Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021

Objetivo: Determinar la calidad de vida relacionada a la salud (CVRS) y los desenlaces funcionales a 30, 60 y 90, días de pacientes supervivientes a sepsis no COVID en terapia intensiva, de dos instituciones de la red pública de Barranquilla, en el período de enero a abril del 2021. Métodos: Estudio...

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Autores:: Díaz Alcendra, Oscar Javier
García Ballesteros, Emerson Javier

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Fecha de publicación:: 2022

Institución:: Universidad Libre

Repositorio:: RIU - Repositorio Institucional UniLibre

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dc.title.spa.fl_str_mv	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
title	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
spellingShingle	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021 Calidad de vida Sepsis Funcionalidad Re-hospitalización Morbilidades Quality of life Sepsis Functionality Re-hospitalization Morbidities Calidad de vida Sepsis Infecciones
title_short	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
title_full	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
title_fullStr	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
title_full_unstemmed	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
title_sort	Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021
dc.creator.fl_str_mv	Díaz Alcendra, Oscar Javier García Ballesteros, Emerson Javier
dc.contributor.advisor.none.fl_str_mv	Fernández Chica, Dinno Navarro Baene, Gina
dc.contributor.author.none.fl_str_mv	Díaz Alcendra, Oscar Javier García Ballesteros, Emerson Javier
dc.subject.spa.fl_str_mv	Calidad de vida Sepsis Funcionalidad Re-hospitalización Morbilidades
topic	Calidad de vida Sepsis Funcionalidad Re-hospitalización Morbilidades Quality of life Sepsis Functionality Re-hospitalization Morbidities Calidad de vida Sepsis Infecciones
dc.subject.subjectenglish.spa.fl_str_mv	Quality of life Sepsis Functionality Re-hospitalization Morbidities
dc.subject.lemb.spa.fl_str_mv	Calidad de vida Sepsis Infecciones
description	Objetivo: Determinar la calidad de vida relacionada a la salud (CVRS) y los desenlaces funcionales a 30, 60 y 90, días de pacientes supervivientes a sepsis no COVID en terapia intensiva, de dos instituciones de la red pública de Barranquilla, en el período de enero a abril del 2021. Métodos: Estudio longitudinal, y retrospectivo, en el que se incluyeron pacientes supervivientes a sepsis con seguimiento a 30, 60 y 90 días para evaluar la CVRS y los desenlaces funcionales Resultados: La muestra estuvo representada por 78 pacientes. Durante los 30 primeros días ocurrió la mayor tasa de re-hospitalizaciones (23%). El 50% de los pacientes presentó valores de 2 o superior en el índice de Charlson, llegando a valores cercanos a 6 para el 75% de la muestra. La CVRS se encontró disminuida en la dimensión física a 30 días (35,92 ± 9,48) a los 60 días (39,35 ± 7,25) y a 90 días (40,50 ± 6,59). Para la dimensión mental, la media del puntaje de SF-12 fue de 46,70 ± 11,75 a los 30 días, 43,82 ± 8,24 a los 60 días y 42,27 ± 7,68 a los 90 días. Con una variación significativa entre los puntajes SF-12 y los tiempos evaluados, tanto para la valoración física (p<0,05) como mental (p<0,05). El porcentaje de Independencia se encontró disminuido a los 30 días (69,07± 21,95), 60 dias (76,20 ± 19,11) y 90 días (79,11 ± 18,87) p= <0,05. Conclusión: En los pacientes supervivientes a hospitalización por sepsis, la calidad de vida relacionada a la salud y la independencia funcional estuvieron considerablemente disminuidas en el tiempo de seguimiento. La independencia funcional se relacionó directamente con el componente físico de la calidad de vida.
