autores:
Buriticá Gaviria, Edwin
Echeverry Bonilla, Diego
Ospina Argüelles, Diego
Tipo de recurso:
Article of journal
Fecha de publicación:
2016
Institución:
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio:
Repositorio Institucional UDCA
Idioma:
spa
OAI Identifier:
oai:repository.udca.edu.co:11158/1755
Acceso en línea:
https://revistas.udca.edu.co/index.php/ruadc/article/view/123
https://doi.org/10.31910/rudca.v19.n1.2016.123
Palabra clave:
Anestesia en veterinaria
Anestesia
Atelectasia
Gasometría
Oxigenación
Ventilación manual
Perro
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openAccess
License
Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales, 2016
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dc.title.spa.fl_str_mv Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
dc.title.alternative.spa.fl_str_mv Effect of two manual cyclical alveolar recruitment maneuvers on the value of blood gases in anesthetized dogs
title Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
spellingShingle Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
Anestesia en veterinaria
Anestesia
Atelectasia
Gasometría
Oxigenación
Ventilación manual
Perro
title_short Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
title_full Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
title_fullStr Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
title_full_unstemmed Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
title_sort Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiados
dc.creator.fl_str_mv Buriticá Gaviria, Edwin
Echeverry Bonilla, Diego
Ospina Argüelles, Diego
dc.contributor.author.spa.fl_str_mv Buriticá Gaviria, Edwin
Echeverry Bonilla, Diego
Ospina Argüelles, Diego
dc.subject.lemb.spa.fl_str_mv Anestesia en veterinaria
topic Anestesia en veterinaria
Anestesia
Atelectasia
Gasometría
Oxigenación
Ventilación manual
Perro
dc.subject.proposal.spa.fl_str_mv Anestesia
Atelectasia
Gasometría
Oxigenación
Ventilación manual
dc.subject.agrovoc.spa.fl_str_mv Perro
description The atelectasis during anesthesia affects gas exchange in humans and animals; this can be corrected using alveo-lar recruitment maneuvers (MRA). This study evaluated the effect of two cyclic alveolar recruitment protocols by increas-ing the positive end expiratory pressure (PEEP) on six param-eters of arterial blood gases in 28 anesthetized bitches. The animals were randomly distributed into two groups accord-ing to the alveolar recruitment maneuver (MRA) to perform; Group 1: Maneuver 1 (M1) recruited with PEEP of 10cmH2O and group 2: Maneuver 2 (M2) with PEEP 20cmH2O recruit-ed with 20 cmH2O PEEP. Cyclic maneuvers were performed using ambulatory manual breathing units (AMBU). The PaO2, PaCO2, TCO2, PaO2/ FiO2, SpO2 y CaO2 values wasanalyzed for each MRA in four times; T1 (baseline in preanesthesia), T2 (before of the recruitment), T3 (30 minutes after maneu-ver) and T4 (24 hours after maneuver). In the T2 moment the PaO2, PaCO2, TCO2, SpO2 andCaO2 values showed a significant increase (p<0.05) from T1 baseline moment. No significant changes were apparent after performing each ma-neuver in the time T3 of evaluation; however, there was a significant increase (p <0.05) in PaO2 of 13.5% in the time T4 after making the M2 maneuver. From which we conclude that the performance of alveolar recruitment maneuvers by artificial manual breathing units - AMBU are a safe alternative to assisted ventilation during alveolar recruitment maneuvers with PEEP lower than 20cmH2O in clinically healthy animals.
