Eventos adversos reportados por Prednisona y Prednisolona al Programa Distrital de Farmacovigilancia en Bogotá D.C, entre el 2009 al 31 de Agosto de 2017

SUMMARY The drugs subject of pharmacovigilance study by the authors are prednisolone and prednisone, synthetic corticosteroids derived from cortisol, widely used for various specialties due to their high efficacy and benefits in many medical situations exerting their actions as immunosuppressants and anti-inflammatories. study since in clinical practice it is evident that these drugs are sometimes used indiscriminately, without taking into account the pathology to be treated, its severity, duration of treatment, its metabolization and / or adequate characteristics of the drug, since This drug is prescribed in complex pathologies (lupus erythematosus, rheumatoid arthritis, prostate cancer) and often require chronic use, as it is known that the action of a drug can be altered, by the action of food, by the same disease, by characteristics unique to the patient, by interaction with other medications or by the prolonged use of them, producing adverse effects, some with more incidence than others and that can even reach death. For the development of this project, a cross-sectional descriptive study of the data of adverse events to prednisolone or prednisone reported to the Bogotá district health program was carried out. The variables described were related to factors of person, time, place and those of Adverse events, for the period under study from 2009 to August 31, 2017. The results obtained from the District Pharmacovigilance program in Bogotá were grouped taking into account variables such as age, gender, ADR, causality, severity and severity, PRM, therapeutic failure among others. The pharmacovigilance reports related to the prednisolone and prednisone drugs, represented 236 cases in which the majority of adverse reactions were caused to female patients between the age range of 50 - 54 years and greater than 75, most of the adverse reactions were They related symptoms such as headache, Rash, Cushing syndrome, drowsiness, dizziness, infection, erythema, pain, among others, and a small portion due to more severe reactions such as kidney failure and diabetes; symptoms related to the literature, and that occur during therapy or even after the treatment has ended. Likewise it was found that 10% of the reports corresponded to problems related to medications, many of these cases were due to errors at the time of dispensing, problems of the places destined to the delivery of the medication due to confusing the prescribed dose, human errors that they should be minimized to the maximum to ensure that the patient receives the appropriate medication in the proper dose. It is considered highly significant to initiate processes aimed at raising awareness among patients, as well as the medical team taking into account that these should be responsible for encouraging and motivating the patient, as well as being receptive to the information provided by patients within the treatment. verbal or written for the purpose of obtaining timely information about the adverse events that could occur due to the consumption of these medications. To assist with the training and awareness of the pharmacological monitoring process, it will be attached as Annex 1. An educational poster, with information concerning the possible adverse events and symptoms that each patient could present when using the medication in order to optimize the use of the group of medicines and provide the correct and necessary care to be able to watch over and preserve the patient's health

• Autores: Martínez Tinjacá, Jaris Paola; Gamboa Jiménez, Ana Silvia
• Tipo de recurso: Trabajo de grado de pregrado
• Fecha de publicación: 2017
• Institución: Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
• Repositorio: Repositorio Institucional UDCA
• Idioma: spa
• OAI Identifier: oai:repository.udca.edu.co:11158/856
• Acceso en línea: https://repository.udca.edu.co/handle/11158/856
• Palabra clave: Corticoides; Prednisona; Prednisolona; Reacciones adversas; Antiinflamatorios; Síndrome de Cusing; Osteoporosis; Diabetes mellitus; Prednisolona -- Efectos secundarios; Prednisona -- Efectos secundarios; Medicamentos -- Efectos secundarios
• Rights: closedAccess
• License: Derechos Reservados - Universidad de Ciencias Aplicadas y Ambientales