publishDate	2022
dc.date.accessioned.none.fl_str_mv	2022-12-05T20:01:05Z
dc.date.available.none.fl_str_mv	2022-12-05T20:01:05Z
dc.date.created.none.fl_str_mv	2022
dc.type.coar.fl_str_mv	http://purl.org/coar/resource_type/c_7a1f
dc.type.local.spa.fl_str_mv	Tesis de Especialización
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/bachelorThesis
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/10901/23837
url	https://hdl.handle.net/10901/23837
dc.relation.references.spa.fl_str_mv	WHO Quality of Life Assessment Group. (1996). ¿Qué es calidad de vida? / Grupo de la OMS sobre la calidad de vida. Foro mundial de la salud 1996 ; 17(4) : 385-387 Villaverde ML, Fernández L, Gracia R, Morera A, Cejas R. Salud mental en población institucionalizada mayor de 65 años en la isla de Tenerife. Rev Esp Geriatr Gerontol 2000; 35(5):277-282 Labib A. Sepsis Care Pathway 2019. Qatar Med J. 2019 Nov 7;2019(2):4. doi: 10.5339/qmj.2019.qccc.4 Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, et al. Global, regional, and national sepsis incidence and mortality, 1990 – 2017: analysis for the Global Burden of Disease Study. Lancet [Internet]. 2020;395(10219):200–11 Rudd KE, Kissoon N, Limmathurotsakul D, Bory S, Mutahunga B, Seymour CW, et al. The global burden of sepsis: barriers and potential solutions. Crit Care. 2018 Sep 23;22(1):232. doi: 10.1186/s13054-018-2157-z Ministerio de Salud y Protección Social. Análisis de Situación de Salud (ASIS) 2018. Colombia, Bogotá D.C., Colombia, 2019 pp.224-230 Torio CM, Andrews RM. National inpatient hospital costs: the most expensive conditions by payer, 2011: statistical brief #160. Healthcare Cost and Utilization Project (HCUP) statistical briefs. Rockville, MD: United States Agency for Health Care Policy and Research; 2006 Angus DC, Lind-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States analysis of incidence outcome, and associated costs. Crit Care Med 2001;29:1303–10 Mostel, Z., Perl, A., Marck, M. et al. Post-sepsis syndrome – an evolving entity that afflicts survivors of sepsis. Mol Med 2020; 26, 6 Vincent JL, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet. 2013;381(9868):774–5 Secretaria Distrital de Salud Pública. Análisis de Situación de Salud con el Modelo de los determinantes Sociales de Salud 2018. Barranquilla: Distrito de Barranquilla; 2018 pp.62-63 Barrera L, Rosa GD La, Dennis R, Dueñas C, Granados M, London D, et al. The epidemiology of sepsis in Colombia: A prospective multicenter cohort study in ten university hospitals Crit Care Med 2011;39(7):1675–82 Steenbergen et al. Long-term treated intensive care patients outcomes: the one-year mortality rate, quality of life, health care use and long-term complications as reported by general practitioners BMC Anesthesiology (2015) 15:142 Schmidt K et al. Effect of a primary care management intervention on mentalhealth-related quality of life among survivors of sepsis: a randomized clinical trial. JAMA. 2016; 315(24): 2703–2711 Wang HE, Jones AR, Donnelly JP. Revised National Estimates of Emergency Department Visits for Sepsis in the United States. Crit Care Med. 2017 Sep;45(9):1443-1449. doi: 10.1097/CCM.0000000000002538 Erbs, G. C., Mastroeni, M. F., Pinho, M. S. L., Koenig, Á., Sperotto, G., Ekwaru, J. P., & Westphal, G. A. Comorbidities Might Condition the Recovery of Quality of Life in Survivors of Sepsis. Journal of Intensive Care Medicine, 2017;1-7. 088506661769936 Luethi N, Bailey M, A. Higgins, et al., Gender differences in mortality and quality of life after septic shock: A post-hoc analysis of the ARISE study, Journal of Critical Care(2019), https://doi.org/10.1016/j.jcrc.2019.11.002 Nannan Panday RS, Minderhoud TC, Chantalou DS, Alam N, Nanayakkara PWB. Health related quality of life in sepsis survivors from the Prehospital Antibiotics Against Sepsis (PHANTASi) trial. PLoS One. 2019 oct 1;14(10):e0222450. doi: 10.1371/journal.pone.0222450 Puthucheary, Z. A., Gensichen, J. S., Cakiroglu, A. S., Cashmore, R., Edbrooke, L., Heintze, C., Schmidt, K. F. R. Implications for post critical illness trial design: sub-phenotyping trajectories of functional recovery among sepsis survivors. Critical Care, 2020. 