publishDate 2016
dc.date.issued.spa.fl_str_mv 2016-01
dc.date.accessioned.spa.fl_str_mv 2019-07-09T14:34:10Z
dc.date.available.spa.fl_str_mv 2019-07-09T14:34:10Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.doi.spa.fl_str_mv https://doi.org/10.31910/rudca.v19.n1.2016.123
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url https://revistas.udca.edu.co/index.php/ruadc/article/view/123
https://doi.org/10.31910/rudca.v19.n1.2016.123
dc.language.iso.spa.fl_str_mv spa
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dc.relation.ispartofseries.spa.fl_str_mv Revista UDCA : Actualidad & Divulgación Científica (Bogotá). -- Vol. 19, No. 1 (Ene.-Jun. 2016). -- páginas 161-168
dc.relation.indexed.spa.fl_str_mv Agricultura
dc.rights.spa.fl_str_mv Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales, 2016
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spelling Buriticá Gaviria, EdwinEcheverry Bonilla, DiegoOspina Argüelles, Diego2019-07-09T14:34:10Z2019-07-09T14:34:10Z2016-010123-4226https://revistas.udca.edu.co/index.php/ruadc/article/view/123https://doi.org/10.31910/rudca.v19.n1.2016.123304504The atelectasis during anesthesia affects gas exchange in humans and animals; this can be corrected using alveo-lar recruitment maneuvers (MRA). This study evaluated the effect of two cyclic alveolar recruitment protocols by increas-ing the positive end expiratory pressure (PEEP) on six param-eters of arterial blood gases in 28 anesthetized bitches. The animals were randomly distributed into two groups accord-ing to the alveolar recruitment maneuver (MRA) to perform; Group 1: Maneuver 1 (M1) recruited with PEEP of 10cmH2O and group 2: Maneuver 2 (M2) with PEEP 20cmH2O recruit-ed with 20 cmH2O PEEP. Cyclic maneuvers were performed using ambulatory manual breathing units (AMBU). The PaO2, PaCO2, TCO2, PaO2/ FiO2, SpO2 y CaO2 values wasanalyzed for each MRA in four times; T1 (baseline in preanesthesia), T2 (before of the recruitment), T3 (30 minutes after maneu-ver) and T4 (24 hours after maneuver). In the T2 moment the PaO2, PaCO2, TCO2, SpO2 andCaO2 values showed a significant increase (p<0.05) from T1 baseline moment. No significant changes were apparent after performing each ma-neuver in the time T3 of evaluation; however, there was a significant increase (p <0.05) in PaO2 of 13.5% in the time T4 after making the M2 maneuver. From which we conclude that the performance of alveolar recruitment maneuvers by artificial manual breathing units - AMBU are a safe alternative to assisted ventilation during alveolar recruitment maneuvers with PEEP lower than 20cmH2O in clinically healthy animals.Las atelectasias durante la realización de procedimientos anestésicos afecta el intercambio gaseoso en seres humanos y en animales. Esta condición, se puede corregir, empleando maniobras de reclutamiento alveolar. El presente estudio evaluó el efecto de dos protocolos cíclicos de reclutamiento alveolar, mediante el incremento de la presión tele-espiratoria (PEEP), sobre seis parámetros de gases arteriales, en 28 caninos anestesiados. Los animales fueron asignados aleatoriamente en dos grupos, según la maniobra de reclutamiento alveolar (MRA) a realizar; grupo 1: Maniobra 1 (M1), reclutado con PEEP de 10cmH2O y grupo 2: Maniobra 2 (M2), reclutado con PEEP de 20cmH2O. Las MRA, se realizaron empleando una unidad de respiración artificial manual (AMBU). Para cada maniobra, se evaluó la PaO2, PaCO2, TCO2, PaO2/ FiO2, SpO2 y CaO2, en cuatro tiempos a saber: T1 (basal en preanestesia), T2 (pre-reclutamiento), T3 (30 min post-maniobra) y T4 (24 h post-maniobra). En el tiempo T2, los valores de PaO2, PaCO2, TCO2, SpO2 y CaO2 presentaron un incremento significativo (p<0,05), respecto al tiempo basal T1. No se evidenciaron cambios estadísticos significativos tras realizar cada una de las MRA en el tiempo T3; sin embargo, hubo un incremento significativo (p<0,05) en la PaO2, de 13,5% y la PaO2/FiO2, del 13,5%, en el tiempo T4, tras realizar la maniobra M2. Se concluye, que la realización de MRA, mediante el empleo de AMBU, es una alternativa económica y segura de ventilación asistida, tras su empleo con PEEP inferiores a 20cm H2O, en animales clínicamente sanos.Incluye referencias bibliográficasapplication/pdfspaBogotá : Universidad de Ciencias Aplicadas y Ambientales, 2016Revista UDCA : Actualidad & Divulgación Científica (Bogotá). -- Vol. 19, No. 1 (Ene.-Jun. 2016). -- páginas 161-168AgriculturaDerechos Reservados - Universidad de Ciencias Aplicadas y Ambientales, 2016https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)http://purl.org/coar/access_right/c_abf2Efecto de dos maniobras manuales cíclicas de reclutamiento alveolar sobre gases sanguíneos en perros anestesiadosEffect of two manual cyclical alveolar recruitment maneuvers on the value of blood gases in anesthetized dogsArtículo de 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 nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.
d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:
i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.
ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.
e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, Acinpro), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.
5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.
6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.
7. Término.
a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.
b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.
8. Varios.
a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.
b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.
c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.
d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.

