Español
Clavulanic acid is a metabolite widely used with different combinations of antibiotics to counteract different infectious diseases. This metabolite is not produced in Colombia in spite of having a great demand at national level, apparently due to its high production costs and the little information...
- Autores:
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Universidad Católica de Pereira
- Repositorio:
- Repositorio Institucional - RIBUC
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.ucp.edu.co:10785/13718
- Acceso en línea:
- https://revistas.ucp.edu.co/index.php/entrecienciaeingenieria/article/view/2830
http://hdl.handle.net/10785/13718
- Palabra clave:
- Rights
- openAccess
- License
- Derechos de autor 2023 Entre Ciencia e Ingeniería
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2023-08-29T03:49:43Z2023-08-29T03:49:43Z2023-07-10https://revistas.ucp.edu.co/index.php/entrecienciaeingenieria/article/view/283010.31908/19098367.2830http://hdl.handle.net/10785/13718Clavulanic acid is a metabolite widely used with different combinations of antibiotics to counteract different infectious diseases. This metabolite is not produced in Colombia in spite of having a great demand at national level, apparently due to its high production costs and the little information available on the global process. In this research, different literature reports are used to present a generalized scheme of the production of this metabolite and, with the help of Aspen plus software, the implementation of a model to simulate the production process, including pretreatment, production and post-treatment or purification stages. The model is very useful to analyze costs or to evaluate eventual changes in the production process, constituting a useful tool for the study and understanding of the process, as well as for decision making regarding its eventual implementation.El Ácido Clavulánico es un metabolito ampliamente utilizado con distintas combinaciones de antibióticos para contrarrestar diferentes enfermedades infecciosas. Este metabolito no se produce en Colombia a pesar de tener una gran demanda a nivel nacional, aparentemente debido a sus altos costos de producción y a la poca información que se tiene del proceso global. En esta investigación se usan diferentes reportes de la literatura para presentar un esquema generalizado de la producción de este metabolito y, con ayuda del software Aspen plus, la implementación de un modelo para simular el proceso de producción, incluyendo etapas de pretratamiento, producción y postratamiento o purificación. El modelo resulta de gran utilidad para analizar costos o evaluar eventuales cambios en el proceso de producción, constituyendo una herramienta útil para el estudio y entendimiento del proceso, así como para la toma de decisiones frente a su eventual implementación.application/pdfspaUniversidad Católica de Pereirahttps://revistas.ucp.edu.co/index.php/entrecienciaeingenieria/article/view/2830/2621Derechos de autor 2023 Entre Ciencia e Ingenieríahttps://creativecommons.org/licenses/by-nc/4.0/deed.es_EShttps://creativecommons.org/licenses/by-nc/4.0/deed.es_ESinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Entre ciencia e ingeniería; Vol 17 No 33 (2023); 55-62Entre Ciencia e Ingeniería; Vol. 17 Núm. 33 (2023); 55-62Entre ciencia e ingeniería; v. 17 n. 33 (2023); 55-622539-41691909-8367EspañolSimulación del proceso de producción de ácido clavulánicoArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionBedoya Betancur, Santiago AlexanderArdila Arias, Alba NellyBarrera Zapata, RolandoPublication10785/13718oai:repositorio.ucp.edu.co:10785/137182025-01-27 18:58:47.46https://creativecommons.org/licenses/by-nc/4.0/deed.es_ESDerechos de autor 2023 Entre Ciencia e Ingenieríametadata.onlyhttps://repositorio.ucp.edu.coRepositorio Institucional de la Universidad Católica de Pereira - RIBUCbdigital@metabiblioteca.com |
| dc.title.eng.fl_str_mv |
Español |
| dc.title.spa.fl_str_mv |
Simulación del proceso de producción de ácido clavulánico |
| title |
Español |
| spellingShingle |
Español |
| title_short |
Español |
| title_full |
Español |
| title_fullStr |
Español |
| title_full_unstemmed |
Español |
| title_sort |
Español |
| description |
Clavulanic acid is a metabolite widely used with different combinations of antibiotics to counteract different infectious diseases. This metabolite is not produced in Colombia in spite of having a great demand at national level, apparently due to its high production costs and the little information available on the global process. In this research, different literature reports are used to present a generalized scheme of the production of this metabolite and, with the help of Aspen plus software, the implementation of a model to simulate the production process, including pretreatment, production and post-treatment or purification stages. The model is very useful to analyze costs or to evaluate eventual changes in the production process, constituting a useful tool for the study and understanding of the process, as well as for decision making regarding its eventual implementation. |
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2023 |
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2023-08-29T03:49:43Z |
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2023-08-29T03:49:43Z |
| dc.date.issued.none.fl_str_mv |
2023-07-10 |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_6501 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_6501 |
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https://revistas.ucp.edu.co/index.php/entrecienciaeingenieria/article/view/2830 10.31908/19098367.2830 |
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http://hdl.handle.net/10785/13718 |
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https://revistas.ucp.edu.co/index.php/entrecienciaeingenieria/article/view/2830 http://hdl.handle.net/10785/13718 |
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10.31908/19098367.2830 |
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spa |
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spa |
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https://revistas.ucp.edu.co/index.php/entrecienciaeingenieria/article/view/2830/2621 |
| dc.rights.spa.fl_str_mv |
Derechos de autor 2023 Entre Ciencia e Ingeniería https://creativecommons.org/licenses/by-nc/4.0/deed.es_ES |
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https://creativecommons.org/licenses/by-nc/4.0/deed.es_ES |
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info:eu-repo/semantics/openAccess |
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Derechos de autor 2023 Entre Ciencia e Ingeniería https://creativecommons.org/licenses/by-nc/4.0/deed.es_ES http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
Universidad Católica de Pereira |
| dc.source.eng.fl_str_mv |
Entre ciencia e ingeniería; Vol 17 No 33 (2023); 55-62 |
| dc.source.spa.fl_str_mv |
Entre Ciencia e Ingeniería; Vol. 17 Núm. 33 (2023); 55-62 |
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Entre ciencia e ingeniería; v. 17 n. 33 (2023); 55-62 |
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2539-4169 1909-8367 |
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Universidad Católica de Pereira |
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Repositorio Institucional de la Universidad Católica de Pereira - RIBUC |
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bdigital@metabiblioteca.com |
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1831929529523765248 |