24(1). doi:10.1186/s13054-020-03275-w Dalager-Pedersen M, Thomsen RW, Schønheyder HC, Nielsen H. Functional status and quality of life after community-acquired bacteraemia: a matched cohort study. Clin Microbiol Infect. 2016 Jan;22(1):78.e1-78.e8 Carey M., Prescott H., Iwashyna T., Wilson M. Changes in Self-Rated Health After Sepsis in Older Adults A Retrospective Cohort Study. CHEST 2020;xx(x):x-x https://doi.org/10.1016/j.chest.2020.05.606 Needham DM, Davidson J, Cohen H, et al. Improving long-term outcomes after discharge from intensive care units: report from a stakeholders’ conference. Crit Care Med 2012;40(2):502–9 Elliott D, Davidson JE, Harvey MA, et al. Exploring the scope of post-intensive care syndrome therapy and care: engagement of non-critical care providers and survivors in a second stakeholder meeting. Crit care Med 2014;42(12):2518–26 Dos Santos CC, Batt J. ICU-acquired weakness: mechanisms of disability. Curr Opin Crit Care 2012;18(5):509–17 Courtright KR, Jordan L, Murtaugh CM, et al. Risk factors for long-term mortality and patterns of end-of-life care among medicare sepsis survivors discharged to home healthcare. JAMA Netw Open 2020; 3:e200038 Shankar-Hari M, Harrison DA, Ferrando-Vivas P, et al. Risk factors at index hospitalization associated with longer-term mortality in adult sepsis survivors. JAMA Netw Open 2019; 2:e194900 Ortiz G, Dueñas C, Rodríguez F, Barrera L, de La Rosa G, Dennis R, et al. Epimediology of sepsis in Colombian Intensive care units. Biomédica: revista del Instituto Nacional de Salud. 2014; 34 (1): 40-7. Disponible en: https://www.researchgate.net/publication/271344480_Epidemiologia_de_la_ sepsis_en_unidades_ de_cuidado_intensivo_en_Colombia Enciso O, Guerra K. Costos de atención en UCI de un hospital universitario de Bogotá D. C. Repert. med. cir 2006; 15(3): 133-142 Wintermann GB, Brunkhorst FM, Petrowski K, et al. Stress disorders following prolonged critical illness in survivors of severe sepsis. Crit Care Med 2015; 43(6):1213–22 Desai SV, Law TJ, Needham DM. Long-term complications of critical care. Crit Care Med 2011;39: 371–9 Batt J, dos Santos CC, Cameron JI, et al. Intensive care unit-acquired weakness: clinical phenotypes and molecular mechanisms. Am J Respir Crit Care Med 2013;187(3):238–46 Ward PA. Immunosuppression in sepsis. JAMA 2011;306:2618–9 Simon PM, Delude RL, Lee M, et al, GenIMS Investigators. Duration and magnitude of hypotension and monocyte deactivation in patients with community-acquired pneumonia. Shock 2011;36: 553–9 Talmadge JE, Gabrilovich DI. History of myeloid-derived suppressor cells. Nat Rev Cancer 2013;13(10):739–52 Mathias B, Delmas AL, Ozrazgat-Baslanti T, et al. Human myeloid-derived suppressor cells are associated with chronic immune suppression after severe sepsis/septic shock. Ann Surg 2016. [Epub ahead of print] Mira JC, Gentile LF, Mathias BJ, et al. Sepsis pathophysiology, chronic critical illness, and persistent inflammation-immunosuppression and catabolism syndrome. Crit Care Med 2017;45(2):253–62 Walkey AJ, Hammill BG, Curtis LH, et al. Long-term outcomes following development of new-onset atrial fibrillation during sepsis. Chest 2014;146(5):1187–95 Levy MM, Evans LE, Rhodes A. The Surviving Sepsis Campaign Bundle: 2018 update. Intensive Care Med. 2018;44(6):925-928. doi:10.1007/s00134- 018-5085-0 Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF36) (I). Conceptual framework and item selection. Med Care. 1992;30:473-83 Vilagut G, et al. El Cuestionario de Salud SF-36 español: una década de experiencia y nuevos desarrollos. Gac Sanit. 2005;19(2):135-50 Annane D, Sharshar T. Cognitive decline after sepsis. Lancet Respir Med 2015;3(1):61–9 Gross AL, Jones RN, Habtemariam DA, et al. Delirium and long-term cognitive trajectory among persons with dementia. Arch Intern Med 2012; 172(17):1324–31 Rodriguez L; Saracco R; Escamilla R. Validez de la Escala de Evaluación Cognitiva de Montreal (MoCA) para determinar deterioro cognitivo. Salud Ment [online]. 