Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana

El mosquito Aedes aegypti presenta características biológicas que lo convierten en un vector importante en el ciclo de transmisión de diferentes patógenos, en especial arbovirus. Durante la última década, la carga de dengue y otras enfermedades tales como la fiebre del zika o fiebre chikungunya se h...

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Autores:
Gómez García, Giovan Fernando
Tipo de recurso:
Article of investigation
Fecha de publicación:
2018
Institución:
Tecnológico de Antioquia
Repositorio:
Repositorio Tdea
Idioma:
spa
OAI Identifier:
oai:dspace.tdea.edu.co:tdea/3823
Acceso en línea:
https://dspace.tdea.edu.co/handle/tdea/3823
Palabra clave:
Enfermedades emergentes
Emerging diseases
Maladie émergente
Globalización
Globalization
Mondialisation
Globalização
Organismos patógenos
Pathogens
Agent pathogène
Agente patogénio
Aedes aegypti
Enfermedades Transmitidas por Vectores
Vector Borne Diseases
Doenças Transmitidas por Vetores
Maladies vectorielles
Enfermedades Transmisibles Emergentes
Communicable Diseases, Emerging
Doenças Transmissíveis Emergentes
Maladies transmissibles émergentes
Infecciones por Arbovirus
Arbovirus Infections
Infecções por Arbovirus
Infections à arbovirus
Epidemias
Epidemics
Épidémies
Enfermedades vectoriales
Vector-borne diseases
Arbovirosis
Arboviral diseases
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openAccess
License
https://creativecommons.org/licenses/by-nc/4.0/
id RepoTdea2_6e07af35aa845d2343c4e1f5b2ccc5b5
oai_identifier_str oai:dspace.tdea.edu.co:tdea/3823
network_acronym_str RepoTdea2
network_name_str Repositorio Tdea
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dc.title.none.fl_str_mv Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
dc.title.translated.none.fl_str_mv Aedes (Stegomyia) aegypti (Diptera: Culicidae) and its importance for human health
title Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
spellingShingle Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
Enfermedades emergentes
Emerging diseases
Maladie émergente
Globalización
Globalization
Mondialisation
Globalização
Organismos patógenos
Pathogens
Agent pathogène
Agente patogénio
Aedes aegypti
Enfermedades Transmitidas por Vectores
Vector Borne Diseases
Doenças Transmitidas por Vetores
Maladies vectorielles
Enfermedades Transmisibles Emergentes
Communicable Diseases, Emerging
Doenças Transmissíveis Emergentes
Maladies transmissibles émergentes
Infecciones por Arbovirus
Arbovirus Infections
Infecções por Arbovirus
Infections à arbovirus
Epidemias
Epidemics
Épidémies
Enfermedades vectoriales
Vector-borne diseases
Arbovirosis
Arboviral diseases
title_short Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
title_full Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
title_fullStr Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
title_full_unstemmed Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
title_sort Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humana
dc.creator.fl_str_mv Gómez García, Giovan Fernando
dc.contributor.author.none.fl_str_mv Gómez García, Giovan Fernando
dc.subject.agrovoc.none.fl_str_mv Enfermedades emergentes
Emerging diseases
Maladie émergente
Globalización
Globalization
Mondialisation
Globalização
Organismos patógenos
Pathogens
Agent pathogène
Agente patogénio
topic Enfermedades emergentes
Emerging diseases
Maladie émergente
Globalización
Globalization
Mondialisation
Globalização
Organismos patógenos
Pathogens
Agent pathogène
Agente patogénio
Aedes aegypti
Enfermedades Transmitidas por Vectores
Vector Borne Diseases
Doenças Transmitidas por Vetores
Maladies vectorielles
Enfermedades Transmisibles Emergentes
Communicable Diseases, Emerging
Doenças Transmissíveis Emergentes
Maladies transmissibles émergentes
Infecciones por Arbovirus
Arbovirus Infections
Infecções por Arbovirus
Infections à arbovirus
Epidemias
Epidemics
Épidémies
Enfermedades vectoriales
Vector-borne diseases
Arbovirosis
Arboviral diseases
dc.subject.decs.none.fl_str_mv Aedes aegypti
Enfermedades Transmitidas por Vectores
Vector Borne Diseases
Doenças Transmitidas por Vetores
Maladies vectorielles
Enfermedades Transmisibles Emergentes
Communicable Diseases, Emerging
Doenças Transmissíveis Emergentes
Maladies transmissibles émergentes
Infecciones por Arbovirus
Arbovirus Infections
Infecções por Arbovirus