2014, vol.37, n.6, pp.517-522. ISSN 0185-3325 Iwashyna TJ, Ely EW, Smith DM, et al. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA 2010;304:1787– 94 Vergara et al. Validation of the Spanish version of the Lawton IADL Scale for its application in elderly people. Health and Quality of Life Outcomes 2012, 10:130 Weinstein, M.; Torrance, G. & McGuire, A. “QALYs: The Basics”. Value in Health. European Journal of Health Economics. 2009. Vol. 12, Supplement 1. p S5-S9 Alvis N. Valenzuela M. Los QALYs y DALYs como indicadores sintéticos de salud. Rev. méd. Chile [online]. 2010, vol.138, suppl.2, pp.83-87. ISSN 0034- 9887 Alcaraz DA, Martínez G, Motos R. Diccionario terminológico de las ciencias farmacéuticas. España: Ariel; 2007 Winters BD, Eberlein M, Leung J, Needham DM, Pronovost PJ, Sevransky JE. Long-term mortality and quality of life in sepsis: a systematic review. Crit Care Med. 2010;38(5):1276- 1283 Hofhuis JGM, Spronk PE, van Stel HF, et al: The impact of severe sepsis on health-related quality of life: A long-term follow-up study. Anesth Analg 2008; 107:1957–1964 Winters BD, Eberlein M, Leung J, Needham DM, Pronovost PJ, Sevransky JE. Long-term mortality and quality of life in sepsis: a systematic review. Crit Care Med. 2010 May;38(5):1276-83 Cook WT, Eddleston JM, Conway D, et al: Quality of life in ICU survivors with severe sepsis who received activated protein C. Crit Care 2007; 7(Suppl 2):meeting abstract Sands KE, Bates DW, Lanken PN, et al: Epidemiology of sepsis syndrome in 8 academic medical centers. JAMA 1997; 278:234–240 Hofhuis JGM, Spronk PE, van Stel HF, et al: The impact of severe sepsis on health-related quality of life: A long-term follow-up study. Anesth Analg 2008; 107:1957–1964 Su, Y.-X., Xu, L., Gao, X.-J., Wang, Z.-Y., Lu, X., & Yin, C.-F. Long-term quality of life after sepsis and predictors of quality of life in survivors with sepsis. Chinese Journal of Traumatology, 2018; 21(4), 216–223 Davydow DS, Hough CL, Langa KM, Iwashyna TJ. Symptoms of depression in survivors of severe sepsis: a prospective cohort study of older Americans. Am J Geriatr Psychiatry. 2013;21(9):887–97 Gawlytta R, Niemeyer H, Bottche M, Scherag A, Knaevelsrud C, Rosendahl J. Internet-based cognitive-behavioural writing therapy for reducing posttraumatic stress after intensive care for sepsis in patients and their spouses (REPAIR): study protocol for a randomised-controlled trial. BMJ Open. 2017;7(2):e014363 DiPietro L. Physical activity in aging: changes in patterns and their relationship to health and function. J Gerontol A Biol Sci Med Sci. 2001;56 Spec No 2:13–22 Kessler RC, Bromet EJ. The epidemiology of depression across cultures. Annu Rev Public Health. 2013;34:119–38 Pacella ML, Hruska B, Delahanty DL. The physical health consequences of PTSD and PTSD symptoms: a meta-analytic review. J Anxiety Disord. 2013;27(1):33–46 Langa KM, Chernew ME, Kabeto MU, et al. National estimates of the quantity and cost of informal caregiving for the elderly with dementia. J Gen Intern Med. 2001;16(11):770–8 Rozzini R, Sabatini T, Cassinadri A, et al. Relationship between functional loss before hospital admission and mortality in elderly persons with medical illness. J Gerontol A Biol Sci Med Sci. 2005;60(9):1180–3 Ramírez-Vélez R., Agredo-Zuñiga R., Jerez-Valderrama A. Confiabilidad y valores normativos preliminares del cuestionario de salud SF-12 (Short Form 12 Health Survey) en adultos colombianos. Rev. salud pública. 2010; 12 (5): 807-819