Infections à arbovirus
Epidemias
Epidemics
Épidémies
dc.subject.proposal.none.fl_str_mv Enfermedades vectoriales
Vector-borne diseases
Arbovirosis
Arboviral diseases
description El mosquito Aedes aegypti presenta características biológicas que lo convierten en un vector importante en el ciclo de transmisión de diferentes patógenos, en especial arbovirus. Durante la última década, la carga de dengue y otras enfermedades tales como la fiebre del zika o fiebre chikungunya se han incrementado, y nueva información acerca del papel de Ae. aegypti en la transmisión de estas enfermedades ha sido publicada. Este trabajo se enfocó en revisar mediante una estrategia de búsqueda sistemática de la información, el conocimiento actual de la historia evolutiva y otros aspectos biológicos de Ae. aegypti relacionados con la dinámica de transmisión de los principales arbovirus de importancia médica. Factores intrínsecos de Ae. aegypti y extrínsecos han contribuido a la emergencia o reemergencia y expansión mundial de patógenos en el ciclo urbano. El diseño de estrategias costo-efectivas para controlar Ae. aegypti es requerido para interrumpir los ciclos de transmisión de los patógenos y prevenir la aparición de nuevas epidemias. Palabras clave: Aedes aegypti; enfermedades vectoriales; enfermedades emergentes; arbovirosis; globalización.
publishDate 2018
dc.date.issued.none.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2023-08-30T22:56:01Z
dc.date.available.none.fl_str_mv 2023-08-30T22:56:01Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_dcae04bc
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/ARTREV
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.issn.spa.fl_str_mv 0375-0760
dc.identifier.uri.none.fl_str_mv https://dspace.tdea.edu.co/handle/tdea/3823
dc.identifier.eissn.spa.fl_str_mv 1561-3054
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url https://dspace.tdea.edu.co/handle/tdea/3823
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.citationendpage.spa.fl_str_mv 70
dc.relation.citationissue.spa.fl_str_mv 1
dc.relation.citationstartpage.spa.fl_str_mv 55
dc.relation.citationvolume.spa.fl_str_mv 70
dc.relation.ispartofjournal.spa.fl_str_mv Revista Cubana de Medicina Tropical
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spelling Gómez García, Giovan Fernandoba1c43f4-0c6e-4605-a4cf-720f028968022023-08-30T22:56:01Z2023-08-30T22:56:01Z20180375-0760https://dspace.tdea.edu.co/handle/tdea/38231561-3054El mosquito Aedes aegypti presenta características biológicas que lo convierten en un vector importante en el ciclo de transmisión de diferentes patógenos, en especial arbovirus. Durante la última década, la carga de dengue y otras enfermedades tales como la fiebre del zika o fiebre chikungunya se han incrementado, y nueva información acerca del papel de Ae. aegypti en la transmisión de estas enfermedades ha sido publicada. Este trabajo se enfocó en revisar mediante una estrategia de búsqueda sistemática de la información, el conocimiento actual de la historia evolutiva y otros aspectos biológicos de Ae. aegypti relacionados con la dinámica de transmisión de los principales arbovirus de importancia médica. Factores intrínsecos de Ae. aegypti y extrínsecos han contribuido a la emergencia o reemergencia y expansión mundial de patógenos en el ciclo urbano. El diseño de estrategias costo-efectivas para controlar Ae. aegypti es requerido para interrumpir los ciclos de transmisión de los patógenos y prevenir la aparición de nuevas epidemias. Palabras clave: Aedes aegypti; enfermedades vectoriales; enfermedades emergentes; arbovirosis; globalización.Due to its biological characteristics, the mosquito Aedes aegypti is an important vector in the transmission cycle of various pathogens, especially of arboviruses. The burden of dengue and other diseases such as Zika virus infection or chikungunya fever has increased in the last decade, and new information has been published about the role of A. aegypti in the transmission of these diseases. Applying a strategy for systematic search of information, the study focused on reviewing current knowledge about the evolutionary history and other biological aspects of A. aegypti associated with the dynamics of transmission of the main arboviruses of medical importance. Intrinsic and extrinsic factors related to A. aegypti have contributed to the emergence or re-emergence and worldwide