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spelling	Fernández Chica, DinnoNavarro Baene, GinaDíaz Alcendra, Oscar JavierGarcía Ballesteros, Emerson JavierBarranquilla2022-12-05T20:01:05Z2022-12-05T20:01:05Z2022https://hdl.handle.net/10901/23837Objetivo: Determinar la calidad de vida relacionada a la salud (CVRS) y los desenlaces funcionales a 30, 60 y 90, días de pacientes supervivientes a sepsis no COVID en terapia intensiva, de dos instituciones de la red pública de Barranquilla, en el período de enero a abril del 2021. Métodos: Estudio longitudinal, y retrospectivo, en el que se incluyeron pacientes supervivientes a sepsis con seguimiento a 30, 60 y 90 días para evaluar la CVRS y los desenlaces funcionales Resultados: La muestra estuvo representada por 78 pacientes. Durante los 30 primeros días ocurrió la mayor tasa de re-hospitalizaciones (23%). El 50% de los pacientes presentó valores de 2 o superior en el índice de Charlson, llegando a valores cercanos a 6 para el 75% de la muestra. La CVRS se encontró disminuida en la dimensión física a 30 días (35,92 ± 9,48) a los 60 días (39,35 ± 7,25) y a 90 días (40,50 ± 6,59). Para la dimensión mental, la media del puntaje de SF-12 fue de 46,70 ± 11,75 a los 30 días, 43,82 ± 8,24 a los 60 días y 42,27 ± 7,68 a los 90 días. Con una variación significativa entre los puntajes SF-12 y los tiempos evaluados, tanto para la valoración física (p<0,05) como mental (p<0,05). El porcentaje de Independencia se encontró disminuido a los 30 días (69,07± 21,95), 60 dias (76,20 ± 19,11) y 90 días (79,11 ± 18,87) p= <0,05. Conclusión: En los pacientes supervivientes a hospitalización por sepsis, la calidad de vida relacionada a la salud y la independencia funcional estuvieron considerablemente disminuidas en el tiempo de seguimiento. La independencia funcional se relacionó directamente con el componente físico de la calidad de vida.Universidad Libre Seccional Barranquilla -- Facultad de Ciencias de la Salud -- Especialización en Medicina InternaObjective: To determine the health-related quality of life (HRQoL) and functional outcomes at 30, 60 and 90 days in patients surviving non-COVID sepsis in intensive care, in two institutions of the public network of Barranquilla, in the period from January to April 2021. Methods: Longitudinal, retrospective study including sepsis survivors with 30, 60 and 90-day follow-up to assess HRQoL and functional outcomes. Results: The sample consisted of 78 patients. The highest rate of rehospitalization occurred during the first 30 days (23%). Fifty percent of the patients presented values of 2 or higher in the Charlson index, reaching values close to 6 for 75% of the sample. HRQOL was found to be decreased in the physical dimension at 30 days (35.92 ± 9.48) at 60 days (39.35 ± 7.25) and at 90 days (40.50 ± 6.59). For the mental dimension, the mean SF-12 score was 46.70 ± 11.75 at 30 days, 43.82 ± 8.24 at 60 days and 42.27 ± 7.68 at 90 days. With significant variation between SF-12 scores and times evaluated, both for physical (p<0.05) and mental (p<0.05) assessment. The percentage of Independence was found to be decreased at 30 days (69.07± 21.95), 60 days (76.20 ± 19.11) and 90 days (79.11 ± 18.87) p= <0.05. Conclusion: In patients surviving hospitalization for sepsis, health-related quality of life and functional independence were significantly decreased at follow-up time. Functional independence was directly related to the physical component of quality of life.PDFhttp://creativecommons.org/licenses/by-nc-nd/2.5/co/Atribución-NoComercial-SinDerivadas 2.5 Colombiahttp://purl.org/coar/access_right/c_abf2Calidad de vidaSepsisFuncionalidadRe-hospitalizaciónMorbilidadesQuality of lifeSepsisFunctionalityRe-hospitalizationMorbiditiesCalidad de vidaSepsisInfeccionesCalidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021Tesis de Especializacióninfo:eu-repo/semantics/bachelorThesishttp://purl.org/coar/resource_type/c_7a1fWHO Quality of Life Assessment Group. (1996). ¿Qué es calidad de vida? / Grupo de la OMS sobre la calidad de vida. Foro mundial de la salud 1996 ; 17(4) : 385-387Villaverde ML, Fernández L, Gracia R, Morera A, Cejas R. Salud mental en población institucionalizada mayor de 65 años en la isla de Tenerife. Rev Esp Geriatr Gerontol 2000; 35(5):277-282Labib A. Sepsis Care Pathway 2019. Qatar Med J. 2019 Nov 7;2019(2):4. doi: 10.5339/qmj.2019.qccc.4Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, et al. Global, regional, and national sepsis incidence and mortality, 1990 – 2017: analysis for the Global Burden of Disease Study. Lancet [Internet]. 2020;395(10219):200–11Rudd KE, Kissoon N, Limmathurotsakul D, Bory S, Mutahunga B, Seymour CW, et al. The global burden of sepsis: barriers and potential solutions. Crit Care. 2018 Sep 23;22(1):232. doi: 10.1186/s13054-018-2157-zMinisterio de Salud y Protección Social. Análisis de Situación de Salud (ASIS) 2018. Colombia, Bogotá D.C., Colombia, 2019 pp.224-230Torio CM, Andrews RM. National inpatient hospital costs: the most expensive conditions by payer, 2011: statistical brief #160. Healthcare Cost and Utilization Project (HCUP) statistical briefs. Rockville, MD: United States Agency for Health Care Policy and Research; 2006Angus DC, Lind-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States analysis of incidence outcome, and associated costs. Crit Care Med 2001;29:1303–10Mostel, Z., Perl, A., Marck, M. et al. Post-sepsis syndrome – an evolving entity that afflicts survivors of sepsis. Mol Med 2020; 26, 6Vincent JL, Opal SM, Marshall JC, Tracey KJ. Sepsis definitions: time for change. Lancet. 2013;381(9868):774–5Secretaria Distrital de Salud Pública. Análisis de Situación de Salud con el Modelo de los determinantes Sociales de Salud 2018. Barranquilla: Distrito de Barranquilla; 2018 pp.62-63Barrera L, Rosa GD La, Dennis R, Dueñas C, Granados M, London D, et al. The epidemiology of sepsis in Colombia: A prospective multicenter cohort study in ten university hospitals Crit Care Med 2011;39(7):1675–82Steenbergen et al. Long-term treated intensive care patients outcomes: the one-year mortality rate, quality of life, health care use and long-term complications as reported by general practitioners BMC Anesthesiology (2015) 15:142Schmidt K et al. Effect of a primary care management intervention on mentalhealth-related quality of life among survivors of sepsis: a randomized clinical trial. JAMA. 2016; 315(24): 2703–2711Wang HE, Jones AR, Donnelly JP. Revised National Estimates of Emergency Department Visits for Sepsis in the United States. Crit Care Med. 2017 Sep;45(9):1443-1449. doi: 10.1097/CCM.0000000000002538Erbs, G. C., Mastroeni, M. F., Pinho, M. S. L., Koenig, Á., Sperotto, G., Ekwaru, J. P., & Westphal, G. A. Comorbidities Might Condition the Recovery of Quality of Life in Survivors of Sepsis. Journal of Intensive Care Medicine, 2017;1-7. 088506661769936Luethi N, Bailey M, A. 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Rev. salud pública. 2010; 12 (5): 807-819THUMBNAILCALIDAD DE VIDA Y DESENLACES FUNCIONALES EN SEPSIS UCI.pdf.jpgCALIDAD DE VIDA Y DESENLACES FUNCIONALES EN SEPSIS UCI.pdf.jpgIM Thumbnailimage/jpeg12739http://repository.unilibre.edu.co/bitstream/10901/23837/3/CALIDAD%20DE%20VIDA%20Y%20DESENLACES%20FUNCIONALES%20EN%20SEPSIS%20UCI.pdf.jpgb1adbf14023ea355a65fa76507705fcbMD53LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://repository.unilibre.edu.co/bitstream/10901/23837/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALCALIDAD DE VIDA Y DESENLACES FUNCIONALES EN SEPSIS UCI.pdfCALIDAD DE VIDA Y DESENLACES FUNCIONALES EN SEPSIS UCI.pdfapplication/pdf1219920http://repository.unilibre.edu.co/bitstream/10901/23837/1/CALIDAD%20DE%20VIDA%20Y%20DESENLACES%20FUNCIONALES%20EN%20SEPSIS%20UCI.pdfa5ebc955cc2aba22fdd536ca9f1c691cMD5110901/23837oai:repository.unilibre.edu.co:10901/238372023-08-03 11:48:56.739Repositorio Institucional Unilibrerepositorio@unilibrebog.edu.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

Calidad de vida relacionada a la salud y desenlaces funcionales a 30, 60 y 90 días de pacientes supervivientes a sepsis en terapia intensiva de dos instituciones de la red pública de Barranquilla enero – abril 2021

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