spread of pathogens in the urban cycle. Cost-effective A. aegypti control strategies should be designed to interrupt the transmission cycles of pathogens and prevent the emergence of new epidemics. Keywords: Aedes aegypti; vector-borne diseases; emerging diseases; arboviral diseases; globalization.16 páginasapplication/pdfspaCentro Nacional de Información de Ciencias MédicasCubahttps://creativecommons.org/licenses/by-nc/4.0/Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2https://revmedtropical.sld.cu/index.php/medtropical/article/view/214/193Aedes (Stegomyia) aegypti (Diptera: Culicidae) y su importancia en salud humanaAedes (Stegomyia) aegypti (Diptera: Culicidae) and its importance for human healthArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/resource_type/c_dcae04bcTextinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTREVinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a857015570Revista Cubana de Medicina Tropical1. Sutherst RW. Global Change and Human Vulnerability to Vector-Borne Diseases. 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Investigation of an epidemic of acute febrile illness on the river Guama in Para, Brazil, and isolation of Mayaro virus as causative agent. Am J Trop Med Hyg. 1957;6:1017-1023.82. Long KC, Ziegler SA, Thangamani S, Hausser NL, Kochel TJ, Higgs S, et al. Experimental transmission of Mayaro virus by Aedes aegypti. Am J Trop Med Hyg. 2011;85(4):750-7.83. Serra OP, Fernandes Cardoso B, Maria Ribeiro AL, dos Santos FAL, Dezengrini Slhessarenko R, Cardoso BF, et al. Mayaro virus and dengue virus 1 and 4 natural infection in culicids from Cuiabá, state of Mato Grosso, Brazil. Mem Inst Oswaldo Cruz [Internet]. 2016 [cited 2017 Mar 29];111(1):20-9. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005028101&lng=en&nrm=iso&tlng=en84. Sanmartin-Barberi C, Groot H, Osorno-Mesa E. Human epidemic in Colombia caused by the Venezuelan equine encephalomyelitis virus. Am J Trop Med Hyg. 1954;3(2):283-93.85. Aguilar PV, Estrada-Franco JG, Navarro-Lopez R, Ferro C, Haddow AD, Weaver SC. Endemic Venezuelan equine encephalitis in the Americas: hidden under the dengue umbrella. Future Virol. 2011;6(6):721-40.86. Ortiz DI, Kang W, Weaver SC. Susceptibility of Ae. aegypti (Diptera: Culicidae) to infection with epidemic (subtype IC) and enzootic (subtypes ID, IIIC, IIID) Venezuelan equine encephalitis complex alphaviruses. J Med Entomol. 2008;45(6):1117-25.Enfermedades emergentesEmerging diseasesMaladie émergenteGlobalizaciónGlobalizationMondialisationGlobalizaçãoOrganismos patógenosPathogensAgent pathogèneAgente patogénioAedes aegyptiEnfermedades Transmitidas por VectoresVector Borne DiseasesDoenças Transmitidas por VetoresMaladies vectoriellesEnfermedades Transmisibles EmergentesCommunicable Diseases, EmergingDoenças Transmissíveis EmergentesMaladies transmissibles émergentesInfecciones por ArbovirusArbovirus InfectionsInfecções por ArbovirusInfections à arbovirusEpidemiasEpidemicsÉpidémiesEnfermedades vectorialesVector-borne diseasesArbovirosisArboviral diseasesTHUMBNAILAedes _Stegomyia_aegypti _Diptera- Culicidae_ y su importancia en salud humana.pdf.jpgAedes _Stegomyia_aegypti _Diptera- Culicidae_ y su importancia en salud humana.pdf.jpgGenerated 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 incorporada en las Obras Colectivas.

b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.

c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).

4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:

a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).

b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.

c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.

d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:

i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.

ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.

e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.

5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

7. Término.

a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.

b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.

8. Varios.

a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.

b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.

c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.

d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.


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